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1. 发明授权

US07757924B2 Single fold system for tissue approximation and fixation 有权
标题翻译：用于组织近似和固定的单折系统
公开(公告)号：US07757924B2
公开(公告)日：2010-07-20
申请号：US11529201
申请日：2006-09-28
申请人： Craig Gerbi , Gary Weller , Jamy Gannoe , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
发明人： Craig Gerbi , Gary Weller , Jamy Gannoe , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
IPC分类号： A61B17/04
CPC分类号： A61B17/29 , A61B17/07207 , A61B2017/07214 , A61B2017/081 , A61B2017/2905 , A61B2017/306
摘要： A single fold system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create at least one fold within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate a single fold of tissue from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device and to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
摘要翻译：本文描述了用于组织近似和固定的单折叠系统。装置以微创方式在患者体内推进，以在中空身体器官内产生至少一个折叠。该系统包括组织采集和折叠装置和组织缝合或固定装置，每个组合装订或固定装置一起用作系统。采集装置用于从中空体器官内部近似组织的单一折叠，并且缝合装置前进穿过通过采集装置限定的主腔，并用于固定组织。锁定装置被锁定以相对于采集装置保持其旋转方向，并提供用户装订装置的位置信息。采集装置还被配置为在缝合装置被夹持到组织之前为吻合装置提供侧向稳定性。

2. 发明授权

US08590761B2 Single fold system for tissue approximation and fixation 有权
标题翻译：用于组织近似和固定的单折系统
公开(公告)号：US08590761B2
公开(公告)日：2013-11-26
申请号：US11716157
申请日：2007-03-09
申请人： Craig Gerbi , Gary Weller , Jamy Gannoe , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
发明人： Craig Gerbi , Gary Weller , Jamy Gannoe , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
IPC分类号： A61B17/04 , A61B17/10 , B31B1/00
CPC分类号： A61B17/29 , A61B17/07207 , A61B2017/07214 , A61B2017/081 , A61B2017/2905 , A61B2017/306
摘要： A single fold system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create at least one fold within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate a single fold of tissue from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device and to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
摘要翻译：本文描述了用于组织近似和固定的单折叠系统。装置以微创方式在患者体内推进，以在中空身体器官内产生至少一个折叠。该系统包括组织采集和折叠装置和组织缝合或固定装置，每个组合装订或固定装置一起用作系统。采集装置用于从中空体器官内部近似组织的单一折叠，并且缝合装置前进穿过通过采集装置限定的主腔，并用于固定组织。锁定装置被锁定以相对于采集装置保持其旋转方向，并提供用户装订装置的位置信息。采集装置还被配置为在缝合装置被夹持到组织之前为吻合装置提供侧向稳定性。

3. 发明授权

US08007505B2 System for tissue approximation and fixation 有权
标题翻译：组织近似和固定系统
公开(公告)号：US08007505B2
公开(公告)日：2011-08-30
申请号：US11499349
申请日：2006-08-03
申请人： Gary Weller , Jamy Gannoe , Craig Gerbi , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
发明人： Gary Weller , Jamy Gannoe , Craig Gerbi , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
IPC分类号： A61B17/08 , A61B17/10 , A61B17/04
CPC分类号： A61B17/29 , A61B17/07207 , A61B17/1114 , A61B2017/00323 , A61B2017/00353 , A61B2017/00946 , A61B2017/07214 , A61B2017/1103 , A61B2017/2905 , A61B2017/306
摘要： A system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate tissue regions from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the approximated tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device as well as to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
摘要翻译：本文描述了用于组织近似和固定的系统。这些装置在患者体内以微创方式前进，以在中空身体器官内产生一个或多个分裂或症状。该系统包括组织采集和折叠装置和组织缝合或固定装置，每个组合装订或固定装置一起用作系统。采集装置用于从中空体器官内部近似组织区域，并且缝合装置前进穿过通过采集装置限定的主腔，并用于固定近似组织。锁定装置被锁定以相对于采集装置保持其旋转定向，并且提供用户装订装置的位置信息。采集装置还被配置为在缝合装置被夹持到组织之前为吻合装置提供侧向稳定性。

4. 发明授权

US07097650B2 System for tissue approximation and fixation 有权
标题翻译：组织近似和固定系统
公开(公告)号：US07097650B2
公开(公告)日：2006-08-29
申请号：US10686326
申请日：2003-10-14
申请人： Gary Weller , Jamy Gannoe , Craig Gerbi , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
发明人： Gary Weller , Jamy Gannoe , Craig Gerbi , Douglas S. Sutton , Andrew H. Hancock , Gilbert Mata, Jr.
IPC分类号： A61B17/08
CPC分类号： A61B17/29 , A61B17/07207 , A61B17/1114 , A61B2017/00323 , A61B2017/00353 , A61B2017/00946 , A61B2017/07214 , A61B2017/1103 , A61B2017/2905 , A61B2017/306
摘要： A system for tissue approximation and fixation is described herein. The devices are advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a tissue acquisition and folding device and a tissue stapling or fixation device, each of which is used together as a system. The acquisition device is used to approximate tissue regions from within the hollow body organ and the stapling device is advanced through a main lumen defined through the acquisition device and is used to affix the approximated tissue. The stapling device is keyed to maintain its rotational orientation relative to the acquisition device as well as to provide the user positional information of the stapling device. The acquisition device is also configured to provide lateral stability to the stapling device prior to the stapling device being clamped onto tissue.
摘要翻译：本文描述了用于组织近似和固定的系统。这些装置在患者体内以微创方式前进，以在中空身体器官内产生一个或多个分裂或症状。该系统包括组织采集和折叠装置和组织缝合或固定装置，每个组合装订或固定装置一起用作系统。采集装置用于从中空体器官内部近似组织区域，并且缝合装置前进穿过通过采集装置限定的主腔，并用于固定近似组织。锁定装置被锁定以相对于采集装置保持其旋转定向，并且提供用户装订装置的位置信息。采集装置还被配置为在缝合装置被夹持到组织之前为吻合装置提供侧向稳定性。

5. 发明授权

US06773440B2 Method and device for use in tissue approximation and fixation 有权
公开(公告)号：US06773440B2
公开(公告)日：2004-08-10
申请号：US10188547
申请日：2002-07-02
申请人： Jamy Gannoe , Gary Weller , Craig Gerbi , Douglas S. Sutton , Gilbert Mata, Jr. , J. Stephen Scott
发明人： Jamy Gannoe , Gary Weller , Craig Gerbi , Douglas S. Sutton , Gilbert Mata, Jr. , J. Stephen Scott
IPC分类号： A61B1708
CPC分类号： A61F5/0086 , A61B17/00234 , A61B17/064 , A61B17/0643 , A61B17/068 , A61B17/29 , A61B17/30 , A61B2017/00561 , A61B2017/00827 , A61B2017/0647 , A61B2017/081 , A61B2017/2929 , A61B2017/2944 , A61B2017/306
摘要： Methods and devices for use in tissue approximation and fixation are described herein. The present invention provides, in part, methods and devices for acquiring tissue folds from the anterior and posterior portions of a hollow body organ, e.g., a stomach, positioning the tissue folds for affixing within a fixation zone of the stomach, preferably to create a pouch or partition below the esophagus, and fastening the tissue folds such that a tissue bridge forms excluding the pouch from the greater stomach cavity. The present invention further provides devices for performing a transoral, endoscopic hollow organ division, including a tissue acquisition device capable of acquiring the desired tissue, a tensioning device for positioning the acquired tissue, and a fastening element to secure the outer layers of the acquired tissue such that the desired healing response is achieved.

6. 发明授权

US08062207B2 Intra-gastric fastening devices 有权
标题翻译：胃内紧固装置
公开(公告)号：US08062207B2
公开(公告)日：2011-11-22
申请号：US11129626
申请日：2005-05-13
申请人： Jamy Gannoe , Gary Weller , Craig Gerbi , Douglas S. Sutton
发明人： Jamy Gannoe , Gary Weller , Craig Gerbi , Douglas S. Sutton
IPC分类号： A61F2/00
CPC分类号： A61F5/003 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/0644 , A61B17/08 , A61B2017/00557 , A61B2017/0441 , A61B2017/06171 , A61B2017/0649 , A61F5/0036
摘要： Intra-gastric fastening devices are disclosed herein. Expandable devices that are inserted into the stomach of the patient are maintained within by anchoring or otherwise fixing the expandable devices to the stomach walls. Such expandable devices, like inflatable balloons, have tethering regions for attachment to the one or more fasteners which can be configured to extend at least partially through one or several folds of the patient's stomach wall. The fasteners are thus affixed to the stomach walls by deploying the fasteners and manipulating the tissue walls entirely from the inside organ. Such fasteners can be formed in a variety of configurations, e.g., helical, elongate, ring, clamp, and they can be configured to be non-piercing. Alternatively, sutures can be used to wrap around or through a tissue fold for tethering the expandable devices. Non-piercing biased clamps can also be used to tether the device within the stomach.
摘要翻译：本文公开了胃内紧固装置。通过锚定或以其他方式将可扩张装置固定在胃壁上，可以将插入到患者胃中的可扩张装置保持在内部。这种可膨胀装置，如可充气气囊，具有用于连接到一个或多个紧固件的束缚区域，所述紧固件可构造成至少部分延伸穿过患者胃壁的一个或多个折叠。因此，紧固件通过展开紧固件并完全从内部器官操纵组织壁而固定在胃壁上。这种紧固件可以以各种构造形成，例如螺旋，细长，环形，夹紧，并且它们可被构造成不穿孔。或者，可以使用缝合线缠绕或穿过组织折叠以将可扩张装置系在一起。非刺穿偏压夹具也可用于将装置系在胃内。

7. 发明授权

US09028511B2 Devices and methods for placement of partitions within a hollow body organ 有权
标题翻译：在空心体器官中放置隔板的装置和方法
公开(公告)号：US09028511B2
公开(公告)日：2015-05-12
申请号：US10797439
申请日：2004-03-09
申请人： Gary Weller , Alex T. Roth , Christopher Julian , Jamy Gannoe , Andrew H. Hancock , Craig Gerbi
发明人： Gary Weller , Alex T. Roth , Christopher Julian , Jamy Gannoe , Andrew H. Hancock , Craig Gerbi
IPC分类号： A61B17/08 , A61B17/072 , A61F5/00 , A61B17/00 , A61B17/30
CPC分类号： A61B17/072 , A61B17/07207 , A61B2017/003 , A61B2017/07214 , A61B2017/306 , A61F5/0083
摘要： Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
摘要翻译：描述用于组织采集和固定或胃成形术的装置和方法。通常，系统的装置可以在患者体内以微创方式进行，例如经由内窥镜，经皮等进行，从而在空心体器官内产生一个或多个分裂或or肿。这样的分裂或痉挛可以在器官内形成限制性障碍，或者可以放置成小于剩余胃体积的小袋或胃腔，以基本上充当活动性胃，例如由外科手术Roux-En- Y胃旁路手术。此外，该系统被配置为使得一旦完成了由成形术装置获取的组织，对于所获取的组织的任何操纵都是不必要的，因为该装置能够将获取的组织自动配置成所需的构造。

8. 发明授权

US06746460B2 Intra-gastric fastening devices 有权
公开(公告)号：US06746460B2
公开(公告)日：2004-06-08
申请号：US10215070
申请日：2002-08-07
申请人： Jamy Gannoe , Gary Weller , Craig Gerbi , Douglas S. Sutton
发明人： Jamy Gannoe , Gary Weller , Craig Gerbi , Douglas S. Sutton
IPC分类号： A61B1708
CPC分类号： A61F5/003 , A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/0644 , A61B17/08 , A61B2017/00557 , A61B2017/0441 , A61B2017/06171 , A61B2017/0649 , A61F5/0036
摘要： Intra-gastric fastening devices are disclosed herein. Expandable devices that are inserted into the stomach of the patient are maintained within by anchoring or otherwise fixing the expandable devices to the stomach walls. Such expandable devices, like inflatable balloons, have tethering regions for attachment to the one or more fasteners which can be configured to extend at least partially through one or several folds of the patient's stomach wall. The fasteners are thus affixed to the stomach walls by deploying the fasteners and manipulating the tissue walls entirely from the inside of the organ. Such fasteners can be formed in a variety of configurations, e.g., helical, elongate, ring, clamp, and they can be configured to be non-piercing. Alternatively, sutures can be used to wrap around or through a tissue fold for tethering the expandable devices. Non-piercing biased clamps can also be used to tether the device within the stomach.

9. 发明授权

US08628547B2 Devices and methods for placement of partitions within a hollow body organ 有权
标题翻译：在空心体器官中放置隔板的装置和方法
公开(公告)号：US08628547B2
公开(公告)日：2014-01-14
申请号：US10797303
申请日：2004-03-09
申请人： Gary Weller , Alex T. Roth , Christopher Julian , Jamy Gannoe , Andrew H. Hancock , Craig Gerbi
发明人： Gary Weller , Alex T. Roth , Christopher Julian , Jamy Gannoe , Andrew H. Hancock , Craig Gerbi
IPC分类号： A61B17/08
CPC分类号： A61F5/0086 , A61B17/072 , A61B2017/003 , A61B2017/00818 , A61B2017/07214
摘要： Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.
摘要翻译：描述用于组织采集和固定或胃成形术的装置和方法。通常，系统的装置可以在患者体内以微创方式进行，例如经由内窥镜，经皮等进行，从而在空心体器官内产生一个或多个分裂或or肿。这样的分裂或痉挛可以在器官内形成限制性障碍，或者可以放置成小于剩余胃体积的小袋或胃腔，以基本上充当活动性胃，例如由外科手术Roux-En- Y胃旁路手术。此外，该系统被配置为使得一旦完成了由成形术装置获取的组织，对于所获取的组织的任何操纵都是不必要的，因为该装置能够将获取的组织自动配置成所需的构造。

10. 发明授权

US07175638B2 Method and devices for modifying the function of a body organ 有权
公开(公告)号：US07175638B2
公开(公告)日：2007-02-13
申请号：US10417790
申请日：2003-04-16
申请人： Jamy Gannoe , Gary Weller , Douglas S. Sutton , Craig Gerbi
发明人： Jamy Gannoe , Gary Weller , Douglas S. Sutton , Craig Gerbi
IPC分类号： A61B17/08
CPC分类号： A61F5/0086 , A61B17/00234 , A61B17/0469
摘要： Methods and devices for partitioning or plicating a region of a hollow body organ are described herein. These methods and devices relate generally to medical apparatus and methods and more particularly to devices and methods for affecting a change in the function of a hollow body organ, particularly a stomach, intestine or gastrointestinal tract. These changes can include reducing the volume capacity of the hollow body organ, disrupting or altering the normal function of the organ, functionally excluding certain sections of the organ either by affixing adjacent tissue or excising certain regions, or affecting or correcting the response of the organ to naturally occurring stimuli, such as ingestion.

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