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1. 发明专利

JPH11293528A PRODUCTION OF FIBER BUNDLE AND APPARATUS THEREFOR 失效
公开(公告)号：JPH11293528A
公开(公告)日：1999-10-26
申请号：JP2118099
申请日：1999-01-29
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： GRAF THOMAS , HERMANN JOSEF , HEILMANN KLAUS
IPC分类号： D01G1/04 , D01G99/00
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a fiber bundle, capable of carrying out a continuous treatment and avoiding the majority of the loss of fiber, and an apparatus for carrying out the method. SOLUTION: This method for producing a fiber bundle is provided with a process for picking up and transporting one or more fiber bundle strands by one or more supply elements 20, a process for cutting the fiber bundle strands into partial bundles 10 of proper length and a process for releasing the partial bundles 10 from the supply elements 20, gripping the partial bundles 10 by one or more gripping elements 30 and releasing the partial bundles 10 from the gripping elements 30 and is capable of carrying out a continuous treatment and reducing the fiber loss.

2. 发明专利

JP2001029456A METHOD FOR DETERMINING EFFICIENCY OF DIALYZER OF DIALYZING APPARATUS AND DIALYZING APPARATUS FOR EFFECTING THE SAME 失效
公开(公告)号：JP2001029456A
公开(公告)日：2001-02-06
申请号：JP2000187223
申请日：2000-06-22
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： GRAF THOMAS , BARDORZ CHRISTOPH , GROS MALTE , GOLDAU RAINER
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34 , B01D61/28 , B01D61/34
摘要： PROBLEM TO BE SOLVED: To provide a method for monitoring the efficiency of a dialyzer during dialysis using a simple process without a time delay, and a dialyzing apparatus capable of monitoring the efficiency of the dialyzer using a simple process without a time delay. SOLUTION: In this method and apparatus for determining the efficiency of the dialyzer 1 of a dialyzing apparatus during dialysis, blood flows through the blood chamber 3 of the dialyzer 1 partitioned by a semipermeable film 2 into the blood chamber 3 and a dialyzate chamber 4, and dialyzate flows through the dialyzate chamber 4 at a predetermined flow rate. The method and apparatus are based on measuring dialysance or clearance at a predetermined dialyzate flow rate and/or blood flow rate, and then calculating dialysance or clearance at a certain dialyzate rate and blood flow rate.

3. 发明申请

WO0038761A3 METHOD FOR DETERMINING THE VOLUME OF DISTRIBUTION OF A BLOOD COMPONENT DURING A BLOOD TREATMENT, AND DEVICE 审中-公开
标题翻译：程序为确定血量目录物质分布血液处理和设备
公开(公告)号：WO0038761A3
公开(公告)日：2001-10-11
申请号：PCT/EP9910338
申请日：1999-12-23
申请人： FRESENIUS MEDICAL CARE DE GMBH , GOLDAU RAINER , GRAF THOMAS , GROSS MALTE
发明人： GOLDAU RAINER , GRAF THOMAS , GROSS MALTE
IPC分类号： A61B5/145 , A61B5/1459 , A61B5/1473 , A61M1/14 , A61M1/16
CPC分类号： A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1617 , A61M1/1635 , A61M1/3609 , A61M2205/3303 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2230/65
摘要： The invention relates to a method for determining the volume of distribution of a blood component in the body of a living organism, especially the volume of distribution of urea, during an extracorporeal blood treatment. According to this method, the blood to be treated flows through the blood chamber (3) of a dialysis machine (1) in an extracorporeal circuit, said dialysis machine being divided into said blood chamber and a dialysing liquid chamber (4) by a semipermeable membrane (2). Dialysing liquid flows through the dialysing liquid chamber of the dialysis machine in a dialysing liquid channel. The method is based on the determination of the temporal change in the concentration of the blood component in the blood upstream of the dialysis machine using the temporal variation in a physical or chemical characteristic of the dialysing liquid upstream and downstream of the dialysis machine and the determination of the volume of distribution of the substance in the body of a living organism using the temporal variation in the concentration of the blood component in the blood. The invention also relates to a device for the extracorporeal blood treatment, comprising a device for determining the volume of distribution of a blood component in the body of a living organism.
摘要翻译：它是用于确定在活体的主体中的血液成分的分布体积的方法，特别是尿素分布容积，体外血液处理，在其中在体外回路通过的血液腔（3）通过在半透膜（2）被处理血液中描述血液腔和透析（4）划分的透析器（1）流和透析流体流过透析液路径中的透析器的透析液腔。该方法是基于从透析液的物理或化学特性的时间变化上游，并且确定在血液透析器的下游和出的血液成分的浓度的该物质的分配的血液量的时间变化的透析器的上游侧的血液成分的浓度的时间变化在生命体的身体被确定。另外，对于与装置的体外血液处理用于确定血液成分的分布容积的装置将在生命体的身体进行说明。

4. 发明专利

CA2646042C CONTAINER FILLED WITH A LIQUID CONCENTRATE FOR MAKING DIALYSATE 未知
公开(公告)号：CA2646042C
公开(公告)日：2015-02-10
申请号：CA2646042
申请日：2007-06-01
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： GRAF THOMAS , LAFFAY PHILIPPE , DUMONT D AYOT FRANCOIS , LENGRAND PASCAL , THIBAULT BERTRAND , GASTAUER PAUL
IPC分类号： A61M1/16 , B65D75/00
摘要： The invention relates to the field of containers for providing liquid dialysate concentrates for a dialysis treatment of a patient with the aid of an artificial kidney. Up to now such concentrates have been delivered mainly in rigid plastic containers as the weight of the concentrate requires a certain stability of the container. Such containers also simplify the shipping of large loads as they can easily be arranged in layers on top of each other. These rigid containers have the disadvantage that because of their rigidity they are comparatively expensive as the container walls have to be thick enough leading to higher material expenses. Furthermore, the empty containers are bulky making the further processing cumbersome. The large amount of material to be recycled or discarded adds further to the cost. The invention avoids these drawbacks by proposing a container filled with a liquid dialysate concentrate that is a self- standing bag (1) made of flexible elastomeric sheets.

5. 发明专利

EA017416B1 КОНТЕЙНЕР, НАПОЛНЕННЫЙ ЖИДКИМ КОНЦЕНТРАТОМ ДЛЯ ПРИГОТОВЛЕНИЯ ДИАЛИЗАТА 未知
公开(公告)号：EA017416B1
公开(公告)日：2012-12-28
申请号：EA200802418
申请日：2007-06-01
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： GRAF THOMAS , GASTAUER PAUL , LAFFAY PHILIPPE , DUMONT D AYOT FRANCOIS , LENGRAND PASCAL , THIBAULT BERTRAND
IPC分类号： A61M1/16 , B65D75/00
摘要： Изобретениеотноситсяк областиконтейнеровдляобеспеченияконцентратовдиализнойжидкостидляпроцедурыдиализау пациентовдляискусственнойпочки. Досегодняшнегоднятакиеконцентратыпоставляютсяглавнымобразомв жесткихпластиковыхконтейнерах, посколькувесконцентрататребуетопределеннойустойчивостиконтейнера. Такиеконтейнерытакжеупрощаютотгрузкубольшихпартий, посколькуонилегкомогутбытьрасположеныслоямидругнадруге. Этижесткиеконтейнерыимеютнедостаток, посколькуиз-заихжесткостионисравнительнодорогие, таккакстенкаконтейнерадолжнабытьдостаточнотолстой, чтоприводитк болеевысокимзатратамматериала. Далее, пустыеконтейнерыявляютсягромоздкими, делаядальнейшуюобработкуобременительной. Большоеколичествоматериала, предназначенногодляпереработкииливыбрасывания, дополнительноувеличиваетстоимость. Изобретениеустраняетэтинедостатки, предлагаяконтейнер, заполненныйконцентратомдиализнойжидкости, которыйявляетсяустойчивыммешком (1), изготовленнымизгибкихэластомерныхлистов.

6. 发明专利

AT519512T 未知
公开(公告)号：AT519512T
公开(公告)日：2011-08-15
申请号：AT06011472
申请日：2006-06-02
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： DUMONT D AYOT FRANCOIS , GASTAUER PAUL , GRAF THOMAS , LAFFAY PHILIPPE , LENGRAND PASCAL , THIBAULT BERTRAND
IPC分类号： A61M1/16 , B65D75/00
摘要： The invention relates to the field of containers for providing liquid dialysate concentrates for a dialysis treatment of a patient with the aid of an artificial kidney. Up to now such concentrates have been delivered mainly in rigid plastic containers as the weight of the concentrate requires a certain stability of the container. Such containers also simplify the shipping of large loads as they can easily be arranged in layers on top of each other. These rigid containers have the disadvantage that because of their rigidity they are comparatively expensive as the container walls have to be thick enough leading to higher material expenses. Furthermore, the empty containers are bulky making the further processing cumbersome. The large amount of material to be recycled or discarded adds further to the cost. The invention avoids these drawbacks by proposing a container filled with a liquid dialysate concentrate that is a self-standing bag (1) made of flexible elastomeric sheets.

7. 发明专利

DE50214432D1 BEHÄLTER ENTHALTEND MINDESTENS ZWEI FESTSTOFFE UND DESSEN VERWENDUNG 未知
公开(公告)号：DE50214432D1
公开(公告)日：2010-06-24
申请号：DE50214432
申请日：2002-11-27
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： DUMONT D AYOT FRANCOIS , DUPLANIL STEPHANY , GRAF THOMAS , LAFFAY PHILIPPE , WILD THOMAS
IPC分类号： A61M1/16 , B65D77/08 , A61J1/00 , A61J1/03 , A61J1/10 , A61M1/14 , B65D81/20

8. 发明专利

HK1132171A1 CONNECTOR, CONTAINER WITH SUCH A CONNECTOR AND FLUID PREPARATION DEVICE WITH A MATING CONNECTOR FOR SUCH A CONTAINER 未知
公开(公告)号：HK1132171A1
公开(公告)日：2010-02-19
申请号：HK09110242
申请日：2009-11-04
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： BREHM WINFRIED , DUPIN THIERRY , EGGERT ILONA , FAULHABER THOMAS , GRAF THOMAS , LAFFAY PHILIPPE
IPC分类号： A61M20060101 , A61J1/05 , B65D33/14 , A61J1/10 , A61J1/16 , A61J1/20 , A61M1/14 , A61M1/16
摘要： The invention relates to the field of connectors for connecting a container with a fluid preparation device for preparing a fluid, in particular a container with a concentrate for the preparation of dialysis fluid. In order to simplify the handling during both the manufacturing process of such containers and the connection of such containers to the fluid preparation devices, the invention proposes a design of a connector (1) for connecting a first and second fluid line of the container with a third and fourth fluid line of the fluid preparation device with two lateraly spaced-apart mounting means (2, 4) which each incorporate one of two orifices (3, 5) terminating the first and second fluid lines. The invention also concerns a corresponding container and fluid preparation device.

9. 发明专利

DE50015400D1 未知
公开(公告)号：DE50015400D1
公开(公告)日：2008-11-27
申请号：DE50015400
申请日：2000-06-16
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： GRAF THOMAS , GROSS MALTE DR , GOLDAU RAINER , BARDORZ CHRISTOPH
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34 , B01D61/28 , B01D61/34

10. 发明专利

ES2278464T3 DISPOSITIVO PARA DETERMINAR EL VOLUMEN DE DISTRIBUCION DE UN COMPONENTE SANGUINEO DURANTE UN TRATAMIENTO EXTRACORPORAL DE LA SANGRE. 未知
公开(公告)号：ES2278464T3
公开(公告)日：2007-08-01
申请号：ES99964666
申请日：1999-12-23
申请人： FRESENIUS MEDICAL CARE DE GMBH
发明人： GOLDAU RAINER , GRAF THOMAS , GROSS MALTE
IPC分类号： A61B5/145 , A61M1/36 , A61B5/1459 , A61B5/1473 , A61M1/14 , A61M1/16
摘要： Dispositivo para determinar el volumen de distribución de un componente sanguíneo en el organismo de un ser vivo durante un tratamiento extracorporal de la sangre realizado con un dispositivo de tratamiento extracorporal de la sangre, en el que la sangre que ha de tratarse fluye en un circuito extracorporal a través de la cámara (3) sanguínea de un dializador (1) dividido mediante una membrana (2) semipermeable en la cámara sanguínea y una cámara (4) de líquido dializante y el líquido dializante fluye en un trayecto de líquido dializante a través de la cámara de líquido dializante del dializador, con un dispositivo (17) para modificar la concentración (cdi) del componente sanguíneo en el líquido dializante en el trayecto de líquido dializante agua arriba del dializador un dispositivo (24) de medición para detectar la concentración (cdo) de la sustancia en el líquido dializante en el trayecto del líquido dializante aguas abajo del dializador una unidad (29) de cálculo y de análisis, configurada de tal manera que, a partir de una modificación de la concentración del componente sanguíneo en el líquido dializante en el trayecto del líquido dializante aguas abajo del dializador, que se atribuye a la modificación de la concentración del componente sanguíneo en la sangre debido a una modificación de la concentración de la sustancia en el líquido dializante aguas arriba del dializador, puede determinarse el volumen V de distribución del componente sanguíneo, caracterizado porque la unidad (29) de cálculo y de análisis se configura adicionalmente de tal manera que la unidad de cálculo y de análisis tiene en cuenta una modificación de la concentración del componente sanguíneo en el líquido dializante aguas arriba del dializador (1) generada por el dispositivo (17) para la modificación de la concentración de la sustancia, aumentando súbitamente la concentración de la sustancia desde un valor inicial hasta un valor predeterminado y reduciéndola luego súbitamente hasta un valor predeterminado, tras lo cual vuelve a ajustarse el valor inicial.

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