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    • 7. 发明申请
    • METHOD FOR DETECTING CONCENTRATION OF ANTIBODY OR FUSION PROTEIN
    • 检测抗体或融合蛋白浓度的方法
    • WO2013162456A1
    • 2013-10-31
    • PCT/SE2013/050449
    • 2013-04-24
    • GENERAL ELECTRIC COMPANYGE HEALTHCARE BIO-SCIENCES AB
    • CHEN, LinHOCHLEITNER, KlausHOU, RongLU, LianghuaYANG, Jianjun
    • G01N33/558
    • G01N33/558G01N2333/525
    • A method comprises: providing a test strip having a sample portion, a conjugation portion comprising a control protein bindable to a fragment crystallizable (Fc) portion of an antibody or a fusion protein and a label conjugated with the control protein, a detection portion comprising an antigen specific for the antibody or the fusion protein, and a control portion comprising a control antibody of the control protein; contacting a sample solution comprising the antibody or the fusion protein with the sample portion; allowing the sample solution to migrate from the sample portion through the control portion; detecting an intensity of a signal of the detection portion; and determining the concentration of the antibody or the fusion protein in the sample solution using a formula in which the concentration of the antibody or the fusion protein is a function of the intensity of the signal.
    • 一种方法包括:提供具有样品部分的测试条,包含可与抗体或融合蛋白的可结晶(Fc)部分结合的对照蛋白的缀合部分和与对照蛋白质结合的标记,检测部分包含 抗体或融合蛋白特异的抗原,以及包含对照蛋白的对照抗体的对照部分; 使包含抗体或融合蛋白的样品溶液与样品部分接触; 允许样品溶液从样品部分迁移通过控制部分; 检测所述检测部分的信号的强度; 并使用其中抗体或融合蛋白的浓度是信号强度的函数的公式确定样品溶液中抗体或融合蛋白的浓度。
    • 9. 发明申请
    • METHOD AND SYSTEM FOR FORMING POLYMER MICROPARTICLES
    • 形成聚合物微粒的方法和系统
    • WO2018001865A1
    • 2018-01-04
    • PCT/EP2017/065426
    • 2017-06-22
    • GENERAL ELECTRIC COMPANYGE HEALTHCARE BIO-SCIENCES AB
    • CHEN, LinGAO, JieHUANG, Qiongqiong
    • B01J13/04
    • A method for forming polymer microparticles is disclosed. The method comprises spraying a liquid comprising a thermally-gelling polymer from a first orifice of a nozzle into air to form gelled microparticles, and collecting the gelled microparticles with a collecting device. The nozzle is positioned to have a central axis of the first orifice at a tilt angle in a range from about 10 degrees to about 170 degrees relative to a direction of gravity. The collecting device comprises at least two collecting units at different distances from the first orifice of the nozzle in a horizontal direction perpendicular to the direction of gravity. Each of the collecting unit is loaded with a liquid collecting medium. A system for forming polymer microparticles is also disclosed.
    • 公开了形成聚合物微粒的方法。 该方法包括将包含热凝胶聚合物的液体从喷嘴的第一孔口喷射到空气中以形成凝胶化的微粒,并且用收集装置收集凝胶化的微粒。 喷嘴被定位成使第一孔的中心轴线相对于重力方向处于约10度至约170度的范围内的倾斜角度。 该收集装置包括至少两个收集单元,该至少两个收集单元在垂直于重力方向的水平方向上与喷嘴的第一孔口不同距离。 每个收集单元装有液体收集介质。 还公开了用于形成聚合物微粒的系统。