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    • 1. 发明申请
    • HEART STIMULATOR
    • 心脏刺激器
    • US20080140146A1
    • 2008-06-12
    • US11567753
    • 2006-12-07
    • Garth GARNERHannes KraetschmerDirk MuessigIndra B. Nigam
    • Garth GARNERHannes KraetschmerDirk MuessigIndra B. Nigam
    • A61N1/362
    • A61N1/3712
    • A heart stimulator provides a reliable automatic capture threshold search feature. A stimulation pulse generator is connected to at least a ventricular stimulation electrode for delivering electric stimulation pulses to at least the ventricle of the heart. The stimulation pulses generated have a strength depending on a control signal. A sensing stage is connected to an electrode for picking up electric potentials inside at least said ventricle of a heart and a control unit connected to the sensing stage and to the stimulation pulse generator determines points of time for scheduling stimulation pulses, to trigger the stimulation pulse generator so as to deliver a stimulation pulse when scheduled and to put out control signals for controlling the strength of the stimulation pulse. The control unit is further adapted to perform a capture analysis which may take into account extraordinary events.
    • 心脏刺激器提供可靠的自动捕获阈值搜索功能。 刺激脉冲发生器连接到至少一个心室刺激电极,用于将电刺激脉冲传送到至少心脏的心室。 产生的刺激脉冲具有取决于控制信号的强度。 感测级连接到用于拾取心脏的至少所述心室内的电位的电极和连接到感测级的控制单元,并且刺激脉冲发生器确定调度刺激脉冲的时间点,以触发刺激脉冲 发生器,以便在调度时传递刺激脉冲,并且输出用于控制刺激脉冲的强度的控制信号。 控制单元还适于执行可以考虑特殊事件的捕获分析。
    • 2. 发明授权
    • Heart stimulator
    • 心脏刺激器
    • US07580748B2
    • 2009-08-25
    • US11567753
    • 2006-12-07
    • Garth GarnerHannes KraetschmerDirk MuessigIndra B. Nigam
    • Garth GarnerHannes KraetschmerDirk MuessigIndra B. Nigam
    • A61N1/00
    • A61N1/3712
    • A heart stimulator provides a reliable automatic capture threshold search feature. A stimulation pulse generator is connected to at least a ventricular stimulation electrode for delivering electric stimulation pulses to at least the ventricle of the heart. The stimulation pulses generated have a strength depending on a control signal. A sensing stage is connected to an electrode for picking up electric potentials inside at least said ventricle of a heart and a control unit connected to the sensing stage and to the stimulation pulse generator determines points of time for scheduling stimulation pulses, to trigger the stimulation pulse generator so as to deliver a stimulation pulse when scheduled and to put out control signals for controlling the strength of the stimulation pulse. The control unit is further adapted to perform a capture analysis which may take into account extraordinary events.
    • 心脏刺激器提供可靠的自动捕获阈值搜索功能。 刺激脉冲发生器连接到至少一个心室刺激电极,用于将电刺激脉冲传送到至少心脏的心室。 产生的刺激脉冲具有取决于控制信号的强度。 感测级连接到用于拾取心脏的至少所述心室内的电位的电极和连接到感测级的控制单元,并且刺激脉冲发生器确定调度刺激脉冲的时间点,以触发刺激脉冲 发生器,以便在调度时传递刺激脉冲,并且输出用于控制刺激脉冲的强度的控制信号。 控制单元还适于执行可以考虑特殊事件的捕获分析。
    • 3. 发明申请
    • DEVICE, METHOD AND COMPUTER-READABLE STORAGE MEDIUM FOR CLASSIFYING ATRIAL TACHYARRHYTHMIA
    • 装置,方法和计算机可读存储介质用于分类ATRTIC TACHYARRHYTHMIA
    • US20100100143A1
    • 2010-04-22
    • US12254728
    • 2008-10-20
    • Indra B. NigamDirk MuessigHannes Kraetschmer
    • Indra B. NigamDirk MuessigHannes Kraetschmer
    • A61N1/39A61N1/365
    • A61N1/3704A61B5/042A61B5/046A61B5/0468A61B5/6846A61N1/395
    • Device for classifying tachyarrhythmia that obtains pre-defined values, monitors atrial intervals and compares lengths of each interval with pre-defined value IL, stores length of atrial interval if length is shorter than IL, in case X of most recent Y number of atrial intervals have length shorter than IL, evaluates most recent =1 criteria, and controls a cardiac device depending on the classification. Atrial intervals are first evaluated by using the “X-out-of-Y” criterion and subsequently checked for stability after an atrial tachyarrhythmia is detected using “X-out-of-Y” criterion. For stability check, only intervals found shorter than the interval limit are used. Check is based on interval-to-interval comparison rather than as generally practiced, comparisons of individual intervals with the minimum or average of all intervals.
    • 用于分类获得预定值的快速性心律失常的装置,监测心房间隔并且将每个间隔的长度与预定义值IL进行比较,如果长度短于IL,则存储心房间隔的长度,在最近的Y个心房间隔的情况下 长度短于IL,评估最近的<= N心房间隔,长度 = 1标准,则将心房快速性心律失常分类为稳定,并根据 分类。 首先通过使用“X-out-Y”标准来评估心房间隔,并随后在使用“X-out-of-Y”标准检测到房性快速性心律失常之后检查其稳定性。 对于稳定性检查,仅使用间隔时间间隔短于间隔限制。 检查是基于间隔间隔比较而不是通常实践的,将各个间隔与所有间隔的最小值或平均值进行比较。
    • 4. 发明授权
    • Device, method and computer-readable storage medium for classifying atrial tachyarrhythmia
    • 用于分类房性快速性心律失常的装置,方法和计算机可读存储介质
    • US08024031B2
    • 2011-09-20
    • US12254728
    • 2008-10-20
    • Indra B. NigamDirk MuessigHannes Kraetschmer
    • Indra B. NigamDirk MuessigHannes Kraetschmer
    • A61B5/04
    • A61N1/3704A61B5/042A61B5/046A61B5/0468A61B5/6846A61N1/395
    • Device for classifying tachyarrhythmia that obtains pre-defined values, monitors atrial intervals and compares lengths of each interval with pre-defined value IL, stores length of atrial interval if length is shorter than IL, in case X of most recent Y number of atrial intervals have length shorter than IL, evaluates most recent =1 criteria, and controls a cardiac device depending on the classification. Atrial intervals are first evaluated by using the “X-out-of-Y” criterion and subsequently checked for stability after an atrial tachyarrhythmia is detected using “X-out-of-Y” criterion. For stability check, only intervals found shorter than the interval limit are used. Check is based on interval-to-interval comparison rather than as generally practiced, comparisons of individual intervals with the minimum or average of all intervals.
    • 用于分类获得预定义值的快速性心律失常的装置,监测心房间隔并且将每个间隔的长度与预定义值IL进行比较,如果长度短于IL,则存储心房间隔的长度,在最近的Y个心房间隔的情况下 长度短于IL,评估最近的<= N心房间隔,长度 = 1标准,则将心房快速性心律失常分类为稳定,并根据 分类。 首先通过使用“X-out-Y”标准来评估心房间隔,并随后在使用“X-out-of-Y”标准检测到房性快速性心律失常之后检查其稳定性。 对于稳定性检查,仅使用间隔时间间隔短于间隔限制。 检查是基于间隔间隔比较而不是通常实践的,将各个间隔与所有间隔的最小值或平均值进行比较。
    • 8. 发明申请
    • APPARATUS AND METHOD TO OPTIMIZE PACING PARAMETERS
    • 优化PAC参数的装置和方法
    • US20130079839A1
    • 2013-03-28
    • US13603418
    • 2012-09-05
    • Jie LianVolker LangHannes KraetschmerDirk Muessig
    • Jie LianVolker LangHannes KraetschmerDirk Muessig
    • A61N1/365
    • A61N1/3627A61B5/0402A61N1/36521A61N1/3682A61N1/3684A61N1/3686
    • The present disclosure refers to a heart stimulator comprising a stimulation control unit, a stimulation unit, an impedance measurement unit and an impedance evaluation unit. The stimulation control unit is operatively connected to the stimulation unit to control timing of stimulation pulses by said stimulation unit. The impedance measurement unit is configured to determine an impedance signal reflecting intracardiac impedance. The impedance evaluation unit is operatively connected to the impedance measurement unit and to the stimulation control unit and is configured to evaluate the impedance signal so as to determine an isovolumic contraction time, an isovolumic relaxation time, an ejection time and a filling time from said impedance signal. The stimulation control unit is further configured to control timing of stimulation pulses depending on a performance index.
    • 本公开涉及包括刺激控制单元,刺激单元,阻抗测量单元和阻抗评估单元的心脏刺激器。 刺激控制单元可操作地连接到刺激单元以控制所述刺激单元的刺激脉冲的定时。 阻抗测量单元被配置为确定反映心内阻抗的阻抗信号。 阻抗评估单元可操作地连接到阻抗测量单元和刺激控制单元,并被配置为评估阻抗信号,以便确定等容收缩时间,等容弛豫时间,喷射时间和来自所述阻抗的填充时间 信号。 刺激控制单元还被配置为根据性能指标来控制刺激脉冲的定时。
    • 9. 发明授权
    • Heart monitoring system and method
    • 心脏监测系统及方法
    • US08175709B2
    • 2012-05-08
    • US11668491
    • 2007-01-30
    • Jie LianHannes KraetschmerDirk Muessig
    • Jie LianHannes KraetschmerDirk Muessig
    • A61N1/362
    • A61B5/04017A61B5/0402A61B5/04525A61B5/7232
    • A system for heart monitoring comprises an IEGM input for an intracardiac electrocardiogram (IEGM) that is connected to an active filtering stage that is adapted to transform an incoming IEGM into an output ECG signal. The active filtering stage is connected to a filter characterization stage that is adapted to process a recorded, patient specific IEGM template and a corresponding SECG template and to adapt the filter characteristics of said active filtering stage such that the filter characteristics best characterize the input-output relationship between the IEGM template and the corresponding SECG template. As a consequence, the active filtering stage is adapted to transform an incoming IEGM such that the output ECG signal closely resembles a morphology of a corresponding SECG.
    • 用于心脏监测的系统包括用于心内心电图(IEGM)的IEGM输入,其连接到适用于将输入的IEGM变换为输出ECG信号的有源滤波级。 有源滤波级连接到滤波器表征阶段,其适于处理记录的,患者特异性IEGM模板和对应的SECG模板,并适应所述有源滤波级的滤波器特性,使得滤波器特性最好地表征输入 - 输出 IEGM模板与相应的SECG模板之间的关系。 因此,有源滤波阶段适于变换输入的IEGM,使得输出的ECG信号非常类似于对应的SECG的形态。