专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120055467A1 METERED-DOSE INHALER AND METHOD OF USING THE SAME 审中-公开
标题翻译：计量吸入器及其使用方法
公开(公告)号：US20120055467A1
公开(公告)日：2012-03-08
申请号：US13226017
申请日：2011-09-06
申请人： Gaetano Brambilla , David Andrew Lewis , Robert Johnson , David Howlett
发明人： Gaetano Brambilla , David Andrew Lewis , Robert Johnson , David Howlett
IPC分类号： A61M11/00 , A61M16/14
CPC分类号： A61M15/009 , A61J1/2037 , A61J1/2089 , A61M15/0003 , B65D83/54 , B65D83/682
摘要： A metered-dose inhaler includes at least one vessel and an actuator for receiving the at least one vessel. The at least one vessel includes a first reservoir containing a first formulation and a second reservoir containing a second formulation. The metered-dose inhaler is actuable when the at least one vessel is received by the actuator. The metered-dose inhaler is configured to simultaneously deliver a first metered dose of the first formulation and a second metered dose of the second formulation upon actuation.
摘要翻译：计量吸入器包括至少一个容器和用于容纳至少一个容器的致动器。所述至少一个容器包括含有第一制剂的第一储存器和含有第二制剂的第二储存器。当至少一个容器被致动器接收时，计量吸入器是致动的。计量吸入器构造成在致动时同时递送第一制剂的第一计量剂量和第二制剂的第二计量剂量。

2. 发明申请

US20120055468A1 METERED-DOSE INHALER ACTUATOR, METERED-DOSE INHALER AND METHOD OF USING THE SAME 审中-公开
标题翻译：计量吸入器致动器，计量吸入器及其使用方法
公开(公告)号：US20120055468A1
公开(公告)日：2012-03-08
申请号：US13226005
申请日：2011-09-06
申请人： Gaetano Brambilla , David Andrew Lewis , Robert Johnson
发明人： Gaetano Brambilla , David Andrew Lewis , Robert Johnson
IPC分类号： A61M11/02 , A61M15/00
CPC分类号： A61M15/009 , A61M2206/10 , A61M2206/16
摘要： An actuator for a metered-dose inhaler is provided. The actuator comprises a housing having a mouthpiece portion and a canister receiving portion configured to receive a canister. The actuator further comprises a member disposed within the housing and defining a valve stem receptacle configured to receive a valve stem of the canister. An orifice is formed in the member, which is in fluid communication with the valve stem receptacle and extending to a face of the member opposite to the valve stem receptacle. A longitudinal axis of the orifice is aligned with a longitudinal axis of the valve stem receptacle. At least one air inlet opening is provided in an outer shell of the housing so as to be spaced from an opening for receiving the canister and a mouthpiece opening.
摘要翻译：提供用于计量吸入器的致动器。致动器包括具有接口部分的壳体和被配置为容纳罐的罐接收部分。所述致动器还包括设置在所述壳体内的构件，并且限定构造成容纳所述罐的阀杆的阀杆容置孔。在所述构件中形成孔口，所述孔口与所述阀杆插座流体连通并且延伸到所述构件的与所述阀杆插座相对的面。孔口的纵向轴线与阀杆容器的纵向轴线对准。至少一个空气入口开口设置在壳体的外壳中，以与用于容纳罐的开口和接口开口间隔开。

3. 发明授权

US08088362B2 Salmeterol superfine formulation 失效
标题翻译：沙美特罗超细配方
公开(公告)号：US08088362B2
公开(公告)日：2012-01-03
申请号：US10531867
申请日：2003-06-18
申请人： Tanya Kathleen Church , David Andrew Lewis , David Ganderton , Brian John Meakin , Gaetano Brambilla
发明人： Tanya Kathleen Church , David Andrew Lewis , David Ganderton , Brian John Meakin , Gaetano Brambilla
IPC分类号： A61K9/12 , A61K9/00
CPC分类号： A61K9/008 , A61K31/4704 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a pharmaceutical formulation for use in the administration of a long-acting β2-agonist by inhalation. In particular this invention relates to a chemically stable, highly efficient salmeterol HFA solution formulation to be administered by pressurized metered dose inhalers (pMDIs) characterized by a deep lung penetration. The invention also relates to methods for the preparation of said formulation and to its use in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
摘要翻译：本发明涉及用于通过吸入施用长效2-激动剂的药物制剂。特别地，本发明涉及一种化学稳定，高效的沙美特罗HFA溶液制剂，其由以深肺渗透为特征的加压计量剂量吸入器（pMDI）施用。本发明还涉及制备所述制剂及其在呼吸系统疾病如哮喘和慢性阻塞性肺疾病（COPD）中的应用的方法。

4. 发明申请

US20090020114A1 METERED DOSE INHALER ACTUATOR 审中-公开
标题翻译：计量剂量吸入器执行器
公开(公告)号：US20090020114A1
公开(公告)日：2009-01-22
申请号：US12167508
申请日：2008-07-03
申请人： Gaetano BRAMBILLA , Tanya Kathleen Church , David Andrew Lewis , Brian John Meakin
发明人： Gaetano BRAMBILLA , Tanya Kathleen Church , David Andrew Lewis , Brian John Meakin
IPC分类号： A61M15/00 , A61M11/04
CPC分类号： A61M15/009
摘要： Metered dose inhaler actuators for pressurised aerosol containing a formulation of at least one medicament in a liquefied propellant gas which comprise: a nozzle block 5 having a bore 11 to receive a valve stem 7; a sump 8 in connection with a bore 11, wherein the propellant formulation expands upon actuation of the inhaler; a nozzle channel 6, exiting from the sump 8 and aligned with a mouthpiece 4, wherein the sump 8 has an internal volume between 2 and 12 mm3 prevent the deposition of the medicament during the delivery into the chamber and/or into the nozzle channel. a reduction in the delivered dose, and an increase in the occurrence of the clogging of the inhaler. Such actuators are particularly useful for the administration of pressurised metered dose inhaler formulations, in solution and/or in suspension, wherein the concentration of the active ingredient(s) of the formulation is/are particularly high and in particular suitable to administer at least 100 μg/dose, preferably at least 200 μg/dose, even more preferably at least 400 μg/dose.
摘要翻译：含有液化推进剂气体中的至少一种药物制剂的用于加压气雾剂的计量剂量吸入器致动器，包括：具有用于接收阀杆7的孔11的喷嘴块5; 与孔11相连的贮槽8，其中推进剂制剂在吸入器致动时膨胀; 从贮槽8排出并与接口管4对准的喷嘴通道6，其中贮槽8具有在2和12mm 3之间的内部容积，防止药物在输送到腔室和/或进入喷嘴通道期间沉积。递送剂量的减少以及吸入器堵塞的发生的增加。这种致动器特别可用于在溶液和/或悬浮液中施用加压计量剂量吸入器制剂，其中制剂的活性成分的浓度特别高，特别适合施用至少100 优选至少200μg/剂量，甚至更优选至少400mug /剂量。

5. 发明申请

US20110061651A1 FORMOTEROL SUPERFINE FORMULATION 有权
标题翻译：福莫司他汀制剂
公开(公告)号：US20110061651A1
公开(公告)日：2011-03-17
申请号：US12873690
申请日：2010-09-01
申请人： Rebecca Jaine DAVIES , David Ganderton , David Andrew Lewis , Brian John Meakin , Tanya Kathleen Church , Gaetano Brambilla , Alessandra Ferraris
发明人： Rebecca Jaine DAVIES , David Ganderton , David Andrew Lewis , Brian John Meakin , Tanya Kathleen Church , Gaetano Brambilla , Alessandra Ferraris
IPC分类号： A61M15/00 , B65B31/10 , A61J1/05
CPC分类号： A61K9/008 , A61K31/4704 , A61K31/485 , A61K45/06 , A61K47/10 , A61K2300/00
摘要： A metal container and a method of preparing a metal container for a pharmaceutical formulation where the active ingredient is formoterol, a stereoisomer of formoterol, and a physiologically acceptable salt of formoterol, in a solution of a liquefied HFA propellant.
摘要翻译：在液化HFA推进剂的溶液中，金属容器和制备用于药物制剂的金属容器的方法，其中活性成分是福莫特罗，福莫特罗的立体异构体和福莫特罗的生理学上可接受的盐。

6. 发明授权

US08313732B2 Formoterol superfine formulation 有权
标题翻译：福莫特罗超细制剂
公开(公告)号：US08313732B2
公开(公告)日：2012-11-20
申请号：US12873690
申请日：2010-09-01
申请人： Rebecca Jaine Davies , David Ganderton , David Andrew Lewis , Brian John Meakin , Tanya Kathleen Church , Gaetano Brambilla , Alessandra Ferraris
发明人： Rebecca Jaine Davies , David Ganderton , David Andrew Lewis , Brian John Meakin , Tanya Kathleen Church , Gaetano Brambilla , Alessandra Ferraris
IPC分类号： A61K9/00 , A61K9/08 , A61K9/12
CPC分类号： A61K9/008 , A61K31/4704 , A61K31/485 , A61K45/06 , A61K47/10 , A61K2300/00
摘要： A metal container and a method of preparing a metal container for a pharmaceutical formulation where the active ingredient is formoterol, a stereoisomer of formoterol, and a physiologically acceptable salt of formoterol, in a solution of a liquefied HFA propellant.
摘要翻译：在液化HFA推进剂的溶液中，金属容器和制备用于药物制剂的金属容器的方法，其中活性成分是福莫特罗，福莫特罗的立体异构体和福莫特罗的生理学上可接受的盐。

7. 发明申请

US20090263488A1 PRESSURISED METERED DOSE INHALERS CONTAINING SOLUTIONS OF BETA-2 AGONISTS 审中-公开
标题翻译：含有BETA-2激动剂解决方案的压力计量剂吸入剂
公开(公告)号：US20090263488A1
公开(公告)日：2009-10-22
申请号：US12487988
申请日：2009-06-19
申请人： Rebecca Jaine Davies , David Ganderton , David Andrew Lewis , Brian John Meakin , Tanya Kathleen Church , Gaetano Brambilla , Alessandra Ferraris
发明人： Rebecca Jaine Davies , David Ganderton , David Andrew Lewis , Brian John Meakin , Tanya Kathleen Church , Gaetano Brambilla , Alessandra Ferraris
IPC分类号： A61K9/14 , A61K31/4704 , A61P11/00
摘要： The present invention relates to a pharmaceutical formulation for use in the administration of 2(1H)-quinolinone derivatives long-acting β2-agonists by inhalation. In particular this invention relates to a chemically stable highly efficient TA 2005 HFA solution formulation to be administered by pressurised metered dose inhalers (pMDIs) characterized by a deep lung penetration. The invention also relates to methods for the preparation of said formulation and to its use in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
摘要翻译：本发明涉及用于通过吸入给药2（1H） - 喹啉酮衍生物长效β2-激动剂的药物制剂。特别地，本发明涉及一种化学稳定高效的TA 2005 HFA溶液制剂，其通过深层肺穿透特征的加压计量剂量吸入器（pMDI）来施用。本发明还涉及制备所述制剂及其在呼吸系统疾病如哮喘和慢性阻塞性肺疾病（COPD）中的应用的方法。

8. 发明授权

US07695776B2 Transparent hard coats for optical elements 失效
标题翻译：用于光学元件的透明硬涂层
公开(公告)号：US07695776B2
公开(公告)日：2010-04-13
申请号：US12154568
申请日：2008-05-23
申请人： Jeffrey Curtis Hedrick , David Andrew Lewis , Stanley Joseph Whitehair
发明人： Jeffrey Curtis Hedrick , David Andrew Lewis , Stanley Joseph Whitehair
IPC分类号： H05H1/24
CPC分类号： C23C16/308 , Y10S428/911 , Y10T428/24975 , Y10T428/24983 , Y10T428/265
摘要： The present invention related to an improved structure of an optically transparent element that can be used in optical scanners, supermarket scanners, lenses for eyeglasses, etc. The application of oxynitride PECVD films provide good hardness and optical transparency. Such films displaying these physical properties are extremely useful as a scratch resistant coatings in lenses and systems in which an article contacts a transparent surface, such as in scanners and in environments in which intermittent, environmental contact occurs such as in displays for computers and suchlike and in liquid crystal displays, touch displays and compact disks.
摘要翻译：本发明涉及可用于光学扫描仪，超市扫描仪，眼镜镜片等的光学透明元件的改进结构。氮氧化物PECVD膜的应用提供了良好的硬度和光学透明度。显示这些物理性质的这样的薄膜作为防透光涂料在透镜和系统中是非常有用的，所述透镜和系统中的物品接触透明表面，例如在扫描仪中以及在诸如计算机等的显示器中发生间歇性环境接触的环境中，在液晶显示器，触摸显示器和光盘中。

9. 发明授权

US6097019A Radiation control system 失效
公开(公告)号：US6097019A
公开(公告)日：2000-08-01
申请号：US129708
申请日：1998-08-05
申请人： David Andrew Lewis , Jane Margaret Shaw , Michael Hatzakis
发明人： David Andrew Lewis , Jane Margaret Shaw , Michael Hatzakis
IPC分类号： B01J19/12 , G01N22/00 , H05B6/68 , H05B6/70 , H05B6/74 , H05B6/80
CPC分类号： H05B6/806 , B01J19/126 , G01N22/00 , H05B6/6402 , H05B6/70 , H05B6/705 , B01J2219/00191 , H05B2206/046
摘要： A control system for a blind microwave radiation tool a workpiece is described. The controlled system automatically tunes the cavity containing the workpiece. The control system automatically controls the temperature of the workpiece according to a predetermined temperature versus time schedule. Control system automatically determines when the workpiece has reached a particular predetermined physical condition. To achieve these results the control system automatically monitors applied power, reflected power or current temperature and automatically controls the microwave cavity volume and shape and launch structure including antennae location, cavity short location, cavity diameter, coupling loop position, etc. in order to maintain the cavity in resonance and to determine when to exit without operator intervention. Control system can run on a small computer or an embedded controller and is useful for automatically curing polyamic acid to polyimide to a predetermined percent cure, processing preimpregnated glass cloth in a continuous manner which can be used in circuit boards and drying and partial curing of web-like materials automatically without operator intervention.

10. 发明授权

US6054696A Feedback system to automatically couple microwave energy into an applicator 失效
标题翻译：将微波能量自动耦合到施加器中的反馈系统
公开(公告)号：US6054696A
公开(公告)日：2000-04-25
申请号：US2719
申请日：1998-01-05
申请人： David Andrew Lewis , Stanley Joseph Whitehair
发明人： David Andrew Lewis , Stanley Joseph Whitehair
IPC分类号： B01J19/12 , G01N22/00 , H05B6/68 , H05B6/70 , H05B6/74 , H05B6/80
CPC分类号： H05B6/686 , B01J19/126 , G01N22/00 , H05B6/6402 , H05B6/70 , H05B6/705 , B01J2219/00191 , Y02B40/143 , Y02B40/146
摘要： A microwave processing system comprising a microwave applicator and a microwave source. A microwave source generates a microwave field at an output frequency. A frequency of the microwave field in the elongated chamber and the output frequency of the microwave source are matched through the use of controlled feedback of critical material and process parameters.
摘要翻译：一种包括微波施加器和微波源的微波处理系统。微波源以输出频率产生微波场。通过使用关键材料和工艺参数的受控反馈来匹配细长室中的微波场频率和微波源的输出频率。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式