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    • 3. 发明授权
    • Cryosurgery device
    • 冷冻设备
    • US07604632B2
    • 2009-10-20
    • US11222353
    • 2005-09-08
    • Harold A. HowlettRobert C. JohnsonCharles E. Lundy, Jr.Eric Chen-nan Su
    • Harold A. HowlettRobert C. JohnsonCharles E. Lundy, Jr.Eric Chen-nan Su
    • A61B18/02
    • A61B18/0218
    • A cryosurgery device includes an aerosol container holding a liquid refrigerant and having a valve and a stem extending out therefrom; an actuator seated on the stem and including an outlet tube for receiving released refrigerant from the container; a hub mounted on the container and including slots therein; and a base having a central opening for receiving the hub, the base including aligning projections that enter the slots in the hub to engage and apply pressure to the actuator to cause the actuator to depress the stem and release refrigerant into the base. The container may further contain an applicator tube mounted to the hub in fluid communication with the outlet tube with a porous tip mounted to a distal end of the applicator tube for receiving the refrigerant and, being chilled thereby, applied to a skin lesion to be treated.
    • 冷冻手术装置包括保持液体制冷剂并具有从其延伸出的阀和杆的气溶胶容器; 安置在所述杆上并包括用于从所述容器接收释放的制冷剂的出口管的致动器; 安装在容器上并在其中包括槽的轮毂; 以及具有用于容纳轮毂的中心开口的底座,所述基座包括进入轮毂中的狭槽的对准突起,以接合并向致动器施加压力,以使致动器压下杆并将制冷剂释放到基座中。 容器还可以包含安装在毂上的施加器管,其与出口管流体连通,多孔尖端安装到施用管的远端,用于接收制冷剂,并由此冷却,施加到待治疗的皮肤损伤处 。
    • 4. 发明授权
    • Cryosurgery device
    • 冷冻设备
    • US08066698B2
    • 2011-11-29
    • US12402360
    • 2009-03-11
    • Harold A. HowlettRobert C. JohnsonCharles E. Lundy, Jr.Eric Chen-nan Su
    • Harold A. HowlettRobert C. JohnsonCharles E. Lundy, Jr.Eric Chen-nan Su
    • A61B18/02
    • A61B18/0218
    • A cryosurgery device includes an aerosol container holding a liquid refrigerant and having a valve and a stem extending out therefrom; an actuator seated on the stem and including an outlet tube for receiving released refrigerant from the container; a hub mounted on the container and including slots therein; and a base having a central opening for receiving the hub, the base including aligning projections that enter the slots in the hub to engage and apply pressure to the actuator to cause the actuator to depress the stem and release refrigerant into the base. The container may further contain an applicator tube mounted to the hub in fluid communication with the outlet tube with a porous tip mounted to a distal end of the applicator tube for receiving the refrigerant and, being chilled thereby, applied to a skin lesion to be treated.
    • 冷冻手术装置包括保持液体制冷剂并具有从其延伸出的阀和杆的气溶胶容器; 安置在所述杆上并包括用于从所述容器接收释放的制冷剂的出口管的致动器; 安装在容器上并在其中包括槽的轮毂; 以及具有用于容纳轮毂的中心开口的底座,所述基座包括进入轮毂中的狭槽的对准突起,以接合并向致动器施加压力,以使致动器压下杆并将制冷剂释放到基座中。 容器还可以包含安装在毂上的施加器管,其与出口管流体连通,多孔尖端安装到施用管的远端,用于接收制冷剂,并由此冷却,施加到待治疗的皮肤损伤处 。
    • 8. 发明授权
    • Overlaminated pressure-sensitive adhesive construction
    • 叠层压敏胶结构
    • US06270871B1
    • 2001-08-07
    • US09049376
    • 1998-03-27
    • William F. ScholzEric Chen-nan SuNorman A. ContiJohannes SchutDavid J. ScanlanSteven J. VargasRonald UgolickJose Luis MendezEdward I. Sun
    • William F. ScholzEric Chen-nan SuNorman A. ContiJohannes SchutDavid J. ScanlanSteven J. VargasRonald UgolickJose Luis MendezEdward I. Sun
    • G09F310
    • G09F3/10C09J7/35Y10T156/11Y10T428/14Y10T428/1405Y10T428/1452Y10T428/1462Y10T428/1471Y10T428/1476Y10T428/1486Y10T428/24851Y10T428/24868Y10T428/24876Y10T428/28Y10T428/2848
    • Overlaminated faceless PSA label constructions of this invention comprise a low material cost, thin prelaminate PSA construction having a layer of pressure-sensitive material disposed on a release surface of a removable substrate, and a nonblocking continuous film disposed over a surface of the layer of pressure-sensitive adhesive to render the pressure-sensitive adhesive tack free. An optically transparent overlaminate film layer is disposed over the nonblocking continuous film, and a printed indicia is interposed between the overlaminate film layer and nonblocking continuous film. The prelaminate PSA construction does not include a conventional facestock formed from paper, cardboard or plastic, and is highly conformable. The overlaminated film layer can be applied to the prelaminate faceless PSA construction by pressure lamination, via a further PSA layer interposed between continuous film and the overlaminate film layer, or by heat and pressure by forming one of the continuous film or overlaminate film layers from a heat-activatable material that itself forms a laminating adhesive surface. Alternatively, the overlaminate film layer can be applied to the prelaminate PSA construction as a film-forming material. The overlaminated PSA construction has a sufficient Gurley stiffness to permit high-speed converting and dispensing by peel plate equipment without sacrificing the high degree of conformity provided by the underlying prelaminate PSA construction.
    • 本发明的无覆盖的无标签PSA标签结构包括低材料成本,薄的预层压PSA结构,其具有设置在可移除基底的释放表面上的压敏材料层,以及设置在压力层表面上的非阻塞连续膜 敏感粘合剂,以使压敏粘合剂无粘性。 将光学透明的层叠膜设置在非阻挡连续膜上,印刷标记介于层叠膜层和非阻挡连续膜之间。 预层压PSA结构不包括由纸,纸板或塑料形成的常规面料,并且是高度一致的。 叠层膜可以通过压力层压,通过介于连续膜和层叠膜层之间的另一粘合剂层,或通过加热和压力,通过从一层连续膜或覆盖膜层中形成一层 本身形成层压粘合剂表面的可热激活的材料。 或者,叠层膜层可以作为成膜材料应用于预层压PSA结构。 叠层PSA结构具有足够的Gurley刚度,以允许剥离板设备进行高速转换和分配,而不会牺牲基础的预层压PSA结构提供的高度一致性。