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1. 发明申请

US20180263707A1 SYSTEM AND METHOD FOR MAPPING NAVIGATION SPACE TO PATIENT SPACE IN A MEDICAL PROCEDURE 审中-公开
公开(公告)号：US20180263707A1
公开(公告)日：2018-09-20
申请号：US15537576
申请日：2015-07-21
申请人： Gal SELA , Dorothy LUI , Alexander Gyles PANTHER , Kelly Noel DYER
发明人： Gal SELA , Dorothy LUI , Alexander Gyles PANTHER , Kelly Noel DYER
IPC分类号： A61B34/20 , G06T7/30 , A61B90/00 , A61B5/00
CPC分类号： A61B34/20 , A61B5/0035 , A61B5/055 , A61B5/064 , A61B90/36 , A61B2034/2051 , A61B2034/2055 , A61B2034/2068 , A61B2090/363 , A61B2576/00 , G06F19/00 , G06T7/30 , G06T7/33 , G06T2207/10004 , G06T2207/10028 , G06T2207/10072 , G06T2207/10081 , G06T2207/10096 , G06T2207/10104 , G06T2207/10116 , G06T2207/10132 , G06T2207/20101
摘要： A medical navigation system is provided for registering a patient for a medical procedure with the medical navigation system using fiducial markers. The fiducial markers are placed on the patient prior to a 3D scan and the fiducial markers each have a target for use with a tracking system. The medical navigation system comprises a 3D scanner, a tracking system, a display, and a controller electrically coupled to the 3D scanner, the tracking system, and the display. The controller has a processor coupled to a memory. The controller is configured to: receive 3D scan data generated by the 3D scanner representative of a 3D scan of at least a portion of the patient, the 3D scan including the fiducial markers visible by the 3D scanner; load from the memory saved medical image data, the saved medical data including preoperative image data saved during a previous scan of at least a portion of the patient; receive position data from the tracking system based on the target for each of the fiducial markers; and perform a transformation mapping to create a single unified virtual coordinate space based on the 3D scan data, the position data, and the medical image data, and updating registration data of the medical navigation system based on the transformation mapping.

2. 发明申请

US20180103890A1 SYSTEM AND METHOD FOR IMAGING MACROPHAGE ACTIVITY USING DELTA RELAXATION ENHANCED MAGNETIC RESONANCE IMAGING 审中-公开
公开(公告)号：US20180103890A1
公开(公告)日：2018-04-19
申请号：US15534037
申请日：2015-03-11
申请人： Cameron Anthony PIRON , Chad Tyler HARRIS , Jeff STAINSBY , Alexander Gyles PANTHER
发明人： Cameron Anthony PIRON , Chad Tyler HARRIS , Jeff STAINSBY , Alexander Gyles PANTHER
IPC分类号： A61B5/00 , A61B5/055 , A61K49/10 , G01R33/44 , G01R33/56 , G01R33/50 , G01R33/48
CPC分类号： A61B5/414 , A61B5/055 , A61K49/101 , G01R33/445 , G01R33/4806 , G01R33/50 , G01R33/5601
摘要： A magnetic resonance imaging (MRI) system is provided for imaging immune response of soft tissue to therapy by, prior to therapy, administering a contrast agent to the soft tissue; imaging a region of interest using delta relaxation enhanced magnetic resonance (DREMR) to define a functional section; selectively sampling local cells in the functional section; conducting immuno-assay analysis on the sampled local cells; and following therapy, further imaging said region of interest using DREMR to assess immune response of said cells to therapy.

3. 发明申请

US20170160359A1 SYSTEM AND METHOD FOR MAGNETIC RESONANCE IMAGE ACQUISITION 有权
公开(公告)号：US20170160359A1
公开(公告)日：2017-06-08
申请号：US15321818
申请日：2014-09-15
申请人： Cameron Anthony PIRON , Alexander Gyles PANTHER , Chad Tyler HARRIS , Stephen B.E. MCFADYEN
发明人： Cameron Anthony PIRON , Alexander Gyles PANTHER , Chad Tyler HARRIS , Stephen B.E. MCFADYEN
IPC分类号： G01R33/46 , A61B5/055 , H03M1/18 , G01R33/54
CPC分类号： G01R33/4625 , A61B5/055 , G01R33/3621 , G01R33/4608 , G01R33/4616 , G01R33/54 , G01R33/565 , H03M1/183
摘要： A method of data acquisition at a magnetic resonance imaging (MRI) system is provided. The system receives at least a portion of raw data for an image, and detects anomalies in the portion of raw data received. When anomalies are detected, the system can correct those anomalies dynamically, without waiting for a new scan to be ordered. The system can attempt to scan the offending portion of the raw data, either upon detection of the anomaly or at some point during the scan. The system can also correct anomalies using digital correction methods based on expected values. The anomalies can be detected based on variations from thresholds, masks and expected values all of which can be obtained using one of the ongoing scan, previously performed scans and apriori information relating to the type of scan being performed.

4. 发明申请

US20170160355A1 SYSTEM AND METHOD FOR MAGNETIC RESONANCE COIL ARRANGEMENT 有权
公开(公告)号：US20170160355A1
公开(公告)日：2017-06-08
申请号：US15435343
申请日：2017-02-17
申请人： Cameron Anthony PIRON , Alexander Gyles PANTHER
发明人： Cameron Anthony PIRON , Alexander Gyles PANTHER
IPC分类号： G01R33/34 , G01R33/48 , G01R33/3415
CPC分类号： G01R33/34046 , G01R33/34007 , G01R33/34084 , G01R33/341 , G01R33/3415 , G01R33/365 , G01R33/385 , G01R33/4818 , G01R33/482 , G01R33/546 , G01R33/5608 , G01R33/565
摘要： A magnetic resonance imaging (MRI) system is provided. The system includes a main field magnet generating a main magnetic field B0. Moreover, the system further includes radio frequency (RF) receiver coils including a first combination of two coils, the two coils of the first combination decoupled based on quadrature decoupling such that the two coils of the first combination are able to receive signals orthogonal to each other and to B0. The two coils can be butterfly coils, the loop-plain of the butterfly coils arranged along a surface, the longitudinal axis of the butterfly coils being substantially orthogonal and crossing at substantially midpoint. The surface can be substantially orthogonal to B0 and be curved. The first of the two coils can also be a loop coil and the second of the two coils a butterfly coil.

5. 发明申请

US20160313426A1 ADAPTIVE ELECTROMAGNET FOR HIGH PERFORMANCE MAGNETIC RESONANCE IMAGING 有权
标题翻译：用于高性能磁共振成像的自适应电磁铁
公开(公告)号：US20160313426A1
公开(公告)日：2016-10-27
申请号：US14898545
申请日：2015-04-27
申请人： Chad Tyler HARRIS , Alexander Gyles PANTHER , Stephen B.E. MCFADYEN
发明人： Chad Tyler HARRIS , Alexander Gyles PANTHER , Stephen B.E. MCFADYEN
IPC分类号： G01R33/54 , G01R33/483 , G01R33/36 , H01F7/06
CPC分类号： G01R33/381 , G01R33/3664 , G01R33/385 , G01R33/3875 , G01R33/4833 , G01R33/543 , H01F7/064
摘要： A method of configuring a conducting grid of elements interconnected at intersecting nodes by switches is described. The method includes: constructing a background grid by connection of centroids of the cell shape of the conducting grid; identifying a subset of elements in the background grid that intersect the smooth pattern of loops; identifying a subset of elements in the conducting grid that intersect the subset of elements in the background grid; the subset of elements in the conducting grid forming a discretized pattern of loops representing the smooth pattern of loops; for each of the discretized pattern of loops identifying current-in and current-out nodes; altering the on-off state of individual switches in accordance with the discretized pattern of loops; opening the switch between each respective pair of current-in and current out nodes; and applying power to the conducting grid via at least one pair of the input and output current nodes such that the current flow through the elements generates the magnetic field profile.
摘要翻译：描述了通过交换机在交叉节点处互连的元件的导电栅格的配置方法。该方法包括：通过连接导电栅格的单元格形状的质心来构建背景网格; 识别背景网格中与循环平滑模式相交的元素的子集; 识别导电网格中与背景网格中的元素子集相交的元素的子集; 导电栅格中的元素的子集形成表示环的平滑图案的环的离散模式; 对于每个离散的模式的环路识别电流输入和电流输出节点; 根据循环的离散模式改变各个开关的开关状态; 在每个相应的一对电流输入和当前输出节点之间打开开关; 以及经由至少一对所述输入和输出电流节点向所述导电栅格施加电力，使得通过所述元件的电流产生所述磁场分布。

6. 发明申请

US20180000467A1 AUTOMATED AUTOPSY SYSTEM 审中-公开
公开(公告)号：US20180000467A1
公开(公告)日：2018-01-04
申请号：US14902723
申请日：2015-03-23
申请人： Kai Michael HYNNA , Joshua Lee RICHMOND , Alexander Gyles PANTHER , Thanh Vinh VUONG
发明人： Kai Michael HYNNA , Joshua Lee RICHMOND , Alexander Gyles PANTHER , Thanh Vinh VUONG
IPC分类号： A61B16/00 , A61B34/20 , A61B90/00 , G06F19/00
CPC分类号： A61B16/00 , A61B34/20 , A61B90/36 , A61B90/361 , A61B2034/2055 , A61B2090/3735 , A61B2090/374 , A61B2090/376 , A61B2090/378 , G16H40/63
摘要： A medical navigation system is provided for performing at least part of an assessment of a non-living body. The medical navigation system comprises a positioning device having a positioning arm with an end effector at the end of the positioning arm, an imaging device coupled to the end effector, and a controller electrically coupled to the positioning device and the imaging device. The controller has a processor coupled to a memory and a display. The controller is configured to generate a signal to move the positioning arm to position the imaging device through a range of motion to perform a scan of a surface of the body and receive and save as data in the memory signals generated by the imaging device during the range of motion.

7. 发明申请

US20170293005A1 SYSTEM AND METHOD FOR DELTA RELAXATION ENHANCED MAGNETIC RESONANCE IMAGING 审中-公开
公开(公告)号：US20170293005A1
公开(公告)日：2017-10-12
申请号：US14902221
申请日：2015-02-23
申请人： Alexander Gyles PANTHER , Cameron Anthony PIRON , Jeff Alan STAINSBY , Chad Tyler HARRIS
发明人： Alexander Gyles PANTHER , Cameron Anthony PIRON , Jeff Alan STAINSBY , Chad Tyler HARRIS
IPC分类号： G01R33/44 , G01R33/56
CPC分类号： G01R33/445 , A61B5/00 , A61B5/05 , G01R33/5602 , G01R33/56518
摘要： A delta-relaxation magnetic resonance imaging (DREMR) system is provided. The system includes a main field magnet and field shifting coils. A main magnetic field with a strength B0 can be generated using the main filed magnet and the strength B0 of the main magnetic field can be varied through the use of the field-shifting coils. The DREMR system can be used to perform signal acquisition based on a pulse sequence for acquiring at least one of T2*-weighted signals imaging; MR spectroscopy signals; saturation imaging signals and MR signals for fingerprinting. The MR signal acquisition can be augmented by varying the strength B0 of the main magnetic field for at least a portion of the pulse sequence used to acquire the MR signal.

8. 发明申请

US20180031654A1 SYSTEM AND METHOD FOR MAGNETIC RESONANCE IMAGE ACQUISITION 审中-公开
公开(公告)号：US20180031654A1
公开(公告)日：2018-02-01
申请号：US15705819
申请日：2017-09-15
申请人： Cameron Anthony PIRON , Alexander Gyles PANTHER , Chad Tyler HARRIS , Stephen B.E. MCFADYEN
发明人： Cameron Anthony PIRON , Alexander Gyles PANTHER , Chad Tyler HARRIS , Stephen B.E. MCFADYEN
IPC分类号： G01R33/46 , G01R33/54 , A61B5/055 , H03M1/18
CPC分类号： G01R33/4625 , A61B5/055 , G01R33/3621 , G01R33/4608 , G01R33/4616 , G01R33/54 , G01R33/565 , H03M1/183
摘要： A system and method of acquiring an image at a magnetic resonance imaging (MRI) system is provided. Accordingly, an analog signal based on a pulse sequence and a first gain is obtained. The analog signal is converted into a digitized signal. A potential quantization error is detected in the digitized signal based on a boundary. When the detection is affirmative, a replacement analog signal based on the pulse sequence is received. At least one portion of the replacement analog signal can be based on an adjusted gain. The adjusted gain is a factor of the first gain. The replacement analog signal is digitized into a replacement digitized signal. At least one portion of the replacement digitized signal corresponding to the at least one portion of the replacement analog signal is adjusted based on a reversal of the factor.

9. 发明申请

US20170258528A1 MEDICAL IMAGING SYSTEM FOR ILLUMINATING TISSUE SAMPLES USING THREE-DIMENSIONAL STRUCTURED ILLUMINATION MICROSCOPY 审中-公开
公开(公告)号：US20170258528A1
公开(公告)日：2017-09-14
申请号：US15035295
申请日：2015-08-24
申请人： Yanhui BAI , Michael Frank Gunter WOOD , Siu Wai Jacky MAK , Murugathas YUWARAJ , Alexander Gyles PANTHER , Sean Jy-Shyang CHEN
发明人： Yanhui BAI , Michael Frank Gunter WOOD , Siu Wai Jacky MAK , Murugathas YUWARAJ , Alexander Gyles PANTHER , Sean Jy-Shyang CHEN
IPC分类号： A61B34/20 , A61B1/05 , A61B1/00 , H04N13/02 , H04N5/335 , G02B23/24 , G02B27/30 , G02B21/02 , G02B21/04 , G02B21/06 , G02B21/36 , A61B1/06 , G02B21/00
CPC分类号： A61B34/20 , A61B1/00045 , A61B1/00188 , A61B1/05 , A61B1/06 , A61B5/0071 , A61B5/062 , A61B5/064 , A61B5/4064 , A61B17/34 , A61B90/20 , A61B90/30 , A61B90/361 , A61B2034/2055 , A61B2090/309 , A61B2505/05 , G01B11/25 , G02B21/0012 , G02B21/0052 , G02B21/0064 , G02B21/008 , G02B21/025 , G02B21/04 , G02B21/06 , G02B21/361 , G02B23/2415 , G02B23/2484 , G02B27/30 , H04N5/335 , H04N13/254 , H04N2213/001
摘要： A medical imaging system for illuminating tissue samples using three-dimensional structured illumination microscopy is port-based surgery is provided. The system comprises: an image sensor; a mirror device; zoom optics; a light modulator; a processor; and collimating optics configured to convey one or more images from the modulator to the mirror, the mirror configured to convey the images to the zoom optics, the zoom optics configured: to convey the image(s) from the mirror to a tissue sample; and convey one or more resulting images, formed by the image(s) illuminating the sample, back to the mirror, which conveys the resulting image(s) from the zoom optics to the image sensor, and, the processor configured to control the modulator to form the image(s), the image(s) including at least one pattern selected to interact with the sample to generate different depth information in each of resulting image(s).

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