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1. 发明授权

US06238342B1 Ultrasonic tissue-type classification and imaging methods and apparatus 有权
标题翻译：超声组织型分类及成像方法及装置
公开(公告)号：US06238342B1
公开(公告)日：2001-05-29
申请号：US09318892
申请日：1999-05-26
申请人： Ernest Joseph Feleppa , Frederic Louis Lizzi , Tian Liu
发明人： Ernest Joseph Feleppa , Frederic Louis Lizzi , Tian Liu
IPC分类号： A61B800
CPC分类号： A61B17/3403 , A61B8/00 , A61B8/08 , A61B2017/00274 , A61B2018/00547 , G01S7/52036 , G01S7/52084 , G06F19/00
摘要： Clinical data, ultrasonic radio frequency (RF) backscatter spectral data and histological results of corresponding biopsy sites are stored in a database and are used to train a classifier suitable for real-time tissue classification and imaging. In clinical use, clinical data and ultrasonic RF backscatter data are applied as input variables to the trained classifier which assigns a likelihood of cancer (LOC) score to each pixel location in an ultrasound image. The LOC scores are then categorized by ranges, which can be established by user selected threshold values, to apply different colors or grey scale values distinguishing varying levels of suspicion (LOS) to each pixel position in real-time. This classification and display technique is especially valuable for guiding a person performing a needle biopsy of the prostate.
摘要翻译：临床数据，超声波射频（RF）反向散射光谱数据和相应活检部位的组织学结果存储在数据库中，用于训练适合实时组织分类和成像的分类器。在临床应用中，将临床数据和超声波反向散射数据作为输入变量应用于经训练的分类器，其将超声图像中的每个像素位置分配癌症（LOC）得分的可能性。然后根据用户选择的阈值来确定LOC分数，以便将不同的颜色或灰度值实时地区分为各种像素位置（LOS）。这种分类和显示技术对于指导进行前列腺的针活检的人是特别有价值的。

2. 发明授权

US09502187B2 Method for controlling a current-interrupting device in a high-voltage electrical network 有权
标题翻译：用于控制高压电网中的电流中断装置的方法
公开(公告)号：US09502187B2
公开(公告)日：2016-11-22
申请号：US14115338
申请日：2012-04-30
申请人： Thierry Jung , Tian Liu , Houria Siguerdidjane , Marc Petit
发明人： Thierry Jung , Tian Liu , Houria Siguerdidjane , Marc Petit
IPC分类号： H01H7/16 , H02H3/02 , H02H7/04
CPC分类号： H01H7/16 , H02H3/021 , H02H7/04
摘要： The invention relates to a method of controlling switchgear in order to estimate the remanent flux value of a power transformer during disconnection from a high-voltage electrical network using voltage measurements delivered by a capacitive voltage transformer by correcting the transfer function of the capacitive voltage transformer, and in which said value is delivered to a controller that determines the optimum switchgear switching instant.
摘要翻译：本发明涉及一种控制开关设备的方法，以便通过校正电容式电压互感器的传递函数，通过电容式电压互感器提供的电压测量来估计断开与高压电网之间的电力变压器的剩余通量值，并且其中所述值被传送到确定最佳开关设备切换瞬间的控制器。

3. 发明授权

US09448289B2 Background field removal method for MRI using projection onto dipole fields 有权
标题翻译：使用投影到偶极场上的MRI的背景场去除方法
公开(公告)号：US09448289B2
公开(公告)日：2016-09-20
申请号：US13304141
申请日：2011-11-23
申请人： Yi Wang , Ludovic de Rochefort , Tian Liu , Ildar Khalidov
发明人： Yi Wang , Ludovic de Rochefort , Tian Liu , Ildar Khalidov
IPC分类号： G06K9/00 , G01R33/24 , G01R33/56
CPC分类号： G01R33/24 , G01R33/5608 , G06T2207/10088
摘要： For optimal image quality in susceptibility-weighted imaging and accurate quantification of susceptibility, it is necessary to isolate the local field generated by local magnetic sources (such as iron) from the background field that arises from imperfect shimming and variations in magnetic susceptibility of surrounding tissues (including air). We present a nonparametric background field removal method based on projection onto dipole fields in which the background field inside an ROI is decomposed into a field originating from dipoles outside the ROI using the projection theorem in Hilbert space.
摘要翻译：为了在敏感度加权成像和敏感性的准确定量中获得最佳图像质量，需要从由不均匀匀场引起的背景场和周围组织的磁化率变化中分离由局部磁源（如铁）产生的局部场（含空气）。我们提出了一种基于投影到偶极子场的非参数背景场去除方法，其中利用希尔伯特空间中的投影定理将ROI内部的背景场分解成源自ROI外的偶极子的场。

4. 发明申请

US20130221961A1 System, Process and Computer-Accessible Medium For Providing Quantitative Susceptibility Mapping 有权
标题翻译：系统，过程和计算机可访问介质，用于提供定量敏感性映射
公开(公告)号：US20130221961A1
公开(公告)日：2013-08-29
申请号：US13406137
申请日：2012-02-27
申请人： Tian Liu
发明人： Tian Liu
IPC分类号： G01R33/44
CPC分类号： G01R33/56545 , A61B5/0042 , A61B5/055 , G01R33/24 , G01R33/56536
摘要： Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian statistical approach. The likelihood is constructed directly using the complex data. A prior is constructed from matching structures or information content in known morphology. The quantitative susceptibility map can be determined by, e.g., maximizing the posterior. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining information associated with at least one structure. Using such exemplary embodiment, it is possible to receive signals associated with the structure(s), where the signals can include complex data that is in the complex domain.
摘要翻译：可以提供示例性的定量磁敏度测绘方法，系统和计算机可访问介质，以使用贝叶斯统计方法从复磁共振成像数据生成组织磁性的图像。直接使用复杂数据构建似然。先前是从已知形态的匹配结构或信息内容构建的。定量磁化率图可以通过例如使后方最大化来确定。因此，根据示例性实施例，可以提供系统，方法和计算机可访问介质来确定与至少一个结构相关联的信息。使用这样的示例性实施例，可以接收与结构相关联的信号，其中信号可以包括在复杂域中的复杂数据。

5. 发明申请

US20060054620A1 Collapsible and reusable container and method for use 有权
标题翻译：可折叠和可重复使用的容器和使用方法
公开(公告)号：US20060054620A1
公开(公告)日：2006-03-16
申请号：US10926429
申请日：2004-08-25
申请人： Xuewu Liu , Tian Liu , Xue Liu
发明人： Xuewu Liu , Tian Liu , Xue Liu
IPC分类号： B65D6/12
CPC分类号： B65D25/205 , B65D11/1853 , B65D65/466 , B65D81/36 , B65D2203/10 , B65D2211/00 , E02B3/108 , Y02W30/807
摘要： A collapsible and reusable shipping or storage container that easily collapses to a flat stackable package with no small or loose parts. Said container can be locked with a single locking mechanism in collapsed folded position or in fully open position with items inside. Said container is collapsed for return transport to distribution center to await reloading of future contents and thereby minimizes required space and preventing waste while in transport returning to distribution facility. To fold and collapse said container, top lid slides out and is lifted diagonally and removed from container, bottom panel is released and flipped up toward front side panel, collapsible sides are folded in and removed lid is placed into designated slot within collapsed container.
摘要翻译：一个可折叠和可重复使用的运输或存储容器，容易塌陷到没有小的或松散的零件的平坦的可堆叠包装。所述容器可以用单个锁定机构锁定在折叠的折叠位置或处于完全打开的位置，内部物品。所述容器被倒塌以返回到配送中心等待重新装载未来的内容物，从而最小化所需的空间并且在运输返回分配设施时防止浪费。为了折叠和折叠所述容器，顶盖滑出并被倾斜地提起并从容器中取出，底板被释放并朝向前侧板翻转，可折叠的侧面被折叠并且将盖子放置在收缩的容器内的指定的狭槽中。

6. 发明申请

US20110044524A1 TOOL FOR ACCURATE QUANTIFICATION IN MOLECULAR MRI 有权
标题翻译：用于精确定量分析MRI的工具
公开(公告)号：US20110044524A1
公开(公告)日：2011-02-24
申请号：US12990148
申请日：2009-04-28
申请人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
发明人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
IPC分类号： G06K9/00
CPC分类号： G01R33/54 , G01R33/5601 , G01R33/5608 , G01R33/563
摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.
摘要翻译：提供了用于磁源磁共振成像的方法和装置。该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示，例如磁化率的定量估计。附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。通过基于收集的信号和附加信息的反转操作来生成图像。反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

7. 外观设计

USD969525S1 Shelf 有权
公开(公告)号：USD969525S1
公开(公告)日：2022-11-15
申请号：US29787048
申请日：2021-06-03
申请人： Tian Liu
设计人： Tian Liu

8. 发明申请

US20140213924A1 METHODS, SYSTEMS AND COMPUTER READABLE STORAGE MEDIA STORING INSTRUCTIONS FOR DETERMINING RESPIRATORY INDUCED ORGAN MOTION 审中-公开
标题翻译：方法，系统和计算机可读存储介质存储指令用于确定呼吸道诱导的有机运动
公开(公告)号：US20140213924A1
公开(公告)日：2014-07-31
申请号：US14165771
申请日：2014-01-28
申请人： Mohammad K. Khan , Tian Liu , Yuting Lin
发明人： Mohammad K. Khan , Tian Liu , Yuting Lin
IPC分类号： A61B5/113
CPC分类号： A61B5/113 , A61B5/721 , A61N5/1049 , A61N5/1064 , A61N2005/1051
摘要： Methods, systems and computer-readable storage media relate to determining respiratory motion from motion data of a target to be treated. The methods may include processing motion data of a target to be treated obtained from at least one marker for at least one period. Each period including a plurality of time intervals. The processing including processing the motion data to determine an isocenter for each time interval along at least one of a plurality of axes of motion. The method may include determining at least one component of the motion data in at least one axis, the at least component corresponding to a subset of the motion data having a discrete value and/or a range of values; and determining respiratory motion from at least one component of the motion data. Radiotherapy treatment can be improved by determining the respiratory motion and the impact of respiration of a target.
摘要翻译：方法，系统和计算机可读存储介质涉及从待处理的目标的运动数据确定呼吸运动。所述方法可以包括在至少一个周期内从至少一个标记物处理待处理的靶标的运动数据。每个周期包括多个时间间隔。该处理包括处理运动数据以沿多个运动轴中的至少一个确定每个时间间隔的等角点。所述方法可以包括：在至少一个轴上确定运动数据的至少一个分量，所述至少部分对应于具有离散值和/或值范围的运动数据的子集; 以及从运动数据的至少一个分量确定呼吸运动。通过确定呼吸运动和目标呼吸的影响可以改善放射治疗。

9. 发明授权

US08781197B2 Tool for accurate quantification in molecular MRI 有权
标题翻译：分子MRI准确定量的工具
公开(公告)号：US08781197B2
公开(公告)日：2014-07-15
申请号：US12990148
申请日：2009-04-28
申请人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
发明人： Yi Wang , Ludovic de Rochefort , Bryan Kressler , Tian Liu , Pascal Spincemaille
IPC分类号： G06K9/00
CPC分类号： G01R33/54 , G01R33/5601 , G01R33/5608 , G01R33/563
摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.
摘要翻译：提供了用于磁源磁共振成像的方法和装置。该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示，例如磁化率的定量估计。附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。通过基于收集的信号和附加信息的反转操作来生成图像。反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

10. 发明授权

US09213076B2 System, process and computer-accessible medium for providing quantitative susceptibility mapping 有权
标题翻译：系统，过程和计算机可访问介质，用于提供定量敏感性映射
公开(公告)号：US09213076B2
公开(公告)日：2015-12-15
申请号：US13406137
申请日：2012-02-27
申请人： Tian Liu
发明人： Tian Liu
IPC分类号： G01R33/565 , A61B5/055 , G01R33/24 , A61B5/00
CPC分类号： G01R33/56545 , A61B5/0042 , A61B5/055 , G01R33/24 , G01R33/56536
摘要： Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian statistical approach. The likelihood is constructed directly using the complex data. A prior is constructed from matching structures or information content in known morphology. The quantitative susceptibility map can be determined by, e.g., maximizing the posterior. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining information associated with at least one structure. Using such exemplary embodiment, it is possible to receive signals associated with the structure(s), where the signals can include complex data that is in the complex domain.
摘要翻译：可以提供示例性的定量磁敏度测绘方法，系统和计算机可访问介质，以使用贝叶斯统计方法从复磁共振成像数据生成组织磁性的图像。直接使用复杂数据构建似然。先前是从已知形态的匹配结构或信息内容构建的。定量磁化率图可以通过例如使后方最大化来确定。因此，根据示例性实施例，可以提供系统，方法和计算机可访问介质来确定与至少一个结构相关联的信息。使用这样的示例性实施例，可以接收与结构相关联的信号，其中信号可以包括在复杂域中的复杂数据。

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