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1. 发明申请

WO2007070584A2 NEEDLE CONSTRUCTED WITH A TRANSPARENT OR TRANSLUCENT MATERIAL 审中-公开
标题翻译：用透明或透明材料构成的针
公开(公告)号：WO2007070584A2
公开(公告)日：2007-06-21
申请号：PCT/US2006047554
申请日：2006-12-14
申请人： ACCESS SCIENT , GELIEBTER DAVID , ANDERSON JANELLE R
发明人： GELIEBTER DAVID , ANDERSON JANELLE R
IPC分类号： A61M5/32
CPC分类号： A61M5/329 , A61M5/3291 , A61M2005/3201
摘要： In general, the invention features needles, with or without lumens, that contain a barrel being transparent or translucent or having a transparent or translucent portion. Needles of the invention may further include a lumen, the interior of which is visualizable through the transparent or translucent portion. A needle may also include a portion to which a suture is capable of being attached.
摘要翻译：通常，本发明的特征在于具有或不具有流明的针，其具有透明或半透明的或具有透明或半透明部分的筒体。本发明的针可以进一步包括内腔，其内部可通过透明或半透明部分显现。针还可以包括能够连接缝合线的部分。

2. 发明申请

WO2007124110A3 VASODIALATING DRESSING FOR USE WITH INTRAVENOUS CATHETERS 审中-公开
标题翻译： VASODIALATING DRESSING用于内窥镜
公开(公告)号：WO2007124110A3
公开(公告)日：2008-12-04
申请号：PCT/US2007009756
申请日：2007-04-19
申请人： CURE THERAPEUTICS INC , ANG ROBERT , GELIEBTER DAVID
发明人： ANG ROBERT , GELIEBTER DAVID
IPC分类号： A61F13/02 , A61F13/00 , A61M29/00
CPC分类号： A61L15/44 , A61K31/21 , A61L15/58 , A61L2300/204 , A61L2300/40 , A61L2300/602
摘要： The present invention is drawn to adhesive dressings and associated systems and methods for use in reducing the occurrence of phlebitis and extending the lifespan of intravenous catheters. The adhesive dressings can include a backing layer, and a nitroglycerin-containing composition supported at least in part by the backing layer. The adhesive dressing can have a drug delivery zone defined by the area where the nitroglycerin-containing composition contacts an intact human skin site. The drug delivery zone can have an area of at least 2.5 cm2 and can be configured such that when the adhesive dressing is applied to secure an intravenous catheter the drug delivery zone substantially overlays a vessel in which the intravenous catheter is inserted. The nitroglycerin-containing composition can be formulated to deliver nitroglycerin at from about 5 µg/hour to about 80 µg/hour.
摘要翻译：本发明涉及用于减少静脉炎发生并延长静脉内导管的寿命的粘合剂敷料和相关系统和方法。粘合剂敷料可以包括背衬层和至少部分由背衬层支撑的含有硝酸甘油的组合物。粘合敷料可以具有由含硝酸甘油的组合物接触完整的人皮肤部位的区域限定的药物递送区域。药物递送区可以具有至少2.5cm 2的面积，并且可以构造成使得当施加粘合剂敷料以固定静脉内导管时，药物递送区基本上覆盖其中插入静脉内导管的血管。含硝酸甘油的组合物可配制成以约5μg/小时至约80μg/小时递送硝酸甘油。

3. 发明申请

WO2007143637A2 ORIENTATION IDENTIFICATION 审中-公开
标题翻译：方位识别
公开(公告)号：WO2007143637A2
公开(公告)日：2007-12-13
申请号：PCT/US2007070381
申请日：2007-06-05
申请人： GELIEBTER DAVID
发明人： GELIEBTER DAVID
IPC分类号： A61K49/04 , G01T1/10
CPC分类号： A61K49/0409 , A61K49/0447
摘要： A pair of anatomic orientation stickers may include a left-hand sticker comprising a radiopaque material forming a figure "L" and an adhesive backing attached thereto, and a right-hand sticker comprising a radiopaque material forming a figure "R" and an adhesive backing attached thereto. The stickers may be sufficiently flexible and biocompatible, and the adhesive backings are sufficiently adhesive, to permit removable application on a curved skin surface.
摘要翻译：一对解剖取向贴纸可以包括左手贴纸，其包括形成图形“L”的不透射线材料和附着在其上的粘合剂背衬，以及右手贴纸，其包含形成图“R”的不透射线材料和粘合剂背衬附在其上。贴纸可以具有足够的柔性和生物相容性，并且粘合剂背衬是足够粘合的，以允许在弯曲的皮肤表面上的可移除的应用。

4. 发明申请

WO2007100910A2 TRANSDERMAL PATCHES CONTAINING A NITRIC OXIDE-DONOR AND A SECOND ACTIVE AGENT AND ASSOCIATED METHODS 审中-公开
标题翻译：含有氮氧化物和第二活性剂及其相关方法的透皮胶条
公开(公告)号：WO2007100910A2
公开(公告)日：2007-09-07
申请号：PCT/US2007005395
申请日：2007-02-28
申请人： CURE THERAPEUTICS INC , ANG ROBERT , JACOBSON SVEN , WEIMMAN LUDWIG , MURRELL GEORGE ANTHONY CALVERT , GELIEBTER DAVID
发明人： ANG ROBERT , JACOBSON SVEN , WEIMMAN LUDWIG , MURRELL GEORGE ANTHONY CALVERT , GELIEBTER DAVID
IPC分类号： A61K31/21
CPC分类号： A61K9/7061 , A61K33/00 , A61K45/06
摘要： The present invention is drawn to a transdermal patch for the delivery of a nitric oxide-donor and a second active agent. The patch can comprise a backing layer and an active agent-containing composition which is supported at least in part by the backing layer. The active agent-containing composition can include an amount of a nitric oxide-donor and an amount of a second active agent. The transdermal patch can have a drug delivery zone defined by the area where the composition contacts an intact human skin site, and the transdermal patch can be formulated to deliver a nitric oxide donor, such as nitroglycerin, at from about 5 µg/hour to about 85 µg/hour. The second active agent can be selected from a number of agents including NSAIDS, opioids, local anesthetics, menthol, salicylic acid, salicylic acid derivatives, vanilloid receptor- 1 activators, corticosteroids, vasoconstrictors, and combinations thereof.
摘要翻译：本发明涉及用于递送一氧化氮给体和第二活性剂的透皮贴片。贴剂可以包括背衬层和至少部分由背衬层支撑的含活性剂的组合物。含活性剂的组合物可以包括一定量的一氧化氮供体和一定量的第二活性剂。透皮贴剂可以具有由组合物接触完整的人皮肤部位的区域限定的药物递送区，并且透皮贴剂可以配制成以约5μg/小时至约约1μg/小时递送一氧化氮供体，例如硝酸甘油 85微克/小时。第二活性剂可以选自许多试剂，包括NSAIDS，阿片样物质，局部麻醉剂，薄荷醇，水杨酸，水杨酸衍生物，香草素受体-1激活剂，皮质类固醇，血管收缩剂及其组合。

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