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1. 发明申请

WO2012165914A3 NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS 审中-公开
标题翻译：新型二苯甲基衍生物作为SGLT2抑制剂
公开(公告)号：WO2012165914A3
公开(公告)日：2013-03-28
申请号：PCT/KR2012004366
申请日：2012-06-01
申请人： GREEN CROSS CORP , CHOI SOONGYU , SONG KWANG-SEOP , LEE SUK HO , KIM MIN JU , SEO HEE JEONG , PARK EUN-JUNG , KONG YOUNGGYU , PARK SO OK , KANG HYUNKU , JUNG MYUNG EUN , LEE KINAM , KIM HYUN JUNG , LEE JUN SUNG , LEE MIN WOO , KIM MI-SOON , HONG DONG HO , KANG MISUK
发明人： CHOI SOONGYU , SONG KWANG-SEOP , LEE SUK HO , KIM MIN JU , SEO HEE JEONG , PARK EUN-JUNG , KONG YOUNGGYU , PARK SO OK , KANG HYUNKU , JUNG MYUNG EUN , LEE KINAM , KIM HYUN JUNG , LEE JUN SUNG , LEE MIN WOO , KIM MI-SOON , HONG DONG HO , KANG MISUK
IPC分类号： A61K31/357 , A61K31/015 , A61K31/343 , A61K31/35 , A61P3/00
CPC分类号： C07D309/10 , C07D405/10 , C07D405/14 , C07D407/04 , C07D407/10 , C07D407/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D411/10 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14
摘要： The present invention relates to a compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The present invention also provides a method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound.
摘要翻译：本发明涉及具有对存在于肠和肾中的钠依赖性葡萄糖协同转运蛋白2（SGLT2）具有抑制活性的二苯基甲烷部分的化合物和包含其作为活性成分的药物组合物，其可用于预防或治疗代谢紊乱，特别是糖尿病。本发明还提供了一种制备该化合物的方法，以及通过使用该化合物来预防或治疗代谢紊乱，特别是糖尿病的方法。

2. 发明申请

WO2011005052A8 NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 审中-公开
标题翻译：新颖的含有阿维菌素的咪唑烷四羧酰胺衍生物和包含其的药物组合物
公开(公告)号：WO2011005052A8
公开(公告)日：2012-02-02
申请号：PCT/KR2010004479
申请日：2010-07-09
申请人： GREEN CROSS CORP , LEE JINHWA , SEO HEE JEONG , KANG SUK YOUN , PARK EUN-JUNG , KIM MIN JU , LEE SUK HO , KIM JONG YUP , KIM JEONGMIN , JUNG MYUNG EUN , KIM HYUN JUNG , KIM MI-SOON , HAN HO KYUN , AHN KWANG WOO , LEE MIN WOO , LEE KI-NAM , PAE AE NIM , PARK WOO-KYU
发明人： LEE JINHWA , SEO HEE JEONG , KANG SUK YOUN , PARK EUN-JUNG , KIM MIN JU , LEE SUK HO , KIM JONG YUP , KIM JEONGMIN , JUNG MYUNG EUN , KIM HYUN JUNG , KIM MI-SOON , HAN HO KYUN , AHN KWANG WOO , LEE MIN WOO , LEE KI-NAM , PAE AE NIM , PARK WOO-KYU
IPC分类号： C07D403/12 , A61K31/497 , A61P25/24
CPC分类号： C07D417/14 , A61K31/496 , C07D233/88 , C07D401/12 , C07D403/06 , C07D405/04
摘要： A novel arylpiperazine-containing imidazole 4-carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating a depressive disorder are provided.
摘要翻译：提供了一种新的含有芳基哌嗪的咪唑4-甲酰胺衍生物或其药学上可接受的盐，以及包含其作为预防或治疗抑郁障碍的活性成分的药物组合物。

3. 发明申请

WO2011005052A3 NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 审中-公开
标题翻译：新的含芳基哌嗪的咪唑4-羧酰胺衍生物和包含它们的药物组合物
公开(公告)号：WO2011005052A3
公开(公告)日：2011-05-26
申请号：PCT/KR2010004479
申请日：2010-07-09
申请人： GREEN CROSS CORP , LEE JINHWA , SEO HEE JEONG , KANG SUK YOUN , PARK EUN-JUNG , KIM MIN JU , LEE SUK HO , KIM JONG YUP , KIM JEONGMIN , JUNG MYUNG EUN , KIM HYUN JUNG , KIM MI-SOON , HAN HO KYUN , AHN KWANG WOO , LEE MIN WOO , LEE KI-NAM , PAE AE NIM , PARK WOO-KYU
发明人： LEE JINHWA , SEO HEE JEONG , KANG SUK YOUN , PARK EUN-JUNG , KIM MIN JU , LEE SUK HO , KIM JONG YUP , KIM JEONGMIN , JUNG MYUNG EUN , KIM HYUN JUNG , KIM MI-SOON , HAN HO KYUN , AHN KWANG WOO , LEE MIN WOO , LEE KI-NAM , PAE AE NIM , PARK WOO-KYU
IPC分类号： C07D403/12 , A61K31/497 , A61P25/24
CPC分类号： C07D417/14 , A61K31/496 , C07D233/88 , C07D401/12 , C07D403/06 , C07D405/04
摘要： A novel arylpiperazine-containing imidazole 4-carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating a depressive disorder are provided.
摘要翻译：提供了一种新的含芳基哌嗪的咪唑-4-甲酰胺衍生物或其药学上可接受的盐，以及包含其作为用于预防或治疗抑郁症的活性成分的药物组合物。

4. 发明申请

WO2011059207A3 ARYLPIPERAZINE-CONTAINING PURINE DERIVATIVES AND USES THEREOF 审中-公开
标题翻译：含有阿维A的嘌呤衍生物及其用途
公开(公告)号：WO2011059207A3
公开(公告)日：2011-10-27
申请号：PCT/KR2010007804
申请日：2010-11-05
申请人： GREEN CROSS CORP , LEE JINHWA , PARK EUN-JUNG , KANG SUK YOUN , KONG YOUNGGYU , LEE JUNWON , KIM HYUN JUNG , JUNG MYUNG EUN , LEE KI-NAM , KIM JEONGMIN , PAE AE NIM , PARK WOO-KYU
发明人： LEE JINHWA , PARK EUN-JUNG , KANG SUK YOUN , KONG YOUNGGYU , LEE JUNWON , KIM HYUN JUNG , JUNG MYUNG EUN , LEE KI-NAM , KIM JEONGMIN , PAE AE NIM , PARK WOO-KYU
IPC分类号： C07D473/34 , A61K31/52 , A61P25/24 , C07D403/12
CPC分类号： C07D473/34
摘要： A novel arylpiperazine-containing purine derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating depressive disorders, are provided.
摘要翻译：提供了一种新的含有芳基哌嗪的嘌呤衍生物和包含其作为活性成分的药物组合物，其可用于预防或治疗抑郁障碍。

5. 发明公开

EP2714032A4 NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS 有权
标题翻译： NEW二苯甲烷衍生物作为SGLT2抑制剂的
公开(公告)号：EP2714032A4
公开(公告)日：2015-05-06
申请号：EP12793162
申请日：2012-06-01
申请人： GREEN CROSS CORP
发明人： CHOI SOONGYU , SONG KWANG-SEOP , LEE SUK HO , KIM MIN JU , SEO HEE JEONG , PARK EUN-JUNG , KONG YOUNGGYU , PARK SO OK , KANG HYUNKU , JUNG MYUNG EUN , LEE KINAM , KIM HYUN JUNG , LEE JUN SUNG , LEE MIN WOO , KIM MI-SOON , HONG DONG HO , KANG MISUK
IPC分类号： A61K31/357 , A61K31/015 , A61K31/343 , A61K31/35 , A61P3/00 , C07D309/10 , C07D405/10 , C07D405/14 , C07D407/04 , C07D407/10 , C07D407/14 , C07D409/04 , C07D409/10 , C07D411/10 , C07D413/04 , C07D413/10
CPC分类号： C07D309/10 , C07D405/10 , C07D405/14 , C07D407/04 , C07D407/10 , C07D407/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D411/10 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14
摘要： A compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney is disclosed. A pharmaceutical composition including the compound as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes is disclosed. A method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound is provided.

6. 发明申请

WO2009031806A3 MULTI-FUNCTIONAL OPTICAL FILM 审中-公开
标题翻译：多功能光学膜
公开(公告)号：WO2009031806A3
公开(公告)日：2009-05-07
申请号：PCT/KR2008005174
申请日：2008-09-03
申请人： KOLON INC , KIM KYUNG NAM , KIM HYUN JUNG , KIM SANG KYUN , KIM HYUN JIN , KANG CHUNG SEOCK
发明人： KIM KYUNG NAM , KIM HYUN JUNG , KIM SANG KYUN , KIM HYUN JIN , KANG CHUNG SEOCK
IPC分类号： G02B5/02
CPC分类号： G02F1/133615 , G02F1/133606 , G02F2001/133607
摘要： Disclosed is a multifunctional optical film for use in liquid crystal displays, which uniformly diffuses light emitted from a light guide plate and a diffusion plate, improves luminance, has a prism layer easily formed on a light diffusion layer, exhibits superior hiding performance, and decreases the loss of light, thus remarkably reducing the manufacturing process and costs thereof and realizing a thinner a liquid crystal display compared to a conventional construction composed of separate films, i.e., a light diffusion film and a prism film. The multifunctional optical film prevents the loss of light due to light interference, scattering or absorption caused by using a plurality of films and damage to the films.
摘要翻译：公开了一种用于液晶显示器的多功能光学膜，其均匀地漫射从导光板和漫射板发射的光，提高亮度，在光扩散层上容易形成棱镜层，表现出优异的遮盖性能，并且降低与由分散膜即光扩散膜和棱镜膜组成的传统结构相比，光的损失显着降低了制造工艺和成本，实现了更薄的液晶显示。多功能光学膜防止由于使用多个膜而引起的光干涉，散射或吸收而导致的光损失，并损坏膜。

7. 发明申请

WO2009048673A2 STOCHASTIC CONFINEMENT TO DETECT, MANIPULATE, AND UTILIZE MOLECULES AND ORGANISMS 审中-公开
标题翻译：检测，管理和利用分子和有机物的机密协定
公开(公告)号：WO2009048673A2
公开(公告)日：2009-04-16
申请号：PCT/US2008071374
申请日：2008-07-28
申请人： UNIV CHICAGO , BOEDICKER JAMES Q , ISMAGILOV RUSTEM F , KASTRUP CHRISTIAN , GERDTS CORY , HUYNH TOAN , KIM HYUN JUNG , RUNYON MATTHEW K , SHEN FENG
发明人： BOEDICKER JAMES Q , ISMAGILOV RUSTEM F , KASTRUP CHRISTIAN , GERDTS CORY , HUYNH TOAN , KIM HYUN JUNG , RUNYON MATTHEW K , SHEN FENG
IPC分类号： C12N1/20 , C12M1/00 , C12M1/14 , C12N1/38 , C12N11/04 , C12Q1/02
CPC分类号： C12M35/08 , C12M1/14 , C12M23/34 , C12M25/01 , C12N1/20 , C12N1/38 , C12N11/04 , C12P39/00 , C12Q1/18 , G01N33/542 , G01N33/54313
摘要： Methods of detecting organisms using stochastic confinement effects with microfluidic technologies are provided.
摘要翻译：提供了使用微流控技术的随机限制效应检测生物体的方法。

8. 发明申请

WO2012118799A3 CELL CULTURE SYSTEM 审中-公开
标题翻译：细胞培养系统
公开(公告)号：WO2012118799A3
公开(公告)日：2012-11-22
申请号：PCT/US2012026934
申请日：2012-02-28
申请人： HARVARD COLLEGE , INGBER DONALD E , KIM HYUN JUNG
发明人： INGBER DONALD E , KIM HYUN JUNG
IPC分类号： C12M3/02 , C12N1/14 , C12N1/20 , C12N5/071
CPC分类号： C12N5/0697 , C12M21/08 , C12M23/20 , C12M23/26 , C12M23/34 , C12M23/38 , C12M25/02 , C12M27/02 , C12M29/04 , C12M29/06 , C12M35/04 , C12M35/08 , C12M41/12 , C12M41/26 , C12M41/40 , C12M41/44 , C12N1/14 , C12N1/20 , C12N5/0679 , C12N5/068 , C12N5/0696
摘要： The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in vitro. The cells, tissues and/or organoids cultured according to the methods and systems described herein can mimic or reproduce natural intestinal epithelial structures and behavior as well as support co-culture of intestinal microflora.
摘要翻译：本文描述的本发明的实施方案涉及用于在体外培养和/或维持肠细胞，组织和/或类器官的系统和方法。根据本文所述的方法和系统培养的细胞，组织和/或器官可以模拟或再现天然肠上皮结构和行为以及支持肠微生物群落的共培养。

9. 发明申请

WO2009015390A3 CO-INCUATING CONFINED MICROBIAL COMMUNITIES 审中-公开
标题翻译：共同确定的微生物群落
公开(公告)号：WO2009015390A3
公开(公告)日：2009-04-23
申请号：PCT/US2008071370
申请日：2008-07-28
申请人： UNIV CHICAGO , BOEDICKER JAMES Q , ISMAGILOV RUSTEM F , KIM HYUN JUNG
发明人： BOEDICKER JAMES Q , ISMAGILOV RUSTEM F , KIM HYUN JUNG
IPC分类号： C12N1/20 , C12M1/00 , C12M1/14 , C12N1/38 , C12N11/04 , C12Q1/02
CPC分类号： C12M35/08 , C12M1/14 , C12M23/34 , C12M25/01 , C12N1/20 , C12N1/38 , C12N11/04 , C12P39/00 , C12Q1/18 , G01N33/542 , G01N33/54313
摘要： This invention provides devices and methods that enable co- incubation of microorganisms. Also provided are methods of making such devices for co-incubation of microorganisms, and various applications of such devices.
摘要翻译：本发明提供了能够共同孵育微生物的装置和方法。还提供了制造用于微生物共孵育的装置以及这种装置的各种应用的方法。

10. 发明申请

WO2009104868A3 DEODORIZATION DEVICE OF COOKING APPARATUS AND COOKING APPARATUS INCLUDING THE DEODORIZATION DEVICE 审中-公开
标题翻译：烹饪设备的除臭装置和包括除臭装置的烹饪装置
公开(公告)号：WO2009104868A3
公开(公告)日：2009-10-29
申请号：PCT/KR2008007858
申请日：2008-12-31
申请人： LG ELECTRONICS INC , HU JIN YUL , CHOI HEUNG SHIK , KIM HYUN JUNG
发明人： HU JIN YUL , CHOI HEUNG SHIK , KIM HYUN JUNG
IPC分类号： F24C15/20
CPC分类号： A61L9/22
摘要： A deodorization device of a cooking apparatus and a cooking apparatus having the deodorization device are disclosed. Because a discharge space is formed between first and second discharging units and air containing an odorant material entirely passes through the discharge space, the odorant material in the discharge space can be effectively removed. In addition, because the second discharging unit includes a plurality of electrode protrusions protrusively formed to be in contact with the first discharging unit, strong plasma can be generated in the vicinity of the electrode protrusions, so the deodorization effect can be improved. Moreover, because the plurality of electrode protrusions and the first discharging unit are disposed to be separated from each other, a phenomenon that end portions of the electrode protrusions are abraded when high temperature plasma is generated can be minimized, and thus, the life span can be lengthened.
摘要翻译：公开了一种烹饪设备的除臭装置和具有该除臭装置的烹饪设备。因为在第一和第二排放单元之间形成排放空间并且含有加味剂材料的空气完全通过排放空间，所以可以有效地去除排放空间中的加味剂材料。另外，因为第二放电单元包括突起地形成为与第一放电单元接触的多个电极突起，所以可以在电极突起附近产生强等离子体，因此可以改善除臭效果。此外，因为多个电极突起和第一放电单元被设置为彼此分离，所以当产生高温等离子体时电极突起的端部被磨损的现象可以被最小化，并且因此寿命可以加长。

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