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1. 发明授权

US5193525A Antiglare tip in a sheath for an endoscope 失效
标题翻译：用于内窥镜的护套中的防斜纹尖端
公开(公告)号：US5193525A
公开(公告)日：1993-03-16
申请号：US620488
申请日：1990-11-30
申请人： Fred E. Silverstein , Eric A. Opie, deceased , David R. Kreft , Bandula Wijay
发明人： Fred E. Silverstein , Eric A. Opie, deceased , David R. Kreft , Bandula Wijay
IPC分类号： A61B1/00
CPC分类号： A61B1/00174 , A61B1/00096 , A61B1/00101 , A61B1/0011 , A61B1/00142 , Y10S600/92
摘要： An antiglare tip for the sheath of an endoscope to prevent glare in an image viewer is disclosed. The antiglare tip includes an interfitting region with the endoscope to ensure that all light entering the image viewer is reflected from objects external to the endoscope. An opaque projection extends from the endoscope insertion tube between the light source and the image viewer. Opaque recesses in the tip are positioned to mate with the opaque projections extending from the endoscope end. Having mating projections and recesses aligned ensures that no light may pass directly from the light source to the image viewer via the tip. Glare resulting from internal reflections in the tip, or from an inside surface of the tip, is prevented.
摘要翻译：公开了一种用于内窥镜护套的防眩光尖端以防止图像观察者中的眩光。防眩光尖端包括与内窥镜的配合区域，以确保进入图像观看者的所有光从内窥镜外部的物体反射。不透明突起从光源和图像观察者之间的内窥镜插入管延伸。尖端中的不透明凹槽定位成与从内窥镜端延伸的不透明凸起配合。使匹配的突起和凹槽对准确保了光线不能通过尖端直接从光源传递到图像观察者。防止了尖端内部反射或从尖端的内表面引起的眩光。

2. 发明授权

US5025778A Endoscope with potential channels and method of using the same 失效
标题翻译：具有潜在通道的内窥镜及其使用方法
公开(公告)号：US5025778A
公开(公告)日：1991-06-25
申请号：US498611
申请日：1990-03-26
申请人： Fred E. Silverstein , Eric A. Opie, deceased
发明人： Fred E. Silverstein , Eric A. Opie, deceased
IPC分类号： A61B1/00 , A61B1/015 , A61B1/018 , A61B1/04 , A61B8/12 , A61B10/00 , A61B10/04 , A61B17/00 , A61B17/22 , A61B17/34 , A61B18/24 , A61B19/00
CPC分类号： A61B1/0008 , A61B1/00135 , A61B1/00142 , A61B1/015 , A61B1/018 , A61B1/042 , A61B8/12 , A61B8/4416 , A61B10/04 , A61B17/22012 , A61B18/245 , A61B2017/00438 , A61B2017/3445 , A61B34/70
摘要： An apparatus and method for providing an endoscope with a plurality of potential channels is disclosed. A tubing having a radially flexible wall is positioned adjacent the endoscope insertion tube. The tubing is collapsed prior to inserting the insertion tube into the patient's body. After the insertion tube is within the patient's body, the tubing is expanded to create a channel. A medical apparatus may pass through the channel for performing a medical procedure. The tubing is expanded by placing a tapered rod therethrough, by placing a fluid under pressure within the tubing, or by elevating a flat coiled wire into a cylindrical coil. A radially rigid tubing is placed within the expanded flexible tubing to permit medical devices to extend from a position outside of the patient's body to the distal end of the insertion tube. A plurality of tubings are provided circumferentially spaced from each other around the insertion tube to permit a combination of medical devices to be used in cooperation with each other to perform a medical procedure. A stiffening member, such as a rod or fluid under pressure may extend partially along the length of the insertion tube to vary the flexibility characteristics of the insertion tube while it is within the patient's body.
摘要翻译：公开了一种用于为内窥镜提供多个潜在通道的装置和方法。具有径向柔性壁的管道邻近内窥镜插入管定位。在将插入管插入患者体内之前，管子被折叠。在插入管位于患者体内之后，将管道扩张以形成通道。医疗器械可以通过用于执行医疗程序的通道。通过将压力下的流体放置在管内，或者通过将扁平的盘绕的线提升到圆柱形线圈中，通过将锥形杆放置在其中而使其膨胀。径向刚性管道放置在膨胀的柔性管道内，以允许医疗装置从患者身体外部的位置延伸到插入管的远端。多个管道围绕插入管周向间隔设置，以允许彼此配合使用的医疗装置的组合以执行医疗程序。加压构件，例如压力下的杆或流体可以沿插入管的长度部分地延伸，以在插入管位于患者身体内时改变插入管的柔性特性。

3. 再颁专利

USRE34110E Endoscope for use with a disposable sheath 失效
公开(公告)号：USRE34110E
公开(公告)日：1992-10-27
申请号：US727224
申请日：1991-06-25
申请人： Eric A. Opie, deceased , Fred E. Silverstein
发明人： Eric A. Opie, deceased , Fred E. Silverstein
IPC分类号： A61B1/00 , A61B1/005 , A61B1/04
CPC分类号： A61B1/042 , A61B1/00071 , A61B1/00073 , A61B1/00142 , A61B1/00165 , A61B1/0055
摘要： An endoscope specially adapted for use with a disposable sheath having an outer casing and one or more internal channels. The endoscope includes a tip portion connected to a control handle through a flexible insertion tube. The insertion tube is formed by a braided wire tube covered by a flexible waterproof coating and surrounding a resilient D-shaped tube through which optical components for the endoscope extend. A longitudinally extending groove is formed in the braided tube to receive and channel(s). The groove extends perpendicular to, and makes contact with, a generally planar portion of the D-shaped tube so that the D-shaped tube can restrict deformation of the groove as the insertion tube bends. Longitudinal channels are formed on opposite sides of the groove to house control cables extending from the control handle to the tip portion. The cables are surrounded by tubes that collectively occupy the entire channel so that the tubes prevent the channel, and hence the groove, from collapsing.

4. 发明授权

US4947827A Flexible endoscope 失效
标题翻译：柔性内窥镜
公开(公告)号：US4947827A
公开(公告)日：1990-08-14
申请号：US292473
申请日：1988-12-30
申请人： Eric Opie, deceased , Fred E. Silverstein , David R. Kreft
发明人： Eric Opie, deceased , Fred E. Silverstein , David R. Kreft
IPC分类号： G02B23/24 , A61B1/00 , A61B1/005
CPC分类号： A61B1/00073 , A61B1/0052
摘要： Various methods and mechanical devices for providing manipulation and steering of the bending section of an endoscope having a sheath thereon is disclosed. In one embodiment, the longitudinal center axis of a biopsy type is aligned with the longitudinal center of the insertion tube, both being in common with the instantaneous bending center of the insertion tube. The insertion tube is capable of only right and left movement through steering but is also rotatable with respect to the handle to permit the tip to be positioned in any desired location. In an alternative embodiment, the instantaneous bending center is radially offset from the longitudinal center of the insertion tube. The hinges are positioned in the bending section of the insertion tube for locating the instantaneous center of bending at a desired location in a groove. Four, or in an alternative embodiment, three cables are provided for controlling the movement and steering of the bending section. Because the cables are not symmetrically located with respect to the instantaneous bending center, the mechanical control assembly is designed to take into account the difference between the movements of the respective cable through the full range of motions. In an alternative embodiment, the channel is located radially offset from the instantaneous center of bending and the biopsy tube assembly is made stretchable or compressible to ensure that the biopsy tube end remains aligned with the end of the insertion tube end.
摘要翻译：公开了用于提供具有护套的内窥镜的弯曲部分的操纵和转向的各种方法和机械装置。在一个实施例中，活检类型的纵向中心轴线与插入管的纵向中心对准，两者都与插入管的瞬时弯曲中心相同。插入管能够仅通过转向左右移动，但也可相对于手柄旋转，以允许尖端定位在任何期望的位置。在替代实施例中，瞬时弯曲中心从插入管的纵向中心径向偏移。铰链定位在插入管的弯曲部分中，用于将瞬时的弯曲中心定位在凹槽中的期望位置。四个或替代实施例中，提供三根电缆以控制弯曲部分的移动和转向。由于电缆相对于瞬时弯曲中心不对称地定位，所以机械控制组件被设计成考虑到各个电缆通过全部运动范围的运动之间的差异。在替代实施例中，通道位于径向偏离瞬时弯曲中心的位置，活检管组件被制成可拉伸或可压缩，以确保活检管端部保持与插入管端部的端部对准。

5. 发明授权

US09521961B2 Systems and methods for guiding a medical instrument 有权
标题翻译：用于引导医疗器械的系统和方法
公开(公告)号：US09521961B2
公开(公告)日：2016-12-20
申请号：US13336919
申请日：2011-12-23
申请人： Fred E. Silverstein , Robert N. Golden
发明人： Fred E. Silverstein , Robert N. Golden
IPC分类号： A61B5/05 , A61B5/06 , A61B5/042 , A61B5/00 , A61B8/08 , A61B8/00
CPC分类号： A61B5/062 , A61B5/042 , A61B5/743 , A61B5/7475 , A61B8/0833 , A61B8/0841 , A61B8/0891 , A61B8/4472 , A61B8/463 , A61B34/20 , A61B90/37 , A61B90/98 , A61B2034/2051 , A61B2090/374 , A61B2090/378 , A61B2090/3954
摘要： A guidance system for assisting with the insertion of a needle into a patient body is disclosed. The guidance system utilizes ultrasound imaging or other suitable imaging technology. In one embodiment, the guidance system comprises an imaging device including a probe for producing an image of an internal body portion target, such as a vessel. One or more sensors are included with the probe. The sensors sense a detectable characteristic related to the needle, such as a magnetic field of a magnet included with the needle. The system includes a processor that uses data relating to the sensed characteristic to determine a 3-D position of the needle. The system includes a display for depicting the position of the needle. In other embodiments, a guidance system for guiding rigid or other medical instruments is disclosed, together with various example implementations thereof.
摘要翻译：公开了一种用于辅助将针插入患者体内的引导系统。引导系统利用超声成像或其他合适的成像技术。在一个实施例中，引导系统包括成像装置，其包括用于产生诸如血管的内部身体部分目标的图像的探针。探头附带一个或多个传感器。传感器检测与针相关的可检测特性，例如包括在针中的磁体的磁场。该系统包括使用与感测特征有关的数据来确定针的3-D位置的处理器。该系统包括用于描绘针的位置的显示器。在其他实施例中，公开了用于引导刚性或其它医疗器械的引导系统及其各种示例实施方式。

6. 发明授权

US07833280B2 Satiation devices and methods 有权
标题翻译：饱和装置和方法
公开(公告)号：US07833280B2
公开(公告)日：2010-11-16
申请号：US12099290
申请日：2008-04-08
申请人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
发明人： Richard S. Stack , Richard A. Glenn , Trevor J. Moody , Fred E. Silverstein , Nathan Every , William S. Eubanks, Jr.
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F2/07 , A61F2/24 , A61F5/0069 , A61F5/0079 , A61F2002/044 , A61F2002/045 , A61F2002/067 , A61F2002/072 , A61F2002/8483 , A61F2250/0039 , A61F2250/0067
摘要： A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.
摘要翻译：用于在患者中引起体重减轻的装置包括管状假体，该管状假体可从其中假体具有第一直径到扩张位置的可膨胀位置自动扩张，在该位置假体具有第二较大的直径。在用于引起体重减轻的方法中，假体被置于折叠位置并插入患者的胃中。允许假体从折叠位置自身膨胀到扩张位置并与胃的壁接触，其中它引起饱腹感和/或抑制饱腹感调节因子如Ghrelin的调节。

7. 发明授权

US07146984B2 Method and apparatus for modifying the exit orifice of a satiation pouch 有权
标题翻译：用于改变饱和袋的出口的方法和装置
公开(公告)号：US07146984B2
公开(公告)日：2006-12-12
申请号：US10387031
申请日：2003-03-12
申请人： Richard S. Stack , Fred E. Silverstein , Nathan Every , William L. Athas , Michael S. Williams , Richard A. Glenn , John Lunsford , Dan Balbierz
发明人： Richard S. Stack , Fred E. Silverstein , Nathan Every , William L. Athas , Michael S. Williams , Richard A. Glenn , John Lunsford , Dan Balbierz
IPC分类号： A61B19/00 , A61F12/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0079 , A61F5/0089 , A61F2002/044
摘要： A prosthetic device is described that is positionable within the gastro-esophageal junction region of a patient. The prosthetic device includes a proximal opening and a distal orifice that is adjustable in size prior to and/or following implantation. During use, the prosthetic device is attached to tissue of the gastro-esophageal junction region of the patient, with the device positioned such that food ingested by the patient passes from the esophagus through the proximal opening into the interior of the prosthetic device, and eventually exits the prosthetic device via the distal opening.
摘要翻译：描述了可以在患者的胃食管连接区域内定位的假体装置。假体装置包括在植入之前和/或之后尺寸可调节的近端开口和远端口。在使用期间，假体装置附接到患者的胃食管接合区域的组织，其中该装置被定位成使得患者摄取的食物从食道通过近端开口进入假体装置的内部，并且最终通过远端开口离开假体装置。

8. 发明授权

US5229799A Collapsible slide carousel 失效
标题翻译：可折叠幻灯片转盘
公开(公告)号：US5229799A
公开(公告)日：1993-07-20
申请号：US857083
申请日：1992-03-19
申请人： Fred E. Silverstein , Andrew H. Proctor
发明人： Fred E. Silverstein , Andrew H. Proctor
IPC分类号： G03B23/04 , G03B23/06
CPC分类号： G03B23/06 , G03B23/04
摘要： A collapsible slide carousel which allows for more efficient storage and transport thereof. The collapsible slide carousel includes an upper portion, a lower portion and a plurality of slide dividers pivotally secured to the upper and lower portions such that the slides can be positioned in an erect position or a collapsed position. In the erect position the slides are disposed substantially vertically as in a conventional carousel such that the slides can be viewed utilizing a conventional carousel projector. Alternatively, in the collapsed position the slides are disposed in an angular position overlapping one another in a domino-like manner allowing for more efficient storage and transportation of the carousel. The upper portion of the carousel is rotatably disposed with respect to the lower portion such that the carousel can be adjusted from the erect position to the collapsed position, and vice versa, by rotating the upper portion with respect to the lower portion. In the erect position the upper portion is displaced from the lower portion and in the collapsed position the upper portion is disposed adjacent the lower portion. The carousel further include a spring for urging the upper portion away from the lower portion such that the slides are urged toward the erect position.
摘要翻译：可折叠的滑动转盘允许更有效的储存和运输。可折叠的滑动转盘包括上部，下部和可枢转地固定到上部和下部的多个滑动分隔部，使得滑块可以定位在直立位置或收缩位置。在直立位置，滑块基本垂直地布置成如传统的圆盘传送带，使得可以使用传统的圆盘传送带投影仪观看幻灯片。或者，在折叠位置，滑块以相对于彼此重叠的角度位置布置，使得圆盘传送带更有效地存储和运输。转盘的上部相对于下部可旋转地设置，使得圆盘传送带可以通过相对于下部旋转上部，从直立位置到折叠位置，反之亦然。在直立位置，上部从下部移位，并且在折叠位置，上部邻近下部设置。转盘还包括用于将上部部分推离远离下部的弹簧，使得滑块朝着直立位置被推动。

9. 发明授权

US4802487A Endoscopically deliverable ultrasound imaging system 失效
标题翻译：内窥镜可交付超声成像系统
公开(公告)号：US4802487A
公开(公告)日：1989-02-07
申请号：US30898
申请日：1987-03-26
申请人： Roy W. Martin , Fred E. Silverstein
发明人： Roy W. Martin , Fred E. Silverstein
IPC分类号： A61B8/12 , A61M25/00 , A61M25/01 , A61B10/00
CPC分类号： A61M25/0122 , A61B8/12 , A61B8/445 , A61M25/005
摘要： An endoscopically deliverable ultrasound imaging system having an ultrasound probe mounted at the end of an endoscopically deliverable catheter. The catheter connects the probe to an ultrasound imaging system. The axial or radial position of the ultrasound probe is measured by a position transducer mounted on the endocscope adjacent the biopsy port from which the catheter extends. The output of the position measuring transducer is applied to the ultrasound imaging system so that the imaging system provides an image of the tissue depth as a function of the position of the ultrasound probe.

10. 发明授权

US4770185A Method and apparatus for endoscopic blood flow detection by the use of ultrasonic energy 失效
标题翻译：通过使用超声能量进行内窥镜血流检测的方法和装置
公开(公告)号：US4770185A
公开(公告)日：1988-09-13
申请号：US828496
申请日：1986-02-11
申请人： Fred E. Silverstein , Roy W. Martin , David A. Gilbert
发明人： Fred E. Silverstein , Roy W. Martin , David A. Gilbert
IPC分类号： A61B1/012 , A61B1/015 , A61B1/018 , A61B1/273 , A61B8/06 , A61B8/12 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/14 , A61B10/00
CPC分类号： A61B17/22 , A61B1/00177 , A61B1/018 , A61B1/2736 , A61B8/06 , A61B8/12 , A61B8/445 , A61B17/3478 , A61B2017/320084 , A61B2018/1407 , A61B5/489
摘要： A system for endoscopic detection of blood flow is disclosed. A catheter is sized to pass through the biopsy channel of an endoscope and includes an elongated catheter tube of flexible material and an ultrasonic probe carried by the catheter tube adjacent its tip. Depending on the application, the ultrasonic field provided by the ultrasonic probe may be either transverse or parallel to the longitudinal axis of the catheter tube and may be either highly directional, omnidirectional, or sectorial. The ultrasonic probe is coupled to a pulsed Doppler circuit (FIG. 16) by an isolation circuit (FIG. 20) that provides electrical isolation and RFI suppression. The Doppler circuit is designed to enhance close proximity detection of blood flow, to limit the range of the probe's ultrasonic field, and to distinguish between arterial blood flow, venous blood flow, and vessel wall motion.
摘要翻译：公开了一种内窥镜检测血流的系统。导管的尺寸设置成穿过内窥镜的活检通道，并且包括柔性材料的细长导管和由导管邻近其尖端承载的超声波探头。根据应用，由超声波探头提供的超声波场可以是横向的或平行于导管的纵向轴线，并且可以是高度定向的，全向的或扇形的。超声波探头通过提供电隔离和RFI抑制的隔离电路（图20）耦合到脉冲多普勒电路（图16）。多普勒电路设计用于增强血流的近距离检测，限制探头的超声波场的范围，并区分动脉血流，静脉血流和血管壁运动。

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