专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5352800A Process for the production of a novel endothelin antagonist 失效
标题翻译：用于生产新型内皮素拮抗剂的方法
公开(公告)号：US5352800A
公开(公告)日：1994-10-04
申请号：US29745
申请日：1993-03-11
申请人： Gerard F. Bills , Michael A. Goetz , Robert A. Giacobbe , Lucia Herranz , E. Tracy Turner Jones , Fernando Pelaez , Yu L. Kong , Sheo B. Singh , Siobhan Stevens-Miles
发明人： Gerard F. Bills , Michael A. Goetz , Robert A. Giacobbe , Lucia Herranz , E. Tracy Turner Jones , Fernando Pelaez , Yu L. Kong , Sheo B. Singh , Siobhan Stevens-Miles
IPC分类号： C07D207/38 , C07D207/273
CPC分类号： C07D207/38 , Y10S435/911
摘要： Fermentation processes for the production of a compound of the Structural Formula I ##STR1## The compound of Structural Formula I has been shown to have endothelin antagonist activity and is therefore useful in treating cardiovascular disorders, such as hypertension, congestive heart failure, postischemic renal failure vasospasm, cerebral and cardia ischemia, myocardial infarction inflammatory diseases, Raynaud's disease, endotoxin shock and asthma.
摘要翻译：用于制备结构式I化合物的发酵方法结构式I的化合物已显示具有内皮素拮抗剂活性，因此可用于治疗心血管疾病，例如高血压，充血性心力衰竭，缺血后肾脏失败的血管痉挛，脑和贲门缺血，心肌梗塞炎症性疾病，雷诺氏病，内毒素休克和哮喘。

2. 发明授权

US5276054A Substituted hexahydrobenzopyran derivatives as angiotensin II antagonists 失效
标题翻译：取代的六氢苯并吡喃衍生物作为血管紧张素II拮抗剂
公开(公告)号：US5276054A
公开(公告)日：1994-01-04
申请号：US961957
申请日：1992-10-16
申请人： Maria T. Diez , Michael A. Goetz , Robert A. Giacobbe , Otto D. Hensens , Leeyan Huang , Isabel Martin , E. Tracy T. Jones , Siobhan Stevens-Miles , Yu L. Kong
发明人： Maria T. Diez , Michael A. Goetz , Robert A. Giacobbe , Otto D. Hensens , Leeyan Huang , Isabel Martin , E. Tracy T. Jones , Siobhan Stevens-Miles , Yu L. Kong
IPC分类号： C07D311/74 , C07D493/10 , A61K31/35 , C07D311/72 , C07D311/78
CPC分类号： C07D493/10 , C07D311/74
摘要： Substituted hexahydrobenzopyran derivatives of the Formulae A, B, or C are useful as angiotensin II antagonists: ##STR1##
摘要翻译：式A，B或C的取代的六氢苯并吡喃衍生物可用作血管紧张素II拮抗剂：（*化学结构*）A（*化学结构*）B（*化学结构*）C

3. 发明授权

US5712109A Antifungal agent produced by arthrinium arundinis ATCC 74359 失效
标题翻译：由arthrinium arundinis ATCC 74359生产的抗真菌剂
公开(公告)号：US5712109A
公开(公告)日：1998-01-27
申请号：US789348
申请日：1997-01-27
申请人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
发明人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
IPC分类号： C07J9/00 , C12P33/00 , A61K31/56 , C12N1/14
CPC分类号： C07J9/00
摘要： There is disclosed a compound having the formula ##STR1## which is produced by the fungus, Arthrinium arundinis ATCC 74359, and exhibits antifungal activity.
摘要翻译：公开了由真菌Arthrinium arundinis ATCC 74359产生的具有式（I）的化合物，并表现出抗真菌活性。

4. 发明授权

US5348970A Antifungal compound and compositions containing the compound 失效
标题翻译：抗真菌化合物和含有该化合物的组合物
公开(公告)号：US5348970A
公开(公告)日：1994-09-20
申请号：US125432
申请日：1993-09-22
申请人： Robert E. Schwartz , Janet C. Onishi , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez , Maria T. Diez , Francisca Vicente , Julian Gorrochategui , Gregory L. Helms , Barnali Pramanik
发明人： Robert E. Schwartz , Janet C. Onishi , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez , Maria T. Diez , Francisca Vicente , Julian Gorrochategui , Gregory L. Helms , Barnali Pramanik
IPC分类号： C07D405/06 , A61K31/40
CPC分类号： C07D405/06
摘要： A compound of the formula 1: ##STR1## is produced via fermentation of a fungal isolate ATCC no. 74235. The organism is included herein, as well as a process for production of the compound, a pharmaceutical composition and a method of treatment.
摘要翻译：通过真菌分离物ATCC号的发酵产生式1化合物： 1。生物体包括在本文中，以及生产化合物的方法，药物组合物和治疗方法。

5. 发明授权

US5801172A Antifungal agent from sporomiella minimoides 失效
标题翻译：来自孢子虫的抗真菌剂
公开(公告)号：US5801172A
公开(公告)日：1998-09-01
申请号：US890772
申请日：1997-07-11
申请人： Wendy H. Clapp-Shapiro , Bruce W. Burgess , Robert A. Giacobbe , Guy H. Harris , Suzanne Mandala , Jon Polishook , Mark Rattray , Rosemary A. Thornton , Deborah L. Zink , Angeles Cabello , Maria Teresa Diez , Isabel Martin , Fernando Pelaez
发明人： Wendy H. Clapp-Shapiro , Bruce W. Burgess , Robert A. Giacobbe , Guy H. Harris , Suzanne Mandala , Jon Polishook , Mark Rattray , Rosemary A. Thornton , Deborah L. Zink , Angeles Cabello , Maria Teresa Diez , Isabel Martin , Fernando Pelaez
IPC分类号： A01N43/90 , A01N63/04 , C07K5/097 , C07D471/00 , A01N43/58
CPC分类号： C07K5/0821 , A01N43/90 , A01N63/04
摘要： There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.
摘要翻译：公开了具有抗真菌活性的具有式（I）＆lt; IMAGE＆gt;的式的新化合物。

6. 发明授权

US5756472A Antifungal agent obtained from hormonema 失效
标题翻译：从激素水解获得的抗真菌剂
公开(公告)号：US5756472A
公开(公告)日：1998-05-26
申请号：US789349
申请日：1997-01-27
申请人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Sandra A. Morris , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Wendy S. Horn , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
发明人： Jerrold M. Liesch , Maria S. Meinz , Janet C. Onishi , Sandra A. Morris , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Wendy S. Horn , Deborah L. Zink , Angeles Cabello , Maria T. Diez , Isabella Martin , Fernando Pelaez , Francisca Vicente
IPC分类号： C07H15/24 , A61K31/70 , C07D315/00 , C12N1/14
CPC分类号： C07H15/24 , Y10S435/911
摘要： There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.
摘要翻译：公开了具有抗真菌活性的具有式（I）＆lt; IMAGE＆gt;的式的新化合物。

7. 发明授权

US5461071A Anti-fungal agents 失效
标题翻译：抗真菌剂
公开(公告)号：US5461071A
公开(公告)日：1995-10-24
申请号：US326986
申请日：1994-10-21
申请人： Evon A. Bolessa , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez Perez , Angeles Cabello Arroyo , Teresa Diez Matas , Isabel Martin Fernandez , Francisca Vincente Perez , Suzanne M. Mandala , Deborah L. Zink , Rosemary Thornton , John R. Thompson , James E. Curotto
发明人： Evon A. Bolessa , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez Perez , Angeles Cabello Arroyo , Teresa Diez Matas , Isabel Martin Fernandez , Francisca Vincente Perez , Suzanne M. Mandala , Deborah L. Zink , Rosemary Thornton , John R. Thompson , James E. Curotto
IPC分类号： C07D207/12 , A61K31/40 , A61K31/445 , C07D211/40
CPC分类号： C07D207/12
摘要： A compound having the formula ##STR1## which is an anti-fungal agent is described. The producing organism Colletotricum accutatum is also described, along with a method of production.
摘要翻译：描述了具有抗真菌剂的式“IMAGE”的化合物。还描述了生产菌Colletotricum accutatum以及生产方法。

8. 发明授权

US5686637A Antifungal agent 失效
标题翻译：抗真菌剂
公开(公告)号：US5686637A
公开(公告)日：1997-11-11
申请号：US371171
申请日：1995-01-10
申请人： Gerald F. Bills , James E. Curotto , S. Dreikorn , Robert A. Giacobbe , Guy H. Harris , Suzanne Miller Mandala , Rosemary A. Thornton , Deborah L. Zink , Angeles Cabello Arroyo , Fernando Pelaez Perez , Teresa Diez Matas , Francisca Vicente Perez
发明人： Gerald F. Bills , James E. Curotto , S. Dreikorn , Robert A. Giacobbe , Guy H. Harris , Suzanne Miller Mandala , Rosemary A. Thornton , Deborah L. Zink , Angeles Cabello Arroyo , Fernando Pelaez Perez , Teresa Diez Matas , Francisca Vicente Perez
IPC分类号： C07C69/738 , C12P7/64 , C07C59/147
CPC分类号： C12P7/6463 , C07C69/738
摘要： There is disclosed a novel compound having the formula ##STR1## which exhibits antifungal activity.
摘要翻译：公开了具有抗真菌活性的具有式（I）＆lt; IMAGE＆gt;的式的新化合物。

9. 发明授权

US5543431A Anti-fungal agents 失效
公开(公告)号：US5543431A
公开(公告)日：1996-08-06
申请号：US449622
申请日：1995-05-24
申请人： Evon A. Bolessa , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez Perez , Angeles Cabello Arroyo , Teresa Diez Matas , Isabel Martin Fernandez , Francisca Vicente Perez , Suzanne M. Mandala , Deborah L. Zink , Rosemary Thornton , John R. Thompson , James E. Curotto
发明人： Evon A. Bolessa , Robert E. Schwartz , Gerald F. Bills , Robert A. Giacobbe , Fernando Pelaez Perez , Angeles Cabello Arroyo , Teresa Diez Matas , Isabel Martin Fernandez , Francisca Vicente Perez , Suzanne M. Mandala , Deborah L. Zink , Rosemary Thornton , John R. Thompson , James E. Curotto
IPC分类号： C07D207/12 , C07C233/09 , A61K31/16 , A61K31/695 , C07C233/20
CPC分类号： C07D207/12
摘要： A compound having the formula ##STR1## which is an anti-fungal agent is described. The producing organism Colletotricum accutatum is also described, along with a method of production.

10. 发明授权

US08224717B2 Managing an inventory of service parts 有权
标题翻译：管理服务部件的库存
公开(公告)号：US08224717B2
公开(公告)日：2012-07-17
申请号：US10862935
申请日：2004-06-08
申请人： Robert A. Giacobbe , R. Douglas Derrick
发明人： Robert A. Giacobbe , R. Douglas Derrick
IPC分类号： G06Q10/00 , G06F153/00
CPC分类号： G06Q10/06315 , G06Q10/087
摘要： An inventory of service parts may be managed by assessing a company's capability, optimizing the inventory and implementing a management program based on the assessment and optimization. Optimizing target stock levels for the inventory of parts may be accomplished by calculating an inventory baseline for understanding information about the currently held inventory; developing a service strategy for a set of segments; quantifying a service level for each of the segments; analyzing the segments and their service levels for identifying at least one logistically distinct business; assigning each of the segments to a “best-fit” planning model for indicating each segment's deployment, replenishment, forecasting and review characteristics; identifying a probability distribution function for estimating a demand process of each of the segments; and calculating a target stock level for each segment.
摘要翻译：可以通过评估公司的能力，优化库存和基于评估和优化实施管理程序来管理服务部件的库存。优化部件库存的目标库存水平可以通过计算库存基准来了解关于当前持有的库存的信息来实现; 制定一系列细分的服务策略; 量化每个细分的服务水平; 分析细分及其服务水平，以确定至少一个逻辑上不同的业务; 将每个分段分配给“最佳拟合”规划模型，以指示每个部分的部署，补充，预测和审查特征; 识别用于估计每个段的需求过程的概率分布函数; 并计算每个段的目标库存水平。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式