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1. 发明授权

US4391805A 1-(1,3-Dioxolan-2-ylmethyl)-azoles, their salts and their use 失效
标题翻译： 1-（1,3-二氧戊环-2-基甲基） - 唑，它们的盐及其用途
公开(公告)号：US4391805A
公开(公告)日：1983-07-05
申请号：US311184
申请日：1981-10-14
申请人： Ernst Blume , Wolfgang Schaper , Wolfgang Raether , Walter Dittmar
发明人： Ernst Blume , Wolfgang Schaper , Wolfgang Raether , Walter Dittmar
IPC分类号： C07D217/04 , C07D233/60 , C07D295/096 , C07D295/185 , C07D295/26 , C07D317/20 , C07D317/22 , C07D317/24 , C07D333/28 , C07D521/00 , A61K31/415 , C07D405/06
CPC分类号： C07D295/185 , C07D217/04 , C07D231/12 , C07D233/56 , C07D249/08 , C07D295/096 , C07D295/26 , C07D317/20 , C07D317/22 , C07D317/24 , C07D333/28
摘要： 1-(1,3-Dioxolan-2-ylmethyl)-azoles of the general formula ##STR1## and their stereoisomers and their salts with physiologically acceptable acids, the preparation of these compounds, pharmaceutical formulations containing the latter and their use against mycoses, protozoa and Gram-positive and Gram-negative bacteria are described.
摘要翻译：具有通式“IMAGE”的1-（1,3-二氧戊环-2-基甲基） - 唑及其立体异构体及其与生理上可接受的酸的盐，这些化合物的制备，含有后者的药物制剂及其用于治疗真菌病，描述了原生动物和革兰氏阳性和革兰氏阴性细菌。

2. 发明授权

US4870088A 1-[1-aryl-1-hydroxy-2-azolyl-ethyl]-1-aryl-cyclopropane derivatives, and their fungicidal use thereof 失效
标题翻译： 1- [1-芳基-1-羟基-2-唑基 - 乙基] -1-芳基 - 环丙烷衍生物及其杀真菌用途
公开(公告)号：US4870088A
公开(公告)日：1989-09-26
申请号：US25621
申请日：1987-03-13
申请人： Ernst Blume , Wolfgang Schaper , Heinz Ehrhardt , Wolfgang Raether , Walter Dittmar , Heinz Hanel , Burkhard Sachse
发明人： Ernst Blume , Wolfgang Schaper , Heinz Ehrhardt , Wolfgang Raether , Walter Dittmar , Heinz Hanel , Burkhard Sachse
IPC分类号： C07D247/00 , A01N43/50 , A01N43/653 , C07C41/00 , C07C43/18 , C07C67/00 , C07C201/00 , C07C213/00 , C07C215/42 , C07C217/48 , C07C217/74 , C07C253/00 , C07C255/54 , C07C313/00 , C07C317/12 , C07C317/14 , C07C317/18 , C07C317/20 , C07C323/22 , C07D233/56 , C07D233/60 , C07D233/61 , C07D249/08 , C07D307/38 , C07D333/00 , C07D401/12 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/12 , C07D409/14 , C07D417/12 , C07D521/00
CPC分类号： C07D231/12 , A01N43/653 , C07D233/56 , C07D249/08
摘要： Compounds I ##STR1## where A equals t-butyl or a large number of (substituted) aromatics; Y equals azolyl; or Y equals --X--R.sup.1 where X=oxygen or sulfur and R.sup.1 equals (cyclo)alkyl or (heterocyclic) aryl; or Y equals ##STR2## where R.sup.2 equals (cyclo)alkyl, acetyl or aryl; or Y equals --NR.sup.3 R.sup.4 where R.sup.3 /R.sup.4 is alkyl; or Y equals several nitrogen-containing heterocyclic rings; Z equals OH, alkylcarbonyloxy, hal, alkoxy or benzyloxy; and the salts thereof are effective antimycotics or fungicides.They are obtained by reaction of II ##STR3## with (CH.sub.3).sub.2 ##STR4## and further reaction of the compound IV ##STR5## obtained from this with a nucleophile YM (M=hydrogen or a metal equivalent).The compounds I (where Z=OH) resulting from this can be acylated or alkylated, or converted into I where Z=hal.
摘要翻译：其中A等于叔丁基或大量（取代的）芳族化合物; Y等于唑基; 或Y表示-X-R1，其中X =氧或硫，R1表示（环）烷基或（杂环）芳基; 或Y等于，其中R2等于（环）烷基，乙酰基或芳基; 或Y为-NR 3 R 4，其中R 3 / R 4为烷基; 或Y等于若干含氮杂环; Z为OH，烷基羰基氧基，卤素，烷氧基或苄氧基; 其盐是有效的抗真菌剂或杀真菌剂。它们通过II（II）与（CH 3）2图像III的反应和从其获得的化合物IV＆lt; IMAGE＆gt;与亲核试剂YM（M =氢或金属当量）的反应获得。由此产生的化合物I（其中Z = OH）可以被酰化或烷基化，或转化为I，其中Z = hal。

3. 发明授权

US4717724A 1-(1,3-dioxolan-2-ylmethyl)azoles, their salts and their use 失效
标题翻译： 1-（1,3-二氧戊环-2-基甲基）唑，它们的盐及其用途
公开(公告)号：US4717724A
公开(公告)日：1988-01-05
申请号：US587585
申请日：1984-03-08
申请人： Wolfgang Schaper , Ernst Blume , Wolfgang Raether , Walter Dittmar
发明人： Wolfgang Schaper , Ernst Blume , Wolfgang Raether , Walter Dittmar
IPC分类号： A61K31/47 , A61K31/472 , A61P31/04 , A61P33/02 , C07D217/04 , C07D217/06 , C07D217/10 , C07D217/14 , C07D217/16 , C07D217/18 , C07D221/02 , C07D221/20 , C07D401/06 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D471/10 , C07D491/10 , C07D491/107 , C07D495/10 , C07D521/00 , C07D401/14
CPC分类号： C07D221/20 , C07D217/04 , C07D217/06 , C07D217/10 , C07D217/14 , C07D217/16 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/04 , C07D409/06 , C07D471/10 , C07D491/10 , C07D495/10
摘要： New 1-(1,3-dioxolan-2-ylmethyl)azoles, their stereoisomers and their salts are described, as are processes for their preparation. The new compounds are chemotherapeutic agents. They are active against skin fungi, mold fungi and yeasts and against bacteria.
摘要翻译：描述了新的1-（1,3-二氧戊环-2-基甲基）唑，它们的立体异构体及其盐，以及它们的制备方法。新化合物是化学治疗剂。它们对皮肤真菌，霉菌，酵母和细菌都有活性。

4. 发明授权

US4829075A Antimycotic 1,1-disubstituted cyclopropane derivatives 失效
标题翻译：抗真菌剂1,1-二取代环丙烷衍生物
公开(公告)号：US4829075A
公开(公告)日：1989-05-09
申请号：US25581
申请日：1987-03-13
申请人： Heinz Ehrhardt , Ernst Blume , Wolfgang Raether , Walter Dittmar
发明人： Heinz Ehrhardt , Ernst Blume , Wolfgang Raether , Walter Dittmar
IPC分类号： C07C41/00 , A01N43/50 , A01N43/653 , A61K31/12 , A61K31/13 , A61K31/41 , A61K31/495 , C07C49/175 , C07C49/84 , C07C67/00 , C07C201/00 , C07C205/59 , C07C213/00 , C07D213/70 , C07D233/56 , C07D233/60 , C07D239/38 , C07D249/08 , C07D295/10 , C07D295/116 , C07D307/38 , C07D333/28 , C07D401/14 , C07D403/06 , C07D405/06 , C07D409/06 , C07D521/00
CPC分类号： C07D213/70 , C07C205/59 , C07C317/00 , C07C321/00 , C07C323/00 , C07C49/175 , C07C49/84 , C07D231/12 , C07D233/56 , C07D239/38 , C07D249/08 , C07D295/116 , C07D307/38 , C07D333/28
摘要： Compounds I ##STR1## where A equals t-butyl, phenyl, biphenylyl, phenoxyphenyl, benzylphenyl, benzyloxyphenyl, phenylthiophenyl, phenylsulfinylphenyl, phenylsulfonylphenyl, naphthyl, 1,2,3,4-tetrahydronaphthyl, indanyl, fluorenyl, thienyl, furyl, pyridyl, isoxazolyl, pyrazolyl, benzofuryl or benzothienyl,Z equals CO, CH.sub.2 or radicals of ketone derivatives;Y equals azole or equals --X--R.sup.8 (R.sup.8 =(cyclo)alkyl or an aromatic) or equals a number of amine derivatives or equal acyl,are antimycotics. The preparation and use as medicaments are described.
摘要翻译：化合物Ⅰ其中A等于叔丁基，苯基，联苯基，苯氧基苯基，苄基苯基，苄氧基苯基，苯硫基苯基，苯基亚磺酰基苯基，苯基磺酰基苯基，萘基，1,2,3,4-四氢萘基，茚满基，芴基，噻吩基，呋喃基，吡啶基，异恶唑基，吡唑基，苯并呋喃基或苯并噻吩基，Z表示CO，CH2或酮衍生物的自由基; Y等于唑或等于-X-R8（R8 =（环）烷基或芳族）或等于多个胺衍生物或等同酰基，为抗真菌剂。描述了作为药物的制备和用途。

5. 发明申请

US20150008197A1 System For Holding In-Line Two Wheeled Vehicles 审中-公开
标题翻译：用于保持在线两轮车辆的系统
公开(公告)号：US20150008197A1
公开(公告)日：2015-01-08
申请号：US13934326
申请日：2013-07-03
申请人： Ernst Blume
发明人： Ernst Blume
IPC分类号： B62H3/08
CPC分类号： B62H3/08 , B62H3/04
摘要： The system for holding a number of in-line two wheeled vehicles has a vertical support column. A lifting bracket has an end that engages a vertical channel of the vertical support. A counter balance system in the vertical support column is connected to the lifting bracket. A horizontal track runs perpendicular to a face of the vertical support column with the vertical channel. A horizontal bracket engages the horizontal track. A bike or other two wheel vehicle is held by the lifting bracket. Because the lifting bracket has a counter balance system a person can easily lift the bike up in the air. The horizontal bracket can also hold a bike. A bike on the horizontal bracket can be slid so that it is under the lifting bracket, which may be holding a second bike.
摘要翻译：用于保持多个在线两轮车的系统具有垂直支撑柱。提升支架具有接合垂直支撑件的垂直通道的端部。垂直支撑柱中的平衡系统连接到提升支架。水平轨道垂直于垂直支撑柱的垂直通道。水平支架接合水平轨道。自行车或其他两轮车辆由提升支架保持。因为提升支架具有平衡系统，所以人们可以轻松地将自行车升起在空中。水平支架也可以搭载自行车。水平支架上的自行车可以滑动，使其位于起重支架下方，可能会放置第二辆自行车。

6. 发明授权

US4431813A Process for the preparation of 2-mercaptobenzothiazoles 失效
标题翻译： 2-巯基苯并噻唑的制备方法
公开(公告)号：US4431813A
公开(公告)日：1984-02-14
申请号：US239445
申请日：1981-03-02
申请人： Reinhard Handte , Lothar Willms , Ernst Blume
发明人： Reinhard Handte , Lothar Willms , Ernst Blume
IPC分类号： C07D277/72
CPC分类号： C07D277/72
摘要： The preparation of (optionally substituted) 2-mercaptobenzothiazole by reaction of corresponding 2-halogenoanilines with an alkali metal xanthate or alkaline earth metal xanthate or with CS.sub.2 in the presence of bases.
摘要翻译：通过相应的2-卤代苯胺与碱金属黄原酸盐或碱土金属黄原酸盐或与CS2在碱存在下反应制备（任选取代的）2-巯基苯并噻唑。

7. 发明授权

US09278721B2 System for holding in-line two wheeled vehicles 有权
标题翻译：保持在线二轮车的系统
公开(公告)号：US09278721B2
公开(公告)日：2016-03-08
申请号：US13934326
申请日：2013-07-03
申请人： Ernst Blume
发明人： Ernst Blume
IPC分类号： B62H3/08 , B62H3/04
CPC分类号： B62H3/08 , B62H3/04
摘要： The system for holding a number of in-line two wheeled vehicles has a vertical support column. A lifting bracket has an end that engages a vertical channel of the vertical support. A counter balance system in the vertical support column is connected to the lifting bracket. A horizontal track runs perpendicular to a face of the vertical support column with the vertical channel. A horizontal bracket engages the horizontal track. A bike or other two wheel vehicle is held by the lifting bracket. Because the lifting bracket has a counter balance system a person can easily lift the bike up in the air. The horizontal bracket can also hold a bike. A bike on the horizontal bracket can be slid so that it is under the lifting bracket, which may be holding a second bike.
摘要翻译：用于保持多个在线两轮车的系统具有垂直支撑柱。提升支架具有接合垂直支撑件的垂直通道的端部。垂直支撑柱中的平衡系统连接到提升支架。水平轨道垂直于垂直支撑柱的垂直通道。水平支架接合水平轨道。自行车或其他两轮车辆由提升支架保持。因为提升支架具有平衡系统，所以人们可以轻松地将自行车升起在空中。水平支架也可以搭载自行车。水平支架上的自行车可以滑动，使其位于起重支架下方，可能会放置第二辆自行车。

8. 发明授权

US07472517B2 Bilevel bicycle storage system 有权
标题翻译：双层自行车存放系统
公开(公告)号：US07472517B2
公开(公告)日：2009-01-06
申请号：US11001935
申请日：2004-12-02
申请人： Ernst Blume
发明人： Ernst Blume
IPC分类号： E04H1/00 , E04H3/00 , E04H5/00 , E04H6/00
CPC分类号： E04H6/005 , B62H3/00 , B62H3/04 , Y10S52/14 , Y10T70/5872
摘要： A multiple-level bicycle storing system includes a framework with a vertical support and a mounting frame defining upper and lower storing spaces. Each storing space includes a receiver to hold a bicycle. The upper receiver has a distal end, a proximal end and a U-shaped channel along the top surface. The upper receiver is pivotally attached to the mounting frame, enabling the upper receiver to tilt from horizontal to a loading and unloading position. The proximal end of the upper receiver is located near the floor when pivoted into the loading and unloading position. The upper receiver pivots up from the loading and unloading position into the horizontal storage position. The bicycles and the storing spaces are enclosed, and a floor separates the lower storing space from the upper storing space. Each storing space includes a lockable door and conceals the pivot point, upper receiver and bicycles inside the enclosure.
摘要翻译：多级自行车存储系统包括具有垂直支撑的框架和限定上部和下部存储空间的安装框架。每个存储空间包括用于保持自行车的接收器。上部接收器具有远端，近端和沿着顶表面的U形通道。上接收器枢转地附接到安装框架，使得上接收器能够从水平倾斜到装载和卸载位置。当枢转到装载和卸载位置时，上部接收器的近端位于地板附近。上部接收器从装载和卸载位置枢转到水平存储位置。自行车和存放空间被封闭，并且地板将下存储空间与上储存空间分开。每个存放空间包括一个可锁定的门，并且在该外壳内隐藏枢转点，上部接收器和自行车。

9. 发明申请

US20070107322A1 Bilevel bicycle storage system 失效
标题翻译：双层自行车存放系统
公开(公告)号：US20070107322A1
公开(公告)日：2007-05-17
申请号：US11646005
申请日：2006-12-27
申请人： Ernst Blume
发明人： Ernst Blume
IPC分类号： E04H14/00
CPC分类号： B62H3/12 , B62H3/04 , B62H3/08 , E04H6/005
摘要： A multiple-level bicycle storing system includes a framework having a vertical support and a horizontal mounting frame. The framework defines a lower storing space with a lower receiver, a middle storing space with an upper receiver attached to the mounting frame with a pivot mechanism, and an upper storing space. The upper storing space includes an upper track having a horizontal rail, a shuttle movably engaging the rail, an electric shuttle motor attached to the rail and the shuttle and a power source, a cable winch incorporated into the shuttle, an electric winch motor attached to the cable winch and the power source, a control box attached between the winch motor, the shuttle motor and the power source, and a bicycle support attached to the cable winch. The pivot mechanism includes a pluraility of rollers, rails, a lever and a gas spring to enable extension of the upper receiver.
摘要翻译：多级自行车存放系统包括具有垂直支撑件和水平安装框架的框架。框架限定了具有下部接收器的较低的存储空间，具有上部接收器的中间存储空间，其具有通过枢转机构连接到安装框架和上部存储空间。上存储空间包括具有水平导轨的上轨道，可移动地接合轨道的梭子，附接到轨道和梭子的电动飞梭马达和动力源，并入梭子的电缆绞盘，附接到电缆绞盘和电源，连接在绞盘马达，往复马达和动力源之间的控制箱，以及连接到缆绳绞盘的自行车支架。枢转机构包括多个辊，导轨，杠杆和气弹簧，以使上部接收器能够延伸。

10. 发明授权

US07481027B2 Bilevel bicycle storage system 失效
标题翻译：双层自行车存放系统
公开(公告)号：US07481027B2
公开(公告)日：2009-01-27
申请号：US11646005
申请日：2006-12-27
申请人： Ernst Blume
发明人： Ernst Blume
IPC分类号： E04H1/00 , E04H3/00 , E04H5/00 , E04H6/00 , E04H9/00 , E04H14/00 , A47F7/00
CPC分类号： B62H3/12 , B62H3/04 , B62H3/08 , E04H6/005
摘要： A multiple-level bicycle storing system includes a framework having a vertical support and a horizontal mounting frame. The framework defines a lower storing space with a lower receiver, a middle storing space with an upper receiver attached to the mounting frame with a pivot mechanism, and an upper storing space. The upper storing space includes an upper track having a horizontal rail, a shuttle movably engaging the rail, an electric shuttle motor attached to the rail and the shuttle and a power source, a cable winch incorporated into the shuttle, an electric winch motor attached to the cable winch and the power source, a control box attached between the winch motor, the shuttle motor and the power source, and a bicycle support attached to the cable winch. The pivot mechanism includes a plurality of rollers, rails, a lever and a gas spring to enable extension of the upper receiver.
摘要翻译：多级自行车存放系统包括具有垂直支撑件和水平安装框架的框架。框架限定了具有下部接收器的较低的存储空间，具有上部接收器的中间存储空间，其具有通过枢转机构连接到安装框架和上部存储空间。上存储空间包括具有水平导轨的上轨道，可移动地接合轨道的梭子，附接到轨道和梭子的电动飞梭马达和动力源，并入梭子的电缆绞盘，附接到电缆绞盘和电源，连接在绞盘马达，往复马达和动力源之间的控制箱，以及连接到缆绳绞盘的自行车支架。枢转机构包括多个辊子，轨道，杠杆和气体弹簧，以能够延伸上部接收器。

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