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    • 4. 发明申请
    • Aqueous Alcoholic Microbicidal Compositions Comprising Copper Ions
    • 含有铜离子的含水酒精杀微生物组合物
    • US20140161905A1
    • 2014-06-12
    • US14122502
    • 2012-05-18
    • Mohammad Khalid IjazJoseph RubinoYun-Peng Zhu
    • Mohammad Khalid IjazJoseph RubinoYun-Peng Zhu
    • A01N31/02A01N41/04A01N55/02A01N59/20A01N33/12
    • A01N31/02A01N33/12A01N41/04A01N55/02A01N59/20A01N2300/00
    • Liquid treatment compositions comprise (or in certain preferred embodiments may consist essentially of, or may consist of): a copper source material which releases copper ions into the treatment composition, at least one alcohol which independently of other constituents present exhibits a microbicidal effect, at least one quaternary ammonium compound which provides a microbicidal benefit, optionally but very preferably also at least one detersive surfactant, further optionally one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions, including one or more detersive surfactants, and water, wherein the compositions are at a pH such that the surface treatment compositions, exhibit a microbicidal or germicidal or antimicrobial effect on treated inanimate surfaces or when used to treat an airspace, e.g. ambient air, characterized in exhibiting a microbicidal benefit when tested against one or more challenge microorganisms, preferably against Poliovirus type 1 Sabin (“PV1”), according to one or more of the following standardized test protocols: ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN13697, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17th Ed. (2000).
    • 液体处理组合物包含(或在某些优选实施方案中可基本上由或可由其构成):将铜离子释放到处理组合物中的铜源材料,至少一种独立于其它组分的醇显示出杀微生物作用, 提供杀微生物益处的至少一种季铵化合物,任选但非常优选至少一种去污表面活性剂,进一步任选地一种或多种赋予组合物一种或多种有利的技术或美学益处的其它成分,包括一种或多种去污表面活性剂, 和水,其中组合物处于pH使得表面处理组合物在处理的无生物表面上或当用于处理空域时表现出杀微生物剂或杀菌或抗微生物作用,例如 环境空气,其特征在于根据一种或多种下列标准化测试方案,针对一种或多种攻击微生物,优选地针对脊髓灰质炎病毒1型Sabin(“PV1”)进行测试时显示出杀微生物益处:ASTM E1052标准测试方法 针对病毒的悬浮液的抗微生物剂或ASTM E1053标准测试方法,用于评估用于消毒无生命,无孔环境表面的化学品或欧洲标准表面测试,EN13697或AOAC杀菌喷雾产品作为消毒剂测试方法,AOAC指数, 第17版 (2000)。
    • 5. 发明申请
    • Sprayable Aqueous Microbicidal Compositions Comprising Copper Ions
    • 包含铜离子的可喷洒水性杀微生物组合物
    • US20140140935A1
    • 2014-05-22
    • US14122487
    • 2012-05-18
    • Mohammad Khalid IjazJoseph RubinoYun-Peng Zhu
    • Mohammad Khalid IjazJoseph RubinoYun-Peng Zhu
    • A01N25/06A01N33/12A01N31/02A01N59/20
    • A01N25/06A01N31/02A01N33/12A01N59/20A01N2300/00
    • Disclosed are sprayable, pressurized inanimate surface and air liquid treatment compositions which impart a microbicidal benefit to treated surfaces which compositions comprise (or in certain preferred embodiments may consist essentially of, or may consist of): a copper source material which releases copper ions into the treatment composition, preferably a source of Cu(I) and/or Cu(II) ions; at least one quaternary ammonium compound which provides a microbicidal benefit; a propellant; and, water. The compositions may further optionally include one or more further optional constituents such as a detersive surfactant and/or minor amounts of a lower alkyl aliphatic monohydric alcohol in order to impart one or more advantageous technical or aesthetic benefits to the compositions, including one or more detersive surfactants; wherein the composition has a pH of at least 5, wherein the treatment compositions are characterized in exhibiting a microbicidal benefit when tested against one or more challenge microorganisms, preferably against Poliovirus type 1 Sabin (“PV1”), according to one or more of the following standardized test protocols: ASTM E1052-96(2002) Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053-11 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN13697, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17th Ed. (2000) against one or more challenge microorganisms.
    • 公开了可喷雾的,无压缩的无生命的表面和空气液体处理组合物,其对处理的表面赋予杀微生物益处,所述组合物包含(或在某些优选实施方案中可基本由或可由其构成):将铜离子释放到 处理组合物,优选Cu(I)和/或Cu(II)离子源; 至少一种提供杀微生物益处的季铵化合物; 推进剂; 和水。 组合物可以进一步任选地包括一种或多种另外的任选组分,例如去污表面活性剂和/或少量的低级烷基脂族一元醇,以赋予组合物一种或多种有利的技术或美学益处,包括一种或多种去污剂 表面活性剂 其中所述组合物具有至少5的pH,其中所述处理组合物的特征在于针对一种或多种攻击微生物,优选地针对脊髓灰质炎病毒1型Sabin(“PV1”)进行测试时显示出杀微生物益处,根据一种或多种 以下标准化测试方案:ASTM E1052-96(2002)抗微生物剂对悬浮液中的病毒的功效的标准测试方法,或ASTM E1053-11标准测试方法,用于评估用于消毒无生命,无孔环境表面的化学物质的杀病毒活性,或 欧洲标准表面试验,EN13697或作为消毒剂试验方法的AOAC杀菌喷雾产品,AOAC指数,第17版。 (2000)针对一种或多种攻击微生物。
    • 6. 发明申请
    • Antimicrobial Hand Soap Composition
    • 抗菌手皂组成
    • US20130210923A1
    • 2013-08-15
    • US13520903
    • 2010-12-14
    • Yun-Peng Zhu
    • Yun-Peng Zhu
    • A61K8/41A61Q19/10
    • A61K8/416A61K8/39A61K8/40A61K8/44A61K8/442A61K2800/30A61Q17/005A61Q19/10C11D1/62C11D1/65C11D3/0026C11D3/48C11D17/08
    • Topical aqueous liquid compositions for application to the epidermis which provide a germicidal benefit thereto comprising: 0.02-10% wt. of a germicidally effective amount of a quaternary ammonium surfactant compound, 0.1-25% wt. of at least one anionic surfactant constituent which excludes anionic surfactants of the sulfate and sulfonate types, 0.1-15% wt. of a cationic conditioner constituent, 0-10% wt. of a foam stabilizer constituent; at least 70% wt. of water, and optionally one or more of optional constituents which may be used to impart an aesthetic benefit, e.g., color, fragrance, or a further technical benefit, e.g., viscosity adjustment, to the liquid compositions, characterized in that: (a) the weight ratio of the germicidally effective quaternary ammonium and cationic conditioner constituent to the anionic surfactant constituent is not less than 0.6; and/or, (b) the weight ratio of the germicidally effective quaternary ammonium surfactant compound to the cationic conditioner constituent is less than 0.14; and/or, (c) the ratio of the cationic conditioner constituent to the anionic surfactant constituent is at least 0.5; and, (d) the pH of the liquid composition is between about 3.5 and about 7.5.
    • 用于施用于表皮的局部含水液体组合物,其提供杀菌效果,其包含:0.02-10重量% 的杀菌有效量的季铵表面活性剂化合物,0.1-25重量% 的至少一种阴离子表面活性剂组分,其排除硫酸盐和磺酸盐类型的阴离子表面活性剂,0.1-15重量% 的阳离子调理剂组分,0-10重量% 的泡沫稳定剂组分; 至少70重量% 的水,以及任选的一种或多种任选的组分,其可用于赋予液体组合物美学益处,例如颜色,香料或其它技术优点,例如粘度调节,其特征在于:(a) 杀菌有效的季铵盐和阳离子调理剂组分与阴离子表面活性剂组分的重量比不小于0.6; 和/或(b)杀菌有效季铵表面活性剂化合物与阳离子调理剂成分的重量比小于0.14; 和/或(c)阳离子调理剂组分与阴离子表面活性剂组分的比例至少为0.5; 和(d)液体组合物的pH在约3.5至约7.5之间。
    • 8. 发明申请
    • TOPICAL GERMICIDAL COMPOSITIONS
    • 局部杀菌组合物
    • US20130210929A1
    • 2013-08-15
    • US13700893
    • 2011-06-15
    • Yun-Peng Zhu
    • Yun-Peng Zhu
    • A61K9/00A61K31/045
    • A61K9/0014A01N31/02A61K8/34A61K8/345A61K8/8152A61K8/8158A61K31/045A61K2800/5426A61Q17/005A01N25/02A01N25/04A01N2300/00
    • Topical germicidal compositions for application to the epidermis comprise: 50-85% wt, of an alcohol constituent comprising one or more C1-C4 monohydric alcohols, and preferably wherein ethanol comprises the bulk of the alcohol constituent; a humectant, a cationic polymer constituent, preferably a Polyquaternium type cationic polymer; an anionic opacifier constituent, optionally, one or more further constituents for improving the aesthetic or other technical features of the invention; and, water, wherein the composition is flowable and preferably also exhibits an initial viscosity (“as.mixed”) of 10-100,000 cP at 25° C., and subsequent to being stored at elevated temperatures and/or extended time intervals are retained as a single phase composition and do not split or separate into two or more phases, and further wherein, the cationic polymer constituent (and where present, further cationic compounds) and the anionic opacifier constituent, are present in respective weight ratios of in the range of at least about 0.9:1.
    • 用于表皮的局部杀菌组合物包含:50-85重量%的包含一种或多种C 1 -C 4一元醇的醇组分,优选其中乙醇包含大部分醇组分; 保湿剂,阳离子聚合物成分,优选聚季铵盐型阳离子聚合物; 阴离子遮光剂组分,任选地一种或多种用于改善本发明的美学或其它技术特征的其它组分; 和水,其中组合物是可流动的,并且优选在25℃下表现出10-100,000cP的初始粘度(“as.mixed”),并且随后在升高的温度和/或延长的时间间隔保存 作为单相组合物并且不分裂或分离成两个或多个相,并且其中阳离子聚合物组分(和其中存在的其它阳离子化合物)和阴离子遮光剂组分以各自的重量比存在 至少约0.9:1。