专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09862764B2 Compositions and methods for antibodies targeting BMP6 有权
公开(公告)号：US09862764B2
公开(公告)日：2018-01-09
申请号：US14974318
申请日：2015-12-18
申请人： Feng Cong , William Dietrich , Nathalie George , Dong Liu , Asher Schachter , Aditi Soni , Jing Zhou
发明人： Feng Cong , William Dietrich , Nathalie George , Dong Liu , Asher Schachter , Aditi Soni , Jing Zhou
IPC分类号： A61K39/00 , A61K39/395 , C12N1/15 , C12N1/21 , C12N5/10 , C12N15/13 , C12N15/63 , C07K16/00 , C07K16/18 , C07K16/22 , A61K38/18
CPC分类号： C07K16/22 , A61K38/1816 , A61K39/3955 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/40 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/76 , C07K2317/90 , C07K2317/92
摘要： The present invention relates to antibodies and antigen-binding fragments thereof to human BMP6 and compositions and methods of use thereof.

2. 发明授权

US07666612B2 Methods for protein labeling based on acyl carrier protein 有权
标题翻译：基于酰基载体蛋白的蛋白质标记方法
公开(公告)号：US07666612B2
公开(公告)日：2010-02-23
申请号：US10557897
申请日：2004-05-19
申请人： Kai Johnsson , Nathalie George
发明人： Kai Johnsson , Nathalie George
IPC分类号： G01N33/53 , C07K14/00
CPC分类号： C07K14/245 , C07K2319/21 , C07K2319/43 , G01N33/535 , G01N33/581
摘要： A method for labeling acyl carrier protein (ACP) fusion proteins with a wide variety of different labels is disclosed. The method relies on the transfer of a label from a coenzyme A type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homologue thereof. The method allows detecting and manipulating the fusion protein, both in vitro and in vivo, by attaching molecules to the fusion proteins that introduce a new physical or chemical property to the fusion protein. Examples of such labels are, among others, spectroscopic probes or reporter molecules, affinity tags, molecules generating reactive radicals, cross-linkers, ligands mediating protein-protein interactions or molecules suitable for the immobilization of the fusion protein.
摘要翻译：公开了用多种不同标记物标记酰基载体蛋白（ACP）融合蛋白的方法。该方法依赖于使用全酰基载体蛋白合成酶（ACPS）或其同源物将标记从辅酶A型底物转移至ACP融合蛋白。该方法允许在体外和体内检测和操纵融合蛋白，通过将融合蛋白连接到融合蛋白上，向融合蛋白引入新的物理或化学性质。此类标记的实例包括光谱探针或报告分子，亲和标签，产生反应性基团的分子，交联剂，介导蛋白质 - 蛋白质相互作用的配体或适用于固定融合蛋白的分子。

3. 发明申请

US20100173384A1 METHODS FOR PROTEIN LABELING BASED ON ACYL CARRIER PROTEIN 有权
标题翻译：基于ACYL载体蛋白的蛋白质标记方法
公开(公告)号：US20100173384A1
公开(公告)日：2010-07-08
申请号：US12647778
申请日：2009-12-28
申请人： Kai JOHNSSON , Nathalie George
发明人： Kai JOHNSSON , Nathalie George
IPC分类号： C12N9/96 , C07K1/00 , C07K16/46 , C07K14/00
CPC分类号： C07K14/245 , C07K2319/21 , C07K2319/43 , G01N33/535 , G01N33/581
摘要： A method for labeling acyl carrier protein (ACP) fusion proteins with a wide variety of different labels is disclosed. The method relies on the transfer of a label from a coenzyme A type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homologue thereof. The method allows detecting and manipulating the fusion protein, both in vitro and in vivo, by attaching molecules to the fusion proteins that introduce a new physical or chemical property to the fusion protein. Examples of such labels are, among others, spectroscopic probes or reporter molecules, affinity tags, molecules generating reactive radicals, cross-linkers, ligands mediating protein-protein interactions or molecules suitable for the immobilization of the fusion protein.
摘要翻译：公开了用多种不同标记物标记酰基载体蛋白（ACP）融合蛋白的方法。该方法依赖于使用全酰基载体蛋白合成酶（ACPS）或其同源物将标记从辅酶A型底物转移至ACP融合蛋白。该方法允许在体外和体内检测和操纵融合蛋白，通过将融合蛋白连接到融合蛋白上，向融合蛋白引入新的物理或化学性质。此类标记的实例包括光谱探针或报告分子，亲和标签，产生反应性基团的分子，交联剂，介导蛋白质 - 蛋白质相互作用的配体或适用于固定融合蛋白的分子。

4. 发明申请

US20070082336A1 Methods for protein labeling based on acyl carrier protein 有权
标题翻译：基于酰基载体蛋白的蛋白质标记方法
公开(公告)号：US20070082336A1
公开(公告)日：2007-04-12
申请号：US10557897
申请日：2004-05-19
申请人： Kai Johnsson , Nathalie George
发明人： Kai Johnsson , Nathalie George
IPC分类号： C12Q1/68 , C07J17/00 , G01N33/554 , C07H19/04 , C07H21/04
CPC分类号： C07K14/245 , C07K2319/21 , C07K2319/43 , G01N33/535 , G01N33/581
摘要： A method for labeling acyl carrier protein (ACP) fusion proteins with a wide variety of different labels is disclosed. The method relies on the transfer of a label from a coenzyme A type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homologue thereof. The method allows detecting and manipulating the fusion protein, both in vitro and in vivo, by attaching molecules to the fusion proteins that introduce a new physical or chemical property to the fusion protein. Examples of such labels are, among others, spectroscopic probes or reporter molecules, affinity tags, molecules generating reactive radicals, cross-linkers, ligands mediating protein-protein interactions or molecules suitable for the immobilization of the fusion protein.
摘要翻译：公开了用多种不同标记物标记酰基载体蛋白（ACP）融合蛋白的方法。该方法依赖于使用全酰基载体蛋白合成酶（ACPS）或其同源物将标记从辅酶A型底物转移至ACP融合蛋白。该方法允许在体外和体内检测和操纵融合蛋白，通过将融合蛋白连接到融合蛋白上，向融合蛋白引入新的物理或化学性质。此类标记的实例包括光谱探针或报告分子，亲和标签，产生反应性基团的分子，交联剂，介导蛋白质 - 蛋白质相互作用的配体或适用于固定融合蛋白的分子。

5. 发明授权

US08476031B2 Methods for protein labeling based on acyl carrier protein 有权
标题翻译：基于酰基载体蛋白的蛋白质标记方法
公开(公告)号：US08476031B2
公开(公告)日：2013-07-02
申请号：US12647778
申请日：2009-12-28
申请人： Kai Johnsson , Nathalie George
发明人： Kai Johnsson , Nathalie George
IPC分类号： G01N33/53 , C07K14/00
CPC分类号： C07K14/245 , C07K2319/21 , C07K2319/43 , G01N33/535 , G01N33/581
摘要： A method for labeling acyl carrier protein (ACP) fusion proteins with a wide variety of different labels is disclosed. The method relies on the transfer of a label from a coenzyme A type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homologue thereof. The method allows detecting and manipulating the fusion protein, both in vitro and in vivo, by attaching molecules to the fusion proteins that introduce a new physical or chemical property to the fusion protein. Examples of such labels are, among others, spectroscopic probes or reporter molecules, affinity tags, molecules generating reactive radicals, cross-linkers, ligands mediating protein-protein interactions or molecules suitable for the immobilization of the fusion protein.
摘要翻译：公开了用多种不同标记物标记酰基载体蛋白（ACP）融合蛋白的方法。该方法依赖于使用全酰基载体蛋白合成酶（ACPS）或其同源物将标记从辅酶A型底物转移至ACP融合蛋白。该方法允许在体外和体内检测和操纵融合蛋白，通过将融合蛋白连接到融合蛋白上，向融合蛋白引入新的物理或化学性质。此类标记的实例包括光谱探针或报告分子，亲和标签，产生反应性基团的分子，交联剂，介导蛋白质 - 蛋白质相互作用的配体或适用于固定融合蛋白的分子。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式