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1. 发明授权

US08277867B2 Microdrop ablumenal coating system and method 有权
标题翻译：微滴覆膜系统及方法
公开(公告)号：US08277867B2
公开(公告)日：2012-10-02
申请号：US12208789
申请日：2008-09-11
申请人： Gerald Fredrickson , Bill Dorogy , Todd Robida , Paul Sojka
发明人： Gerald Fredrickson , Bill Dorogy , Todd Robida , Paul Sojka
IPC分类号： B05D1/04 , B05B5/035 , B05C11/02
CPC分类号： B05B5/025 , A61F2/82 , A61F2240/001 , A61F2250/0067 , B05B1/08 , B05B5/0533 , B05B13/0228 , B05B17/04 , B05B17/06 , B05D1/04
摘要： Systems and methods for coating medical devices are provided that allow for relatively precise control over the deposition area and coating uniformity with improved efficiency. A microdrop source is used to provide a flow of coating microdrops. A charging electrode disposed near the outlet of the coating source gives each microdrop an electrostatic charge. As the microdrop travels toward the medical device to be coated, a control electrode alters the trajectory of the microdrop. The invention can include a scanner to scan or image the medical device as the coating is applied and a control system to adjust parameters of the deposition process based on information provided by the scanner.
摘要翻译：提供用于涂覆医疗装置的系统和方法，其允许相对精确地控制沉积区域和涂层均匀性，同时提高效率。微滴源用于提供涂层微滴的流动。设置在涂层源的出口附近的充电电极给每个微滴静电电荷。当微滴向待涂覆的医疗装置行进时，控制电极改变微滴的轨迹。本发明可以包括扫描器，以便在施加涂层时扫描或成像医疗装置，以及控制系统，用于根据由扫描器提供的信息来调整沉积过程的参数。

2. 发明申请

US20090074943A1 MICRODROP ABLUMENAL COATING SYSTEM AND METHOD 有权
标题翻译： MICRODROP ABLUMENAL涂料体系及方法
公开(公告)号：US20090074943A1
公开(公告)日：2009-03-19
申请号：US12208789
申请日：2008-09-11
申请人： Gerald Fredrickson , Bill Dorogy , Todd R. Robida , Paul Sojka
发明人： Gerald Fredrickson , Bill Dorogy , Todd R. Robida , Paul Sojka
IPC分类号： B05D1/04 , B05B5/035 , B05C11/02
CPC分类号： B05B5/025 , A61F2/82 , A61F2240/001 , A61F2250/0067 , B05B1/08 , B05B5/0533 , B05B13/0228 , B05B17/04 , B05B17/06 , B05D1/04
摘要： Systems and methods for coating medical devices are provided that allow for relatively precise control over the deposition area and coating uniformity with improved efficiency. A microdrop source is used to provide a flow of coating microdrops. A charging electrode disposed near the outlet of the coating source gives each microdrop an electrostatic charge. As the microdrop travels toward the medical device to be coated, a control electrode alters the trajectory of the microdrop. The invention can include a scanner to scan or image the medical device as the coating is applied and a control system to adjust parameters of the deposition process based on information provided by the scanner.
摘要翻译：提供用于涂覆医疗装置的系统和方法，其允许相对精确地控制沉积区域和涂层均匀性，同时提高效率。微滴源用于提供涂层微滴的流动。设置在涂层源的出口附近的充电电极给每个微滴静电电荷。当微滴向待涂覆的医疗装置行进时，控制电极改变微滴的轨迹。本发明可以包括扫描器，以便在施加涂层时扫描或成像医疗装置，以及控制系统，用于根据由扫描器提供的信息来调整沉积过程的参数。

3. 发明授权

US08097291B2 Methods for coating workpieces 失效
标题翻译：涂装工件的方法
公开(公告)号：US08097291B2
公开(公告)日：2012-01-17
申请号：US11446262
申请日：2006-06-05
申请人： Gerald Fredrickson , Lan Pham , Marlene Schwarz , Todd Robida
发明人： Gerald Fredrickson , Lan Pham , Marlene Schwarz , Todd Robida
IPC分类号： B05D3/04 , B05D3/14 , B05D1/32
CPC分类号： B05D3/042 , A61L2420/02 , B05B5/082 , B05B12/18 , B05B13/02 , B05B13/0228 , B05B14/00 , B05D1/002 , B05D1/04
摘要： The present invention is directed to methods, processes, and systems for coating portions of a workpiece as well as to workpieces that have themselves been coated in accord with the invention. Under these methods and processes of the invention, a means to repel may be positioned on a mandrel prior to applying a coating to the workpiece. The means to repel may prevent the coating of a target surface of the workpiece.
摘要翻译：本发明涉及用于涂覆工件的部分以及本身已经根据本发明进行了涂覆的工件的方法，工艺和系统。在本发明的这些方法和方法下，在将涂层施加到工件之前，排斥装置可以定位在心轴上。排斥的方法可以防止工件的目标表面的涂覆。

4. 发明申请

US20070281092A1 Partially coated workpieces; methods and systems for making partially coated workpieces 失效
标题翻译：部分涂层工件; 制作部分涂层工件的方法和系统
公开(公告)号：US20070281092A1
公开(公告)日：2007-12-06
申请号：US11446262
申请日：2006-06-05
申请人： Gerald Fredrickson , Lan Pham , Marlene Schwarz , Todd Robida
发明人： Gerald Fredrickson , Lan Pham , Marlene Schwarz , Todd Robida
IPC分类号： A61L33/00 , B05D1/32
CPC分类号： B05D3/042 , A61L2420/02 , B05B5/082 , B05B12/18 , B05B13/02 , B05B13/0228 , B05B14/00 , B05D1/002 , B05D1/04
摘要： The present invention is directed to methods, processes, and systems for coating portions of a workpiece as well as to workpieces that have themselves been coated in accord with the invention. Under these methods and processes of the invention, a means to repel may be positioned on a mandrel prior to applying a coating to the workpiece. The means to repel may prevent the coating of a target surface of the workpiece.
摘要翻译：本发明涉及用于涂覆工件的部分以及本身已经根据本发明进行了涂覆的工件的方法，工艺和系统。在本发明的这些方法和方法下，在将涂层施加到工件之前，排斥装置可以定位在心轴上。排斥的方法可以防止工件的目标表面的涂覆。

5. 发明申请

US20120160408A1 Composite ePTFE- Silicone Covering for Stent 有权
标题翻译：复合ePTFE-硅胶覆盖用于支架
公开(公告)号：US20120160408A1
公开(公告)日：2012-06-28
申请号：US13335637
申请日：2011-12-22
申请人： Claude Clerc , Gerald Fredrickson , Ralph J. Barry , Paul Norton , Kurt Geitz , Mike Madden
发明人： Claude Clerc , Gerald Fredrickson , Ralph J. Barry , Paul Norton , Kurt Geitz , Mike Madden
IPC分类号： B32B38/08 , A61L33/00
CPC分类号： B29C69/00 , A61L31/10 , B29C41/085 , B29C70/70 , B29K2021/00 , B29K2083/00 , B29K2627/18 , B29L2031/753 , B29L2031/758 , C08L27/18 , C08L83/04
摘要： A medical device consists of a stent having a first surface and a second surface parallel to the first surface; a single expanded polytetrafluoroethylene (ePTFE) layer contacting the first surface of the stent; and an elastomeric layer applied to at least one surface of the stent. In at least one embodiment, the elastomeric layer is silicone. In at least one embodiment, the medical device is manufactured by positioning the ePTFE layer such that a first surface of the ePTFE layer contacts a first surface of the stent to form a stent-ePTFE assembly; and applying an elastomeric solution to the first surface of the ePTFE layer and at least one surface of the stent.
摘要翻译：医疗装置由具有平行于第一表面的第一表面和第二表面的支架构成; 与支架的第一表面接触的单个膨胀聚四氟乙烯（ePTFE）层; 以及应用于支架的至少一个表面的弹性体层。在至少一个实施方案中，弹性体层是有机硅。在至少一个实施例中，通过定位ePTFE层使得ePTFE层的第一表面接触支架的第一表面以形成支架ePTFE组件来制造医疗装置; 以及将弹性体溶液施加到所述ePTFE层的第一表面和所述支架的至少一个表面。

6. 发明授权

US07060319B2 method for using an ultrasonic nozzle to coat a medical appliance 有权
标题翻译：使用超声波喷嘴涂覆医疗器具的方法
公开(公告)号：US07060319B2
公开(公告)日：2006-06-13
申请号：US10670819
申请日：2003-09-24
申请人： Gerald Fredrickson
发明人： Gerald Fredrickson
IPC分类号： B05D1/02 , A61L27/00
CPC分类号： B05B13/025 , A61L31/10 , A61L31/16 , A61L2300/00 , B05B7/0012 , B05B17/06 , B05D1/02 , B05D1/22
摘要： A method for coating a medical appliance includes suspending the medical appliance with a fluidizing gas flow and directing a coating onto an ultrasonic nozzle. The ultrasonic nozzle is directed towards the medical appliance. The method also includes vibrating the ultrasonic nozzle at a rate sufficient to atomize the coating. A device for coating a medical appliance includes a fluidizing gas source adapted to suspend the medical appliance in a suspension area and an ultrasonic nozzle directed at the suspension area and adapted to vibrate. The device also includes a coating source adapted to direct coating onto the ultrasonic nozzle. A medical appliance is provided which has a coating applied by the method.
摘要翻译：一种用于涂覆医疗器具的方法包括：使医疗器具具有流化气体流动并将涂层引导到超声波喷嘴上。超声波喷嘴指向医疗器具。该方法还包括以足以雾化涂层的速率振动超声波喷嘴。用于涂覆医疗器具的装置包括适于将医疗器具悬挂在悬挂区域中的流化气体源和指向悬挂区域并适于振动的超声波喷嘴。该装置还包括适于将涂层引导到超声波喷嘴上的涂层源。提供一种具有通过该方法施加的涂层的医疗器具。

7. 发明授权

US08974622B2 Composite ePTFE-silicone covering for stent 有权
标题翻译：复合ePTFE硅胶覆盖支架
公开(公告)号：US08974622B2
公开(公告)日：2015-03-10
申请号：US13335637
申请日：2011-12-22
申请人： Claude Clerc , Gerald Fredrickson , Ralph Barry , Paul Norton , Kurt Geitz , Mike Madden
发明人： Claude Clerc , Gerald Fredrickson , Ralph Barry , Paul Norton , Kurt Geitz , Mike Madden
IPC分类号： B32B38/08 , A61L31/10 , B29C41/08 , B29C70/70 , B29K83/00 , B29K627/18 , B29L31/00
CPC分类号： B29C69/00 , A61L31/10 , B29C41/085 , B29C70/70 , B29K2021/00 , B29K2083/00 , B29K2627/18 , B29L2031/753 , B29L2031/758 , C08L27/18 , C08L83/04
摘要： A medical device consists of a stent having a first surface and a second surface parallel to the first surface; a single expanded polytetrafluoroethylene (ePTFE) layer contacting the first surface of the stent; and an elastomeric layer applied to at least one surface of the stent. In at least one embodiment, the elastomeric layer is silicone. In at least one embodiment, the medical device is manufactured by positioning the ePTFE layer such that a first surface of the ePTFE layer contacts a first surface of the stent to form a stent-ePTFE assembly; and applying an elastomeric solution to the first surface of the ePTFE layer and at least one surface of the stent.
摘要翻译：医疗装置由具有平行于第一表面的第一表面和第二表面的支架构成; 与支架的第一表面接触的单个膨胀聚四氟乙烯（ePTFE）层; 以及应用于支架的至少一个表面的弹性体层。在至少一个实施方案中，弹性体层是有机硅。在至少一个实施例中，通过定位ePTFE层使得ePTFE层的第一表面接触支架的第一表面以形成支架ePTFE组件来制造医疗装置; 以及将弹性体溶液施加到所述ePTFE层的第一表面和所述支架的至少一个表面。

8. 发明申请

US20070231457A1 Method for spray coating a medical device using a micronozzle 有权
标题翻译：使用微喷嘴喷涂医疗器械的方法
公开(公告)号：US20070231457A1
公开(公告)日：2007-10-04
申请号：US11390179
申请日：2006-03-28
申请人： Lan Pham , Gerald Fredrickson
发明人： Lan Pham , Gerald Fredrickson
IPC分类号： A61L33/00 , B05D1/02
CPC分类号： B05B1/3421 , B05B7/0441 , B05B7/066 , B05D1/02
摘要： The present invention provides for a method for spray application of a coating material onto a medical device by spraying coating material from a micronozzle fabricated from a plurality of sheets that are etched with holes or openings. The openings are aligned to form fluid channels and the sheets are fused together in a planar fashion to define a micronozzle. In another embodiment, the invention provides for a method for spray application of a coating material onto a medical device using micronozzles fabricated in batches by a simplified manufacturing process. In other embodiments, the invention provides for a method for spray application of a coating material onto a medical device by spraying coating material from a micronozzle that includes a swirl or gas-assist atomizer.
摘要翻译：本发明提供了一种通过从由孔或开口蚀刻的多个片材制成的微型喷嘴喷涂涂层材料来将涂层材料喷涂到医疗装置上的方法。开口对准以形成流体通道，并且片材以平面方式熔合在一起以限定微喷嘴。在另一个实施方案中，本发明提供了一种使用通过简化的制造过程分批制造的微喷嘴将涂料施用到医疗装置上的方法。在其它实施例中，本发明提供了一种通过从包括旋流或气体辅助雾化器的微喷嘴喷涂涂层材料来将涂层材料喷涂到医疗装置上的方法。

9. 发明授权

US07758908B2 Method for spray coating a medical device using a micronozzle 有权
标题翻译：使用微喷嘴喷涂医疗器械的方法
公开(公告)号：US07758908B2
公开(公告)日：2010-07-20
申请号：US11390179
申请日：2006-03-28
申请人： Lan Pham , Gerald Fredrickson
发明人： Lan Pham , Gerald Fredrickson
IPC分类号： B05D1/02 , B05B7/10
CPC分类号： B05B1/3421 , B05B7/0441 , B05B7/066 , B05D1/02
摘要： The present invention provides for a method for spray application of a coating material onto a medical device by spraying coating material from a micronozzle fabricated from a plurality of sheets that are etched with holes or openings. The openings are aligned to form fluid channels and the sheets are fused together in a planar fashion to define a micronozzle. In another embodiment, the invention provides for a method for spray application of a coating material onto a medical device using micronozzles fabricated in batches by a simplified manufacturing process. In other embodiments, the invention provides for a method for spray application of a coating material onto a medical device by spraying coating material from a micronozzle that includes a swirl or gas-assist atomizer.
摘要翻译：本发明提供了一种通过从由孔或开口蚀刻的多个片材制成的微型喷嘴喷涂涂层材料来将涂层材料喷涂到医疗装置上的方法。开口对准以形成流体通道，并且片材以平面方式熔合在一起以限定微喷嘴。在另一个实施方案中，本发明提供了一种使用通过简化的制造过程分批制造的微喷嘴将涂料施用到医疗装置上的方法。在其它实施例中，本发明提供了一种通过从包括旋流或气体辅助雾化器的微喷嘴喷涂涂层材料来将涂层材料喷涂到医疗装置上的方法。

10. 发明申请

US20070254091A1 System and method for electrostatic-assisted spray coating of a medical device 审中-公开
标题翻译：医疗器械静电辅助喷涂的系统和方法
公开(公告)号：US20070254091A1
公开(公告)日：2007-11-01
申请号：US11412774
申请日：2006-04-28
申请人： Gerald Fredrickson , Lan Pham , James Feng , Narin Anderson , Tom Eidenschink , Tim O'Connor
发明人： Gerald Fredrickson , Lan Pham , James Feng , Narin Anderson , Tom Eidenschink , Tim O'Connor
IPC分类号： A61L33/00 , B05D1/02 , B05B5/025
CPC分类号： B05B5/035 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/606 , A61L2420/02 , B05B1/3415 , B05B5/0407 , B05B5/08 , B05B7/0433 , B05D1/04
摘要： A system and method for the electrostatic spray application of a coating material onto a medical device. The coating material is electrically charged and an atomizer is used to atomize the coating material, creating electrically charged droplets which coat the medical device. In alternate embodiments, a swirl atomizer, a pressure atomizer, an ultrasound atomizer, a rotary atomizer, and an effervescent atomizer are used to atomize the coating material.
摘要翻译：一种用于将涂层材料静电喷涂到医疗装置上的系统和方法。涂覆材料带电，并且使用雾化器来雾化涂层材料，产生涂覆医疗装置的带电液滴。在替代实施例中，使用旋流雾化器，压力雾化器，超声雾化器，旋转雾化器和泡腾雾化器来雾化涂层材料。

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