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1. 发明专利

JP2009080047A Evaluating device and method of spect imaging system 有权
标题翻译：评价装置和影像成像系统的方法
公开(公告)号：JP2009080047A
公开(公告)日：2009-04-16
申请号：JP2007250145
申请日：2007-09-26
申请人： Fujifilm Ri Pharma Co Ltd , 富士フイルムRiファーマ株式会社
发明人： KATAFUCHI TETSURO , ONOGUCHI MASAHISA , YOSHIOKA KATSUNORI
IPC分类号： G01T1/161 , G01T7/00
摘要： PROBLEM TO BE SOLVED: To quantitatively evaluate characteristics of an SPECT imaging system.
SOLUTION: The evaluating device 100 of the SPECT imaging system comprises: a storage part 114 of image data of an SPECT image, in which a phantom having a reagent space in which a predetermined liquid reagent containing RI flows and a plurality of defect regions with volumes different from each other is imaged by an evaluation subject SPECT imaging system 180; a storage part 112 of template data indicating a shape of the phantom; a standardization processing part 116 for standardizing the SPECT image based on a template; and an image analysis part 118 for calculating an evaluation index indicating the characteristics of the evaluation subject SPECT imaging system, based on image data of a part corresponding to the respective defect regions in the standardized SPECT image.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：定量评估SPECT成像系统的特性。解决方案：SPECT成像系统的评估装置100包括：SPECT图像的图像数据的存储部114，其中具有其中包含RI的预定液体试剂流动的试剂空间的幻像和多个缺陷体积彼此不同的区域由评估对象SPECT成像系统180成像; 指示体模形状的模板数据的存储部分112; 标准化处理部分116，用于基于模板标准化SPECT图像; 以及图像分析部118，其基于与标准化SPECT图像中的各个缺陷区域对应的部分的图像数据，计算表示评价对象SPECT成像系统的特征的评价指标。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2008216110A Analyzer and method of inspection by split dose method 有权
标题翻译：分析仪和分析方法检验方法
公开(公告)号：JP2008216110A
公开(公告)日：2008-09-18
申请号：JP2007055454
申请日：2007-03-06
申请人： Fujifilm Ri Pharma Co Ltd , 富士フイルムRiファーマ株式会社
发明人： NAKADA SHIGERU , YAMAMOTO NAOYUKI , TAKAHASHI YOSHITAKE , YOSHIOKA KATSUNORI
IPC分类号： G01T1/161
摘要： PROBLEM TO BE SOLVED: To analyze the inspection result by using only images photographed during inspection by a split dose method.
SOLUTION: An analyzer of inspection by the split dose method includes: a storing part 11 of rest images; a storing part 13 of load images based on radiation radiated from the same part of the same subject after giving RI; a radiation intensity ratio calculation part 15 for calculating a radiation intensity ratio of the rest images and the load images based on the rest images and the load images; and a change rate calculation part 17 classified by pixels for calculating the change rate of the load images to the rest images by removing influence due to a difference of the radiation intensity between a rest time and a load time based on the radiation intensity ratio.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：通过仅使用分批剂量法检查期间拍摄的图像来分析检查结果。解决方案：通过分割剂量法检查的分析仪包括：静止图像的存储部分11; 在给出RI之后，基于从相同被摄体的同一部分辐射的辐射的负载图像的存储部分13; 辐射强度比计算部15，用于基于静止图像和负载图像计算静止图像和负载图像的辐射强度比; 以及由像素分类的变化率计算部分17，用于通过基于辐射强度比来消除由于休息时间和加载时间之间的辐射强度的差异造成的负载图像与其余图像的变化率的变化率。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2014048127A Image processing program, recording medium, image processor, and image processing method 有权
标题翻译：图像处理程序，记录介质，图像处理器和图像处理方法
公开(公告)号：JP2014048127A
公开(公告)日：2014-03-17
申请号：JP2012190641
申请日：2012-08-30
申请人： Fujifilm Ri Pharma Co Ltd , 富士フイルムRiファーマ株式会社
发明人： ONOGUCHI MASAHISA , TAKENAKA KENICHI , YOSHIOKA KATSUNORI
IPC分类号： G01T1/161
摘要： PROBLEM TO BE SOLVED: To provide an interpreting technician with information so as to compare images with high accuracy even when imaging conditions for the images formed by imaging a distribution state of radioactive pharmaceutical in the body of a subject are different from each other.SOLUTION: An image processing program for an image processor body 10 that stores an image obtained by capturing a distribution state of radioactive pharmaceutical in the body of a subject causes the image processor body 10 to execute: a selection step for selecting a specific area of a soft tissue in the image; and a normalization step for calculating a reference value showing a pixel value in the specific area to normalize the image on the basis of a value obtained by subtracting the reference value from the pixel value in the image.
摘要翻译：要解决的问题：为了向解释技术人员提供信息，以便即使在通过成像放射性药物在被检体体内的分布状态而形成的图像的成像条件彼此不同的情况下，也可以高精度地比较图像。解决方案：用于存储通过拍摄放射性药物在被检体内的分布状态而获得的图像的图像处理器主体10的图像处理程序使得图像处理器主体10执行：选择步骤，用于选择软组织的特定区域在形象上以及归一化步骤，用于计算表示特定区域中的像素值的参考值，以基于从图像中的像素值减去参考值获得的值来归一化图像。

4. 发明专利

JP2011047834A Cerebral blood flow quantification program, recording medium, and cerebral blood flow quantification method 有权
标题翻译：脑血流量定量方案，记录中和小脑血流量定量法
公开(公告)号：JP2011047834A
公开(公告)日：2011-03-10
申请号：JP2009197482
申请日：2009-08-27
申请人： Fujifilm Ri Pharma Co Ltd , 富士フイルムRiファーマ株式会社
发明人： NAKAMURA SEIJI , KIKUCHI TAKANORI , SHINDO YASUSHI , MASUHARA AKIRA , TAKAHASHI YOSHITAKE , YOSHIOKA KATSUNORI
IPC分类号： G01T1/161
摘要： PROBLEM TO BE SOLVED: To provide a cerebral blood flow quantification program and the like that can determine the accurate cerebral blood flow using the values of radiation counts obtained in a minimally invasive or noninvasive and simple method in determining the cerebral blood flow through the cerebral blood flow SPECT using a divided dose method.
SOLUTION: The value of radiation counts of a sample obtained from one-point venous blood sampling after 55 minutes from a first dose of a medicine (
123 I-IMP) and multiple values of radiation counts in a brain are used as explanatory variables to derive a multiple regression expression having the partial regression coefficient obtained from the multiple regression analysis using the pre-recorded values of radiation counts in arterial blood as an object variable. Entered values of radiation counts in the brain of a subject are applied to the derived multiple regression expression to estimate the value of radiation counts in arterial blood that can be observed by the MS method-based 6-minute duration arterial blood drawing for the subject. The cerebral blood flow of the subject is calculated based on the entered values of radiation counts in the brain and the estimated radioation count in arterial blood.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供可以使用在微创或非侵入性和简单方法中获得的辐射计数的值来确定脑血流量的脑血流量定量程序等来确定脑血流量脑血流SPECT采用分次剂量法。解决方案：从第一次药物剂量（ 123 I-IMP）55分钟后从一点静脉采血获得的样品的辐射计数值和多个辐射计数值在大脑中用作解释变量来导出具有使用动脉血中预先记录的辐射计数值作为对象变量从多元回归分析获得的部分回归系数的多元回归表达式。将受试者脑中辐射计数的输入值应用于导出的多元回归表达，以估计通过基于MS方法的6分钟持续时间动脉血液绘图对动物血液中的辐射计数的值。基于大脑中辐射计数的输入值和动脉血中估计的放射线计数计算受试者的脑血流量。版权所有（C）2011，JPO＆INPIT

5. 发明专利

JP2008246002A Estimation program, recording medium, and estimation method 有权
标题翻译：估计程序，记录介质和估计方法
公开(公告)号：JP2008246002A
公开(公告)日：2008-10-16
申请号：JP2007092445
申请日：2007-03-30
申请人： Fujifilm Ri Pharma Co Ltd , 富士フイルムRiファーマ株式会社
发明人： FUKUNAGA HITOO , SONE TERUYOSHI , MIMURA HIROO , TAKAHASHI YOSHITAKE , YOSHIOKA KATSUNORI
IPC分类号： A61B6/03 , G01T1/161
CPC分类号： A61B6/507
摘要： PROBLEM TO BE SOLVED: To provide an estimation program, etc., for allowing a computer to estimate a radioactive concentration in an arterial blood cutoff, which is fractionated by using a prescribed solvent with sufficient measurement precision, etc., and to estimate a local brain blood flow, without neither necessity to use a highly precise sustained blood collection pump nor invasiveness and operational complication in a case, etc., where the blood is continuously collected by indwelling a blood collection tube in an artery.
SOLUTION: The radioactive concentration in the venous blood, which is measured after administering a brain blood flow tracer, the radioactive concentration in the venous blood cutoff, which is fractionated by using the prescribed solvent, and the two temporal radiation counts of the whole brain, which are measured after prescribed first and second times elapsed, are inputted. The radioactive concentration in an artery blood octanol cutoff, which seems to be measured after administering the blood flow tracer, is estimated based on the above data. The local brain blood flow is estimated based on the estimated radioactive concentration in the artery blood octanol cutoff.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于允许计算机估计通过使用具有足够的测量精度等的规定溶剂分级的动脉血液截断中的放射性浓度的估计程序等，并且估计局部脑血流量，而不需要使用高度精确的持续采血泵，也不需要在病例等中进行侵袭性和手术并发症，其中通过将动脉中的采血管留置血液来连续收集血液。解决方案：在施用脑血流示踪剂后测量的静脉血中的放射性浓度，通过使用规定的溶剂分馏的静脉血液截留中的放射性浓度和两次的时间辐射计数输入经过规定的第一次和第二次之后测量的全脑。基于上述数据估计在施用血液流动示踪剂之后似乎测量的动脉血液辛醇截止值中的放射性浓度。根据动脉血中辛烷值的估计放射性浓度估计局部脑血流量。版权所有（C）2009，JPO＆INPIT

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