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1. 发明申请

WO2004009054A3 ENCAPSULATION OF SENSITIVE COMPONENTS USING PRE-EMULSIFICATION 审中-公开
标题翻译：使用预实验的敏感组件的封装
公开(公告)号：WO2004009054A3
公开(公告)日：2004-05-06
申请号：PCT/US0319028
申请日：2003-06-17
申请人： GEN MILLS INC , VAN LENGERICH BERNHARD H , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS M
发明人： VAN LENGERICH BERNHARD H , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS M
IPC分类号： A23L1/00 , A23L1/30
CPC分类号： A23L33/115 , A23P10/30 , Y10T428/2984
摘要： A stabilized emulsion is employed to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component to form an emulsion. An antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a film-softening component or plasticizer for the film-forming component may be included in the emulsion. The emulsion is stabilized by subjecting it to homogenization. The pellets are produced by first reducing the water content of the stabilized emulsion so that the film-forming component forms a film around the oil droplets and encapsulates the encapsulant. In embodiments of the invention, the water content of the homogenized emulsion may be reduced by spray drying to produce a powder. In other embodiments of the invention, after homogenization, the water content of the emulsion may be reduced by admixing the emulsion with at least one matrix material to thereby encapsulate the film-coated oil droplets within the matrix material. After the water content of the emulsion is reduced, a protective coating is applied on the film-coated oil droplets to obtain pellets.
摘要翻译：使用稳定化的乳液来制备搁置稳定的，控制释放的，离散的，固体颗粒或颗粒，其含有包封和/或嵌入的组分，例如容易氧化的组分，例如ω-3脂肪酸。将含有溶解和/或分散在油中的活性敏感密封剂的油包封剂组分与水性组分和成膜组分混合以形成乳液。用于防止活性敏感性密封剂氧化的抗氧化剂，以及用于成膜组分的薄膜软化组分或增塑剂可以包括在乳液中。通过使乳液均匀化使乳液稳定。通过首先降低稳定的乳液的含水量使得成膜组分在油滴周围形成膜并封装密封剂来制备颗粒。在本发明的实施方案中，均匀乳液的含水量可以通过喷雾干燥来降低以产生粉末。在本发明的其它实施方案中，在均化之后，可以通过将乳液与至少一种基质材料混合从而将包膜的油滴包封在基质材料内，从而降低乳液的含水量。在乳液的含水量减少之后，在涂覆有油滴的油滴上施加保护涂层以获得颗粒。

2. 发明专利

DE60329847D1 未知
公开(公告)号：DE60329847D1
公开(公告)日：2009-12-10
申请号：DE60329847
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： VAN LENGERICH BERNHARD H , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS M
IPC分类号： A23L1/30 , A23L1/00
摘要： A stabilized emulsion is employed to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component to form an emulsion. An antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a film-softening component or plasticizer for the film-forming component may be included in the emulsion. The emulsion is stabilized by subjecting it to homogenization. The pellets are produced by first reducing the water content of the stabilized emulsion so that the film-forming component forms a film around the oil droplets and encapsulates the encapsulant. In embodiments of the invention, the water content of the homogenized emulsion may be reduced by spray-drying to produce a powder. In other embodiments of the invention, after homogenization, the water content of the emulsion may be reduced by admixing the emulsion with at least one matrix material to thereby encapsulate the film-coated oil droplets within the matrix material. After the water content of the emulsion is reduced, a protective coating is applied on the film-coated oil droplets to obtain pellets.

3. 发明专利

CA2493519C ENCAPSULATION OF SENSITIVE COMPONENTS USING PRE-EMULSIFICATION 未知
公开(公告)号：CA2493519C
公开(公告)日：2010-08-24
申请号：CA2493519
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： VAN LENGERICH BERNHARD H , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS M
IPC分类号： A23L1/30 , A23L1/00
摘要： A stabilized emulsion is employed to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component to form an emulsion. An antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a film-softening component or plasticizer for the film-forming component may be included in the emulsion. The emulsion is stabilized by subjecting it to homogenization. The pellets are produced by first reducing the water content of the stabilized emulsion so that the film-forming component forms a film around the oil droplets and encapsulates the encapsulant. In embodiments of the invention, the water content of the homogenized emulsion may be reduced by spray drying to produce a powder. In other embodiments of the invention, after homogenization, the water content of the emulsion may be reduced by admixing the emulsion with at least one matrix material to thereby encapsulate the film-coated oil droplets within the matrix material. After the water content of the emulsion is reduced, a protective coating is applied on the film-coated oil droplets to obtain pellets.

4. 发明专利

ES2334993T3 ENCAPSULAMIENTO DE COMPONENTES SENSIBLES MEDIANTE PRE-EMULSIONAMIENTO. 未知
公开(公告)号：ES2334993T3
公开(公告)日：2010-03-18
申请号：ES03765446
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： VAN LENGERICH BERNHARD H , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS M
IPC分类号： A23L1/30 , A23L1/00
摘要： Un método para encapsular un encapsulante, que comprende mezclar un componente oleoso que comprende un encapsulante, con un componente acuoso y un componente formador de película para formar una emulsión, someter la emulsión a homogeneización para obtener una emulsión de aceite en agua que comprende gotitas de aceite en la que las gotitas de aceite comprenden el encapsulante y tienen un diámetro menor que alrededor de 50 micrómetros, y el componente formador de película rodea a las gotitas de aceite, reducir el contenido de agua de la emulsión de forma que el componente formador de película forme una película alrededor de las gotitas de aceite y encapsule a dicho encapsulante, en el que el contenido de agua de la emulsión se reduce mezclando la emulsión con un material de matriz para formar una pasta, para encapsular de ese modo a dichas gotitas de aceite revestidas con la película dentro de dicho material de matriz, y en el que dicho material de matriz comprende un material de matriz plastificable, siendo plastificado dicho material de matriz mediante dicho componente acuoso para encapsular de ese modo a dichas gotitas de aceite revestidas con la película dentro de dicho material de matriz plastificado.

5. 发明专利

DK1526782T3 Indkapsling af følsomme komponenter ved brug af pre-emulgering 未知
公开(公告)号：DK1526782T3
公开(公告)日：2010-03-01
申请号：DK03765446
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： VAN LENGERICH BERNHARD H , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS M
IPC分类号： A23L1/30 , A23L1/00

6. 发明专利

AT446684T 未知
公开(公告)号：AT446684T
公开(公告)日：2009-11-15
申请号：AT03765446
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： VAN LENGERICH BERNHARD , LEUNG LILY , ROBIE STEVEN , LAKKIS JAMILEH , KANG YOUNG , JARL THOMAS
IPC分类号： A23L1/30 , A23L1/00
摘要： A stabilized emulsion is employed to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component to form an emulsion. An antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a film-softening component or plasticizer for the film-forming component may be included in the emulsion. The emulsion is stabilized by subjecting it to homogenization. The pellets are produced by first reducing the water content of the stabilized emulsion so that the film-forming component forms a film around the oil droplets and encapsulates the encapsulant. In embodiments of the invention, the water content of the homogenized emulsion may be reduced by spray-drying to produce a powder. In other embodiments of the invention, after homogenization, the water content of the emulsion may be reduced by admixing the emulsion with at least one matrix material to thereby encapsulate the film-coated oil droplets within the matrix material. After the water content of the emulsion is reduced, a protective coating is applied on the film-coated oil droplets to obtain pellets.

7. 发明专利

AU2003243612A1 ENCAPSULATION OF SENSITIVE COMPONENTS USING PRE-EMULSIFICATION 未知
公开(公告)号：AU2003243612A1
公开(公告)日：2004-02-09
申请号：AU2003243612
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： KANG YOUNG , JARL THOMAS M , LENGERICH BERNHARD H VAN , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH
IPC分类号： A23L1/00 , A23L1/30 , A61K9/00
摘要： A stabilized emulsion is employed to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component to form an emulsion. An antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a film-softening component or plasticizer for the film-forming component may be included in the emulsion. The emulsion is stabilized by subjecting it to homogenization. The pellets are produced by first reducing the water content of the stabilized emulsion so that the film-forming component forms a film around the oil droplets and encapsulates the encapsulant. In embodiments of the invention, the water content of the homogenized emulsion may be reduced by spray-drying to produce a powder. In other embodiments of the invention, after homogenization, the water content of the emulsion may be reduced by admixing the emulsion with at least one matrix material to thereby encapsulate the film-coated oil droplets within the matrix material. After the water content of the emulsion is reduced, a protective coating is applied on the film-coated oil droplets to obtain pellets.

8. 发明专利

PT1526782E ENCAPSULAÇÃO DE COMPONENTES SENSÍVEIS USANDO A PRÉ- EMULSIFICAÇÃO 未知
公开(公告)号：PT1526782E
公开(公告)日：2010-01-20
申请号：PT03765446
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： JARL THOMAS M , LENGERICH BERNHARD H VAN , LEUNG LILY , ROBIE STEVEN C , LAKKIS JAMILEH , KANG YOUNG
IPC分类号： A23L1/00 , A23L1/30

9. 发明专利

CA2493519A1 ENCAPSULATION OF SENSITIVE COMPONENTS USING PRE-EMULSIFICATION 未知
公开(公告)号：CA2493519A1
公开(公告)日：2004-01-29
申请号：CA2493519
申请日：2003-06-17
申请人： GEN MILLS INC
发明人： VAN LENGERICH BERNHARD H , KANG YOUNG , JARL THOMAS M , LAKKIS JAMILEH , ROBIE STEVEN C , LEUNG LILY
IPC分类号： A23L1/00 , A23L1/30
摘要： A stabilized emulsion is employed to produce shelf stable, controlled releas e, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitiv e encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component to form an emulsion. An antioxidant f or prevention of oxidation of the active, sensitive encapsulant, and a film- softening component or plasticizer for the film-forming component may be included in the emulsion. The emulsion is stabilized by subjecting it to homogenization. The pellets are produced by first reducing the water content of the stabilized emulsion so that the film-forming component forms a film around the oil droplets and encapsulates the encapsulant. In embodiments of the invention, the water content of the homogenized emulsion may be reduced by spray drying to produce a powder. In other embodiments of the invention, aft er homogenization, the water content of the emulsion may be reduced by admixing the emulsion with at least one matrix material to thereby encapsulate the fi lm- coated oil droplets within the matrix material. After the water content of t he emulsion is reduced, a protective coating is applied on the film-coated oil droplets to obtain pellets.

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