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1. 再颁专利

USRE43481E1 Diazepan derivatives or salts thereof 失效
标题翻译：二氮杂环庚烷衍生物或其盐
公开(公告)号：USRE43481E1
公开(公告)日：2012-06-19
申请号：US12203640
申请日：2008-09-03
申请人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
发明人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
IPC分类号： A61P7/02 , A61K31/55 , C07D223/04 , C07D401/00
CPC分类号： C07D401/04 , A61K31/551 , C07D243/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D471/04
摘要： To provide a compound which has an anticoagulation action based upon inhibition of activated blood coagulation factor X and is useful as an anticoagulant or an agent for prevention and treatment of diseases caused by thrombus or embolus. A diazepan derivative such as 4-[(3-carbamimidoylphenylamino)methyl]-3-[4-(4-methyl-1,4-diazepan-1-yl)benzoylamino]benzoic acid and 3-hydroxy-4′-methoxy-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzanilide or a salt thereof is an effective ingredient.
摘要翻译：提供具有基于活化凝血因子X的抑制的抗凝作用的化合物，并且可用作抗凝血剂或用于预防和治疗由血栓或栓塞引起的疾病的药剂。二氮杂环丁烷衍生物如4 - [（3-氨甲酰氨基）甲基] -3- [4-（4-甲基-1,4-二氮杂环庚烷-1-基）苯甲酰基氨基]苯甲酸和3-羟基-4'-甲氧基 - 2 - {[4-（4-甲基-1,4-二氮杂环庚烷-1-基）苯甲酰基]氨基} -N-苯甲酰苯胺或其盐是有效成分。

2. 发明授权

US07307074B2 Diazepan derivatives or salts thereof 有权
标题翻译：二氮杂环庚烷衍生物或其盐
公开(公告)号：US07307074B2
公开(公告)日：2007-12-11
申请号：US10656129
申请日：2003-09-08
申请人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
发明人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
IPC分类号： A61P7/02 , A61K31/55 , C07D223/04 , C07D401/00
CPC分类号： C07D401/04 , A61K31/551 , C07D243/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D471/04
摘要： To provide a compound which has an anticoagulation action based upon inhibition of activated blood coagulation factor X and is useful as an anticoagulant or an agent for prevention and treatment of diseases caused by thrombus or embolus. A diazepan derivative such as 4-[(3-carbamimidoylphenylamino)methyl]-3-[4-(4-methyl-1,4-diazepan-1-yl)benzoylamino]benzoic acid and 3-hydroxy-4′-methoxy-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzanilide or a salt thereof is an effective ingredient.
摘要翻译：提供具有基于活化凝血因子X的抑制的抗凝作用的化合物，并且可用作抗凝血剂或用于预防和治疗由血栓或栓塞引起的疾病的药剂。二氮杂环丁烷衍生物如4 - [（3-氨甲酰氨基）甲基] -3- [4-（4-甲基-1,4-二氮杂环庚烷-1-基）苯甲酰基氨基]苯甲酸和3-羟基-4'-甲氧基 - 2 - {[4-（4-甲基-1,4-二氮杂环庚烷-1-基）苯甲酰基]氨基} -N-苯甲酰苯胺或其盐是有效成分。

3. 发明授权

US06642224B1 Diazepan derivatives or salts thereof 失效
标题翻译：二氮杂环庚烷衍生物或其盐
公开(公告)号：US06642224B1
公开(公告)日：2003-11-04
申请号：US10148544
申请日：2002-10-02
申请人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
发明人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
IPC分类号： A61K3155
CPC分类号： C07D401/04 , A61K31/551 , C07D243/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D471/04
摘要： To provide a compound which has an anticoagulation action based upon inhibition of activated blood coagulation factor X and is useful as an anticoagulant or an agent for prevention and treatment of diseases caused by thrombus or embolus. A diazepan derivative such as 4-[(3-carbamimidoylphenylamino)methyl]-3-[4-(4-METHYL-1,4-diazepan-1-yl)benzoylamino]benzoic acid and 3-hydroxy-4′-methoxy-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzanilide or a salt thereof is an effective ingredient.
摘要翻译：提供具有基于活化凝血因子X的抑制的抗凝作用的化合物，并且可用作抗凝血剂或用于预防和治疗由血栓或栓塞引起的疾病的药剂。二氮杂环丁烷衍生物如4 - [（3-甲脒亚氨基苯基氨基）甲基] -3- [4-（4-甲基-1,4-二氮杂环庚烷-1-基）苯甲酰基氨基]苯甲酸和3-羟基-4'-甲氧基 - 2 - {[4-（4-甲基-1,4-二氮杂环庚烷-1-基）苯甲酰基]氨基} -N-苯甲酰苯胺或其盐是有效成分。

4. 发明授权

US06333320B1 Hexahydro-1,4-diazepine derivatives or salts thereof 失效
标题翻译：六氢-1,4-二氮杂衍生物或其盐
公开(公告)号：US06333320B1
公开(公告)日：2001-12-25
申请号：US09463017
申请日：2000-01-19
申请人： Hiroyuki Koshio , Fukushi Hirayama , Tsukasa Ishihara , Masashi Funatsu , Tomihisa Kawasaki , Yuzo Matsumoto
发明人： Hiroyuki Koshio , Fukushi Hirayama , Tsukasa Ishihara , Masashi Funatsu , Tomihisa Kawasaki , Yuzo Matsumoto
IPC分类号： A61K3155
CPC分类号： C07D405/12 , C07D243/08
摘要： Hexahydro-1,4-diazepine derivatives represented by general formula (I); pharmaceutically acceptable salts thereof; and drugs containing the same as the active ingredient, such as activated blood coagulation factor X inhibitor, wherein A: phenylene, pyridylene, or the like; B: a 5- or 6-membered aryl or heteroaryl ring; X: —CO—, —CONH—, —CSNH—, —SO2—, —SO2NH—, or the like; Y: a bond or alkylene; R1: hydrogen, alkyl, —Y—(hetero) aryl, or the like; R2: hydrogen, alkoxy, —COOH, or the like; R3: amidino or a group capable of being converted into amidino; and R4, R5: each independently hydrogen or lower alkyl.
摘要翻译：由通式（I）表示的六氢-1,4-二氮杂衍生物; 其药学上可接受的盐; 以及与活性成分相同的药物，例如活化凝血因子X抑制剂，其中A：亚苯基，亚吡啶基等; B：5-或6-元芳基或杂芳基环; X：-CO - ， - CONH - ， - CSH - ， - SO 2 - ， - SO 2 NH-等; Y：一个键或亚烷基; R1：氢，烷基，-Y-（杂）芳基等; R2：氢，烷氧基，-COOH等; R3：脒基或能够转化为脒基的基团; 和R 4，R 5：各自独立地为氢或低级烷基。

5. 发明授权

US5869501A Amidinonaphthyl derivative or salt thereof 失效
标题翻译：脒基萘基衍生物或其盐
公开(公告)号：US5869501A
公开(公告)日：1999-02-09
申请号：US849391
申请日：1997-05-30
申请人： Fukushi Hirayama , Hiroyuki Koshio , Yuzo Matsumoto , Tomihisa Kawasaki , Seiji Kaku , Isao Yanagisawa
发明人： Fukushi Hirayama , Hiroyuki Koshio , Yuzo Matsumoto , Tomihisa Kawasaki , Seiji Kaku , Isao Yanagisawa
IPC分类号： C07D211/44 , A61K31/445 , A61P7/02 , C07D211/46 , C07D401/12 , C07D409/12
CPC分类号： C07D401/12 , C07D211/46 , C07D409/12
摘要： An amidinonaphthyl derivative represented by the following general formula (I) which has coagulation factor X inhibiting action and is useful as an anti-thrombus agent and the like, a salt thereof, an intermediate thereof and a pharmaceutical composition which comprises the amidinonaphthyl derivative. An amidinonaphthyl derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof. ##STR1## (symbols in the formula have the following meanings; R.sup.1 : a hydrogen atom or a group represented by the formula --A--W--R.sup.4,A: a group represented by the formula ##STR2## a group represented by the formula ##STR3## or a group represented by the formula --SO.sub.2 --, X: an oxygen atom or a sulfur atom, W: a single bond or a group represented by the formula --NR.sup.5 --, R.sup.4 : a hydroxyl group, a lower alkoxy group, etc., R.sup.5 : a hydrogen atom, a carbamoyl group, a lower alkoxycarbonyl group, etc., R.sup.2 : a lower alkyl group, R.sup.3 : a hydrogen atom, a halogen atom, a carboxyl group, B: a lower alkylene group or a carbonyl group, and n: 0 or 1).
摘要翻译： PCT No.PCT / JP95 / 02458 Sec。 371日期1997年5月30日 102（e）日期1997年5月30日PCT提交1995年12月1日PCT公布。公开号WO96 / 16940 日期1996年6月6日由以下通式（I）表示的脒基萘基衍生物，其具有凝血因子X抑制作用，可用作抗血栓剂等，其盐，其中间体和药物组合物，其包含脒基萘基衍生物。由以下通式（I）表示的脒基萘基衍生物或其药学上可接受的盐。（式中的符号具有以下含义：R 1：氢原子或式-AW-R4表示的基团，A：由式SO 2表示的基团，由式 X：氧原子或硫原子，W：单键或由式-NR5-表示的基团，R4表示羟基，低级烷氧基等，R5表示氢原子，氨基甲酰基，低级烷氧基羰基等，R2：低级烷基，R3：氢原子，卤素原子，羧基，B：低级亚烷基或羰基，n：0或1）。

6. 发明授权

US08272634B2 Sheet feeding device, and image forming device 失效
标题翻译：送纸装置和图像形成装置
公开(公告)号：US08272634B2
公开(公告)日：2012-09-25
申请号：US12891170
申请日：2010-09-27
申请人： Yasuo Fukatsu , Tsuyoshi Moriyama , Yuzo Matsumoto
发明人： Yasuo Fukatsu , Tsuyoshi Moriyama , Yuzo Matsumoto
IPC分类号： B65H3/14
CPC分类号： B65H3/128 , B65H1/14 , B65H3/48 , B65H2405/15 , B65H2511/20 , B65H2511/222 , B65H2511/40 , B65H2801/06 , B65H2220/02 , B65H2220/11 , B65H2220/03
摘要： There is provided a sheet feeding device in which a sheet is discriminated at preliminary loosening before feeding, and is set to be controlled according to the type of the sheet by a simple configuration without requiring a special configuration. In the sheet feeding device in which air is blown onto a sheet stack, and a sheet floating at the uppermost level by the blowing is absorbed and conveyed, a sheet type is discriminated, based on a moving amount of the tray, at preliminary loosening before sheet feeding after setting the sheet in a tray.
摘要翻译：提供了一种片材进给装置，其中在进给之前初步松动地识别片材，并且通过简单的构造将其设置为根据片材的类型进行控制，而不需要特殊的构造。在将空气吹到片材堆叠上的片材供给装置中，通过吹送而浮动在最上层的片材被吸收并输送，基于托盘的移动量，在预先松开之前判别片材类型将纸张放入纸盘后进行送纸。

7. 发明授权

US07813660B2 Image adjusting method and image forming apparatus 有权
标题翻译：图像调整方法及图像形成装置
公开(公告)号：US07813660B2
公开(公告)日：2010-10-12
申请号：US11859075
申请日：2007-09-21
申请人： Katsumi Takahashi , Yuichiro Maeda , Yushi Oka , Kenji Kuroki , Yuzo Matsumoto , Kazunori Togashi , Takuya Kawamura
发明人： Katsumi Takahashi , Yuichiro Maeda , Yushi Oka , Kenji Kuroki , Yuzo Matsumoto , Kazunori Togashi , Takuya Kawamura
IPC分类号： G03G15/00
CPC分类号： G03G15/5062 , G03G15/2039 , G03G15/6564 , G03G2215/00067 , G03G2215/00569 , G03G2215/00599
摘要： An image forming apparatus forms a toner image onto sheets at the first feeding interval on a photoconductor or intermediate transfer member and, if the temperature of a fixing unit falls outside a set temperature range, the sheet layout is changed to a feeding interval wider than the first feeding interval. Adjustment processing is performed based on the image forming condition so that the feeding interval is changed to a wider one in the feeding interval changing step during image formation and it is determined in the determination step to perform adjustment processing, toner patch images are formed in an area where no toner image is formed on the photoconductor or intermediate transfer member . The adjustment processing is performed based on reading toner patch images.
摘要翻译：图像形成装置在光电导体或中间转印构件上以第一馈送间隔在片材上形成调色剂图像，并且如果定影单元的温度落在设定温度范围之外，则将片材布局改变为比第一次喂食间隔。基于图像形成条件进行调整处理，使得在图像形成期间的馈送间隔改变步骤中将馈送间隔变更到更宽的位置，并且在确定步骤中确定执行调整处理，调色剂片图像形成在在感光体或中间转印部件上不形成调色剂图像的区域。基于读取调色剂补片图像进行调整处理。

8. 发明授权

US07538315B2 Image forming apparatus and control method therefor 失效
标题翻译：图像形成装置及其控制方法
公开(公告)号：US07538315B2
公开(公告)日：2009-05-26
申请号：US11466094
申请日：2006-08-21
申请人： Yuzo Matsumoto
发明人： Yuzo Matsumoto
IPC分类号： G06F7/00 , H01J5/16
CPC分类号： H04N1/32459 , H04N1/0473 , H04N1/1135 , H04N1/32358 , H04N2201/0468 , H04N2201/0471 , H04N2201/04729 , H04N2201/04731 , H04N2201/04734 , H04N2201/04744 , H04N2201/04786 , H04N2201/04787 , H04N2201/04789 , H04N2201/04791 , H04N2201/04796
摘要： This invention makes it possible to prevent any uneven density and degradation in resolution in reciprocal laser scanning using a movable mirror. An image forming apparatus forms an image on a photosensitive member by scanning the photosensitive member with a laser beam reflected by a movable mirror with reciprocating the movable mirror whose rotation angle is changeable in accordance with an electrical signal. The apparatus detects the rotation direction of the movable mirror, and weights, on the basis of the rotation direction, image data of two lines along the sub-scanning direction in correspondence with the ratio of the scanning length after the start of laser write for a line of laser scanning to compensate the image to be formed using the movable mirror.
摘要翻译：本发明可以防止使用可移动反射镜的相互激光扫描中的不均匀浓度和分辨率的劣化。图像形成装置通过用可移动反射镜反射的激光束扫描感光部件，使感光部件的旋转角度根据电信号变化而使可动镜反复往复而形成感光部件上的图像。该装置检测可移动反射镜的旋转方向，并且基于旋转方向，对应于激光写入开始后的扫描长度的比例，沿着副扫描方向对两条线的图像数据进行加权激光扫描线来补偿使用可移动镜形成的图像。

9. 发明申请

US20080075486A1 IMAGE ADJUSTING METHOD AND IMAGE FORMING APPARATUS 有权
标题翻译：图像调整方法和图像形成装置
公开(公告)号：US20080075486A1
公开(公告)日：2008-03-27
申请号：US11859075
申请日：2007-09-21
申请人： Katsumi Takahashi , Yuichiro Maeda , Yushi Oka , Kenji Kuroki , Yuzo Matsumoto , Kazunori Togashi , Takuya Kawamura
发明人： Katsumi Takahashi , Yuichiro Maeda , Yushi Oka , Kenji Kuroki , Yuzo Matsumoto , Kazunori Togashi , Takuya Kawamura
IPC分类号： G03G15/00
CPC分类号： G03G15/5062 , G03G15/2039 , G03G15/6564 , G03G2215/00067 , G03G2215/00569 , G03G2215/00599
摘要： In an image forming apparatus which forms an image by transferring, onto sheets fed by a feeding unit at the first feeding interval, a toner image formed on a photoconductor or intermediate transfer member, if the temperature of a fixing unit which fixes an image transferred onto a sheet falls outside a set temperature range, the sheet layout is changed to a feeding interval wider than the first feeding interval. Whether to perform adjustment processing is determined based on determination of an image forming condition. If the feeding interval is changed to a wider one in the feeding interval changing step during image formation and it is determined in the determination step to perform adjustment processing, toner patch images are formed in an area where no toner image is formed on the photoconductor or intermediate transfer member. The adjustment processing is performed based on reading toner patch images.
摘要翻译：在形成图像的图像形成装置中，如果将转印到图像上的图像固定的定影单元的温度，将形成在感光体或中间转印部件上的调色剂图像转印到由馈送单元馈送的片材上，片材落在设定温度范围之外，片材布局改变为比第一馈送间隔宽的馈送间隔。基于图像形成条件的确定确定是否进行调整处理。如果在图像形成期间在馈送间隔改变步骤中将馈送间隔改变为更宽的位置，并且在确定步骤中确定执行调节处理，则在不在感光体上形成调色剂图像的区域中形成调色剂图像，中间转印部件。基于读取调色剂补片图像进行调整处理。

10. 发明授权

US07344130B2 Sheet processing apparatus and image processing apparatus 失效
标题翻译：片材处理装置和图像处理装置
公开(公告)号：US07344130B2
公开(公告)日：2008-03-18
申请号：US11551834
申请日：2006-10-23
申请人： Daisaku Kamiya , Masaharu Nemura , Junichi Moteki , Yuzo Matsumoto , Shunsuke Nishimura
发明人： Daisaku Kamiya , Masaharu Nemura , Junichi Moteki , Yuzo Matsumoto , Shunsuke Nishimura
IPC分类号： B65H37/04
CPC分类号： B65H45/18 , B65H2404/6111
摘要： The present invention relates to a sheet processor apparatus comprising: a sheet stack portion on which a sheet is stacked; a sheet conveyance path for conveying a sheet stacked on the sheet stack portion; a sheet conveyor for conveying to the sheet conveyance path the sheet stacked on the sheet stack portion; and a sheet folding device for folding a sheet in the sheet-set conveyance path. The sheet folding device is provided in the sheet conveyance path, and at least a portion of the sheet conveyance path at which the sheet folding device is positioned is formed into a curved shape.
摘要翻译：片材处理装置技术领域本发明涉及一种纸张处理装置，其特征在于，包括：片材叠层部，层叠有片材; 用于输送堆叠在纸张堆叠部分上的纸张的纸张输送路径; 纸张输送机，用于将堆叠在纸张堆叠部分上的纸张输送到纸张传送路径; 以及用于折叠片材输送路径中的片材的片材折叠装置。片材折叠装置设置在片材输送路径中，并且片材折页装置所在的片材输送路径的至少一部分形成为弯曲形状。

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