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1. 发明申请

US20120192317A1 SELECTING AND STABILIZING dsRNA CONSTRUCTS 审中-公开
标题翻译：选择和稳定dsRNA构建体
公开(公告)号：US20120192317A1
公开(公告)日：2012-07-26
申请号：US13305688
申请日：2011-11-28
申请人： GREGORY R. HECK , Tichafa R. I. Munyikwa , Jean C. Goley , James K. Roberts , Scott C. Johnson , Ty T. Vaughn
发明人： GREGORY R. HECK , Tichafa R. I. Munyikwa , Jean C. Goley , James K. Roberts , Scott C. Johnson , Ty T. Vaughn
IPC分类号： A01N57/16 , C12N15/63 , A01P7/04 , C12N15/113 , A01H5/00 , A01P15/00 , C12N5/10 , A01N37/46
CPC分类号： C12N15/113 , C12N15/111 , C12N15/8218 , C12N15/8286 , C12N2310/14 , C12N2320/10 , Y02A40/162
摘要： The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.
摘要翻译：本发明提供了选择在目标生物体中产生dsRNA介导的基因抑制并使其能够被靶生物吸收的核苷酸序列的方法。本发明进一步提供赋予转基因宿主细胞中此类序列稳定表达的表达构建体及其使用方法。还提供了通过本发明的方法制备的生物，细胞和组织。

2. 发明授权

US10941398B2 Selecting and stabilizing dsRNA constructs 有权
公开(公告)号：US10941398B2
公开(公告)日：2021-03-09
申请号：US13305688
申请日：2011-11-28
申请人： Gregory R. Heck , Tichafa R. I. Munyikwa , Jean C. Goley , James K. Roberts , Scott C. Johnson , Ty T. Vaughn
发明人： Gregory R. Heck , Tichafa R. I. Munyikwa , Jean C. Goley , James K. Roberts , Scott C. Johnson , Ty T. Vaughn
IPC分类号： C12N15/82 , C12N15/113 , C12N15/11
摘要： The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.

3. 发明申请

US20090117539A1 DNA sequences for gene suppression 审中-公开
标题翻译：用于基因抑制的DNA序列
公开(公告)号：US20090117539A1
公开(公告)日：2009-05-07
申请号：US11399000
申请日：2006-04-05
申请人： Larry Gilbertson , Scott C. Johnson , David K. Kovalic , Tracey L. Reynolds , James F. Rice, JR. , James K. Roberts
发明人： Larry Gilbertson , Scott C. Johnson , David K. Kovalic , Tracey L. Reynolds , James F. Rice, JR. , James K. Roberts
IPC分类号： C12Q1/68 , C12N5/06
CPC分类号： C12Q1/6895
摘要： The present invention provides methods of improving DNA sequences for gene suppression mediated by double-stranded RNA, and constructs and transgenic organisms containing such improved DNA sequences.
摘要翻译：本发明提供了改进由双链RNA介导的基因抑制的DNA序列的方法，以及含有这种改良的DNA序列的构建体和转基因生物。

4. 发明授权

US07475374B1 Clock grid driven by virtual leaf drivers 有权
标题翻译：由虚拟叶驱动器驱动的时钟网格
公开(公告)号：US07475374B1
公开(公告)日：2009-01-06
申请号：US11314698
申请日：2005-12-20
申请人： Scott C. Johnson , Don Walters , Ravinder Rachala , Jerry Moench
发明人： Scott C. Johnson , Don Walters , Ravinder Rachala , Jerry Moench
IPC分类号： G06F17/50 , G06F9/45
CPC分类号： G06F17/505 , G06F2217/62
摘要： Various embodiments of methods and systems for providing virtual leaf driver nodes in a clock tree to drive a clock grid of an integrated circuit are disclosed. An integrated circuit may include a large number of clocked elements such as registers, flip-flops, etc. whose operation is synchronized by one or more clocks. For example, an operation performed by circuitry on one side of the die may need to occur at precisely the same time as another operation performed by circuitry on the other side of the die. In order to assure synchronicity of these events, a clock grid may be provided in the IC that is driven by virtual leaf driver nodes. The clock tree driving the clock grid may include a tier of leaf buffers. The output of a leaf buffer may be split, and the branches of the output connected to separate points on the clock grid.
摘要翻译：公开了用于在时钟树中提供虚拟叶驱动器节点以驱动集成电路的时钟网格的方法和系统的各种实施例。集成电路可以包括大量的时钟元件，例如寄存器，触发器等，其操作通过一个或多个时钟同步。例如，由芯片的一侧上的电路执行的操作可能需要在与芯片另一侧上的电路执行的另一操作完全相同的时间进行。为了确保这些事件的同步性，可以在IC中提供由虚拟叶驱动器节点驱动的时钟网格。驱动时钟网格的时钟树可以包括一层叶缓冲器。叶片缓冲区的输出可能被分割，输出的分支连接到时钟网格上的分离点。

5. 发明授权

US5351350A Dusper 失效
标题翻译：杜斯
公开(公告)号：US5351350A
公开(公告)日：1994-10-04
申请号：US75707
申请日：1993-05-06
申请人： Scott C. Johnson
发明人： Scott C. Johnson
IPC分类号： A46B17/08 , B25F1/00 , B25G3/02 , B25G3/26 , B44D3/16 , E04F21/28
CPC分类号： B25G3/26 , A46B17/08 , B25F1/00 , B25G3/02 , B44D3/162
摘要： A tool for scraping paint and dusting the loosened particles away. The tool fits in the pocket of the painter's overalls which is designed for the scraper alone, and it eliminates the need for a separate brush or rag to dust a surface clean for painting. The Dusper has snapping pins on the handle for removing and replacing the brush.
摘要翻译：用于刮除油漆并将松散的颗粒除去的工具。该工具适合画家工作服的口袋，专为刮刀而设计，不需要单独的刷子或抹布来清洁表面。 Dusper在手柄上具有卡扣销，用于拆卸和更换刷子。

6. 发明授权

US5201083A Seating type article of furniture convertible into a bed 失效
标题翻译：座椅式家具可转换成床
公开(公告)号：US5201083A
公开(公告)日：1993-04-13
申请号：US786712
申请日：1991-11-01
申请人： Scott C. Johnson
发明人： Scott C. Johnson
IPC分类号： A47C17/175
CPC分类号： A47C17/175
摘要： An article of furniture that is convertible from a couch configuration into a bed configuration. The ability to convert the article is provided by a two pieced frame assembly including a seat section and a back section which are pivotally attached preferably at only two discreet points. The back section is provided with legs that support the back section in a horizontal position when the article is in its bed configuration which, in turn, is attached by pivots to the rear portion of the seat section and supports same. The front portion of the seat section is supported by separate legs.
摘要翻译：可从沙发配置转换成床配置的家具物品。转换物品的能力由两个拼接框架组件提供，该组合框架包括一个座椅部分和一个后部，其优选地仅枢转地附接在两个离散点上。背部设置有腿部，当腿部构件处于其床构造时，后腿部支撑在水平位置，后者又通过枢轴附接到座椅部分的后部并支撑其。座椅部分的前部由独立的腿支撑。

7. 外观设计

USD268768S Telescope 失效
公开(公告)号：USD268768S
公开(公告)日：1983-04-26
申请号：US185617
申请日：1980-09-09
申请人： Frank M. Melsheimer , Thomas T. Melsheimer , Scott C. Johnson , John C. Diebel
设计人： Frank M. Melsheimer , Thomas T. Melsheimer , Scott C. Johnson , John C. Diebel

8. 发明授权

US08719598B2 Power OK distribution for multi-voltage chips 有权
标题翻译：多功能电源芯片的Power OK配置
公开(公告)号：US08719598B2
公开(公告)日：2014-05-06
申请号：US12828880
申请日：2010-07-01
申请人： Shawn Searles , Scott C. Johnson , Grace I. Chuang
发明人： Shawn Searles , Scott C. Johnson , Grace I. Chuang
IPC分类号： G06F1/28 , G06F1/30
CPC分类号： G06F1/28
摘要： A method and apparatus for powering up an integrated circuit (IC). An IC includes a plurality of power domains each coupled to receive power from one of a plurality of power sources. Each power domain includes a power-sensing unit. A power-sensing unit in a first one of the plurality of power domains is coupled to receive a first power ok signal from an upstream power domain, and is configured to assert a second power ok signal to be provided to a second power domain. A power-sensing unit in the second power domain is coupled to detect the presence of voltage in the first power domain, and to receive the first power ok signal. When the power-sensing unit in the second power domain has both sensed the presence of power in the first power domain and received the second power ok signal, a third power ok signal is asserted.
摘要翻译：一种用于为集成电路（IC）供电的方法和装置。 IC包括多个功率域，每个功率域被耦合以从多个电源之一接收功率。每个功率域包括功率感测单元。多个功率域中的第一个功率区中的功率感测单元被耦合以从上游功率域接收第一功率ok信号，并且被配置为断言要提供给第二功率域的第二功率ok信号。耦合第二功率域中的功率感测单元以检测第一功率域中的电压的存在并接收第一功率ok信号。当第二功率域中的功率感测单元已经感测到在第一功率域中存在功率并且接收到第二功率ok信号时，断言第三功率确认信号。

9. 发明申请

US20100281181A1 NETWORK ABSTRACTION AND ISOLATION LAYER FOR MASQUERADING MACHINE IDENTITY OF A COMPUTER 有权
标题翻译：计算机主机识别的网络摘要和隔离层
公开(公告)号：US20100281181A1
公开(公告)日：2010-11-04
申请号：US12838009
申请日：2010-07-16
申请人： Scott C. Johnson , Dave D. McCrory
发明人： Scott C. Johnson , Dave D. McCrory
IPC分类号： G06F15/16
CPC分类号： H04L63/0407 , H04L63/16
摘要： A network abstraction and isolation layer (NAIL) for masquerading the machine identity of a computer in a network to enable the computer to communicate in the network with a different machine identity including an isolated network interface for communicating with the computer, an abstraction network interface for communicating with a network device coupled to the network, and control instructions or device. The control instructions or device performs machine identity translation to masquerade machine identity of the computer relative to the network. Machine identity masquerading includes selectively translating any one or more of an IP address, a MAC address, a machine name, a system identifier, and a DNS Name in the header or payload of communication packets.
摘要翻译：一种用于伪装网络中的计算机的机器标识的网络抽象和隔离层（NAIL），以使计算机能够在网络中与不同的机器标识进行通信，包括用于与计算机进行通信的隔离网络接口，用于与耦合到网络的网络设备进行通信，以及控制指令或设备。控制指令或设备执行机器标识转换，以相对于网络伪装计算机的机器标识。机器识别伪装包括在通信包的头部或有效载荷中选择性地翻译IP地址，MAC地址，机器名称，系统标识符和DNS名称中的一个或多个。

10. 发明授权

US07514212B2 Nucleic acid amplification using non-standard bases 有权
标题翻译：使用非标准碱的核酸扩增
公开(公告)号：US07514212B2
公开(公告)日：2009-04-07
申请号：US10542464
申请日：2004-01-17
申请人： James R. Prudent , Scott C. Johnson , Michael J. Moser , David J. Marshall
发明人： James R. Prudent , Scott C. Johnson , Michael J. Moser , David J. Marshall
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6853 , C12Q1/6844 , C12Q2525/101
摘要： The present invention provides methods, kits and compositions for high fidelity nucleic acid amplification reactions of target nucleic acids such that specific amplification products that incorporate non-standard bases are produced. The amplification reactions can either be linear or exponential. In some embodiments, the fidelity of the amplification reaction is high enough such that a majority of the amplification products maintain non-standard bases at specific sites designated by the user after a specified number of amplification cycles. In some embodiments, the ratio of non-standard nucleoside triphosphates is greater than the amount of standard nucleoside triphosphates initially present in the reaction mixture.
摘要翻译：本发明提供用于靶核酸的高保真度核酸扩增反应的方法，试剂盒和组合物，从而产生包含非标准碱基的特异性扩增产物。扩增反应可以是线性的或指数的。在一些实施方案中，扩增反应的保真度足够高，使得大部分扩增产物在指定数量的扩增循环后由用户指定的特定位点维持非标准碱基。在一些实施方案中，非标准核苷三磷酸的比例大于最初存在于反应混合物中的标准核苷三磷酸的量。

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