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    • 1. 发明授权
    • Stretchable anti-buckling coiled-sheet stent
    • 可伸缩抗弯卷盘支架
    • US06632240B2
    • 2003-10-14
    • US09932079
    • 2001-08-17
    • Farhad KhosraviHimanshu N. PatelJohn Spiridigliozzi
    • Farhad KhosraviHimanshu N. PatelJohn Spiridigliozzi
    • A61F206
    • A61F2/07A61F2/848A61F2/89A61F2/91A61F2/915A61F2/92A61F2/958A61F2002/065A61F2002/072A61F2002/075A61F2002/8486A61F2220/0008A61F2220/0016A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0054A61F2250/0039
    • A stent-graft having an exo-skeleton attached to a tubular graft, the tubular graft having a peripheral wall defining a lumen therein extending between first and second ends. The exo-skeleton may assume contracted and enlarged conditions, and includes one or more serpentine elements, each extending both peripherally and axially along at least a portion of the peripheral wall. Coiled-sheet stents are provided on the ends of the tubular graft for anchoring the ends within a body passage. Each serpentine element is a zigzag structure extending peripherally about the peripheral wall, with a plurality of serpentine elements distributed axially along the peripheral wall. The serpentine elements are individually attached to the peripheral wall and/or connector elements may extend between adjacent serpentine elements. Alternatively, each serpentine element may define a generally sinusoidal shape extending axially along the peripheral wall. The tubular graft may have a bifurcated end from which a tubular graft extension segment may extend and to which a docking limb may be attached. A plurality of serpentine elements may also be attached to the extension segment and the docking limb.
    • 具有附着到管状移植物上的外骨骼的支架移植物,所述管状移植物具有在第一和第二端之间限定内腔的周边壁。 外骨骼可以承担收缩和扩大的条件,并且包括一个或多个蛇形元件,每个沿着周壁的至少一部分周向和轴向地延伸。 螺旋片支架设置在管状移植物的端部上,用于将端部固定在体通道内。 每个蛇形元件是绕周边延伸的锯齿形结构,其中多个蛇形元件沿周壁轴向分布。 蛇形元件单独地附接到周壁,并且/或连接器元件可以在相邻的蛇形元件之间延伸。 或者,每个蛇形元件可以限定沿着周壁轴向延伸的大致正弦形状。 管状移植物可以具有分叉端,管状移植物延伸段可从该分叉端延伸并且对接肢可以附接到该端部。 多个蛇形元件也可以附接到延伸段和对接肢体。
    • 2. 发明授权
    • Stretchable anti-buckling coiled-sheet stent
    • 可伸缩抗弯卷盘支架
    • US07641683B2
    • 2010-01-05
    • US11675040
    • 2007-02-14
    • Farhad KhosraviHimanshu N. PatelJohn Spiridigliozzi
    • Farhad KhosraviHimanshu N. PatelJohn Spiridigliozzi
    • A61F2/06
    • A61F2/07A61F2/848A61F2/89A61F2/91A61F2/915A61F2/92A61F2/958A61F2002/065A61F2002/072A61F2002/075A61F2002/8486A61F2220/0008A61F2220/0016A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0054A61F2250/0039
    • A stent-graft having an exo-skeleton attached to a tubular graft, the tubular graft having a peripheral wall defining a lumen therein extending between first and second ends. The exo-skeleton may assume contracted and enlarged conditions, and includes one or more serpentine elements, each extending both peripherally and axially along at least a portion of the peripheral wall. Coiled-sheet stents are provided on the ends of the tubular graft for anchoring the ends within a body passage. Each serpentine element is a zigzag structure extending peripherally about the peripheral wall, with a plurality of serpentine elements distributed axially along the peripheral wall. The serpentine elements are individually attached to the peripheral wall and/or connector elements may extend between adjacent serpentine elements. Alternatively, each serpentine element may define a generally sinusoidal shape extending axially along the peripheral wall. The tubular graft may have a bifurcated end from which a tubular graft extension segment may extend and to which a docking limb may be attached. A plurality of serpentine elements may also be attached to the extension segment and the docking limb.
    • 具有附着到管状移植物上的外骨骼的支架移植物,所述管状移植物具有在第一和第二端之间限定内腔的周边壁。 外骨骼可以承担收缩和扩大的条件,并且包括一个或多个蛇形元件,每个沿着周壁的至少一部分周向和轴向地延伸。 螺旋片支架设置在管状移植物的端部上,用于将端部固定在体通道内。 每个蛇形元件是绕周边延伸的锯齿形结构,其中多个蛇形元件沿周壁轴向分布。 蛇形元件单独地附接到周壁,并且/或连接器元件可以在相邻的蛇形元件之间延伸。 或者,每个蛇形元件可以限定沿着周壁轴向延伸的大致正弦形状。 管状移植物可以具有分叉端,管状移植物延伸段可从该分叉端延伸并且对接肢可以附接到该端部。 多个蛇形元件也可以附接到延伸段和对接肢。
    • 3. 发明授权
    • Coiled-sheet stent-graft with slidable exo-skeleton
    • 具有可滑动外骨架的卷片支架移植物
    • US06322585B1
    • 2001-11-27
    • US09288866
    • 1999-04-09
    • Farhad KhosraviHimanshu N. Patel
    • Farhad KhosraviHimanshu N. Patel
    • A61F206
    • A61F2/92A61F2/07A61F2/848A61F2/89A61F2/91A61F2/915A61F2/954A61F2/958A61F2002/065A61F2002/075A61F2002/8486A61F2210/0076A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0013A61F2230/0054A61F2250/0039
    • A stent-graft having an exo-skeleton attached to a tubular graft, the tubular graft having a peripheral wall defining a lumen therein extending between first and second ends. One or more support elements, defining the exo-skeleton, are attached to the tubular graft, each support element extending generally peripherally around the tubular graft, each support element including generally axial segments and generally peripheral segments. A plurality of first fasteners attach the plurality of support elements to the wall of the tubular graft, at least one generally axial segment being slidably engaged by each first fastener. A plurality of second fasteners also attach the plurality of support elements to the wall of the tubular graft, each second fastener substantially anchoring a generally peripheral segment of the respective support element to the wall of the tubular graft. The stent-graft also includes first and second stents on the first and second ends for substantially anchoring the respective ends within a body passage.
    • 具有附着到管状移植物上的外骨骼的支架移植物,所述管状移植物具有在第一和第二端之间限定内腔的周边壁。 限定外骨架的一个或多个支撑元件附接到管状移植物,每个支撑元件围绕管状移植物大致周边延伸,每个支撑元件包括大致轴向的段和大体上的周边段。 多个第一紧固件将多个支撑元件连接到管状移植物的壁上,至少一个大致轴向的段与每个第一紧固件可滑动地接合。 多个第二紧固件还将多个支撑元件附接到管状移植物的壁上,每个第二紧固件基本上将相应支撑元件的大致周边的段固定到管状移植物的壁上。 支架移植物还包括在第一和第二端部上的第一和第二支架,用于将相应端部基本上固定在主体通道内。
    • 4. 发明授权
    • Coiled-sheet stent-graft with slidable exo-skeleton
    • 具有可滑动外骨架的卷片支架移植物
    • US07731743B2
    • 2010-06-08
    • US11361155
    • 2006-02-24
    • Farhad KhosraviHimanshu N. Patel
    • Farhad KhosraviHimanshu N. Patel
    • A61F2/06
    • A61F2/07A61F2/848A61F2/89A61F2/91A61F2/915A61F2/92A61F2/958A61F2002/065A61F2002/072A61F2002/075A61F2002/8486A61F2220/0008A61F2220/0016A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0054A61F2250/0039
    • A stent-graft having an exo-skeleton attached to a tubular graft, the tubular graft having a peripheral wall defining a lumen therein extending between first and second ends. One or more support elements, defining the exo-skeleton, are attached to the tubular graft, each support element extending generally peripherally around the tubular graft, each support element including generally axial segments and generally peripheral segments. A plurality of first fasteners attach the plurality of support elements to the wall of the tubular graft, at least one generally axial segment being slidably engaged by each first fastener. A plurality of second fasteners also attach the plurality of support elements to the wall of the tubular graft, each second fastener substantially anchoring a generally peripheral segment of the respective support element to the wall of the tubular graft. The stent-graft also includes first and second stents on the first and second ends for substantially anchoring the respective ends within a body passage.
    • 具有附着到管状移植物上的外骨骼的支架移植物,所述管状移植物具有在第一和第二端之间限定内腔的周边壁。 限定外骨架的一个或多个支撑元件附接到管状移植物,每个支撑元件围绕管状移植物大致周边延伸,每个支撑元件包括大致轴向的段和大体上的周边段。 多个第一紧固件将多个支撑元件连接到管状移植物的壁上,至少一个大致轴向的段与每个第一紧固件可滑动地接合。 多个第二紧固件还将多个支撑元件附接到管状移植物的壁上,每个第二紧固件基本上将相应支撑元件的大致周边的段固定到管状移植物的壁上。 支架移植物还包括在第一和第二端部上的第一和第二支架,用于将相应端部基本上固定在主体通道内。
    • 5. 发明授权
    • Stretchable anti-buckling coiled-sheet stent
    • 可伸缩抗弯卷盘支架
    • US07179284B2
    • 2007-02-20
    • US10638040
    • 2003-08-08
    • Farhad KhosraviHimanshu N. PatelJohn Spiridigliozzi
    • Farhad KhosraviHimanshu N. PatelJohn Spiridigliozzi
    • A61F2/06
    • A61F2/07A61F2/848A61F2/89A61F2/91A61F2/915A61F2/92A61F2/958A61F2002/065A61F2002/072A61F2002/075A61F2002/8486A61F2220/0008A61F2220/0016A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0054A61F2250/0039
    • A stent-graft having an exo-skeleton attached to a tubular graft, the tubular graft having a peripheral wall defining a lumen therein extending between first and second ends. The exo-skeleton may assume contracted and enlarged conditions, and includes one or more serpentine elements, each extending both peripherally and axially along at least a portion of the peripheral wall. Coiled-sheet stents are provided on the ends of the tubular graft for anchoring the ends within a body passage. Each serpentine element is a zigzag structure extending peripherally about the peripheral wall, with a plurality of serpentine elements distributed axially along the peripheral wall. The serpentine elements are individually attached to the peripheral wall and/or connector elements may extend between adjacent serpentine elements. Alternatively, each serpentine element may define a generally sinusoidal shape extending axially along the peripheral wall. The tubular graft may have a bifurcated end from which a tubular graft extension segment may extend and to which a docking limb may be attached. A plurality of serpentine elements may also be attached to the extension segment and the docking limb.
    • 具有附着到管状移植物上的外骨骼的支架移植物,所述管状移植物具有在第一和第二端之间限定内腔的周边壁。 外骨骼可以承担收缩和扩大的条件,并且包括一个或多个蛇形元件,每个沿着周壁的至少一部分周向和轴向地延伸。 螺旋片支架设置在管状移植物的端部上,用于将端部固定在体通道内。 每个蛇形元件是绕周边延伸的锯齿形结构,其中多个蛇形元件沿周壁轴向分布。 蛇形元件单独地附接到周壁,并且/或连接器元件可以在相邻的蛇形元件之间延伸。 或者,每个蛇形元件可以限定沿着周壁轴向延伸的大致正弦形状。 管状移植物可以具有分叉端,管状移植物延伸段可从该分叉端延伸并且对接肢可以附接到该端部。 多个蛇形元件也可以附接到延伸段和对接肢。
    • 6. 发明授权
    • Flexible, stretchable coiled-sheet stent
    • 弹性,伸缩性卷盘支架
    • US07731745B2
    • 2010-06-08
    • US10960328
    • 2004-10-06
    • Yi YangFarhad KhosraviHimanshu N. Patel
    • Yi YangFarhad KhosraviHimanshu N. Patel
    • A61F2/06A61M29/00
    • A61F2/91A61F2/915A61F2/92A61F2002/91533A61F2002/91541A61F2002/91558A61F2220/0008A61F2220/0016
    • A coiled-sheet stent includes a tubular body having a longitudinal axis and a circumference, and a plurality of cylindrical bands formed in the tubular body, each band having a zig-zag pattern including a series of sequential diagonal elements connected to one another and extending about the circumference. A plurality of longitudinal connectors extend between and connect adjacent bands. The diagonal elements have an arcuate shape, all diagonal elements in each band being oriented in either a clockwise or counter-clockwise direction about the circumference. The tubular body is expandable between contracted and enlarged conditions, and the zig-zag pattern is expandable between unstretched and unstretched conditions, the zig-zag pattern being biased towards the stretched condition above a transition temperature, thereby at least partially defining the enlarged condition. A multi-cellular stent structure is also provided that includes a plurality of bat shaped cells formed in a tubular body, each cell defining a head region, a tail region and opposing curved wing regions, and a plurality of connectors extending between and connecting adjacent cells. The head and tail regions of adjacent cells are directly connected to one another, and connectors extend between adjacent wing regions of adjacent cells.
    • 螺旋片支架包括具有纵向轴线和圆周的管状体,以及形成在管状体中的多个圆柱形带,每个带具有包括一系列相互连接并延伸的顺序对角线元件的之字形图案 围绕圆周。 多个纵向连接器在相邻带之间延伸并连接相邻带。 对角元件具有弓形形状,每个带中的所有对角元件围绕圆周以顺时针或逆时针方向定向。 管状体在收缩和扩大的条件之间是可膨胀的,并且之字形图案可在未拉伸和未拉伸状态之间扩展,之字形图案被偏压到高于转变温度的拉伸状态,从而至少部分限定扩大状态。 还提供了一种多细胞支架结构,其包括形成在管状体中的多个蝙蝠形细胞,每个细胞限定头部区域,尾部区域和相对的弯曲翼状区域,以及在相邻细胞之间延伸并连接相邻细胞的多个连接器 。 相邻单元的头部和尾部区域彼此直接连接,并且连接器在相邻单元的相邻机翼区域之间延伸。
    • 8. 发明授权
    • Coiled-sheet stent-graft with exo-skeleton
    • 具有外骨架的片状支架移植物
    • US06325820B1
    • 2001-12-04
    • US09192977
    • 1998-11-16
    • Farhad KhosraviHimanshu N. Patel
    • Farhad KhosraviHimanshu N. Patel
    • A61F206
    • A61F2/07A61F2/848A61F2/89A61F2/91A61F2/915A61F2/92A61F2/958A61F2002/065A61F2002/072A61F2002/075A61F2002/8486A61F2220/0008A61F2220/0016A61F2220/005A61F2220/0066A61F2220/0075A61F2230/0054A61F2250/0039
    • A stent-graft having an exo-skeleton attached to a tubular graft, the tubular graft having a peripheral wall defining a lumen therein extending between first and second ends. The exo-skeleton may assume contracted and enlarged conditions, and includes one or more serpentine elements, each extending both peripherally and axially along at least a portion of the peripheral wall. Coiled-sheet stents are provided on the ends of the tubular graft for anchoring the ends within a body passage. Each serpentine element is a zigzag structure extending peripherally about the peripheral-wall, with a plurality of serpentine elements distributed axially along the peripheral wall. The serpentine elements are individually attached to the peripheral wall and/or connector elements may extend between adjacent serpentine elements. Alternatively, each serpentine element may define a generally sinusoidal shape extending axially along the peripheral wall. The tubular graft may have a bifurcated end from which a tubular graft extension segment may extend and to which a docking limb may be attached. A plurality of serpentine elements may also be attached to the extension segment and the docking limb.
    • 具有附着到管状移植物上的外骨骼的支架移植物,所述管状移植物具有在第一和第二端之间限定内腔的周边壁。 外骨骼可以承担收缩和扩大的条件,并且包括一个或多个蛇形元件,每个沿着周壁的至少一部分周向和轴向地延伸。 螺旋片支架设置在管状移植物的端部上,用于将端部固定在体通道内。 每个蛇形元件是绕周边延伸的锯齿形结构,多个蛇形元件沿周壁轴向分布。 蛇形元件单独地附接到周壁,并且/或连接器元件可以在相邻的蛇形元件之间延伸。 或者,每个蛇形元件可以限定沿着周壁轴向延伸的大致正弦形状。 管状移植物可以具有分叉端,管状移植物延伸段可从该分叉端延伸并且对接肢可以附接到该端部。 多个蛇形元件也可以附接到延伸段和对接肢。
    • 10. 发明授权
    • Stretchable anti-buckling coiled-sheet stent
    • 可伸缩抗弯卷盘支架
    • US08092514B1
    • 2012-01-10
    • US09427260
    • 1999-10-25
    • Farhad KhosraviHimanshu N. PatelYi Yang
    • Farhad KhosraviHimanshu N. PatelYi Yang
    • A61F2/06
    • A61F2/92A61F2/91A61F2220/0008A61F2220/0016A61F2230/0054A61F2230/008A61F2250/0018
    • A stent includes a coiled-up sheet having overlapping inner and outer longitudinal sections extending parallel to a longitudinal axis thereof, and defining a periphery, the coiled-up sheet being unrollable between contracted and enlarged conditions. A plurality of stretchable elements are formed in the coiled-up sheet, the stretchable elements being expandable about the periphery between an unstretched condition to facilitate placement in a delivery device in the contracted condition and a stretched condition to facilitate expansion of the coiled-up sheet to the enlarged condition upon deployment from the delivery device. Preferably, the coiled-up sheet is biased to the enlarged condition, and the stretchable elements are biased to the stretched condition. More preferably, at least one of the biases is provided by a shape memory property of the coiled-up sheet, which is activated by exposing the stent to body temperature.
    • 支架包括具有与其纵向轴线平行延伸的重叠的内部和外部纵向部分并且限定周边的盘绕的片材,所述盘绕的片材在收缩和扩大的条件之间不可展开。 多个可拉伸元件形成在盘绕的片材中,可拉伸元件可以在未拉伸状态下围绕周边扩张,以便于在收缩状态下放置在输送装置中,并且拉伸条件以便于卷起片材的膨胀 在从输送装置部署时变为放大状态。 优选地,盘绕的片材被偏压到放大状态,并且可拉伸元件被偏压到拉伸状态。 更优选地,通过将​​支架暴露于体温而被活化的卷曲片的形状记忆特性提供至少一个偏差。