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1. 发明授权

US08224445B2 Far-field sensing channel for implantable cardiac device 有权
标题翻译：用于可植入心脏装置的远场感测通道
公开(公告)号：US08224445B2
公开(公告)日：2012-07-17
申请号：US13205387
申请日：2011-08-08
申请人： Geng Zhang , Douglas R. Daum , James O. Gilkerson , Quan Ni
发明人： Geng Zhang , Douglas R. Daum , James O. Gilkerson , Quan Ni
IPC分类号： A61N1/37
CPC分类号： A61N1/371 , A61N1/3621 , A61N1/3756
摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.
摘要翻译：植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

2. 发明授权

US07996083B2 Far-field sensing channel for implantable cardiac device 有权
标题翻译：用于可植入心脏装置的远场感测通道
公开(公告)号：US07996083B2
公开(公告)日：2011-08-09
申请号：US10858848
申请日：2004-06-02
申请人： Geng Zhang , Douglas R. Daum , James O. Gilkerson , Quan Ni
发明人： Geng Zhang , Douglas R. Daum , James O. Gilkerson , Quan Ni
IPC分类号： A61N1/368
CPC分类号： A61N1/371 , A61N1/3621 , A61N1/3756
摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.
摘要翻译：植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

3. 发明申请

US20110295136A1 FAR-FIELD SENSING CHANNEL FOR IMPLANTABLE CARDIAC DEVICE 有权
标题翻译：用于可植入心脏装置的前置感测通道
公开(公告)号：US20110295136A1
公开(公告)日：2011-12-01
申请号：US13205387
申请日：2011-08-08
申请人： Greg Zhang , Douglas R. Daum , James O. Gilkerson , Quan Ni
发明人： Greg Zhang , Douglas R. Daum , James O. Gilkerson , Quan Ni
IPC分类号： A61N1/365 , A61B5/0452 , A61N1/37
CPC分类号： A61N1/371 , A61N1/3621 , A61N1/3756
摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.
摘要翻译：植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

4. 发明授权

US08639331B2 Systems and methods for providing arrhythmia therapy in MRI environments 有权
标题翻译：在MRI环境中提供心律失常治疗的系统和方法
公开(公告)号：US08639331B2
公开(公告)日：2014-01-28
申请号：US12639848
申请日：2009-12-16
申请人： Scott R. Stubbs , James O. Gilkerson , Diane Schuster
发明人： Scott R. Stubbs , James O. Gilkerson , Diane Schuster
IPC分类号： A61N1/00
CPC分类号： A61N1/3931 , A61N1/3688 , A61N1/37 , A61N1/3718
摘要： Systems and methods for arrhythmia therapy in MRI environments are disclosed. Various systems disclosed utilize ATP therapy rather than ventricular shocks when patients are subjected to electromagnetic fields in an MRI scanner bore and shock therapy is not available. As the patient is moved out from within the scanner bore and away from the MRI scanner, the magnetic fields diminish in strength eventually allowing a high voltage capacitor within the IMD to charge if necessary. The system may detect when the electromagnetic fields no longer interfere with the shock therapy and will transition the IMD back to a normal operational mode where shock therapy can be delivered. Then, if the arrhythmia still exists, the system will carry out all of the system's prescribed operations, including the delivery of electric shocks to treat the arrhythmia.
摘要翻译：公开了MRI环境中心律失常治疗的系统和方法。所公开的各种系统利用ATP治疗而不是心室休克，当患者在MRI扫描器孔中经受电磁场并且不能使用休克疗法时。当患者从扫描仪孔内移出并远离MRI扫描仪时，磁场的强度减弱，最终允许IMD内的高电压电容器根据需要进行充电。该系统可以检测何时电磁场不再干扰休克疗法，并将IMD转移回正常的操作模式，其中可以进行休克疗法。那么，如果心律失常仍然存在，系统将执行系统的所有规定的操作，包括交付电击治疗心律失常。

5. 发明授权

US08306619B2 Apparatus and method for treating ventricular tachyarrhythmias 有权
标题翻译：用于治疗室性快速性心律失常的装置和方法
公开(公告)号：US08306619B2
公开(公告)日：2012-11-06
申请号：US13246400
申请日：2011-09-27
申请人： David B. Krig , James O. Gilkerson , Robert D. Dreher , Jan D. Wald , William J. Linder , William L. Zimmer
发明人： David B. Krig , James O. Gilkerson , Robert D. Dreher , Jan D. Wald , William J. Linder , William L. Zimmer
IPC分类号： A61N1/362
CPC分类号： A61N1/3622 , A61N1/395 , A61N1/3962
摘要： A system and method for selectively treating a ventricular tachycardia based on sensed atrial and ventricular intervals from the patient's heart. A detection window of the ten most recent atrial and ventricular intervals are analyzed for the occurrence of either tachycardia or fibrillation. When a majority of the sensed intervals are satisfied, the apparatus starts a duration time interval. Ventricular intervals and atrial intervals are compare, ventricular interval greater than the atrial interval by a bias factor the system delivers tachycardia therapy to the heart. Alternatively, the method withholds tachycardia therapy to the heart when the atrial rate is classified as atrial fibrillation and the ventricular response is unstable.
摘要翻译：一种系统和方法，用于根据来自患者心脏的感觉的心房和心室间隔选择性地治疗室性心动过速。分析十个最近的心房和心室间隔的检测窗口，用于心动过速或颤动的发生。当满足感测间隔的大部分时，设备开始持续时间间隔。比较心室间隔和心房间隔，心室间隔大于心房间隔，系统将心动过速治疗提供给心脏。或者，当心房率被分类为心房颤动和心室反应不稳定时，该方法禁止对心脏的心动过速治疗。

6. 发明授权

US08271083B2 System for managing refractory periods in a cardiac rhythm management device with biventricular sensing 有权
$System for managing refractory periods in a cardiac rhythm management device with biventricular sensing$
标题翻译：用于管理具有双心室感知的心律管理装置中的不良期的系统
公开(公告)号：US08271083B2
公开(公告)日：2012-09-18
申请号：US12254615
申请日：2008-10-20
申请人： Jeffrey E. Stahmann , Andrew P. Kramer , James O. Gilkerson , Lorenzo DiCarlo , Rene H. Wentkowski
发明人： Jeffrey E. Stahmann , Andrew P. Kramer , James O. Gilkerson , Lorenzo DiCarlo , Rene H. Wentkowski
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A method and system for managing refractory periods in a cardiac rhythm management device configured for biventricular or biatrial sensing. Refractory periods for each channel of the pacemaker are provided by interval timers that are triggered by sensed or paced events in order to prevent misinterpretation of sensing signals.
摘要翻译：一种用于管理配置用于双心室或双心房感应的心律管理装置中的不应期的方法和系统。起搏器每个通道的耐火时间由间隔定时器提供，由感测或起搏事件触发，以防止感测信号的误解。

7. 发明授权

US08068909B2 Measurement of cardiac performance with movement sensors and related methods 失效
标题翻译：使用运动传感器和相关方法测量心脏性能
公开(公告)号：US08068909B2
公开(公告)日：2011-11-29
申请号：US11769402
申请日：2007-06-27
申请人： Bin Mi , Yongxing Zhang , Yunlong Zhang , James O. Gilkerson
发明人： Bin Mi , Yongxing Zhang , Yunlong Zhang , James O. Gilkerson
IPC分类号： A61B5/02
CPC分类号： A61N1/056 , A61B5/02438 , A61B5/02444 , A61B5/6846 , A61B5/6851 , A61N1/36514 , A61N1/36578
摘要： Embodiments of the invention are related to implantable devices including movement sensors and related methods for measuring cardiac performance, amongst other things. In an embodiment, the invention includes an implantable electrical stimulation lead. The electrical stimulation lead can include a lead body having a proximal end and a distal end and a sheath defining a central lumen. The lead body can further include an electrical conductor disposed within the central lumen of the sheath. The stimulation lead can further include a stimulation electrode positioned at the distal end of the lead body, the stimulation electrode in electrical communication with the electrical conductor. The electrical stimulation lead can include an flexion sensor coupled to the lead body, the movement sensor configured to generate a signal in response to movement of the lead body. In an embodiment, the invention includes a method of monitoring the condition of a heart failure patient. In an embodiment, the invention includes a method of treating unstable arrhythmia in a patient. Other embodiments are also included herein.
摘要翻译：本发明的实施例涉及包括运动传感器和用于测量心脏性能的相关方法的可植入装置。在一个实施例中，本发明包括可植入电刺激引线。电刺激引线可以包括具有近端和远端的引线主体和限定中心内腔的护套。引线体还可以包括设置在护套的中心腔内的电导体。刺激引线还可以包括位于引线体的远端处的刺激电极，该刺激电极与电导体电连通。电刺激引线可以包括耦合到引线主体的屈曲传感器，所述运动传感器被配置为响应于引线主体的移动而产生信号。在一个实施例中，本发明包括监测心力衰竭患者状况的方法。在一个实施方案中，本发明包括治疗患者不稳定性心律失常的方法。本文还包括其它实施例。

8. 发明授权

US08046071B2 Pacemaker passive measurement testing system 有权
标题翻译：起搏器被动测量测试系统
公开(公告)号：US08046071B2
公开(公告)日：2011-10-25
申请号：US12765486
申请日：2010-04-22
申请人： Vickie L. Conley , James O. Gilkerson , David L. Perschbacher
发明人： Vickie L. Conley , James O. Gilkerson , David L. Perschbacher
IPC分类号： A61N1/362
CPC分类号： A61N1/3706 , A61N1/3702
摘要： A system and method for passively testing a cardiac pacemaker in which sensing signal amplitudes and lead impedance values are measured and stored while the pacemaker is functioning in its programmed mode. The amplitude and impedance data may be gotten and stored periodically at regular intervals to generate a historical record for diagnostic purposes. Sensing signal amplitudes may also be measured and stored from a sensing channel which is currently not programmed to be active as long as the pacemaker is physically configured to support the sensing channel. Such data can be useful in evaluating whether a switch in the pacemaker's operating mode is desirable.
摘要翻译：一种用于被动测试心脏起搏器的系统和方法，其中在起搏器在其编程模式下起作用时测量和存储感测信号幅度和引线阻抗值。可以以规律的间隔周期性获得和存储振幅和阻抗数据，以产生用于诊断目的的历史记录。只要心脏起搏器物理配置为支持感测通道，感测信号幅度也可以从目前未编程为有效的感测通道测量和存储。这样的数据可用于评估起搏器的操作模式中的开关是否可取。

9. 发明授权

US07970463B2 Anti-tachyarrhythmia system with unified atrial tachyarrhythmia rate threshold 有权
标题翻译：抗心律失常系统具有统一的房性心律失常率阈值
公开(公告)号：US07970463B2
公开(公告)日：2011-06-28
申请号：US12264778
申请日：2008-11-04
申请人： David L. Perschbacher , James O. Gilkerson , James Kalgren
发明人： David L. Perschbacher , James O. Gilkerson , James Kalgren
IPC分类号： A61N1/00 , A61B5/04
CPC分类号： A61N1/3621 , A61N1/3624 , A61N1/37247 , A61N1/395
摘要： A cardiac rhythm management (CRM) system includes an implantable cardioverter defibrillator (ICD) and an external system. The ICD includes a plurality of functional modules performing tachyarrhythmia classification and therapy control functions using atrial tachyarrhythmia rate thresholds that are set to a unified value. In one embodiment, the CRM system allows a user to activate and deactivate each of the functional modules and program the unified value using the external system.
摘要翻译：心律管理（CRM）系统包括植入式心律转复除颤器（ICD）和外部系统。 ICD包括多个功能模块，其使用被设置为统一值的心房快速性心律失常率阈值来执行快速性心律失常分类和治疗控制功能。在一个实施例中，CRM系统允许用户激活和停用每个功能模块，并使用外部系统对统一值进行编程。

10. 发明授权

US07966069B2 Medical device interface system with automatic rate threshold adjustment 有权
标题翻译：医疗设备接口系统具有自动速率阈值调整功能
公开(公告)号：US07966069B2
公开(公告)日：2011-06-21
申请号：US11856558
申请日：2007-09-17
申请人： Les Norman Peterson , Paula Dieterle , Par Lindh , James Kalgren , James O. Gilkerson , Allan T. Koshiol , Tala L Bynum , David Callahan
发明人： Les Norman Peterson , Paula Dieterle , Par Lindh , James Kalgren , James O. Gilkerson , Allan T. Koshiol , Tala L Bynum , David Callahan
IPC分类号： A61N1/02
CPC分类号： A61N1/37247 , A61N1/3993 , G06F19/00 , Y10S128/903
摘要： An external programming system and method for implantable medical devices (IMDs) is disclosed. The external programming system includes a communication circuit, a display device, an input device, and a processor. The communication circuit is configured to link to an IMD to transmit or monitor IMD timing parameter settings. The display device is configured to display a textual representation of an IMD timing parameter setting and a specified IMD timing parameter limit, a graphical slide control comprising a movable feature indicating the IMD timing parameter setting, a graphical slide-control limit corresponding to the specified IMD timing parameter limit, and a graphical representation of physiologic information including a portion of said graphical representation aligned with the slide control movable feature. The input device is configured to adjust the movable feature in response to user input. The processor is configured to monitor or store an IMD timing parameter setting.
摘要翻译：公开了用于可植入医疗装置（IMD）的外部编程系统和方法。外部编程系统包括通信电路，显示设备，输入设备和处理器。通信电路被配置为链接到IMD以发送或监视IMD定时参数设置。显示装置被配置为显示IMD定时参数设置和指定的IMD定时参数限制的文本表示，包括指示IMD定时参数设置的可移动特征的图形幻灯片控制，对应于指定IMD的图形幻灯片控制限制定时参数限制，以及包括与滑动控制可移动特征对齐的所述图形表示的一部分的生理信息的图形表示。输入设备被配置为响应于用户输入来调整可移动特征。处理器配置为监视或存储IMD定时参数设置。

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