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1. 发明申请

WO2003089027A3 BLOOD COMPONENT PROCESSING SYSTEM, APPARATUS AND METHOD 审中-公开
公开(公告)号：WO2003089027A3
公开(公告)日：2003-10-30
申请号：PCT/US2003/011764
申请日：2003-04-16
申请人： GAMBRO, INC.
发明人： HOGBERG, Niclas , PIHLSTEDT, Peter , HOLMES, Brian, M. , VAN WAEG, Geert , HALLGREN, Emanuel , PERSSON, Lars , STRANDBERG, Lars , CORBIN, Frank, III
IPC分类号： A61M1/36
摘要： A system and method are used in connection with processing of blood components. The processing of blood components may involve centrifugal separation and/or filtering of the blood components. In some examples, at least some blood components are centrifugally separated in a chamber and then filtered via a filter (31) rotating along with a centrifuge rotor (1), wherein the filter is located closer than the chamber to an axis of rotation of the rotor. The filter may include a porous filtration medium configured to filter leukocytes, platelets, and/or red blood cells. Some examples include a pressure sensor sensing pressure of pumped blood components. The sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products. Other uses of the sensed pressure are also possible.

2. 发明申请

WO2003089027A2 BLOOD COMPONENT PROCESSING SYSTEM, APPARATUS AND METHOD 审中-公开
标题翻译：血液组分处理系统，装置和方法
公开(公告)号：WO2003089027A2
公开(公告)日：2003-10-30
申请号：PCT/US2003/011764
申请日：2003-04-16
申请人： GAMBRO, INC.
发明人： HOGBERG, Niclas , PIHLSTEDT, Peter , HOLMES, Brian, M. , VAN WAEG, Geert , HALLGREN, Emanuel , PERSSON, Lars , STRANDBERG, Lars , CORBIN, Frank, III
IPC分类号： A61M1/36
CPC分类号： B04B13/00 , A61M1/0209 , A61M1/0218 , A61M1/025 , A61M1/26 , A61M1/262 , A61M1/3633 , A61M1/3639 , A61M1/3641 , A61M1/3693 , A61M1/3696 , A61M1/3698 , A61M2205/331 , B04B5/0428 , B04B5/0442 , B04B2005/045 , B04B2005/0478 , B04B2013/006
摘要： A system and method are used in connection with processing of blood components. The processing of blood components may involve centrifugal separation and/or filtering of the blood components. In some examples, at least some blood components are centrifugally separated in a chamber and then filtered via a filter rotating along with a centrifuge rotor, wherein the filter is located closer than the chamber to an axis of rotation of the rotor. The filter may include a porous filtration medium configured to filter leukocytes, platelets, and/or red blood cells. Some examples include a pressure sensor sensing pressure of pumped blood components. The sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products. Other uses of the sensed pressure are also possible.
摘要翻译：与血液成分的处理有关的系统和方法。血液成分的处理可能涉及血液成分的离心分离和/或过滤。在一些实例中，至少一些血液成分在室中离心分离，然后通过与离心机转子一起旋转的过滤器过滤，其中过滤器位于离转子更靠近转动轴的位置。过滤器可以包括被配置为过滤白细胞，血小板和/或红细胞的多孔过滤介质。一些示例包括感测泵送的血液成分的压力的压力传感器。感测到的压力可以与控制血液制品的泵送和/或与确定与血液制品相关联的界面的位置的结合一起使用。感测压力的其他用途也是可能的。

3. 发明申请

WO2005082540A1 APPARATUS AND METHOD FOR SEPARATING A VOLUME OF COMPOSITE LIQUID INTO AT LEAST TWO COMPONENTS 审中-公开
标题翻译：将复合液体体积分解成至少两个组分的装置和方法
公开(公告)号：WO2005082540A1
公开(公告)日：2005-09-09
申请号：PCT/US2005/004252
申请日：2005-02-10
申请人： GAMBRO, INC. , HOLMES, Brian, M. , VAN WAEG, Geert , PIHLSTEDT, Peter
发明人： HOLMES, Brian, M. , VAN WAEG, Geert , PIHLSTEDT, Peter
IPC分类号： B04B1/00
CPC分类号： B04B13/00 , A61M1/0209 , A61M1/029 , B04B2013/006
摘要： A method for separating a volume of a composite liquid into at least a first component and a second component is performed in a centrifuge (35, 36, 37, 38) cooperating with a separation bag (1) containing the volume of composite liquid. The separation bag is connected to at least a first component bag (2) and a second component bag (3). The separation bag (1) is spun so as to centrifuge the volume of composite liquid and cause the sedimentation of the at least first and second components. When the at least first and second components have sedimented, the first component is transferred at at least one first transfer flow rate into the first component bag (2). When the first component has been transferred into the first component bag, the second component is transferred into the second component bag (3) at at least one second transfer flow rate that is different from the at least one first transfer flow rate.
摘要翻译：在与包含复合液体体积的分离袋（1）配合的离心机（35,36,37,38）中进行将复合液体的体积分离为至少第一成分和第二成分的方法。分离袋连接到至少第一组分袋（2）和第二组分袋（3）。旋转分离袋（1）以离心复合液体的体积并引起至少第一和第二组分的沉淀。当至少第一和第二组分沉淀时，第一组分以至少一个第一转移流速转移到第一组分袋（2）中。当第一组分被转移到第一组分袋中时，第二组分以不同于至少一个第一转移流速的至少一个第二转移流速转移到第二组分袋（3）中。

4. 发明授权

EP1223954B1 METHOD AND APPARATUS FOR PROCESSING BLOOD AND BLOOD COMPONENTS 有权
标题翻译：方法在设备上使用ZUR BEHANDLUNG VON BLUT BLUBKONENTEN
公开(公告)号：EP1223954B1
公开(公告)日：2005-03-09
申请号：EP00935797.1
申请日：2000-05-26
申请人： Gambro Inc.
发明人： HÖGBERG, Niclas , HÄLLGREN, Emanuel , PIHLSTEDT, Peter
IPC分类号： A61K35/14 , B01F11/00
CPC分类号： B01F11/0017 , A61M1/0209 , A61M1/3692 , A61M1/3693 , A61M1/3696 , B01F3/0803 , B01F2003/0896 , B01F2215/0034
摘要： The claimed invention relates to a method and a device for processing blood concentrate products before they are exposed to a continued process for extracting those remaining medicinally interesting sub-components. The appropriate pre-processing, in relation to the invention, primarily entails a mechanically powered resolution of the viscous flowing concentrate products in a diluting solution for the adaptation of the total products for a renewed centrifuging.
摘要翻译：所要求保护的发明涉及一种用于处理血液浓缩物产品的方法和装置，该方法和装置在暴露于用于提取剩余的药物感兴趣的子组件的持续过程之前。与本发明相关的适当的预处理主要涉及在稀释溶液中机械动力地分离粘性流动的浓缩物产品，以便适应用于再次离心的总产品。

5. 发明公开

EP1494735A2 BLOOD COMPONENT PROCESSING SYSTEM, APPARATUS AND METHOD 有权
标题翻译：系统和方法处理血液成分
公开(公告)号：EP1494735A2
公开(公告)日：2005-01-12
申请号：EP03719786.0
申请日：2003-04-16
申请人： Gambro, Inc.
发明人： HOGBERG, Niclas , PIHLSTEDT, Peter , HOLMES, Brian, M. , VAN WAEG, Geert , HALLGREN, Emanuel , PERSSON, Lars , STRANDBERG, Lars , CORBIN, Frank, III
IPC分类号： A61M1/36
CPC分类号： B04B13/00 , A61M1/0209 , A61M1/0218 , A61M1/025 , A61M1/26 , A61M1/262 , A61M1/3633 , A61M1/3639 , A61M1/3641 , A61M1/3693 , A61M1/3696 , A61M1/3698 , A61M2205/331 , B04B5/0428 , B04B5/0442 , B04B2005/045 , B04B2005/0478 , B04B2013/006
摘要： A system and method are used in connection with processing of blood components. The processing of blood components may involve centrifugal separation and/or filtering of the blood components. In some examples, at least some blood components are centrifugally separated in a chamber and then filtered via a filter (31) rotating along with a centrifuge rotor (1), wherein the filter is located closer than the chamber to an axis of rotation of the rotor. The filter may include a porous filtration medium configured to filter leukocytes, platelets, and/or red blood cells. Some examples include a pressure sensor sensing pressure of pumped blood components. The sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products. Other uses of the sensed pressure are also possible.

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