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1. 发明授权

US5578494A Cap actuator for opening and closing a container 失效
标题翻译：用于打开和关闭容器的盖致动器
公开(公告)号：US5578494A
公开(公告)日：1996-11-26
申请号：US600321
申请日：1996-02-13
申请人： Frederic L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
发明人： Frederic L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , B65D51/04
CPC分类号： B01L3/08 , B01F11/0022 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10T436/11 , Y10T436/113332 , Y10T436/119163
摘要： The present invention is a method for opening and closing a cap pivotally mounted on a container for storing reagents for use in an automated analytical instrument. The cap has one end for sealing the container and a tab extending from the other end for pivoting the cap. The method comprises the steps of positioning a closed container adjacent an actuating device mounted on the analytical system. The method further comprises the steps of projecting the actuating device against the top of the tab to pivotally open the cap to a position sufficiently vertical for aspirating reagent from the container, and retracting the actuating device from the cap to a position above the pivotal mounting thereof. The method comprises the final step of causing relative motion between the cap and the actuating device so that the actuating device drags along the top of the cap pivotally closing the cap to provide a sufficient seal on the container preventing evaporation of the reagent therefrom.
摘要翻译：本发明是一种用于打开和关闭枢转地安装在用于存储用于自动分析仪器的试剂的容器上的盖的方法。盖具有用于密封容器的一端和从另一端延伸以突出盖的突片。该方法包括以下步骤：将密封容器定位在安装在分析系统上的致动装置附近。该方法还包括以下步骤：将致动装置突出于突片的顶部，以将帽旋转到足够垂直的位置以从容器吸出试剂，并将致动装置从帽缩回到其枢转安装件上方的位置。该方法包括在帽和致动装置之间引起相对运动的最后步骤，使得致动装置沿着盖的顶部拖动，枢转地闭合盖，以在容器上提供足够的密封，防止试剂从其中蒸发。

2. 发明授权

US5376313A Injection molding a plastic assay cuvette having low birefringence 失效
标题翻译：注射成型具有低双折射率的塑料分析试管
公开(公告)号：US5376313A
公开(公告)日：1994-12-27
申请号：US915162
申请日：1992-07-20
申请人： William J. Kanewske, III , James A. Vaught , Richard L. Vickstrom , Frederic L. Clark , Gilbert Clift , Kendall B. Hendrick , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry E. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , David A. Yost
发明人： William J. Kanewske, III , James A. Vaught , Richard L. Vickstrom , Frederic L. Clark , Gilbert Clift , Kendall B. Hendrick , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry E. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , David A. Yost
IPC分类号： G01N21/64 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/27 , G01N21/49 , G01N21/59 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
CPC分类号： H01J49/04 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1065 , Y10S435/809 , Y10S436/807 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A plastic assay cuvette having the desired optical properties for the analysis of a test sample or reaction mixture thereof, and a method for making such plastic assay cuvette, are described. The optical properties of the plastic assay cuvette are substantially the same as the optical properties of glass wherein low birefringence throughout the optical read region thereof is provided. When used for the analysis of a test sample or reaction mixture thereof, such as in fluorescence polarization assays and absorbance assays, the plastic assay cuvette provides accurate and reproducible results while, at the same time, provides a low-cost disposable assay cuvette which can be used in place of conventional glass assay cuvettes.
摘要翻译：描述了具有用于分析测试样品或其反应混合物的所需光学性质的塑料分析比色皿以及制备这种塑料分析比色杯的方法。塑料分析试管的光学性质与玻璃的光学性质基本相同，其玻璃的光学读取区域的双折射率低。当用于分析测试样品或其反应混合物时，例如在荧光偏振测定和吸光度测定中，塑料分析比色杯提供精确和可重现的结果，同时提供了一种低成本的一次性分析比色杯，其可以用于代替常规玻璃分析比色皿。

3. 发明授权

US5358691A Automated continuous and random access analytical system 失效
标题翻译：自动连续随机存取分析系统
公开(公告)号：US5358691A
公开(公告)日：1994-10-25
申请号：US126447
申请日：1993-09-24
申请人： Frederic L. Clark , Gilbert Clift , Kendall B. Hendrick , William J. Kanewske, III , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry W. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , James A. Vaught , David A. Yost
发明人： Frederic L. Clark , Gilbert Clift , Kendall B. Hendrick , William J. Kanewske, III , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry W. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , James A. Vaught , David A. Yost
IPC分类号： G01N21/64 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/27 , G01N21/49 , G01N21/59 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N35/06
CPC分类号： H01J49/04 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1065 , Y10S435/809 , Y10S436/807 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable to a processing workstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
摘要翻译：一种自动化，连续和随机存取分析系统，其具有能够使用不同测定方法同时进行液体样品的多个测定的装置和方法，并且在相同或不同样品的同一或不同样品上进行多个不同测定时间段被披露。还公开了一种操作自动连续和随机存取分析系统的方法，其能够同时进行多个液体样品的多次测定，其中多个液体样品的各种测定的调度之后是产生单位剂量一次性并分别转移将第一液体样品和试剂加入到反应容器中，而不引发测定反应顺序，随后将单位剂量一次性物理转移到加工工作站，由此在孵育期间实现单位剂量的一次性试剂和样品的混合物。该系统能够以任何顺序执行多于一次的计划分析，以及多于此类计划测定的测定。自动，连续和随机存取分析系统还能够通过至少两种测定程序独立地和单独地分析温育的反应混合物。

4. 发明授权

US5482861A Automated continuous and random access analytical system 失效
标题翻译：自动连续随机存取分析系统
公开(公告)号：US5482861A
公开(公告)日：1996-01-09
申请号：US222520
申请日：1994-04-04
申请人： Frederic L. Clark , Gilbert Clift , Kendall B. Hendrick , William J. Kanewske, III , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry W. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , James A. Vaught , David A. Yost
发明人： Frederic L. Clark , Gilbert Clift , Kendall B. Hendrick , William J. Kanewske, III , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry W. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , James A. Vaught , David A. Yost
IPC分类号： G01N21/64 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/27 , G01N21/49 , G01N21/59 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
CPC分类号： H01J49/04 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1065 , Y10S435/809 , Y10S436/807 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable to a processing workstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
摘要翻译：一种自动化，连续和随机存取分析系统，其具有能够使用不同测定方法同时进行液体样品的多个测定的装置和方法，并且在相同或不同样品的同一或不同样品上进行多个不同测定时间段被披露。还公开了一种操作自动连续和随机存取分析系统的方法，其能够同时进行多个液体样品的多次测定，其中多个液体样品的各种测定的调度之后是产生单位剂量一次性并分别转移将第一液体样品和试剂加入到反应容器中，而不引发测定反应顺序，随后将单位剂量一次性物理转移到加工工作站，由此在孵育期间实现单位剂量的一次性试剂和样品的混合物。该系统能够以任何顺序执行多于一次的计划分析，以及多于此类计划测定的测定。自动，连续和随机存取分析系统还能够通过至少两种测定程序独立地和单独地分析温育的反应混合物。

5. 发明授权

US5451528A Methods for providing homogeneous reagents 失效
标题翻译：提供均相试剂的方法
公开(公告)号：US5451528A
公开(公告)日：1995-09-19
申请号：US916737
申请日：1993-08-20
申请人： William J. Raymoure , Frederic L. Clark , Gibert Clift , Kendall B. Hendrick , William J. Kanewske, III , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry E. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , James A. Vaught , David A. Yost
发明人： William J. Raymoure , Frederic L. Clark , Gibert Clift , Kendall B. Hendrick , William J. Kanewske, III , Peter A. Lagocki , Richard R. Martin , James E. Mitchell , Larry E. Moore , Charles D. Pennington , Edna S. Walker , B. Jane Smith , Apparao Tayi , James A. Vaught , David A. Yost
IPC分类号： G01N21/64 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/27 , G01N21/49 , G01N21/59 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N33/546
CPC分类号： H01J49/04 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1065 , Y10S435/809 , Y10S436/807 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A method for modifiying a liquid assay reagent to provide prolonged homogeneity thereof, particularly where the liquid assay reagent comprises microparticles for performing a heterogeneous immunoassay, is provided wherein the addition of an inert material to a liquid assay reagent achieves neutral density to thereby prolong the homogeneity thereof for extended periods of time. A method for the automated agitation of assay reagents to maintain the homogeneity thereof with an automated, continuous and random access analytical instrument is also provided. The automated mixing is accomplished by a back and forth motion of a carousel onto which assay reagent containers or packs are mounted with asymmetric pauses which can be completed within a short period of time. The carousel acceleration, velocity, distance moved, and pause-asymmetry are optimized to provide rapid assay reagent resuspension without foaming or bubble formation. Accordingly, periodic removal of assay reagent packs by an operator in order to mix the reagents is not necessary.
摘要翻译：提供了一种用于修饰液体测定试剂以提供其延长的均匀性的方法，特别是在液体测定试剂包含用于进行非均相免疫测定的微粒的情况下，其中向液体测定试剂中加入惰性物质达到中性密度从而延长均匀性延长时间。还提供了一种用于自动搅拌测定试剂以保持其与自动化，连续和随机存取分析仪器的均匀性的方法。自动化混合是通过旋转木马的来回运动完成的，在该转盘上，分析试剂容器或包装件以不对称的停顿方式安装在该转盘上，可以在短时间内完成。旋转木马加速度，速度，移动距离和暂停不对称性被优化，以提供快速的测定试剂重悬浮而没有起泡或气泡形成。因此，为了混合试剂，由操作者定期去除测定试剂包是不必要的。

6. 发明授权

US5960160A Liquid heater assembly with a pair temperature controlled electric heating elements and a coiled tube therebetween 失效
标题翻译：具有对温度控制的电加热元件和其间的盘管的液体加热器组件
公开(公告)号：US5960160A
公开(公告)日：1999-09-28
申请号：US581884
申请日：1995-12-28
申请人： Frederic L. Clark , Richard R. Martin , Larry W. Moore , John M. Clemens , William D. Rumbaugh , B. Jane Smith
发明人： Frederic L. Clark , Richard R. Martin , Larry W. Moore , John M. Clemens , William D. Rumbaugh , B. Jane Smith
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , G01N21/25 , G01N21/64 , G01N35/00 , G01N35/02 , G01N35/04 , H01J49/04 , F24H1/00 , A61F7/00
CPC分类号： B01L3/5025 , B01F11/0022 , B01L3/08 , G01N21/253 , G01N21/645 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , G01N2021/6482 , G01N2035/00356 , G01N2035/0093 , G01N2035/0405 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0453
摘要： A liquid heater assembly including a heater body having therein a coiled tube for passing liquids, a pair of heating elements, a thermistor, a thermostat, and a backup thermostat. Liquid enters the coiled liquid tube at an inlet end and exits the coiled liquid tube at an outlet end. The coiled liquid tube is positioned within the heater body between the pair of heating elements. The outlet end extends below a planar surface of the heater body. The thermistor detects the temperature changes of the heater body. The resistance of the thermistor is used to regulate the supply of power to the heating elements. The thermostat and the backup thermostat are connected in series between the power source and the heating elements to provide a safety shutoff when the heater body reaches a predetermined overheat temperature. The heater body is maintained at a predetermined temperature by regulating the electrical current to the heating elements. A receptacle can be placed in close proximity below the outlet end to minimize the air gap between the two parts. Liquid passing through the heater assembly can be delivered at a precise temperature to the receptacle below the heater assembly.
摘要翻译：一种液体加热器组件，其包括其中具有用于通过液体的盘管的加热器主体，一对加热元件，热敏电阻，恒温器和备用恒温器。液体在入口端进入盘管液管，并在出口端离开卷绕的液体管。盘管液体管位于加热器本体内的一对加热元件之间。出口端部延伸到加热器主体的平坦表面的下方。热敏电阻检测加热器体的温度变化。热敏电阻的电阻用于调节对加热元件的供电。恒温器和备用恒温器在电源和加热元件之间串联连接，以在加热器体达到预定的过热温度时提供安全关闭。通过调节加热元件的电流将加热器体维持在预定温度。容器可以靠近出口端放置，以最小化两部分之间的气隙。通过加热器组件的液体可以在精确的温度下被输送到加热器组件下面的容器中。

7. 发明授权

US5605665A Reaction vessel 失效
标题翻译：反应容器
公开(公告)号：US5605665A
公开(公告)日：1997-02-25
申请号：US176430
申请日：1994-01-03
申请人： Frederic L. Clark , Larry W. Moore , William J. Kanewske, III , Douglas D. McDowell , Gilbert Clift
发明人： Frederic L. Clark , Larry W. Moore , William J. Kanewske, III , Douglas D. McDowell , Gilbert Clift
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
CPC分类号： B01F11/0022 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10T436/11 , Y10T436/113332 , Y10T436/114165
摘要： A reaction vessel having a platform and a plurality of wells extending below the platform from openings in the platform. A support skirt extending below the platform by an opening therein, secures a cuvette to the reaction vessel. At the rear of the reaction vessel, a reaction vessel tab is disposed below the reaction vessel for facilitating transport of the reaction vessel through the automated analytical system.
摘要翻译：一种反应容器，具有平台和从该平台中的开口延伸到平台下方的多个井。通过其中的开口在平台下方延伸的支撑裙，将比色皿固定到反应容器。在反应容器的后部，在反应容器的下方设置反应容器片，以便于反应容器通过自动分析系统的输送。

8. 发明授权

US5536471A Syringe with bubble flushing 失效
标题翻译：注射器与气泡冲洗
公开(公告)号：US5536471A
公开(公告)日：1996-07-16
申请号：US176752
申请日：1994-01-03
申请人： Frederic L. Clark , Richard R. Martin , Donny R. Walker
发明人： Frederic L. Clark , Richard R. Martin , Donny R. Walker
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , B01L3/02
CPC分类号： G01N21/6445 , B01F11/0022 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10T436/119163 , Y10T436/2575
摘要： A bubble flushing syringe for aspirating and dispensing fluids through an open-ended tip with precision and volumetric accuracy is disclosed. The syringe comprises a piston within a bore formed by a generally cylindrical wall having a closed end and an open end, wherein the piston forms an annulus with the wall and closed end of the bore, and is capable of reciprocating therein. The syringe further comprises an annular seal seated in the open end of the bore and circumventing the piston to close the annulus sufficiently snug to retain fluid when the piston reciprocates therethrough. An inlet for directing fluid to the annulus through the wall of the bore and an outlet for directing fluid from the annulus through the wall of the bore to the open-ended tip are positioned proximal to the annular seal and the line generally axially therebetween. A drive device is connected to the piston for reciprocating the piston within the bore. As a result, fluid from the inlet, when connected to a fluid supply, flows around the piston and through the outlet to the open-ended tip, thereby creating a cross-flow pattern in the annulus around the piston as it reciprocates in the bore to flush bubbles through the outlet.
摘要翻译：公开了一种气泡冲洗注射器，用于通过开口端头精确和体积精度吸入和分配流体。注射器包括在由具有封闭端和开口端的大致圆柱形壁形成的孔内的活塞，其中活塞与孔的壁和封闭端形成环形并且能够在其中往复运动。注射器还包括安置在孔的开口端中的环形密封件，并围绕活塞，以在活塞从其中往复运动时充分紧贴闭环以保持流体。用于将流体引导通过孔的壁的入口和用于将流体从环通过孔的壁引导到开口端的出口被定位在环形密封件的近侧，并且线在其之间大致轴向地定位。驱动装置连接到活塞，用于使活塞在孔内往复运动。结果，来自入口的流体当连接到流体源时流过活塞并通过出口流到开口端，从而在活塞周围的环中产生横流模式，当其在孔中往复运动时以通过出口冲洗气泡。

9. 发明授权

US4453841A Duplex printing system and method therefor 失效
标题翻译：双面打印系统及其方法
公开(公告)号：US4453841A
公开(公告)日：1984-06-12
申请号：US355423
申请日：1982-03-08
申请人： Thomas W. Bobick , Frederic L. Clark , Henry W. Jongerling , Barry C. Kockler , Svetislav Mitrovich
发明人： Thomas W. Bobick , Frederic L. Clark , Henry W. Jongerling , Barry C. Kockler , Svetislav Mitrovich
IPC分类号： B41J3/60 , H04N1/32 , B41J3/02
CPC分类号： H04N1/32358 , B41J3/60 , Y10S271/902
摘要： A print system for duplex printing a plurality of document page images on a plurality of copy sheets includes means for storing print control information which defines the document images. An ink jet printer prints the page images on copy sheets as they are transported past a print station by a transport arrangement defining a closed sheet path. The sheet path is of sufficient length such that a number of copy sheets are transported simultaneously therethrough. A copy sheet inverter receives copy sheets sequentially from the sheet path after the sheets are printed on their first sides and returns them to the sheet path in an inverted orientation prior to printing on the second sides of the copy sheets.
摘要翻译：用于在多个复印纸上双面打印多个文档页面图像的打印系统包括用于存储定义文档图像的打印控制信息的装置。喷墨打印机通过定义封闭纸张路径的传送装置将纸张图像打印在复印纸上，因为它们被传送通过印刷站。片材路径具有足够的长度，使得多个复印纸被同时传送通过。复印纸变换器在纸张在其第一面上打印之后从纸张路径依次接收复印纸，并且在打印在复印纸的第二面上之前将纸张路径以反方向返回到纸张路径。

10. 发明授权

US4404566A Fluid system for fluid jet printing device 失效
标题翻译：流体喷射印刷装置用流体系统
公开(公告)号：US4404566A
公开(公告)日：1983-09-13
申请号：US355421
申请日：1982-03-08
申请人： Frederic L. Clark , Scott D. Ayers
发明人： Frederic L. Clark , Scott D. Ayers
IPC分类号： B41J2/17 , G01D15/18
CPC分类号： B41J2/1707
摘要： An ink jet fluid system and process of startup and shutdown is provided which includes a print head having a fluid manifold and at least one orifice for forming a jet drop printing stream. Inlet and outlet valves are connected to inlet and outlet openings of the print head. During shutdown, fluid is continuously circulated around the print head through a bypass line while the outlet of the print head is connected to a source of reduced pressure to prevent fluid from flowing through the orifice. At startup, the inlet and outlet valves are actuated to provide a continuous flow of fluid under pressure to the print head. In another embodiment of the invention, a fluid system is provided for a multiple print head device and provides for independent control of the fluid pressure in each print head.
摘要翻译：提供一种喷墨流体系统和启动和关闭的过程，其包括具有流体歧管的打印头和用于形成喷射液滴印刷流的至少一个孔口。入口和出口阀连接到打印头的入口和出口。在关闭期间，流体通过旁路管线在打印头周围连续循环，同时打印头的出口连接到减压源以防止流体流过孔口。在启动时，进口和出口阀被致动以在压力下向印刷头提供连续的流体流。在本发明的另一个实施例中，为多打印头装置提供流体系统，并提供对每个打印头中的流体压力的独立控制。

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