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1. 发明授权

US07689290B2 Devices, methods, and systems for shrinking tissues 有权
标题翻译：用于收缩组织的装置，方法和系统
公开(公告)号：US07689290B2
公开(公告)日：2010-03-30
申请号：US10866052
申请日：2004-06-10
申请人： Frank W. Ingle , Garry L. Carter , Michael D. Laufer
发明人： Frank W. Ingle , Garry L. Carter , Michael D. Laufer
IPC分类号： A61F2/00
CPC分类号： A61N1/403 , A61B18/14 , A61B18/1477 , A61B18/1482 , A61B18/1492 , A61B2018/00083 , A61B2018/00095 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00505 , A61B2018/00517 , A61B2018/00523 , A61B2018/00553 , A61B2018/00559 , A61B2018/00898 , A61B2018/126 , A61B2018/1425 , A61B2018/1467 , A61N1/06
摘要： Devices, systems, and method for treating urinary incontinence generally relying on energy delivered to a patient's pelvic support tissue to selectively contract or shrink at least a portion of that pelvic support tissue so as to reposition the bladder. The energy will preferably be applied to the endopelvic fascia and/or an arcus tendineus fascia pelvis. A variety of devices and methods are provided for applying gentle resistive heating of these and other tissues to cause them to contract without imposing significant injury on the surrounding tissue structures. By applying sufficient energy over a predetermined time, the tissue can be raised to a temperature which results in contraction without significant necrosis or other tissue damage. By selectively contracting the support tissues, the bladder neck, sphincter, and other components of the urinary tract responsible for the control of urinary flow can be reconfigured or supported in a manner which reduces urinary leakage.
摘要翻译：用于治疗尿失禁的装置，系统和方法通常依赖于递送至患者的骨盆支撑组织的能量以选择性地收缩或收缩该盆腔支撑组织的至少一部分，以便重新定位膀胱。能量将优选地应用于内耳筋膜和/或腱骨筋膜骨盆。提供了各种装置和方法来施加这些和其他组织的温和电阻加热，以使它们收缩而不对周围组织结构造成重大伤害。通过在预定时间内施加足够的能量，组织可以升高到导致收缩而不显着坏死或其他组织损伤的温度。通过选择性地收缩支撑组织，可以以减少尿液泄漏的方式重新配置或支撑膀胱颈，括约肌和负责控制尿流的尿道的其他成分。

2. 发明授权

US07167757B2 Energy induced bulking and buttressing of tissue for incontinence 有权
标题翻译：能量引起的膨胀和组织尿失禁的支撑
公开(公告)号：US07167757B2
公开(公告)日：2007-01-23
申请号：US10827887
申请日：2004-04-19
申请人： Frank W. Ingle , Garry L. Carter , Michael D. Laufer
发明人： Frank W. Ingle , Garry L. Carter , Michael D. Laufer
IPC分类号： A61F7/12
CPC分类号： A61N1/403 , A61B18/14 , A61B18/1477 , A61B18/1482 , A61B18/1492 , A61B2018/00083 , A61B2018/00095 , A61B2018/00148 , A61B2018/00214 , A61B2018/00232 , A61B2018/00505 , A61B2018/00517 , A61B2018/00523 , A61B2018/00553 , A61B2018/00559 , A61B2018/00898 , A61B2018/126 , A61B2018/1425 , A61B2018/1467 , A61N1/06
摘要： Devices, systems, and method for treating urinary incontinence generally rely on energy delivered to a patient's own pelvic support tissue to selectively contract or shrink at least a portion of that pelvic support tissue so as to reposition the bladder. Devices and methods apply gentle resistive heating of tissues to cause them to contract without imposing significant injury on the surrounding tissue structures. Alternative heat-applying probes heat tissue structures which comprise or support a patient's urethra. By selectively contracting the support tissues, the bladder neck, sphincter, and other components of the urinary tract responsible for the control of urinary flow can be reconfigured or supported in a manner which reduces urinary leakage.
摘要翻译：用于治疗尿失禁的装置，系统和方法通常依赖于输送到患者自身的骨盆支撑组织的能量来选择性地收缩或收缩该盆腔支撑组织的至少一部分，以便重新定位膀胱。装置和方法应用组织的温和电阻加热使它们收缩而不对周围组织结构造成重大伤害。替代的热应用探针加热构成或支持患者尿道的组织结构。通过选择性地收缩支撑组织，可以以减少尿液泄漏的方式重新配置或支撑膀胱颈，括约肌和负责控制尿流的尿道的其他成分。

3. 发明授权

US06546934B1 Noninvasive devices and methods for shrinking of tissues 有权
标题翻译：非侵入性装置和组织收缩方法
公开(公告)号：US06546934B1
公开(公告)日：2003-04-15
申请号：US09651435
申请日：2000-08-30
申请人： Frank Ingle , Garry L. Carter , Robert J. Laird , Paul Do , Brian J. Mosel , Michael D. Laufer , Loren L. Roy
发明人： Frank Ingle , Garry L. Carter , Robert J. Laird , Paul Do , Brian J. Mosel , Michael D. Laufer , Loren L. Roy
IPC分类号： A61B1900
CPC分类号： A61B18/1482 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B18/1815 , A61B2017/00084 , A61B2017/003 , A61B2018/00011 , A61B2018/00023 , A61B2018/00083 , A61B2018/00095 , A61B2018/00148 , A61B2018/0016 , A61B2018/0022 , A61B2018/00232 , A61B2018/00505 , A61B2018/00517 , A61B2018/00523 , A61B2018/00553 , A61B2018/00559 , A61B2018/00791 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/1425 , A61B2018/1467 , A61B2018/1472 , A61B2090/3782 , A61B2218/002 , A61N1/06 , A61N1/403 , A61N7/02
摘要： The invention provides improved devices, methods, and systems for shrinking of collagenated tissues, particularly for treating urinary incontinence in a noninvasive manner by directing energy to a patient's own support tissues. The energy can be applied intermittently, often between a pair of large plate electrodes having cooled flat electrode surfaces, the electrodes optionally being supported by a clamp structure. Such cooled plate electrodes are capable of directing electrical energy through an intermediate tissue and into fascia while the cooled electrode surface prevents injury to the intermediate tissue, particularly where the electrode surfaces are cooled before, during, and after an intermittent heating cycle.
摘要翻译：本发明提供了用于收缩胶原组织的改进的装置，方法和系统，特别是通过将能量引导到患者自己的支撑组织以非侵入性方式治疗尿失禁。间歇地施加能量，通常在具有冷却的平坦电极表面的一对大平板电极之间，电极可选地由夹持结构支撑。这样的冷却板电极能够将电能引导通过中间组织并进入筋膜，同时冷却的电极表面防止对中间组织的损伤，特别是在电极表面在间歇加热循环之前，期间和之后被冷却时。

4. 发明授权

US10987164B2 Methods and devices for diastolic assist 有权
公开(公告)号：US10987164B2
公开(公告)日：2021-04-27
申请号：US16185402
申请日：2018-11-09
申请人： Michael D. Laufer , Freddy Abnousi
发明人： Michael D. Laufer , Freddy Abnousi
IPC分类号： A61B18/14 , A61M1/10 , A61M1/12 , A61B17/3209 , A61B18/20 , A61B17/00 , A61B17/32 , A61B17/30 , A61B18/00
摘要： The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff. For example, improving a diastolic heart function in a heart by creating at least one incision in cardiac muscle forming an interior heart wall of the interior chamber where the at least one incision extends into one or more layers of the interior heart wall without puncturing through the interior heart wall and the incision is sufficient to reduce a stiffness of the interior chamber to increase volume of the chamber and reduce diastolic filling pressure.

5. 发明授权

US10154879B2 Methods and devices for diastolic assist 有权
公开(公告)号：US10154879B2
公开(公告)日：2018-12-18
申请号：US15719347
申请日：2017-09-28
申请人： Michael D. Laufer , Freddy Abnousi
发明人： Michael D. Laufer , Freddy Abnousi
IPC分类号： A61N1/362 , A61B18/14 , A61M1/10 , A61B17/3209 , A61M1/12 , A61B18/20 , A61B17/00 , A61B17/32 , A61B17/30 , A61B18/00
摘要： The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff. For example, improving a diastolic heart function in a heart by creating at least one incision in cardiac muscle forming an interior heart wall of the interior chamber where the at least one incision extends into one or more layers of the interior heart wall without puncturing through the interior heart wall and the incision is sufficient to reduce a stiffness of the interior chamber to increase volume of the chamber and reduce diastolic filing pressure.

6. 发明授权

US09211154B2 Methods and devices for removing omental tissue 有权
标题翻译：用于去除网膜组织的方法和装置
公开(公告)号：US09211154B2
公开(公告)日：2015-12-15
申请号：US13098224
申请日：2011-04-29
申请人： Michael D. Laufer
发明人： Michael D. Laufer
IPC分类号： A61B18/08 , A61B18/14 , A61B17/30 , A61B17/3205 , A61B17/32
CPC分类号： A61B18/14 , A61B17/30 , A61B17/32056 , A61B18/1482 , A61B18/1492 , A61B2017/306 , A61B2017/320044 , A61B2018/141
摘要： The invention relates to a method of treating obesity, insulin resistance and co-morbidities of these conditions by removing tissue from the abdomen. More specifically, it relates to a method of removing abdominal fat and omentum to which the fat is attached, in order to improve health. The invention includes a device for safely removing this tissue material
摘要翻译：本发明涉及通过从腹部去除组织来治疗肥胖症，胰岛素抵抗和这些病症的并发症的方法。更具体地说，本发明涉及一种去除脂肪附着的腹部脂肪和网膜的方法，以改善健康。本发明包括用于安全地去除该组织材料的装置

7. 发明授权

US08870821B2 Device for tissue injection 有权
标题翻译：组织注射装置
公开(公告)号：US08870821B2
公开(公告)日：2014-10-28
申请号：US11549454
申请日：2006-10-13
申请人： Michael D. Laufer
发明人： Michael D. Laufer
IPC分类号： A61M37/00
CPC分类号： A61M37/00
摘要： A system for administering an injection is described. The invention consists of an adhesive patch with an integrated injector that controllably insets an injection needle and delivers the medication contained within the patch. Variations of the system may also subsequently and automatically retracts the needle, rendering the patch safely inert. In additional variations, a portion of the system may remain on the patient and function as a bandage.
摘要翻译：描述了用于施用注射的系统。本发明包括具有集成注射器的粘合贴片，其可控制地插入注射针并递送包含在贴片内的药物。系统的变化也可以随后并且自动缩回针，使贴片安全地惰性。在另外的变型中，系统的一部分可以保留在患者身上并用作绷带。

8. 发明授权

US08521295B2 Location and deactivation of muscles 失效
标题翻译：肌肉的位置和停用
公开(公告)号：US08521295B2
公开(公告)日：2013-08-27
申请号：US11743121
申请日：2007-05-01
申请人： Michael D. Laufer
发明人： Michael D. Laufer
IPC分类号： A61N1/18
CPC分类号： A61B5/04001 , A61B5/4041 , A61B5/4893 , A61B18/14 , A61B2018/00434 , A61N1/0551 , A61N1/328 , A61N7/02
摘要： Methods and devices for treatment to at least interfere with the function of a muscle are described herein. These methods and devices may have application in cosmetic and plastic surgery, dermatology, suppression of tension and/or migraine-type headaches, pain management, one particular application of the subject matter deals primarily with reducing wrinkles caused by ongoing muscular activation. The devices and methods described herein allow medical practitioners to effectively identify selective nerves for paralyzingmuscles, without the need for injections of agents such as botulism toxin. Moreover, the devices and methods herein, may allow for artificial generation of signals in nerves that were otherwise damaged by stimulating transmission of nerve signals across damaged nerves.
摘要翻译：本文描述了至少干扰肌肉功能的治疗方法和装置。这些方法和装置可以应用于化妆和整形手术，皮肤病学，抑制紧张和/或偏头痛型头痛，疼痛管理，主题的一个特定应用主要涉及减少正在进行的肌肉活化引起的皱纹。本文描述的装置和方法允许医疗人员有效地识别麻痹肌肉的选择性神经，而不需要注射诸如肉毒杆菌毒素的药剂。此外，这里的装置和方法可以允许神经中的信号的人工产生，否则通过刺激神经信号穿过受损神经的传播而被损坏。

9. 发明授权

US08161978B2 Methods for treating asthma by damaging nerve tissue 有权
标题翻译：通过损伤神经组织治疗哮喘的方法
公开(公告)号：US08161978B2
公开(公告)日：2012-04-24
申请号：US12727156
申请日：2010-03-18
申请人： Christopher J. Danek , Bryan E. Loomas , Thomas M. Keast , Michael D. Laufer
发明人： Christopher J. Danek , Bryan E. Loomas , Thomas M. Keast , Michael D. Laufer
IPC分类号： A61B19/00 , A61F7/00
CPC分类号： A61B18/02 , A61B18/04 , A61B18/08 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00434 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/0212 , A61B2090/3614 , A61F7/123 , A61F2007/0018 , A61F2007/0059 , A61F2007/126 , A61M25/0043 , A61M29/00 , A61M29/02 , A61M2025/0096 , A61M2210/1039 , A61N1/06 , A61N1/403 , A61N5/00
摘要： A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要翻译：在可逆性慢性阻塞性肺疾病如哮喘发作的急性发作期间治疗肺的方法。该方法包括将能量传递到气道的气道壁，使得气道的直径增加。在哮喘发作之前，期间或之后，能量可能转移到气道壁。能量可以以足以临时或永久地增加气道直径的量来转移。该方法可以在气道打开，关闭或部分关闭时进行。

10. 发明申请

US20110282229A1 METHODS OF EVALUATING INDIVIDUALS HAVING REVERSIBLE OBSTRUCTIVE PULMONARY DISEASE 有权
标题翻译：评估具有可逆性阻塞性肺疾病的个体的方法
公开(公告)号：US20110282229A1
公开(公告)日：2011-11-17
申请号：US13171345
申请日：2011-06-28
申请人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly M. Shriner , William J. Wizeman
发明人： Christopher James Danek , Michael Biggs , Bryan Loomas , Michael D. Laufer , Gary Kaplan , Kelly M. Shriner , William J. Wizeman
IPC分类号： A61B5/087 , A61B5/091 , A61B5/08
CPC分类号： A61B18/00 , A61B17/22004 , A61B18/08 , A61B18/14 , A61B18/1492 , A61B2017/00115 , A61B2017/00292 , A61B2017/003 , A61B2017/22062 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00541 , A61B2018/00654 , A61B2018/00666 , A61B2018/00678 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00803 , A61B2018/044 , A61B2018/046 , A61B2018/1807 , A61B2090/3614 , A61M25/0043 , A61M29/00 , A61M2025/0096 , A61M2210/1039 , A61N5/0601
摘要： This relates to treating an asthmatic lung and more particularly, relates to advancing a treatment device into the lung and treating the lung with the device. This also includes additional steps of treating the airway wall, applying energy or heat to the airway wall in an asthmatic lung.
摘要翻译：这涉及治疗哮喘肺，更具体地涉及将治疗装置推进到肺中并用装置治疗肺。这还包括治疗气道壁，向哮喘肺中的气道壁施加能量或热量的附加步骤。

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