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1. 发明申请

US20060293332A1 Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists 失效
公开(公告)号：US20060293332A1
公开(公告)日：2006-12-28
申请号：US11429656
申请日：2006-05-05
申请人： Francine Grant , Sarah Bartulis , Louis Brogley , Michael Dappen , Ramesh Kasar , Mohammed Khan , Martin Neitzel , Michael Pleiss , Eugene Thorsett , John Tucker , Michael Ye , Jon Hawkinson
发明人： Francine Grant , Sarah Bartulis , Louis Brogley , Michael Dappen , Ramesh Kasar , Mohammed Khan , Martin Neitzel , Michael Pleiss , Eugene Thorsett , John Tucker , Michael Ye , Jon Hawkinson
IPC分类号： A61K31/498 , C07D241/36
CPC分类号： C07D401/14 , C07D241/44 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Disclosed are sulfonylquinoxalone acetamide derivatives useful as bradykinin antagonists.

2. 发明授权

US07635775B2 Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists 失效
标题翻译：磺酰喹诺酮衍生物和相关化合物作为缓激肽拮抗剂
公开(公告)号：US07635775B2
公开(公告)日：2009-12-22
申请号：US11429656
申请日：2006-05-05
申请人： Francine S. Grant , Sarah Bartulis , Louis Brogley , Michael S. Dappen , Ramesh Kasar , Mohammed A. Khan , Martin Neitzel , Michael A. Pleiss , Eugene D. Thorsett , John Tucker , Michael Ye , Jon E. Hawkinson
发明人： Francine S. Grant , Sarah Bartulis , Louis Brogley , Michael S. Dappen , Ramesh Kasar , Mohammed A. Khan , Martin Neitzel , Michael A. Pleiss , Eugene D. Thorsett , John Tucker , Michael Ye , Jon E. Hawkinson
IPC分类号： A61K31/498 , C07D241/50 , A61P11/06 , A61P25/06 , A61P25/02
CPC分类号： C07D401/14 , C07D241/44 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Disclosed are sulfonylquinoxalone acetamide derivatives useful as bradykinin antagonists.
摘要翻译：公开了用作缓激肽拮抗剂的磺酰基喹喔啉乙酰胺衍生物。

3. 发明授权

US07183281B2 Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists 失效
标题翻译：磺酰喹诺酮衍生物和相关化合物作为缓激肽拮抗剂
公开(公告)号：US07183281B2
公开(公告)日：2007-02-27
申请号：US10429917
申请日：2003-05-02
申请人： Francine S. Grant , Sarah Bartulis , Louis Brogley , Michael S. Dappen , Ramesh Kasar , Mohammed A. Khan , Martin Neitzel , Michael A. Pleiss , Eugene D. Thorsett , John Tucker , Michael Ye , Jon E. Hawkinson
发明人： Francine S. Grant , Sarah Bartulis , Louis Brogley , Michael S. Dappen , Ramesh Kasar , Mohammed A. Khan , Martin Neitzel , Michael A. Pleiss , Eugene D. Thorsett , John Tucker , Michael Ye , Jon E. Hawkinson
IPC分类号： A01N43/58 , A01N43/60 , A61K31/50 , A61K31/495 , C07D413/00
CPC分类号： C07D401/14 , C07D241/44 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Disclosed are sulfonylquinoxalone derivatives of the general formula: These compounds are useful as bradykinin antagonists.
摘要翻译：公开了以下通式的磺酰基喹诺酮衍生物：这些化合物可用作缓激肽拮抗剂。

4. 发明授权

US07056937B2 Sulfonylquinoxalone derivatives as bradykinin antagonists 失效
标题翻译：磺酰喹诺酮衍生物作为缓激肽拮抗剂
公开(公告)号：US07056937B2
公开(公告)日：2006-06-06
申请号：US10429203
申请日：2003-05-02
申请人： Francine S. Grant , Sarah Bartulis , Louis Brogley , Michael S. Dappen , Ramesh Kasar , Ryan Holcomb , Michael A. Pleiss , Eugene D. Thorsett , Michael Ye , Jon E. Hawkinson
发明人： Francine S. Grant , Sarah Bartulis , Louis Brogley , Michael S. Dappen , Ramesh Kasar , Ryan Holcomb , Michael A. Pleiss , Eugene D. Thorsett , Michael Ye , Jon E. Hawkinson
IPC分类号： A01N43/40 , A61K31/44 , C07D239/00 , C07D239/70 , C07D47/00
CPC分类号： C07D401/14 , C07D241/44 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Disclosed are 1-sulfonylquioxalone acetamides and derivatives thereof. The compounds are exemplified by compounds of the formula: Such compounds, derivatives and related compounds are useful as bradykinin antagonists.
摘要翻译：公开了1-磺酰基二氧杂环己烷乙酰胺及其衍生物。化合物的实例是下式的化合物：这样的化合物，衍生物和相关化合物可用作缓激肽拮抗剂。

5. 发明申请

US20120266956A1 MOUNTING ASSEMBLY FOR A SOLAR PANEL AND METHOD FOR MOUNTING THEREOF 审中-公开
标题翻译：一种太阳能面板的安装组件及其安装方法
公开(公告)号：US20120266956A1
公开(公告)日：2012-10-25
申请号：US13377336
申请日：2011-04-12
申请人： Michael Ye , Kaileung Fan
发明人： Michael Ye , Kaileung Fan
IPC分类号： H01L31/0203 , B23P11/00
CPC分类号： H02S20/00 , F24S25/30 , F24S25/613 , F24S25/632 , Y02E10/47 , Y02E10/50 , Y10T29/49966
摘要： A mounting assembly (1) for a solar panel, comprising beams (10), pressing blocks (30) and a plurality of anti-slip blocks (40), said beams (10) are paralleled and transversely fixed to installation part outdoors, and the upper portion of said beam (10) is provided with a long groove (101) along the longitudinal direction of the beam, and the opposing side walls of said long groove (101) extended to said groove (101) to form a supporting portion (102), one end of said anti-slip block (30) is slidably inserted into said long groove (101), the other end of said anti-slip block (30) is loaded on said supporting portion (102) and is fixed to the back of said solar panel, and said pressing block (20) is pushed and pressed on the side edge of said solar panel and is fixed to said beam (10). The installation of solar panel can be realized by inserting the anti-slip block (30) in the back of solar panel into the long groove (101) of beam (10), the operation is easy and can bring amazing stability; furthermore, spare of the setting of strengthened rib with great span disposed on the solar panel, only if the use of beam (10) and anti-slip block (40) with small volume, further simplifying the mounting structure and saving material, so as to reduce the cost of human source and material. Besides, a method for assembling solar panel is disclosed in the present invention.
摘要翻译：一种用于太阳能电池板的安装组件（1），包括梁（10），压块（30）和多个防滑块（40），所述梁（10）平行并横向固定到室外的安装部分，以及所述梁（10）的上部沿着梁的纵向方向设置有长槽（101），并且所述长槽（101）的相对的侧壁延伸到所述槽（101）以形成支撑部分（102），所述防滑块（30）的一端可滑动地插入所述长槽（101）中，所述防滑块（30）的另一端装载在所述支撑部分（102）上并固定到所述太阳能面板的背面，并且所述按压块（20）被推压并压在所述太阳能电池板的侧边缘上并固定到所述光束（10）。通过将太阳能电池板背面的防滑块（30）插入梁（10）的长槽（101）中，可以实现太阳能电池板的安装，操作容易，可以带来惊人的稳定性; 此外，只要使用体积小的梁（10）和防滑块（40），只需放置在太阳能电池板上的大跨度加强筋的设置，进一步简化安装结构并节省材料，以便降低人力资源和材料的成本。此外，在本发明中公开了一种用于组装太阳能电池板的方法。

6. 发明授权

US10928366B2 Compositions and methods for combining protein precipitation and solid phase extraction 有权
公开(公告)号：US10928366B2
公开(公告)日：2021-02-23
申请号：US12019445
申请日：2008-01-24
申请人： Craig Aurand , Charles Mi , Paul Ross , An Trinh , Hillel Brandes , Michael Ye
发明人： Craig Aurand , Charles Mi , Paul Ross , An Trinh , Hillel Brandes , Michael Ye
IPC分类号： G01N33/84 , G01N30/60 , B01J20/10 , B01J20/06 , B01J20/32 , G01N33/00
摘要： A composition, method and device for the preparation of biological samples for subsequent LC-MS analysis using a combined and concurrent protein precipitation and solid phase extraction (SPE) process is described. Through an integrated combination of protein precipitation, filtration, and SPE using a novel zirconia-coated chromatographic media, interfering compounds, such as proteins and phosphate-containing compounds, are eliminated from the biological samples, affording a higher degree of analyte response during LC-MS analysis.

7. 发明申请

US20120254710A1 RISK CHARTS FOR FAILURE MODE AND EFFECT ANALYSIS 审中-公开
标题翻译：不良模式和效果分析的风险
公开(公告)号：US20120254710A1
公开(公告)日：2012-10-04
申请号：US13435082
申请日：2012-03-30
申请人： Jason W. Flanagan , Jasmeen K. Harsh , Michael Ye
发明人： Jason W. Flanagan , Jasmeen K. Harsh , Michael Ye
IPC分类号： G06F17/20
CPC分类号： G06Q10/06395 , G06Q10/0631
摘要： A method to facilitate a failure modes and effects analysis (FMEA) project associated with one or more components or process during a product development cycle is provided. The method includes displaying on the user interface one or more information pages associated with sequential order of elements to be completed by one or more FMEA analysts. The method further involves receiving with an aid of the user interface textual inputs from the one or more FMEA analysts for the one or more information pages associated with the sequential orders of elements. The method further includes developing a risk chart for tracking a risk mitigation progress for the FMEA project associated with the one or more components or process during the product development cycle. The risk charts include a Criticality Matrix Risk Chart (CMRC) and a Pro-active Reliability Risk Chart (PRRC).
摘要翻译：提供了一种在产品开发周期中促进与一个或多个组件或过程相关的故障模式和效果分析（FMEA）项目的方法。该方法包括在用户界面上显示与一个或多个FMEA分析者要完成的元素的顺序顺序相关联的一个或多个信息页。该方法还涉及借助于用户界面来接收来自一个或多个FMEA分析者的文本输入，用于与元素的顺序顺序相关联的一个或多个信息页。该方法还包括开发一个风险图表，用于跟踪与产品开发周期内的一个或多个组件或过程相关联的FMEA项目的风险缓解进度。风险图表包括Criticality Matrix Risk Chart（CMRC）和Pro-Active Reliability Risk Chart（PRRC）。

8. 发明申请

US20120254044A1 GRAPHICAL USER INTERFACE FOR FAILURE MODE AND EFFECT ANALYSIS 审中-公开
标题翻译：用于故障模式和效果分析的图形用户界面
公开(公告)号：US20120254044A1
公开(公告)日：2012-10-04
申请号：US13435576
申请日：2012-03-30
申请人： Jason W. Flanagan , Jasmeen K. Harsh , Michael Ye
发明人： Jason W. Flanagan , Jasmeen K. Harsh , Michael Ye
IPC分类号： G06Q10/06
CPC分类号： G06Q10/06395 , G06Q10/0631
摘要： A method to facilitate a failure modes and effects analysis (FMEA) project associated with one or more components or process during a product development cycle is provided. A real time FMEA status is viewable through a user interface which indicates the progress of the FMEA project. The method includes displaying on the user interface one or more information pages associated with sequential order of elements to be completed by one or more FMEA analysts. The method further involves receiving with an aid of the user interface textual inputs from the one or more FMEA analysts for the one or more information pages associated with the sequential orders of elements. The method further includes representing, to the one or more FMEA analysts, the sequential order of elements in a tree structure format. The information associated with the sequential order of elements is editable and is updated in real time.
摘要翻译：提供了一种在产品开发周期中促进与一个或多个组件或过程相关的故障模式和效果分析（FMEA）项目的方法。通过用户界面可以看到实时FMEA状态，指示FMEA项目的进度。该方法包括在用户界面上显示与一个或多个FMEA分析者要完成的元素的顺序顺序相关联的一个或多个信息页。该方法还涉及借助于用户界面来接收来自一个或多个FMEA分析者的文本输入，用于与元素的顺序顺序相关联的一个或多个信息页。该方法还包括向一个或多个FMEA分析者表示树结构格式的元素的顺序。与元素的顺序相关联的信息是可编辑的并且被实时更新。

9. 发明申请

US20080213906A1 COMPOSITIONS AND METHODS FOR COMBINING PROTEIN PRECIPITATION AND SOLID PHASE EXTRACTION 审中-公开
标题翻译：用于组合蛋白质沉淀和固相萃取的组合物和方法
公开(公告)号：US20080213906A1
公开(公告)日：2008-09-04
申请号：US12019445
申请日：2008-01-24
申请人： Craig Aurand , Charles Mi , Paul Ross , An Trinh , Hillel Brandes , Michael Ye
发明人： Craig Aurand , Charles Mi , Paul Ross , An Trinh , Hillel Brandes , Michael Ye
IPC分类号： G01N33/84
CPC分类号： G01N30/6091 , B01J20/06 , B01J20/103 , B01J20/3204 , B01J20/3208 , B01J20/3236
摘要： A composition, method and device for the preparation of biological samples for subsequent LC-MS analysis using a combined and concurrent protein precipitation and solid phase extraction (SPE) process is described. Through an integrated combination of protein precipitation, filtration, and SPE using a novel zirconia-coated chromatographic media, interfering compounds, such as proteins and phosphate-containing compounds, are eliminated from the biological samples, affording a higher degree of analyte response during LC-MS analysis.
摘要翻译：描述了使用组合和同时蛋白沉淀和固相萃取（SPE）方法制备用于后续LC-MS分析的生物样品的组合物，方法和装置。通过使用新型氧化锆涂层色谱介质，蛋白质沉淀，过滤和SPE的综合组合，从生物样品中除去干扰化合物，如蛋白质和含磷酸盐化合物，在LC- MS分析。

10. 外观设计

USD393744S Holster for a pager 失效
公开(公告)号：USD393744S
公开(公告)日：1998-04-28
申请号：US59717
申请日：1996-08-30
申请人： Henry Wandt , Michael Ye , Zhihong Memphis Yin , Tek Choy Kok , Daniel Troutman , Donald Guthan , Mark Palm
设计人： Henry Wandt , Michael Ye , Zhihong Memphis Yin , Tek Choy Kok , Daniel Troutman , Donald Guthan , Mark Palm

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