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    • 4. 发明专利
    • Frame with integral sewing cuff for prosthetic valves
    • AU2018282323B2
    • 2020-08-06
    • AU2018282323
    • 2018-12-19
    • GORE & ASS
    • GASSLER PAUL D
    • A61F2/24
    • Described embodiments are related to a method of making a frame assembly for a prosthetic valve, comprising: placing a first layer of film about a mandrel; placing a fabric including a plurality of pores over the first layer of film; providing a frame having a tubular shape, the frame having a frame inside surface and a frame outside surface, the frame defining a frame base and a plurality of leaflet windows; placing the frame over the fabric such that the fabric is situated between the frame and the first layer of film, and such that the frame inside surface contacts the fabric; everting the fabric over the frame outside surface such that the fabric defines a fabric frame portion, and such that the fabric defines a fold that extends from the fabric frame portion to define a sewing cuff; placing a second layer of film over the fabric frame portion; and coupling the fabric frame portion to one or more of the first and second layers of film such that an elastomer of one or more of the first and second layers of film is present in the fabric pores of the fabric frame portion but not in the fabric pores of the sewing cuff. 10948579_1 (GHMaters) P105095.AU.1 s 142 K-160