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1. 发明申请

WO2013067543A1 METHODS AND COMPOSITIONS FOR ADMINISTERING A SPECIFIC WAVELENGTH PHOTOTHERAPY 审中-公开
标题翻译：用于管理特定波长摄影的方法和组合
公开(公告)号：WO2013067543A1
公开(公告)日：2013-05-10
申请号：PCT/US2012/063628
申请日：2012-11-05
申请人： FOLLEA INTERNATIONAL LTD. , GOREN, Andy Ofer , MCCOY, John
发明人： GOREN, Andy Ofer , MCCOY, John
IPC分类号： A61N5/00 , A61N5/06 , A61N1/30 , A61M37/00 , A61K8/30
CPC分类号： A61K8/602 , A61K8/40 , A61K31/24 , A61K31/353 , A61K31/7034 , A61K31/7048 , A61K2800/81 , A61N5/0616 , A61N5/062 , A61N2005/0628 , A61N2005/0655 , A61N2005/0657 , A61N2005/0661 , A61N2005/0667 , A61Q5/00 , A61Q17/04 , B01J19/12
摘要： Methods and compositions are disclosed for administering electromagnetic radiation (EMR), for therapeutic or cosmetic purposes, or for purposes of curing a polymeric material.
摘要翻译：公开了用于施用用于治疗或化妆目的的电磁辐射（EMR）或为了固化聚合物材料的目的的方法和组合物。

2. 发明申请

WO2014070266A1 COMPOSITIONS FOR ADMINISTERING A SPECIFIC WAVELENGTH PHOTOTHERAPY 审中-公开
标题翻译：用于管理特定波长光合作用的组合物
公开(公告)号：WO2014070266A1
公开(公告)日：2014-05-08
申请号：PCT/US2013/051721
申请日：2013-07-23
申请人： GLOBAL LIFE SCIENCE PARTNERS LIMITED , GOREN, Andy Ofer , MCCOY, John
发明人： GOREN, Andy Ofer , MCCOY, John
IPC分类号： A61N5/06 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/498 , A61K2800/434 , A61K2800/81 , A61N5/0616 , A61N2005/0667
摘要： Methods are disclosed for administering electromagnetic radiation (EMR), which may include filtering EMR from part of the EMR spectrum while allowing passage of EMR at a desired wavelength. A fluorescent component may be included, which absorbs EMR at one wavelength and emits EMR at the desired wavelength. Uses may include the treatment of acne. Pruritus may also be treated by allowing the passage to the skin of a particular UV wavelength from sunlight, which has an immunosuppressive effect, while protecting the skin from other harmful UV radiation.
摘要翻译：公开了用于施用电磁辐射（EMR）的方法，其可以包括从部分EMR光谱过滤EMR，同时允许以期望波长的EMR通过。可以包括荧光成分，其吸收一个波长的EMR并以期望的波长发射EMR。用途可能包括治疗痤疮。也可以通过使具有免疫抑制作用的太阳光通过特定紫外线波长的皮肤，同时保护皮肤免受其他有害紫外线辐射的影响来治疗瘙痒。

3. 发明申请

WO2013056264A2 SYSTEMS AND METHODS FOR PREDICTING RESPONSE TO ANTI-ANDROGEN THERAPY FOR THE TREATMENT OF ANDROGENETIC ALOPECIA 审中-公开
标题翻译：用于预防针对治疗原发性ALOPECIA的安哥拉治疗的反应的系统和方法
公开(公告)号：WO2013056264A2
公开(公告)日：2013-04-18
申请号：PCT/US2012/060321
申请日：2012-10-15
申请人： FOLLEA INTERNATIONAL LIMITED , GOREN, Andy Ofer , MCCOY, John
发明人： GOREN, Andy Ofer , MCCOY, John
IPC分类号： A61K31/565 , A61K31/568 , A61K48/00 , A61P17/14
CPC分类号： A61K31/568 , G01N33/743 , G01N2800/20 , G01N2800/52

4. 发明申请

WO2015122891A1 RETRACTABLE INTELLIGENT REFLECTOR SYSTEM 审中-公开
标题翻译：可回收的智能反射器系统
公开(公告)号：WO2015122891A1
公开(公告)日：2015-08-20
申请号：PCT/US2014/016120
申请日：2014-02-12
申请人： GOREN, Andy , GOREN, Yehuda , HAFID, Daniel , MCCOY, John
发明人： GOREN, Andy , GOREN, Yehuda , HAFID, Daniel , MCCOY, John
IPC分类号： F24J2/10
CPC分类号： F24S23/77 , F24S20/50 , F24S23/74 , F24S23/745 , F24S23/81 , F24S30/20 , F24S50/20 , Y02E10/45 , Y02E10/47
摘要： A retractable intelligent reflector system for directing light onto a solar device includes one or more movable reflectors operable to direct light at the solar device, a support structure for supporting the one or more movable reflectors, at least one motor for motivating the one or more movable reflectors, and a controller for issuing actuation signals to the motor as a function of one or environmental conditions. The solar device can be a photovoltaic cell array, or a solar water heater. The environmental conditions can include at least one of time of day, calendar date, season, location, latitude, temperature, wind speed, wind direction, strain, and light conditions.
摘要翻译：用于将光引导到太阳能装置上的可伸缩智能反射器系统包括一个或多个可操作以将太阳能装置引导光的可移动反射器，用于支撑一个或多个可移动反射器的支撑结构，用于激励一个或多个可移动反射器的至少一个电动机反射器和用于根据一个或环境条件向电动机发出致动信号的控制器。太阳能装置可以是光伏电池阵列或太阳能热水器。环境条件可以包括时间，日历日期，季节，位置，纬度，温度，风速，风向，应变和光照条件中的至少一个。

5. 发明申请

WO2007064882A2 TREATMENT OF CONDITIONS INVOLVING DEMYELINATION 审中-公开
标题翻译：治疗涉及血色素沉着的病症
公开(公告)号：WO2007064882A2
公开(公告)日：2007-06-07
申请号：PCT/US2006/045993
申请日：2006-12-01
申请人： BIOGEN IDEC MA INC. , MI, Sha , PEPINSKY, R., Blake , MCCOY, John
发明人： MI, Sha , PEPINSKY, R., Blake , MCCOY, John
IPC分类号： A61K39/395
CPC分类号： C07K16/28 , A01K67/0275 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0393 , A61K2039/505 , C07K14/4702 , C07K16/18 , C07K16/2863 , C07K16/32 , C07K16/40 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C12N15/8509
摘要： The invention provides methods of treating diseases, disorders or injuries involving demyelination and dysmyelination, including multiple sclerosis, by the administration of an Sp35 antagonist. Additional methods include methods for inhibiting the binding of the Sp35 polypeptide with the ErbB2 polypeptide and a method for increasing ErbB2 phosphorylation by contacting oligodendrocytes with an effective amount of a composition comprising an Sp35 antagonist of the invention. Further embodiments of the invention include methods of inhibiting the binding of the Sp35 polypeptide with the ErbB2, increasing ErbB2 phosphorylation and promoting oligodendrocyte differentiation comprising contacting oligodendrocyte or oligodendrcoyte progenitor cells with an ErbB2 binding agent.
摘要翻译：本发明提供了通过施用Sp35拮抗剂治疗涉及脱髓鞘和髓鞘形成障碍包括多发性硬化的疾病，障碍或损伤的方法。另外的方法包括抑制Sp35多肽与ErbB2多肽结合的方法和通过使少突胶质细胞与有效量的包含本发明的Sp35拮抗剂的组合物接触来增加ErbB2磷酸化的方法。本发明进一步的实施方案包括抑制Sp35多肽与ErbB2的结合，增加ErbB2磷酸化和促进少突胶质细胞分化的方法，包括使少突胶质细胞或少突胶质祖细胞与ErbB2结合剂接触。

6. 发明申请

WO2018093369A1 TREATMENT OF SEXUAL DYSFUNCTION AND FOR IMPROVED SEXUAL QUALITY OF LIFE 审中-公开
公开(公告)号：WO2018093369A1
公开(公告)日：2018-05-24
申请号：PCT/US2016/062547
申请日：2016-11-17
申请人： GOREN, Ofer A. , MCCOY, John
发明人： GOREN, Ofer A. , MCCOY, John
IPC分类号： A61P15/00 , A61P15/02 , A61K31/221 , A61K31/341 , A61K31/4164 , A61K31/4178 , A61K31/465 , A62D101/02
CPC分类号： A61P15/00 , A61K31/137 , A61K31/166 , A61K31/221 , A61K31/27 , A61K31/4174 , A61K31/4178 , A61K31/439 , A61K31/445 , A61K31/465 , A61P15/02
摘要： Compositions and methods for treating sexual dysfunction and enhancing sexual satisfaction using topical application of alpha-1 adrenergic receptor agonists, muscarinic acetylcholine receptor agonists, nicotinic acetylcholine receptor agonists, and cholinesterase inhibitors are disclosed.

7. 发明申请

WO2006002437A3 TREATMENT OF CONDITIONS INVOLVING DEMYELINATION 审中-公开
公开(公告)号：WO2006002437A3
公开(公告)日：2006-01-05
申请号：PCT/US2005/022881
申请日：2005-06-24
申请人： BIOGEN IDEC MA INC. , MI, Sha , PEPINSKY, R. Blake , MCCOY, John
发明人： MI, Sha , PEPINSKY, R. Blake , MCCOY, John
IPC分类号： A61K38/17 , A61K39/00 , A61K31/7088
摘要： The invention provides methods of treating diseases, disorsers or injuries involving demyelination and dysmyelination, including multiple sclerosis, by the administration of an Sp35 antagonist.

8. 发明申请

WO2016077744A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA 审中-公开
标题翻译：用于预防ALOPECIA的系统和方法
公开(公告)号：WO2016077744A1
公开(公告)日：2016-05-19
申请号：PCT/US2015/060663
申请日：2015-11-13
申请人： GOREN, Ofer A. , MCCOY, John
发明人： GOREN, Ofer A. , MCCOY, John
IPC分类号： A61K31/137
CPC分类号： A61K8/41 , A61K8/9789 , A61K9/0014 , A61K9/08 , A61K31/137 , A61K31/4174 , A61K36/752 , A61Q7/00
摘要： Traction alopecia and other disorders related to mechanical pulling on hair are treated or prevented by administering a topical composition comprising an alpha-1 adrenergic receptor agonist or another compound or electrical stimulation to contract the arrector pili muscle. Compositions and methods are disclosed herein for the treatment and prevention of hair loss disorders caused at least in part by repeated application of tensile force to hair, including, without limitation, traction alopecia. Such disorders may be treated or prevented by the application to the hair follicle or scalp of a compound or agent that induces contraction of the arrector pili (AP) muscle, such as, without limitation, alpha 1 adrenergic receptor agonists (AIAR agonists).
摘要翻译：通过施用包含α-1肾上腺素能受体激动剂或其他化合物或电刺激的局部组合物来收缩牵引器皮下肌肉来治疗或预防牵引性脱发和与机械牵拉毛发有关的其它障碍。本文公开的组合物和方法用于治疗和预防至少部分地通过对头发反复施加张力而引起的脱发障碍，包括但不限于牵引脱发。可以通过应用于诱导放射性刺激（AP）肌肉（例如但不限于α1肾上腺素能受体激动剂（AIAR激动剂））的收缩的化合物或药剂的毛囊或头皮来治疗或预防这些疾病。

9. 发明申请

WO2009061500A1 USE OF LINGO-4 ANTAGONISTS IN THE TREATMENT OF CONDITIONS INVOLVING DEMYELINATION 审中-公开
标题翻译：使用LINGO-4拮抗剂治疗涉及染色的病症
公开(公告)号：WO2009061500A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/012620
申请日：2008-11-10
申请人： BIOGEN IDEC MA INC. , MI, Sha , PEPINSKY, R., Blake , MCCOY, John
发明人： MI, Sha , PEPINSKY, R., Blake , MCCOY, John
IPC分类号： C12N5/00 , A01N37/18 , A61K31/70
CPC分类号： A61K38/1709 , A61K31/70 , A61K38/00 , A61K39/3955 , A61K48/00 , C07K14/47 , C07K14/70503 , C07K16/18 , C07K2317/76 , C07K2319/30 , C12N5/0622 , C12N2501/998 , C12N2502/08 , Y02A50/406
摘要： The invention provides methods of treating diseases, disorsers or injuries involving demyelination and dysmyelination, including multiple sclerosis, by the administration of a LINGO-4 antagonist.
摘要翻译：本发明提供了通过施用LINGO-4拮抗剂治疗涉及脱髓鞘和脱髓鞘疾病（包括多发性硬化）的疾病，脱发剂或损伤的方法。

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