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    • 1. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008110584A3
    • 2008-11-27
    • PCT/EP2008052967
    • 2008-03-12
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASELLIMAN DAVID VINCENTKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • ANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASELLIMAN DAVID VINCENTKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • A61M15/00
    • A61M15/009A61M15/0026A61M15/0075A61M15/0091A61M15/0096A61M2205/6081G06M1/04G06M1/083
    • One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; an actuation counter; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to both move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism and also to actuate the actuation counter until a pre-determined threshold force is overcome.
    • 一方面提供了一种药物分配器装置,其包括壳体; 从壳体延伸,用于插入患者体腔中的出口; 所述药物排出装置具有纵向轴线并且包括用于储存待分配的药物制剂的容器,排出机构和从容器排出药物制剂到排出口的排出通道 ; 连接到所述容器,连接到所述排放装置的容器套环; 连接到所述容器套环并且能够沿着所述药物排放装置的纵向轴线相对于所述容器套环移动;传递元件,所述传递元件包括致动部分; 提供给所述壳体的至少一个手指可操作构件,所述至少一个手指可操作构件可移动以向所述传递元件的所述致动部分施加力以沿着所述纵向轴线在第一方向上移动所述传递元件; 将所述容器套环与所述传递元件联接;偏置机构,用于在所述传递元件沿着所述纵向轴线在所述第一方向上移动时存储偏置能量; 一个致动计数器; 并向容器套环提供预加载机构以防止偏置能量传递到容器套环以使药物排放装置沿第一方向沿纵向轴线移动以致动排放机构并且还致动致动计数器 直到克服预定的阈值力。
    • 2. 发明申请
    • DRUG DISPENSER
    • 药物分配器
    • WO2008023019A3
    • 2008-05-29
    • PCT/EP2007058679
    • 2007-08-21
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • ANDERSON GREGOR JOHN MCLENNANCROSBY GARY THOMASKELLY ANDREW MICHAELTEUCHER MARK DIGBYWEST JAMES ANTHONY
    • B05B11/00A61M15/00
    • A61M15/009A61M15/0025A61M15/0075A61M15/0081A61M15/0096A61M2205/276A61M2205/8281B65D83/16
    • There is provided a drug dispenser device (1) comprising a housing (10a, 10b, 12), extending from the housing, an outlet (16) for insertion into a body-cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger (20a, 20b) operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction, linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome.
    • 提供了一种药物分配器装置(1),其包括从壳体延伸的壳体(10a,10b,12),用于插入患者体腔的出口(16); 提供给壳体并相对于其可移动的药物排出装置,具有纵向轴线并包括用于储存待分配的药物制剂的容器,排出机构和来自容器的排出通道,用于将药物制剂排出到出口 ; 连接到药物排出装置,容器衣领; 连接到所述容器套环并且沿着所述药物排出装置的纵向轴线可相对于其移动;转移元件,所述转移元件包括致动部分; 提供给壳体的至少一个手指(20a,20b)可操作构件可移动以对传递元件的致动部分施加力,以沿第一方向沿着纵向轴线移动传递元件,将容器环与传送件 元件,偏置机构,用于在第一方向沿着纵向轴线移动传递元件时存储偏置能量; 并且提供给所述容器套环,所述预加载机构用于防止所述偏置能量转移到所述容器套环,以沿所述纵向轴线沿所述第一方向移动所述药物排出装置,以启动所述排放机构,直到预定的阈值力为 克服。
    • 9. 发明申请
    • MEDICAMENT DISPENSER
    • 药物分配器
    • WO2007068900A3
    • 2007-07-26
    • PCT/GB2006004623
    • 2006-12-11
    • GLAXO GROUP LTDANDERSON GREGOR JOHN MCLENNANDAVIES MICHAEL BIRSHAHAILEY MARK ANDREWPALMER MARK GREGORYWALKER RICHARD IAN
    • ANDERSON GREGOR JOHN MCLENNANDAVIES MICHAEL BIRSHAHAILEY MARK ANDREWPALMER MARK GREGORYWALKER RICHARD IAN
    • A61M15/00
    • A61M15/0045A61M15/0026A61M15/0043A61M15/0051A61M15/0055A61M15/007A61M15/0075A61M2202/064A61M2205/12
    • There is provided a medicament dispenser device for the delivery of medicament powder from an open blister pocket (404a,b) of at least one blister pack (400a,b). The dispenser device comprises a housing (420) having an air inlet (470); enclosed by the housing, a dispensing mechanism (440, 448a,b) for the dispensing of medicament powder from an open blister pocket; and associated with the dispensing mechanism and in communication with the air inlet, a manifold (450). The manifold comprises a body, the body defining a chimney (452) having a chimney inlet (453) and a chimney exit (454a,b) for directing airflow (483) from said chimney inlet to said chimney exit; the body further defining a chamber (460) having a chamber inlet (473a,b) and a chamber exit (474), wherein the chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof. In use, the airflow is drawn into the chimney of the manifold solely through the air inlet provided to the housing.
    • 提供了一种用于从至少一个泡罩包装(400a,b)的开口泡罩袋(404a,b)输送药物粉末的药物分配器装置。 分配器装置包括具有空气入口(470)的壳体(420); 由外壳封闭的分配机构(440,448a,b),用于从开口泡罩袋中分配药物粉末; 并且与分配机构相关联并且与空气入口连通,歧管(450)。 所述歧管包括主体,所述主体限定具有烟囱入口(453)和烟囱出口(454a,b)的烟囱(452),烟囱出口用于将气流(483)从所述烟囱入口引导至所述烟囱出口; 所述主体进一步限定具有腔室入口(473a,b)和腔室出口(474)的腔室(460),其中所述烟囱出口和所述腔室入口彼此并排设置,使得当所述开口泡罩袋 所述泡罩包装定位在其附近,所述气流可以从烟囱出口通过敞开的泡罩袋引导至腔室入口,以夹带所述药物粉末并使其能够运输。 在使用中,气流仅通过提供给壳体的进气口被吸入歧管的烟囱中。