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    • 5. 发明授权
    • Dispenser for an adhesive tissue sealant having a housing with multiple cavities
    • 用于具有多个腔体的粘合剂组织密封剂的分配器
    • US06458095B1
    • 2002-10-01
    • US09524141
    • 2000-03-10
    • David F. WirtLarry H. DodgeJeffrey D. Smith
    • David F. WirtLarry H. DodgeJeffrey D. Smith
    • A61M3700
    • A61B17/00491A61B50/30A61B2017/00495A61M5/19A61M5/3129A61M11/06
    • A dispenser in which a dry powder (one component of a two-part adhesive tissue sealant and/or adhesive) is stored in a container (e.g., a carpule) having a septum at one end, an open end opposite the septum, and a movable plug. The powder is retained at the septum end of the container by the movable plug, which is displaced and pushed back as the solvent used for reconstituting the powder is introduced (e.g., through the septum). The second part of the tissue sealant is contained within a second container, also with a movable plug. After the first part is reconstituted, a manifold is fitted which pierces both septums and allows the contents to be dispensed. A dual syringe body supports the containers, and has pistons that enter the open ends to advance the movable plugs. Other embodiments of tissue adhesive and/or sealant dispensers and kits as well as methods of preparing tissue sealants are also described.
    • 一种分配器,其中将干燥粉末(两部分粘合剂组织密封剂和/或粘合剂的一种组分)储存在一端具有隔膜的容器(例如,小胡椒)中,与隔膜相对的开口端,以及 活动插头 粉末通过可移动塞子保持在容器的隔膜端部,可移动塞子被引入(例如通过隔膜)用于重构粉末的溶剂时被移位并推回。 纸巾密封剂的第二部分包含在第二容器内,还带有可动塞。 在第一部分重新组装之后,安装一个歧管以刺穿两个隔膜并允许内容物被分配。 双注射器主体支撑容器,并且具有进入开口端的活塞以推动可动塞。 还描述了组织粘合剂和/或密封剂分配器和试剂盒的其它实施方案以及制备组织密封剂的方法。
    • 8. 发明授权
    • Biological sterilization indicator and method of using same
    • 生物灭菌指标及其使用方法
    • US08840837B2
    • 2014-09-23
    • US13881154
    • 2011-10-28
    • Jeffrey D. SmithJeffrey C. PedersonSailaja ChandrapatiRuthAnn R. Duda
    • Jeffrey D. SmithJeffrey C. PedersonSailaja ChandrapatiRuthAnn R. Duda
    • C12Q1/22C12Q1/02
    • C12Q1/22
    • A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.
    • 生物灭菌指示剂(BI)及其使用方法。 BI可以包括壳体和位于壳体中的容器。 容器可以容纳液体,容器的至少一部分可以是易碎的。 BI还可以包括第一室和第二室。 第二室可以包括至少一种生物活性来源。 BI还可以包括定位成流体耦合第一室和第二室的第一流体路径,以及定位成允许排出的气体移出第二室的第二流体路径。 该方法可以包括当消毒剂经由第一流体路径移动到第二室中时和/或当液体经由第一流体路径移动到第二室中时,通过第二流体路径将移动的气体移出第二室。