专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5939466A Poly-unsaturated carbohydrate derivatives, polymers thereof and their use 失效
标题翻译：多不饱和碳水化合物衍生物及其用途及其用途
公开(公告)号：US5939466A
公开(公告)日：1999-08-17
申请号：US817044
申请日：1997-04-04
申请人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
发明人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
IPC分类号： G02C7/04 , A61K9/00 , A61K47/36 , C07D493/04 , C07H13/12 , C07H15/04 , C08B37/00 , C08B37/16 , C08F12/00 , C08F18/00 , C08F20/36 , C08F220/36 , G02B1/04 , G02B1/10 , C07H15/02 , C07H265/04
CPC分类号： C07D493/04 , C07H13/12 , C07H15/04 , C08B37/0012 , C08F220/36 , G02B1/043
摘要： The present invention relates to polymerizable derivatives of carbohydrates comprising a carbohydrate radical and more than one radically polymerizable hydrocarbon group which is linked optionally via a spacer to the carbohydrate radical, to homopolymers, copolymers, block copolymers, graft copolymers and polymeric networks thereof, to capsules, fibers, films and coatings having water-binding and biocompatible properties, and to molded articles, for example contact lenses or biomedicinal articles, comprising the mentioned polymers, as well as to processes for the preparation of the mentioned polymers and articles.
摘要翻译： PCT No.PCT / EP95 / 04052 Sec。 371日期1997年04月4日 102（e）日期1997年4月4日PCT提交1995年10月16日PCT公布。第WO96 / 13511号公报日期1996年5月9日本发明涉及碳水化合物的可聚合衍生物，其包含碳水化合物基团和多于一个可自由基聚合的烃基，其任选经由间隔基连接至碳水化合物基团，至均聚物，共聚物，嵌段共聚物，接枝共聚物和聚合物网络具有水结合和生物相容性质的胶囊，纤维，膜和涂层，以及包含所述聚合物的模制品，例如隐形眼镜或生物医学制品，以及制备所述聚合物和制品的方法。

2. 发明授权

US5693768A Unsaturated carbohydrate derivatives polymers thereof and their use 失效
标题翻译：不饱和碳水化合物衍生物的聚合物及其用途
公开(公告)号：US5693768A
公开(公告)日：1997-12-02
申请号：US388006
申请日：1995-02-13
申请人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
发明人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
IPC分类号： G02C7/04 , A61L27/34 , C07H13/12 , C07H15/04 , C08B37/16 , C08F20/36 , C08F290/00 , C08F290/06 , G02B1/04 , C07H15/10 , C07H15/12
CPC分类号： C07H13/12 , A61L27/34 , C07H15/04 , C08B37/0012 , C08F20/36 , G02B1/043
摘要： The present invention relates to polymerisable derivatives of carbohydrates comprising a compound of formula (I) R.sup.1 --(COO--Alk).sub.m -(OCONH--R).sub.n -(NHCO).sub.p Y--Z (I) wherein R.sup.1 is a radically polymerisable hydrocarbon group; m, n and p are 0 or 1; Alk is alkylene having up to 10 carbon atoms; R is a diradical, having up to 20 carbon atoms, of an organic diisocyanate; Z is a monovalent radical, minus a single hydroxy group, of a mono-, di- or tri-saccharide, of an oligosaccharide, of a cyclodextrin (CD) or of an anhydrosaccharide; and Y is --O-- or --NH--; with the proviso that when p is zero, m and n are also zero and Y is --NH--; to homopolymers, copolymers, block copolymers, graft copolymers and polymeric networks thereof, to moulded articles, for example contact lenses or biomedicinal articles, comprising the mentioned polymers, as well as to processes for the preparation of the mentioned polymers and articles.
摘要翻译：本发明涉及碳水化合物的可聚合衍生物，其包含式（I）化合物R1-（COO-Alk）m-（OCONH-R）n-（NHCO）pY-Z（I）的化合物，其中R1是可自由基聚合的烃基 ; m，n和p为0或1; Alk是具有至多10个碳原子的亚烷基; R是具有至多20个碳原子的双键，有机二异氰酸酯; Z是低聚糖，环糊精（CD）或非水解糖的单糖，二糖或三糖的单一基团，减去单个羟基; Y为-O-或-NH-; 条件是当p为0时，m和n也为零，Y为-NH-; 至均聚物，共聚物，嵌段共聚物，接枝共聚物和聚合物网络，包括所述聚合物的模塑制品，例如隐形眼镜或生物医学制品，以及制备所述聚合物和制品的方法。

3. 发明授权

US5856416A Unsaturated carbohydrate derivatives polymers thereof and their use 失效
标题翻译：不饱和碳水化合物衍生物的聚合物及其用途
公开(公告)号：US5856416A
公开(公告)日：1999-01-05
申请号：US867747
申请日：1997-06-03
申请人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
发明人： Frank Bachmann , Dieter Lohmann , Peter Chabrecek
IPC分类号： G02C7/04 , A61L27/34 , C07H13/12 , C07H15/04 , C08B37/16 , C08F20/36 , C08F290/00 , C08F290/06 , G02B1/04 , C08F220/04
CPC分类号： C07H13/12 , A61L27/34 , C07H15/04 , C08B37/0012 , C08F20/36 , G02B1/043
摘要： The present invention relates to polymerizable derivatives of carbohydrates comprising a compound of formula (I)R.sup.1 --(COO--Alk).sub.m --(OCONH--R).sub.n --(NHCO).sub.p --Y--Z (I)whereinR.sup.1 is a radically polymerizable hydrocarbon group;m, n and p are 0 or 1;Alk is alkylene having up to 10 carbon atoms;R is a diradical, having up to 20 carbon atoms, of an organic diisocyanate;Z is a monovalent radical, minus a single hydroxy group, of a mono-, di- or tri-saccharide, of an oligosaccharide, of a cyclodextrin (CD) or of an anhydrosaccharide; andY is --O-- or --NH--;with the proviso that when p is zero, m and n are also zero and Y is --NH--; to homopolymers, copolymers, block copolymers, graft copolymers and polymeric networks thereof, to molded articles, for example contact lenses or biomedicinal articles, comprising the mentioned polymers, as well as to processes for the preparation of the mentioned polymers and articles.
摘要翻译：本发明涉及碳水化合物的可聚合衍生物，其包含式（I）化合物R1-（COO-Alk）m-（OCONH-R）n-（NHCO）p-Y-Z（I）的化合物，其中R1是可自由基聚合的烃基; m，n和p为0或1; Alk是具有至多10个碳原子的亚烷基; R是具有至多20个碳原子的双键，有机二异氰酸酯; Z是低聚糖，环糊精（CD）或非水解糖的单糖，二糖或三糖的单一基团，减去单个羟基; Y为-O-或-NH-; 条件是当p为0时，m和n也为零，Y为-NH-; 至均聚物，共聚物，嵌段共聚物，接枝共聚物和聚合物网络，包括所述聚合物的模塑制品，例如隐形眼镜或生物医学制品，以及制备所述聚合物和制品的方法。

4. 发明授权

US07538146B2 Extended wear ophthalmic lens 失效
公开(公告)号：US07538146B2
公开(公告)日：2009-05-26
申请号：US11618800
申请日：2006-12-30
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： C08F290/06
CPC分类号： G02B1/043 , A61L27/26 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , C08L43/04 , C08L75/04 , C08L51/085 , C08L2666/20 , C08L51/08 , C08L83/04 , C08L33/00 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

5. 发明授权

US07468398B2 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US07468398B2
公开(公告)日：2008-12-23
申请号：US11146586
申请日：2005-06-07
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorg Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorg Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： C08F290/06
CPC分类号： G02B1/043 , A61L27/26 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , C08L43/04 , C08L75/04 , C08L51/085 , C08L2666/20 , C08L51/08 , C08L83/04 , C08L33/00 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
摘要翻译：一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有实质的佩戴者不适。透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。优选的透镜是含氧大分子单体和离子单体单体的共聚产物。本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

6. 发明授权

US06951894B1 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US06951894B1
公开(公告)日：2005-10-04
申请号：US09640526
申请日：2000-08-17
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jörg Griesser , Arthur Ho , Jens Höpken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jürgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jörg Griesser , Arthur Ho , Jens Höpken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jürgen Vogt , Lynn Cook Winterton
IPC分类号： G02C7/04 , A61F20060101 , A61F2/14 , A61L27/00 , A61L27/26 , A61L27/34 , B05D7/24 , B29C39/42 , B29C71/00 , B29D11/00 , C08F220/22 , C08F290/06 , C08F290/14 , C08F299/08 , C08G20060101 , C08G18/10 , C08G18/48 , C08G18/50 , C08G18/61 , C08G18/67 , C08G18/81 , C08G18/83 , C08G77/00 , C08G77/04 , C08G77/46 , C08J5/00 , C08K3/00 , C08L20060101 , C08L33/08 , C08L33/10 , C08L83/04 , G02B1/04 , G02C20060101
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
摘要翻译：一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有很大的佩戴者不适。透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。优选的透镜是含氧大分子单体和离子单体单体的共聚产物。本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

7. 发明授权

US06730366B2 Process for modifying a surface 有权
标题翻译：改变表面的工艺
公开(公告)号：US06730366B2
公开(公告)日：2004-05-04
申请号：US10056168
申请日：2002-01-24
申请人： Dieter Lohmann , Peter Chabrecek , Jörg Leukel
发明人： Dieter Lohmann , Peter Chabrecek , Jörg Leukel
IPC分类号： C23C1428
CPC分类号： C08J7/047 , Y10T428/31504 , Y10T428/31623
摘要： The invention relates to a process for coating a material surface comprising the steps of: (a) applying to the material surface one or more different comb-type polymers comprising a polymer backbone and side chains pendently attached thereto, wherein at least a part of the side chains carry a triggerable precursor for carbene or nitrene formation; and (b) fixing the polymer(s) onto the material surface using heat or radiation, in particular radiation such as UV or visible light. The polymers of the invention are useful for the modification of material surfaces and are particularly suitable for providing biomedical articles such as contact lenses with a hydrophilic coating.
摘要翻译：本发明涉及一种用于涂覆材料表面的方法，包括以下步骤：（a）向材料表面施加一种或多种不同的梳型聚合物，其包含聚合物主链和侧链附着于其上，其中至少一部分侧链携带可触发的卡宾或者氮烯形成前体; 和（b）使用热或辐射，特别是诸如UV或可见光的辐射将聚合物固定在材料表面上。本发明的聚合物可用于改性材料表面，并且特别适用于提供生物医学制品例如具有亲水涂层的隐形眼镜。

8. 发明授权

US5612391A Functionalized photoinitiators, macromers thereof, and the use thereof for contact lens 失效
标题翻译：官能化光引发剂，其大分子单体及其用于隐形眼镜的用途
公开(公告)号：US5612391A
公开(公告)日：1997-03-18
申请号：US469399
申请日：1995-06-06
申请人： Peter Chabrecek , Dieter Lohmann
发明人： Peter Chabrecek , Dieter Lohmann
IPC分类号： G02C7/04 , C07C49/76 , C07C49/82 , C07C271/20 , C07C271/24 , C07C271/28 , C07C271/32 , C07C271/38 , C07D317/26 , C07F7/10 , C08B31/00 , C08B33/00 , C08B37/00 , C08B37/08 , C08B37/16 , C08F2/48 , C08F2/50 , C08F8/30 , C08F16/36 , C08G18/00 , C08G18/08 , C08G18/71 , C08G77/04 , C08G77/38 , C08J3/28 , C08J7/12 , C08J7/18 , C08L101/02 , G02B1/04 , G03F7/031 , G03F7/075 , C08J5/00 , C08J5/18 , C08J7/04
CPC分类号： G03F7/075 , C07C271/20 , C07C271/24 , C07C271/28 , C07C271/38 , C08B37/0012 , C08B37/0072 , C08F2/50 , C08F8/30 , C08G77/38 , C08J7/12 , C08J7/18 , G02B1/043 , G03F7/031 , C07C2101/14 , Y10S522/904 , Y10S522/905 , Y10T428/31645 , Y10T428/31663 , Y10T428/31667 , Y10T428/31855 , Y10T428/31971
摘要： Contact lenses formed from compounds of formula I: ##STR1## are disclosed. The compounds are photoinitiators which can be functionalized by means of ethylenic groups or can be bonded to H-active substances, in order, for example, to modify surfaces by means of photopolymerizable substances. The compounds are especially useful in the manufacture of contact lenses.
摘要翻译：公开了由式I化合物形成的隐形眼镜：。这些化合物是可以通过烯属基官能化或可以与H-活性物质结合的光引发剂，以便例如通过可光聚合物质来修饰表面。这些化合物在隐形眼镜的制造中特别有用。

9. 发明授权

US08568626B2 Extended wear ophthalmic lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US08568626B2
公开(公告)日：2013-10-29
申请号：US12252406
申请日：2008-10-16
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorge Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, Jr. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： B29D11/00
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionoperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.
摘要翻译：提供了制备硅酮水凝胶隐形眼镜的方法。在一个实施方案中，预聚物混合物在具有小于约10000ppm氧气的气氛中在透镜模具中聚合以形成适于延长磨损的硅氧烷水凝胶隐形眼镜，其特征在于连续磨损一段时间后产生小于10％的角膜溶胀包括正常睡眠期为7天。在一个实施方案中，预聚物混合物包含至少一种含有亲水基团的含氧物质，其中所述至少一种含氧物质是含硅氧烷的大分子单体或至少一种离子交换材料和交联剂。在某些实施方案中，预聚物混合物的聚合可以在具有小于约1000ppm氧气的气氛中进行。

10. 发明申请

US20090039535A1 Extended Wear Ophthalmic Lens 失效
标题翻译：延长佩戴眼科镜片
公开(公告)号：US20090039535A1
公开(公告)日：2009-02-12
申请号：US12252406
申请日：2008-10-16
申请人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorg Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, JR. , Jurgen Vogt , Lynn Cook Winterton
发明人： Paul Clement Nicolson , Richard Carlton Baron , Peter Chabrecek , John Court , Angelika Domschke , Hans Jorg Griesser , Arthur Ho , Jens Hopken , Bronwyn Glenice Laycock , Qin Liu , Dieter Lohmann , Gordon Francis Meijs , Eric Papaspiliotopoulos , Judy Smith Riffle , Klaus Schindhelm , Deborah Sweeney , Wilson Leonard Terry, JR. , Jurgen Vogt , Lynn Cook Winterton
IPC分类号： B29D11/00
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.
摘要翻译：提供了制备硅酮水凝胶隐形眼镜的方法。在一个实施方案中，预聚物混合物在具有小于约ppm氧气的气氛中在透镜模具中聚合以形成适于延长磨损的硅氧烷水凝胶隐形眼镜，其特征在于在连续磨损一段时间后产生小于10％的角膜溶胀包括正常睡眠期的7天。在一个实施方案中，预聚物混合物包含至少一种含有亲水基团的含氧物质，其中所述至少一种含氧物质是含硅氧烷的大分子单体或单体，至少一种离子精子材料和交联剂。在某些实施方案中，预聚物混合物的聚合可以在具有小于约1000ppm氧气的气氛中进行。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式