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1. 发明授权

US06495051B1 Methods for preparing blood or plasma component solutions with improved concentrations 失效
标题翻译：用于制备浓度提高的血液或血浆成分溶液的方法
公开(公告)号：US06495051B1
公开(公告)日：2002-12-17
申请号：US09677094
申请日：2000-09-29
申请人： Gautom Bhaskar , Glenn Jorgensen
发明人： Gautom Bhaskar , Glenn Jorgensen
IPC分类号： A01N102
CPC分类号： B01D21/262 , A61M1/3693 , A61M2202/0449 , A61M2202/045 , B01D2221/10 , B04B2005/0485
摘要： A method for separating a blood component, e.g., fibrin monomer, from blood or plasma. The method utilizes a container with a reaction chamber for receiving the plasma. The reaction chamber is defined by a wall and an agent is supplied to the reaction chamber for converting the fibrinogen content of the plasma into a non-cross-linked fibrin polymer. The method also utilizes a device for centrifuging the reaction chamber with the plasma and the agent to a degree sufficient for separating the non-cross-linked fibrin polymer from the plasma, for depositing the polymer on the outer wall of the reaction chamber, and for expelling the remaining plasma from the reaction chamber. A solvent is supplied to the reaction chamber for dissolving the non-cross-linked fibrin polymer. The solvent is supplied to the reaction chamber in a first amount for dissolving the non-cross-linked fibrin polymer which is less than the total amount of solvent for dissolving the polymer. The remaining solvent is supplied to the reaction chamber in one or more portions to flush the reaction chamber and other portions of the device and recover additional non-cross-linked fibrin polymer.
摘要翻译：一种将血液成分例如纤维蛋白单体与血液或血浆分离的方法。该方法利用具有用于接收等离子体的反应室的容器。反应室由壁限定，并且将试剂供应到反应室以将血浆的纤维蛋白原含量转化为非交联的纤维蛋白聚合物。该方法还利用了用等离子体和试剂将反应室离心至足以将非交联的纤维蛋白聚合物与等离子体分离的程度的装置，用于将聚合物沉积在反应室的外壁上，从反应室排出剩余的等离子体。将溶剂供应到反应室以溶解非交联的纤维蛋白聚合物。将溶剂以第一量供给反应室，以溶解小于溶解聚合物的溶剂的总量的非交联纤维蛋白聚合物。将剩余的溶剂以一个或多个部分供应到反应室中以冲洗反应室和该装置的其它部分，并回收另外的非交联的纤维蛋白聚合物。

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