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1. 发明申请

WO2007120818A3 COMPOSITIONS AND METHODS FOR INHIBITING ADHESIONS 审中-公开
标题翻译：用于抑制粘连的组合物和方法
公开(公告)号：WO2007120818A3
公开(公告)日：2008-11-06
申请号：PCT/US2007009121
申请日：2007-04-12
申请人： GEN HOSPITAL CORP , DU PONT , MASSACHUSETTS GEN HOSPITAL , YEO YOON , ITO TAICHI , LANGER ROBERT S , KOHANE DANIEL S , KODOKIAN GEORGE KEVORK
发明人： YEO YOON , ITO TAICHI , LANGER ROBERT S , KOHANE DANIEL S , KODOKIAN GEORGE KEVORK
IPC分类号： A61F13/00 , A01N43/04 , A61F2/00 , A61K31/715
CPC分类号： A61L31/145 , A61L31/041 , A61L31/129 , C08J3/075 , C08J3/246 , C08J2301/28 , C08J2305/02 , C08J2305/08 , C08L1/28 , C08L5/08 , C08L5/02
摘要： The present invention provides compositions and methods for inhibiting adhesions. The methods involve administering solutions containing hydrogel precursors such as polysaccharide derivatives, e.g., derivatives of hyaluronic acid, cellulose, or dextran, to a subject at a site where adhesions may form, e.g., as a consequence of surgery, injury, or infection. The hydrogel precursors, e.g., polysaccharide derivatives, become crosslinked following their administration to form a hydrogel that maintains tissue separation. In certain embodiments of the invention one or both solutions contains particles, e.g., polymeric nanoparticles or microparticles, so that a composite hydrogel containing the particles is formed. The solution(s), particle(s), or both, may contain a biologically active agent such as an agent that contributes to inhibiting adhesions. The biologically active agent may be covalently attached to a hydrogel precursor.
摘要翻译：本发明提供抑制粘连的组合物和方法。所述方法包括将诸如多糖衍生物例如透明质酸衍生物，纤维素或葡聚糖的水凝胶前体施用于在可能形成粘连的部位（例如作为手术，损伤或感染的结果）的受试者的溶液。水凝胶前体，例如多糖衍生物在其施用后变得交联以形成维持组织分离的水凝胶。在本发明的某些实施方案中，一种或两种溶液含有颗粒，例如聚合物纳米颗粒或微粒，从而形成含有颗粒的复合水凝胶。溶液，颗粒或两者都可以含有生物活性剂，例如有助于抑制粘连的试剂。生物活性剂可以共价连接到水凝胶前体。

2. 发明申请

WO2007120818A9 COMPOSITIONS AND METHODS FOR INHIBITING ADHESIONS 审中-公开
标题翻译：用于抑制粘连的组合物和方法
公开(公告)号：WO2007120818A9
公开(公告)日：2007-12-13
申请号：PCT/US2007009121
申请日：2007-04-12
申请人： MASSACHUSETTS INST TECHNOLOGY , DUPONT CO , MASSACHUSETTS GEN HOSPITAL , YEO YOON , ITO TAICHI , LANGER ROBERT S , KOHANE DANIEL S , KODOKIAN GEORGE KEVORK
发明人： YEO YOON , ITO TAICHI , LANGER ROBERT S , KOHANE DANIEL S , KODOKIAN GEORGE KEVORK
IPC分类号： A61F2/02
CPC分类号： A61L31/145 , A61L31/041 , A61L31/129 , C08J3/075 , C08J3/246 , C08J2301/28 , C08J2305/02 , C08J2305/08 , C08L1/28 , C08L5/08 , C08L5/02
摘要： The present invention provides compositions and methods for inhibiting adhesions. The methods involve administering solutions containing hydrogel precursors such as polysaccharide derivatives, e.g., derivatives of hyaluronic acid, cellulose, or dextran, to a subject at a site where adhesions may form, e.g., as a consequence of surgery, injury, or infection. The hydrogel precursors, e.g., polysaccharide derivatives, become crosslinked following their administration to form a hydrogel that maintains tissue separation. In certain embodiments of the invention one or both solutions contains particles, e.g., polymeric nanoparticles or microparticles, so that a composite hydrogel containing the particles is formed. The solution(s), particle(s), or both, may contain a biologically active agent such as an agent that contributes to inhibiting adhesions. The biologically active agent may be covalently attached to a hydrogel precursor.
摘要翻译：本发明提供抑制粘连的组合物和方法。所述方法包括将诸如多糖衍生物例如透明质酸衍生物，纤维素或葡聚糖的水凝胶前体施用于受试者在可能形成粘连的部位（例如手术，损伤或感染的结果）的溶液。水凝胶前体，例如多糖衍生物在其施用后变得交联以形成维持组织分离的水凝胶。在本发明的某些实施方案中，一种或两种溶液含有颗粒，例如聚合物纳米颗粒或微粒，从而形成含有颗粒的复合水凝胶。溶液，颗粒或两者都可以含有生物活性剂，例如有助于抑制粘连的试剂。生物活性剂可以共价连接到水凝胶前体。

3. 发明公开

EP2010117A4 COMPOSITIONS AND METHODS FOR INHIBITING ADHESIONS 审中-公开
标题翻译：组合物和方法粘附抑制
公开(公告)号：EP2010117A4
公开(公告)日：2010-12-01
申请号：EP07755404
申请日：2007-04-12
申请人： MASSACHUSETTS INST TECHNOLOGY , DU PONT , GEN HOSPITAL CORP
发明人： YEO YOON , ITO TAICHI , LANGER ROBERT S , KOHANE DANIEL S , KODOKIAN GEORGE KEVORK
IPC分类号： A61F13/00 , A01N43/04 , A61F2/00 , A61K31/715 , C08J3/075 , C08J3/24
CPC分类号： A61L31/145 , A61L31/041 , A61L31/129 , C08J3/075 , C08J3/246 , C08J2301/28 , C08J2305/02 , C08J2305/08 , C08L1/28 , C08L5/08 , C08L5/02

4. 发明申请

WO0048840A8 IMAGE FORMING DEVICE 审中-公开
标题翻译：图像形成装置
公开(公告)号：WO0048840A8
公开(公告)日：2000-11-02
申请号：PCT/JP0000910
申请日：2000-02-17
申请人： MATSUSHITA ELECTRIC IND CO LTD , ARRAY PRINTERS AB , ITO TAICHI , KUMON AKIRA , OGAWA KATSUTOSHI , FUKANO AKIRA
发明人： ITO TAICHI , KUMON AKIRA , OGAWA KATSUTOSHI , FUKANO AKIRA
IPC分类号： B41J2/415 , B41J2/385
CPC分类号： B41J2/4155
摘要： An image forming device which feeds toner (2) supplied from a toner carrier (1) to an image receiver (7) via a toner passage hole (4) by applying image-signal-dependent image signal voltages to control electrodes (10), wherein each image signal voltage consists of a plurality of pulse voltages corresponding to an image signal gradation, and an image signal voltage applying time is varied by changing the number of pulse voltages according to an image signal so corrected as to change an image signal gradation and by changing the pulse width of a pulse voltage. An image signal processor (16) provides different voltage potentials or voltage applying times to different control electrodes (10) in downstream-side rows in accordance with image signals corresponding to control electrodes (10) which are in upstream-side rows and adjacent to control electrodes (10) in downstream-side rows in a direction parallel to rows.
摘要翻译：一种图像形成装置，其通过将图像信号相关的图像信号电压施加到控制电极（10），通过调色剂通孔（4）将从调色剂载体（1）供应的调色剂（2）馈送到图像接收器（7）其中每个图像信号电压由对应于图像信号灰度的多个脉冲电压组成，并且图像信号电压施加时间根据改变图像信号等级的图像信号而改变脉冲电压的数量而变化，并且通过改变脉冲电压的脉冲宽度。图像信号处理器（16）根据与控制电极（10）相对应的图像信号向下游侧行中的不同控制电极（10）提供不同的电压电压或电压施加时间，所述控制电极（10）处于上游侧行并且与控制在与行平行的方向上的下游侧行中的电极（10）。

5. 发明专利

JPH09322271A DEVICE INFORMING LOCATION OF REMOTE CONTROLLER 失效
公开(公告)号：JPH09322271A
公开(公告)日：1997-12-12
申请号：JP17408496
申请日：1996-05-30
申请人： ITO TAICHI , HIROKAWA YASUAKI
发明人： ITO TAICHI , HIROKAWA YASUAKI
IPC分类号： H04Q9/00
摘要： PROBLEM TO BE SOLVED: To obtain the device that informs where it is by providing a transmitter to a body and sending a signal through the control so as to allow a receiver built in the remote controller to reply the signal and to send a light or a sound. SOLUTION: A transmitter 2 is built in a body 1 and a remote controller 5 receiving an electric signal 3 sent from the transmitter 2 is provided with the receiver and the device sending a light or a sound or the like. When the user desires to operate the remote controller 5 and cannot find out at hand, the user controls the transmitter 2 of the body 1 to allow the remote controller 5 to send a light or a sound, then the remote controller 5 is found out immediately.

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