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1. 发明申请

WO2004069310A2 AN INTEGRATED MODULE FOR EXTRACORPOREAL BLOOD TREATMENT. 审中-公开
标题翻译：用于提取血液治疗的综合模块。
公开(公告)号：WO2004069310A2
公开(公告)日：2004-08-19
申请号：PCT/IB2004/000069
申请日：2004-01-14
申请人： GAMBRO LUNDIA AB , DUCHAMP, Jacques , ABERKANE, Aziz , POUCHOULIN, Dominique , MEYSSONNIER, Gabriel , RIBOLZI, Francesco , NERI, Roberto
发明人： DUCHAMP, Jacques , ABERKANE, Aziz , POUCHOULIN, Dominique , MEYSSONNIER, Gabriel , RIBOLZI, Francesco , NERI, Roberto
IPC分类号： A61M1/16
CPC分类号： A61M1/3621 , A61M2205/126 , A61M2205/128
摘要： An integrated module for extracorporeal blood treatment comprises a flat-shaped support element which exhibits on an internal face thereof a complex of fluid distribution lines and on an external face thereof a high-flow dialyzer. The support element comprises a base body (1) which exhibits fixture seatings (2), each of which houses an axially extended tract (38) of a fluid distribution line. The tract of line, with respect to adjacent tracts, has an increased diameter which is caused by a junction collar (39). Each fixture seating exhibits two axial locators (3a, 3b) for positioning the axial tract of line in a fixed position. The distribution lines are fixed to the base body by a resilient fixture of the junction collars in the seatings, with no necessity of gluing. The module is destined to be mounted on an apparatus for intensive treatment of renal insufficiency.
摘要翻译：用于体外血液处理的集成模块包括平面状支撑元件，其在其内表面上显示流体分配线的复合体，并且在其外表面上展示高流量透析器。支撑元件包括基体（1），其具有固定座（2），每个座体容纳流体分配线的轴向延伸的管道（38）。线路相对于相邻的道具有由接合环（39）引起的增加的直径。每个固定座具有两个轴向定位器（3a，3b），用于将轴向管线定位在固定位置。分配线通过座椅中的连接套环的弹性固定件固定到基体上，而不需要胶合。该模块注定要安装在肾功能不全的强化治疗装置上。

2. 发明申请

WO2004069311A1 EXTRACORPOREAL BLOOD TREATMENT MACHINE. 审中-公开
标题翻译：超声波血液治疗机。
公开(公告)号：WO2004069311A1
公开(公告)日：2004-08-19
申请号：PCT/IB2004/000062
申请日：2004-01-14
申请人： GAMBRO LUNDIA AB , CHEVALLET, Jacques , DUCHAMP, Jacques , ABERKANE, Aziz , MEYSSONNIER, Gabriel , POUCHOULIN, Dominique , RIBOLZI, Francesco , DELNEVO, Annalisa , TONELLI, Claudio , ZACCARELLI, Massimo , BARALDI, Vincenzo
发明人： CHEVALLET, Jacques , DUCHAMP, Jacques , ABERKANE, Aziz , MEYSSONNIER, Gabriel , POUCHOULIN, Dominique , RIBOLZI, Francesco , DELNEVO, Annalisa , TONELLI, Claudio , ZACCARELLI, Massimo , BARALDI, Vincenzo
IPC分类号： A61M1/34
CPC分类号： A61M1/342 , A61M1/16 , A61M1/1605 , A61M1/3434 , A61M1/3437 , A61M1/3451 , A61M2205/12 , A61M2205/128 , A61M2205/3393 , A61M2230/30
摘要： The invention relates to an extracorporeal blood treatment machine in which a blood circuit (3) is equipped with an inlet line leading to a filtration unit (2) and with an outlet line (3b) from the filtration unit; a fluid circuit comprises an inlet line (4a) leading to the filtration unit and an outlet line (4b) from the filtration unit so as to allow a fluid taken from a primary container (5) to circulate within the filtration unit. There is further an infusion line (6) acting on the outlet line of the blood circuit, which is supplied by an auxiliary fluid container (7). The inlet line of the fluid circuit is equipped with an infusion branch (8) acting on the outlet line of the blood circuit so as to enable the intensive therapy machine to manage therapies with large exchange of fluids.
摘要翻译：本发明涉及一种体外血液处理机，其中血液回路（3）配备有通向过滤单元（2）的入口管线和来自过滤单元的出口管线（3b）; 流体回路包括通向过滤单元的入口管线（4a）和来自过滤单元的出口管线（4b），以允许从主要容器（5）中取出的流体在过滤单元内循环。还有一个输入管线（6）作用在血液回路的出口管线上，该输液管线由辅助流体容器（7）供应。流体回路的入口管线配备有作用在血液回路出口管线上的输注支路（8），以使得强化治疗机器能够以大量的流体交换来管理治疗。

3. 发明申请

WO2004069299A2 SUPPORT ELEMENT FOR AN INTEGRATED BLOOD TREATMENT MODULE 审中-公开
标题翻译：一体化血液治疗模块的支持单元
公开(公告)号：WO2004069299A2
公开(公告)日：2004-08-19
申请号：PCT/IB2004/000105
申请日：2004-01-19
申请人： GAMBRO LUNDIA AB , CHEVALLET, Jacques , DUCHAMP, Jacques , ABERKANE, Aziz , MEYSSONNIER, Gabriel , DELNEVO, Annalisa , TONELLI, Claudio , ZACCARELLI, Massimo , RIBOLZI, Francesco , BARALDI, Vincenzo , POUCHOULIN, Dominique
发明人： CHEVALLET, Jacques , DUCHAMP, Jacques , ABERKANE, Aziz , MEYSSONNIER, Gabriel , DELNEVO, Annalisa , TONELLI, Claudio , ZACCARELLI, Massimo , RIBOLZI, Francesco , BARALDI, Vincenzo , POUCHOULIN, Dominique
IPC分类号： A61M
CPC分类号： A61M1/16 , A61M1/1605 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3451 , A61M1/3465 , A61M2205/126 , A61M2205/3334 , A61M2205/3393 , A61M2205/50
摘要： The invention relates to support element (4) comprising a main body (6) having a front wall (25) and a peripheral wall (32) projecting away from the front wall (25). The front wall (25) and the peripheral wall (32) define a housing compartment (33) designed to receive a fluid distribution circuitry cooperating with a treatment unit for defining an integrated blood treatment module.
摘要翻译：本发明涉及包括主体（6）的支撑元件（4），其具有前壁（25）和远离前壁（25）突出的周壁（32）。前壁（25）和周壁（32）限定了外壳隔室（33），其设计成接收与治疗单元配合的流体分配电路，用于限定集成的血液处理模块。

4. 发明申请

WO2004069308A1 INTEGRATED BLOOD TREATMENT MODULE AND EXTRACORPOREAL BLOOD TREATMENT APPARATUS. 审中-公开
标题翻译：一体化血液治疗模块和提取血液治疗装置。
公开(公告)号：WO2004069308A1
公开(公告)日：2004-08-19
申请号：PCT/IB2004/000104
申请日：2004-01-19
申请人： GAMBRO LUNDIA AB , CHEVALLET, Jacques , DUCHAMP, Jacques , ABERKANE, Aziz , MEYSSONNIER, Gabriel , DELNEVO, Annalisa , TONELLI, Claudio , ZACCARELLI, Massimo , RIBOLZI, Francesco , BARALDI, Vincenzo , POUCHOULIN, Dominique
发明人： CHEVALLET, Jacques , DUCHAMP, Jacques , ABERKANE, Aziz , MEYSSONNIER, Gabriel , DELNEVO, Annalisa , TONELLI, Claudio , ZACCARELLI, Massimo , RIBOLZI, Francesco , BARALDI, Vincenzo , POUCHOULIN, Dominique
IPC分类号： A61M1/16
CPC分类号： A61M1/3621 , A61M2205/126 , A61M2205/128
摘要： The invention relates to an integrated blood treatment module (1) comprising a support element and a fluid distribution circuitry associated thereto (15); the distribution circuitry (15) comprises at least a blood line (44), a portion of which is secured to the support element and defines with the latter at least a U-shaped tube length (44a) designed to cooperate, when in use, with a respective pump. There are then further fluid lines (45, 48, 50, 51) fastened to the support element and defining each at least a U-shaped tube length (45a, 48a, 50a, 51a) with respect to said element and each designed to cooperate, when in use, with a respective pump. The support element has a first zone (274) in which the portion of the blood line (44) is secured, and at least a second zone (275) opposite said first zone, to which all the corresponding further tube lengths are fastened.
摘要翻译：本发明涉及一种集成血液处理模块（1），其包括支撑元件和与其相关联的流体分配电路（15）; 分配电路（15）包括至少一条血液线（44），其一部分固定到支撑元件上，并且与血管线（44）形成至少一个U形管长度（44a），其设计成在使用时协作，与相应的泵。然后有另外的流体管线（45,48,50,51）固定到支撑元件并且相对于所述元件限定每个至少一个U形管长度（45a，48a，50a，51a），并且每个设计成配合在使用时，使用相应的泵。支撑元件具有固定血液管线部分（44）的第一区域（274）和与所述第一区域相对的至少第二区域（275），所有相应的另外的管道长度被紧固到该第二区域。

5. 发明申请

WO2004069309A1 A SUPPORT ELEMENT FOR AN INTEGRATED MODULE FOR BLOOD TREATMENT 审中-公开
标题翻译：用于血液处理的集成模块的支持单元
公开(公告)号：WO2004069309A1
公开(公告)日：2004-08-19
申请号：PCT/IB2004/000055
申请日：2004-01-13
申请人： GAMBRO LUNDIA AB , DUCHAMP, Jacques , ABERKANE, Aziz , POUCHOULIN, Dominique , MEYSSONNIER, Gabriel
发明人： DUCHAMP, Jacques , ABERKANE, Aziz , POUCHOULIN, Dominique , MEYSSONNIER, Gabriel
IPC分类号： A61M1/16
CPC分类号： A61M1/3621 , A61M2205/126 , A61M2205/128
摘要： The support element (4) is provided with a plurality of connectors (7), (8), (11) which receive corresponding counter-connectors of a blood treatment device. The support element is also predisposed to include a fluid distribution circuitry cooperating with the blood treatment device in order to provide an integrated module for blood treatment. An assembly process of the integrated module for blood treatment is also described.
摘要翻译：支撑元件（4）设置有多个连接器（7），（8），（11），其接收血液处理装置的相应的对连接器。支撑元件还易于包括与血液处理装置配合的流体分配电路，以提供用于血液处理的集成模块。还描述了用于血液处理的集成模块的组装过程。

6. 发明申请

WO2010029401A3 A PROCEDURE AND A DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT USING CITRATE ANTICOAGULATION 审中-公开
公开(公告)号：WO2010029401A3
公开(公告)日：2010-03-18
申请号：PCT/IB2009/006763
申请日：2009-09-04
申请人： GAMBRO LUNDIA AB , POUCHOULIN, Dominique , CHEVALLET, Jacques
发明人： POUCHOULIN, Dominique , CHEVALLET, Jacques
IPC分类号： A61M1/14 , A61M1/34 , A61M1/36
摘要： A device for blood treatment by extracorporeal circulation including a filter having a first and a second chambers with a semi-permeable membrane, an arterial line connected to the first chamber and associated to a first pump Qb, a venous line out from the first chamber, a first pre-infusion line (109) connected to a citrate container and associated to a second pump Qpre1, a first post-infusion line connected to a calcium solution container associated to a third pump Qpost1, an effluent line at the outlet of the second chamber connected to a drain and associated to a fourth pump Qeff, a CPU including first means programmed to receive the signals output by at least one of the pumps and second means programmed to control third post-infusion pump Qpost1 (121) as a function of the flow rate Qb, Qeff, and Qpre1.

7. 发明申请

WO2013030643A1 MEDICAL APPARATUS FOR EXTRACORPOREAL TREATMENT OF FLUID AND A PROCESS OF CALCULATING SET FLOW RATES IN A MEDICAL APPARATUS FOR DELIVERY OR COLLECTION OF FLUIDS 审中-公开
标题翻译：用于流体处理的医疗装置和计算用于输送或收集流体的医疗装置中的流量的方法
公开(公告)号：WO2013030643A1
公开(公告)日：2013-03-07
申请号：PCT/IB2012/001621
申请日：2012-08-22
申请人： GAMBRO LUNDIA AB , RADA, Hiram , POUCHOULIN, Dominique , VANTARD, Georges , FRUGIER, Alain
发明人： RADA, Hiram , POUCHOULIN, Dominique , VANTARD, Georges , FRUGIER, Alain
IPC分类号： A61M1/16 , A61M1/34
CPC分类号： A61M1/1613 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1611 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3609 , A61M2202/0413 , A61M2205/3331 , A61M2205/3334 , A61M2205/502 , A61M2205/52 , A61M2205/75 , G01F1/00
摘要： An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit (10) is configured calculate set values of two or more of the fluid flow rates by imposing that an emptying time of containers of fresh fluid (16, 20, 21, 26) and/or a filling time of a waste container is substantially same as, or multiple of, the emptying time of one or more of the other containers of fresh fluid.
摘要翻译：公开了用于流体体外处理的装置和设置用于输送或收集流体的医疗装置的过程。根据该装置和过程，控制单元（10）被配置为通过将新鲜流体（16,20,21,26）的容器的排空时间和/ 或废物容器的填充时间与新鲜流体的一个或多个其他容器的排空时间基本相同或多倍。

8. 发明申请

WO2013030642A1 APPARATUS FOR EXTRACORPOREAL TREATMENT OF BLOOD AND PROCESS OF CALCULATING SET FLOW RATES IN A MEDICAL APPARATUS FOR DELIVERY OR COLLECTION OF FLUIDS 审中-公开
标题翻译：用于血液处理的装置和计算用于输送或收集流体的医疗装置中的流量的流程
公开(公告)号：WO2013030642A1
公开(公告)日：2013-03-07
申请号：PCT/IB2012/001620
申请日：2012-08-23
申请人： GAMBRO LUNDIA AB , POUCHOULIN, Dominique
发明人： POUCHOULIN, Dominique
IPC分类号： A61M1/16 , A61M1/34
CPC分类号： A61M1/1613 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/341 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M1/3607 , A61M1/3609 , A61M2202/0413 , A61M2205/3331 , A61M2205/3334 , A61M2205/3393 , A61M2205/502 , A61M2205/52 , A61M2205/75 , G01F1/00 , G06F19/00 , G06F19/3468
摘要： An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit (10) is configured calculate set values of two or more of the fluid flow rates based on a fluid flow rate set by the operator and on a prescribed dose value (D set ).
摘要翻译：公开了用于流体体外处理的装置和设置用于输送或收集流体的医疗装置的过程。根据该装置和处理，控制单元（10）被配置为基于由操作者设定的流体流量和规定的剂量值（Dset）计算流体流量的两个以上的设定值。

9. 发明申请

WO2012042323A2 APPARATUS FOR EXTRACORPOREAL TREATMENT OF BLOOD 审中-公开
标题翻译：用于血液提取物治疗的装置
公开(公告)号：WO2012042323A2
公开(公告)日：2012-04-05
申请号：PCT/IB2011/002098
申请日：2011-09-08
申请人： GAMBRO LUNDIA AB , POUCHOULIN, Dominique
发明人： POUCHOULIN, Dominique
IPC分类号： A61M1/16
CPC分类号： A61M1/3663 , A61M1/16 , A61M1/1601 , A61M1/1643 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3451 , A61M2205/3334 , A61M2205/3393 , A61M2205/50 , A61M2205/505
摘要： An apparatus for extracorporeal treatment of blood (1) comprising a filtration unit (2), a blood withdrawal line (6), a blood return line (7), an effluent fluid line (13), a pre and/or post-dilution fluid line (15, 25) connected to the blood withdrawal line, and a dialysis fluid line. Pumps (17, 18, 21, 22, 27) act on the fluid lines for regulating the flow of fluid. A control unit (10) is configured to set initial values to one or more fluid flow rates through the above lines and to periodically execute a flow rate update procedure in order to deliver a set dose (Dset) in a reference time interval.
摘要翻译：一种用于血液体外处理的装置（1），包括过滤单元（2），抽血管线（6），血液回流管线（7），流出液体管线（13），前和/或后稀释连接到抽血管线的流体管线（15,25）和透析流体管线。泵（17,18,21,22,27）作用于用于调节流体流动的流体管线。控制单元（10）被配置为将初始值设置为通过上述线路的一个或多个流体流速，并且周期性地执行流量更新过程，以便在参考时间间隔内递送设定剂量（Dset）。

10. 发明申请

WO2010029417A2 DEVICE AND PROCEDURE FOR EXTRACORPOREAL BLOOD TREATMENT 审中-公开
标题翻译：超临界血液治疗的设备和程序
公开(公告)号：WO2010029417A2
公开(公告)日：2010-03-18
申请号：PCT/IB2009/006801
申请日：2009-09-09
申请人： GAMBRO LUNDIA AB , POUCHOULIN, Dominique , CHEVALLET, Jacques
发明人： POUCHOULIN, Dominique , CHEVALLET, Jacques
CPC分类号： A61M1/3672 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3458 , A61M1/3675
摘要： An extracorporeal blood treatment device including a filter having a primary and a secondary chamber separated by a semi¬ permeable membrane, a withdrawal line connected to the primary chamber and associated to a first pump, a return line at the outlet of the primary chamber, a first pre-infusion line (109) connected to a citrate container on the withdrawal line (106), associated to a second pump, a first post- infusion line connected to a calcium solution container and to the return line, and associated to a third pump, an effluent line from the secondary chamber connected to a drain pipe and associated to a fourth pump, a CPU including first means programmed to receive the signal output by the pumps and second means programmed to control the third post- infusion pump (121) as a function of the input flow rate, effluent liquid flow rate, and anticoagulation liquid flow rate.
摘要翻译：一种体外血液处理装置，其包括具有由半透膜隔开的初级和次级室的过滤器，连接到主室并与第一泵连接的抽出管线，在主室的出口处的返回管线，连接到抽出管线（106）上的柠檬酸盐容器的第一预输注管线（109），其与第二泵相关联，连接到钙溶液容器和返回管线的第一输注后输液管线，并与第三泵泵，来自连接到排水管并且与第四泵相关联的辅助室的流出物管线，包括被编程为接收由泵输出的信号的第一装置和被编程以控制第三输注后泵（121）的第二装置的CPU，作为输入流量，流出液体流速和抗凝液体流速的函数。

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