专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2021081420A2 CONJUGATES AND METHODS FOR TREATING ACROMEGALY 审中-公开
公开(公告)号：WO2021081420A2
公开(公告)日：2021-04-29
申请号：PCT/US2020/057185
申请日：2020-10-23
申请人： GENEVANT SCIENCES GMBH , KONDRATOWICZ, Drew , HEYES, James , HOLLAND, Richard J. , ESAU, Christine , MCCLINTOCK, Kevin , PASETKA, Chris Justin , WOOD, Mark , MARTIN, Alan D. , SCHWARZ, Margrit , CROWE, David , TYLER, Steven
发明人： KONDRATOWICZ, Drew , HEYES, James , HOLLAND, Richard J. , ESAU, Christine , MCCLINTOCK, Kevin , PASETKA, Chris Justin , WOOD, Mark , MARTIN, Alan D. , SCHWARZ, Margrit , CROWE, David , TYLER, Steven
IPC分类号： C12N15/87 , A61K31/7072 , A61K31/7076 , A61K31/708 , A61K31/7088 , A61K31/7115 , A61K31/712 , A61K31/713 , A61P5/00 , C07K9/001
摘要： Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. He conjugates are useful to treat certain diseases, such as acromegaly.

2. 发明申请

WO2021113820A1 CONJUGATES AND METHODS FOR TREATING LIVER FIBROSIS 审中-公开
公开(公告)号：WO2021113820A1
公开(公告)日：2021-06-10
申请号：PCT/US2020/063617
申请日：2020-12-07
申请人： GENEVANT SCIENCES GMBH , HEYES, James , HOLLAND, Richard J. , WOOD, Mark , MARTIN, Alan D. , ESAU, Christine , SCHWARZ, Margrit , YE, Xin , LI, Alice , PASETKA, Chris Justin , CROWE, David , TYLER, Steven
发明人： HEYES, James , HOLLAND, Richard J. , WOOD, Mark , MARTIN, Alan D. , ESAU, Christine , SCHWARZ, Margrit , YE, Xin , LI, Alice , PASETKA, Chris Justin , CROWE, David , TYLER, Steven
IPC分类号： A61K38/19 , C07K16/28 , A61K38/17
摘要： Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to treat certain diseases, such as liver fibrosis, e.g., in the setting of NASH or ASH.

3. 发明公开

EP4069276A1 CONJUGATES AND METHODS FOR TREATING LIVER FIBROSIS 审中-实审转让
公开(公告)号：EP4069276A1
公开(公告)日：2022-10-12
申请号：EP20896461.9
申请日：2020-12-07
申请人： Genevant Sciences GmbH
发明人： HEYES, James , HOLLAND, Richard J. , WOOD, Mark , MARTIN, Alan D. , ESAU, Christine , SCHWARZ, Margrit , YE, Xin , LI, Alice Hoy Lam , PASETKA, Christopher Justin , CROWE, David , TYLER, Steven
IPC分类号： A61K38/19 , C07K16/28 , A61K38/17

5. 发明申请

WO2006090150A1 PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS ROSIGLITAZONE 审中-公开
标题翻译：包含非晶罗西他他的药物组合物
公开(公告)号：WO2006090150A1
公开(公告)日：2006-08-31
申请号：PCT/GB2006/000632
申请日：2006-02-23
申请人： SMITHKLINE BEECHAM CORPORATION , CRAIG, Andrew, Simon , CROWE, David , HO, Tim, Chien, Ting , MILLAN, Michael, John
发明人： CRAIG, Andrew, Simon , CROWE, David , HO, Tim, Chien, Ting , MILLAN, Michael, John
IPC分类号： A61K31/4439 , A61P3/10 , A61K9/14
CPC分类号： A61K9/146 , A61K9/5138 , A61K9/5161 , A61K9/5192 , A61K9/70 , A61K31/00 , A61K31/4439 , D01D5/003 , D01F1/10
摘要： The present invention is directed to use of electrospinning, i.e. the process of making polymer nanofibers from either a solution or melt under electrical forces, to prepare stable, solid dispersions of amorphous drugs in polymer nanofibers. The present invention is also directed to the process of making solid dispersions of amorphous forms and compositions of rosiglitazone and its pharmaceutically acceptable salts.
摘要翻译：本发明涉及静电纺丝的应用，即在电力下由溶液或熔体制备聚合物纳米纤维的方法，以在聚合物纳米纤维中制备稳定的无定形药物的固体分散体。本发明还涉及制备无定形形式的固体分散体和罗格列酮组合物及其药学上可接受的盐的方法。

6. 发明申请

WO2014018237A3 INTERFACING WITH MULTIPLE OBJECTS 审中-公开
标题翻译：与多个对象交互
公开(公告)号：WO2014018237A3
公开(公告)日：2014-01-30
申请号：PCT/US2013/049238
申请日：2013-07-03
申请人： TUCSON EMBEDDED SYSTEMS , CROM, Elden , CROWE, David , KENJORA, Paul , MULHOLLAND, Sean
发明人： CROM, Elden , CROWE, David , KENJORA, Paul , MULHOLLAND, Sean
IPC分类号： G06F3/00
摘要： A computer implemented method and apparatus is presented for communicating between a platform and multiple objects, where the objects comprise a set of parameters and an object- specific interface protocol, where at least one of the object-specific interface protocols differs from at least one other object- specific interface protocol. The method includes identifying the objects and creating multiple nonobject-specific data structures, where at least one of the nonobject-specific data structures can engage each parameter of each set of parameters. The method further includes transforming, using the plurality of nonobject-specific data structures created, the object-specific interface protocols into a single nonobject-specific interface protocol for communicating between the platform and the objects.
摘要翻译：提出了一种用于在平台和多个对象之间进行通信的计算机实现的方法和装置，其中对象包括一组参数和对象特定接口协议，其中至少一个对象特定接口协议与至少一个其他对象专用接口协议不同。该方法包括识别对象并创建多个非对象特定数据结构，其中至少一个非对象特定数据结构可以参与每组参数的每个参数。该方法还包括使用所创建的多个非特定于对象的数据结构将特定于对象的接口协议转换为用于平台与对象之间的通信的单个非特定于对象的接口协议。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式