专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07696223B2 Pyrrolo- and Thiazolo-pyridine compounds, and methods of use thereof 有权
标题翻译：吡咯并噻唑并吡啶化合物及其使用方法
公开(公告)号：US07696223B2
公开(公告)日：2010-04-13
申请号：US11696549
申请日：2007-04-04
申请人： Shaojiang Deng , Min Wu , Eric D. Turtle , Wen-Bin Ho , Michael P. Arend , Heng Cheng , Lee A. Flippin
发明人： Shaojiang Deng , Min Wu , Eric D. Turtle , Wen-Bin Ho , Michael P. Arend , Heng Cheng , Lee A. Flippin
IPC分类号： A61K31/435 , C07D471/02
CPC分类号： C07D471/04 , C07D513/04
摘要： The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF).
摘要翻译：本发明涉及能够调节缺氧诱导因子（HIF）的稳定性和/或活性的新型化合物。

2. 发明授权

US08703795B2 Thienopyridine compounds, and methods of use thereof 有权
标题翻译：噻吩并吡啶化合物及其使用方法
公开(公告)号：US08703795B2
公开(公告)日：2014-04-22
申请号：US11367969
申请日：2006-03-02
申请人： Eric D. Turtle , Lee A. Flippin , Michael P. Arend , Heng Cheng
发明人： Eric D. Turtle , Lee A. Flippin , Michael P. Arend , Heng Cheng
IPC分类号： A61K31/4365 , C07D495/04
CPC分类号： C07D495/04 , C07D498/02
摘要： The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF).
摘要翻译：本发明涉及能够调节缺氧诱导因子（HIF）的稳定性和/或活性的新型化合物。

3. 发明授权

US08269008B2 Oxazolopyridine and isoxazolopyridine derivatives for use in the treatment of HIF-mediated conditions 有权
标题翻译：恶唑吡啶和异恶唑吡啶衍生物，用于治疗HIF介导的病症
公开(公告)号：US08269008B2
公开(公告)日：2012-09-18
申请号：US12734895
申请日：2008-12-02
申请人： Michael P. Arend , Heng Cheng , Lee A. Flippin , Danny Ng , Eric D. Turtle , Min Wu
发明人： Michael P. Arend , Heng Cheng , Lee A. Flippin , Danny Ng , Eric D. Turtle , Min Wu
IPC分类号： C07D221/18 , C07D221/02 , C07D221/22 , A01N43/42 , A01N43/40 , A61K31/44 , A61K31/435 , A61P25/00 , A61P3/04 , C07C63/00 , C07C65/00 , C12N9/99 , C12N9/14
CPC分类号： C07D498/04
摘要： The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme.
摘要翻译：本发明涉及能够通过抑制至少一种HIF羟化酶的活性来调节缺氧诱导因子（HIF）的稳定性和/或活性的新型化合物。

4. 发明申请

US20100303928A1 ISOXAZOLOPYRIDINE DERIVATIVES FOR USE IN THE TREATMENT OF HIF-MEDIATED CONDITIONS 有权
标题翻译：用于治疗HIF介导的病症的异丙嗪吡啶衍生物
公开(公告)号：US20100303928A1
公开(公告)日：2010-12-02
申请号：US12734895
申请日：2008-12-02
申请人： Michael P. Arend , Heng Cheng , Lee A. Flippin , Danny Ng , Eric D. Turtle , Min Wu
发明人： Michael P. Arend , Heng Cheng , Lee A. Flippin , Danny Ng , Eric D. Turtle , Min Wu
IPC分类号： A61K31/437 , C07D498/04 , A61K31/714 , A61K31/519 , A61K33/26 , A61K38/18 , A61P9/10 , C12N9/99
CPC分类号： C07D498/04
摘要： The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme.
摘要翻译：本发明涉及能够通过抑制至少一种HIF羟化酶的活性来调节缺氧诱导因子（HIF）的稳定性和/或活性的新型化合物。

5. 发明申请

US20070034775A1 Calibrated LED light module 有权
公开(公告)号：US20070034775A1
公开(公告)日：2007-02-15
申请号：US11205580
申请日：2005-08-15
申请人： Heng Cheng , Kee Ng , Joon Lee
发明人： Heng Cheng , Kee Ng , Joon Lee
IPC分类号： H01J40/14
CPC分类号： H05B33/0869 , H01L25/167 , H01L2924/0002 , H05B33/0821 , H05B33/0866 , H01L2924/00
摘要： A light source and method for making the same are disclosed. The light source includes a plurality of LEDs mounted on a substrate and a sensor for measuring light from the LEDs. Each LED emits light having a different spectrum from the other LEDs, the average intensity of light from that LED being determined by a drive signal coupled to that LED. The sensor generates a plurality of signals, each signal being characterized by a sensor value that is proportional to the intensity of light emitted by a corresponding one of the LEDs. A controller generates the drive signals and stores a current target value for each LED. The drive signals for each of the LEDs is generated such that the sensor value for that LED matches the stored current target value for that LED.

6. 发明申请

US20060261742A1 Phosphor converted light source 有权
标题翻译：磷光转换光源
公开(公告)号：US20060261742A1
公开(公告)日：2006-11-23
申请号：US11135712
申请日：2005-05-23
申请人： Kee Ng , Heng Cheng , Janet Chua
发明人： Kee Ng , Heng Cheng , Janet Chua
IPC分类号： H05B37/00
CPC分类号： H05B33/0818 , H05B33/0821 , H05B33/0863 , H05B33/0869 , Y10S362/80
摘要： A light source having first and second phosphor-converted component light sources is disclosed. The first component light source includes a first LED that emits light at a first wavelength and a first luminescent conversion material layer that converts light of the first wavelength to light of a first output wavelength, and the second component light source includes a second LED that emits light at a second wavelength and a second luminescent conversion material layer that converts light of the second wavelength to light of a second output wavelength that is different from the first output wavelength. The first and second LEDs are constructed in the same material system, preferably in the same batch of wafers on the fabrication line. A controller generates a current through each of the first and second LEDs that results in the light source generating light that is perceived to be a predetermined color.
摘要翻译：公开了具有第一和第二磷光体转换组件光源的光源。第一分量光源包括发射第一波长的光的第一LED和将第一波长的光转换成第一输出波长的光的第一发光转换材料层，并且第二分量光源包括发射的第二LED 第二波长的光和将第二波长的光转换成与第一输出波长不同的第二输出波长的光的第二发光转换材料层。第一和第二LED被构造在相同的材料系统中，优选地在制造线上的同一批晶圆中。控制器通过导致光源产生感知为预定颜色的光的每个第一和第二LED产生电流。

7. 发明申请

US20110027274A1 ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF 有权
标题翻译：抗生素化合物，其结合物及其用途及其用途
公开(公告)号：US20110027274A1
公开(公告)日：2011-02-03
申请号：US12846493
申请日：2010-07-29
申请人： Heng Cheng , Qiang Cong , Sanjeev Gangwar , Qian Zhang
发明人： Heng Cheng , Qiang Cong , Sanjeev Gangwar , Qian Zhang
IPC分类号： A61K39/395 , C07K5/10 , C07K16/00 , C07C205/00 , C07C229/00
CPC分类号： C07K7/06 , A61K38/06 , A61K47/6811 , A61K47/6829 , C07C229/14 , C07C229/16 , C07K5/021 , C07K5/06139 , C07K5/10 , C07K16/18
摘要： Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody:
摘要翻译：具有由式（II）表示的结构的抗增殖化合物，其中n，R 1，R 2，R 3，R 4和R 5如本文所定义，可任选地当与配体例如抗体缀合时用于治疗肿瘤：

8. 发明申请

US20060199836A1 Novel thienopyridine compounds, and methods of use thereof 有权
标题翻译：新型噻吩并吡啶化合物及其使用方法
公开(公告)号：US20060199836A1
公开(公告)日：2006-09-07
申请号：US11367969
申请日：2006-03-02
申请人： Eric Turtle , Lee Flippin , Michael Arend , Heng Cheng
发明人： Eric Turtle , Lee Flippin , Michael Arend , Heng Cheng
IPC分类号： A61K31/4743 , C07D498/02
CPC分类号： C07D495/04 , C07D498/02
摘要： The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF).
摘要翻译：本发明涉及能够调节缺氧诱导因子（HIF）的稳定性和/或活性的新型化合物。

9. 发明申请

US20060126326A1 Light-emitting diode flash module with enhanced spectral emission 有权
标题翻译：具有增强的光谱发射的发光二极管闪光灯模块
公开(公告)号：US20060126326A1
公开(公告)日：2006-06-15
申请号：US11012761
申请日：2004-12-15
申请人： Kee Ng , Heng Cheng , Yew Kuan
发明人： Kee Ng , Heng Cheng , Yew Kuan
IPC分类号： F21V9/00
CPC分类号： H04N5/2256 , F21K9/00 , G03B15/03 , H01L25/0753 , H01L33/504 , H01L2224/48091 , H01L2924/12041 , H04M1/22 , Y10S362/80 , H01L2924/00014
摘要： A light-emitting diode (“LED”) device includes a plurality of LEDs. Each LED in the plurality of LEDs is adjacent to at least one other of the plurality of LEDs. At least one of the plurality of LEDs has a radiation with a full-width-half-maximum greater than 50 nm.
摘要翻译：发光二极管（“LED”）器件包括多个LED。多个LED中的每个LED与多个LED中的至少另一个相邻。多个LED中的至少一个LED具有大于50nm的全宽半最大值的辐射。

10. 发明申请

US20060000963A1 Light source calibration 审中-公开
标题翻译：光源校准
公开(公告)号：US20060000963A1
公开(公告)日：2006-01-05
申请号：US10880949
申请日：2004-06-30
申请人： Kee Ng , Heng Cheng , Joon Lee
发明人： Kee Ng , Heng Cheng , Joon Lee
IPC分类号： G01J1/32
CPC分类号： G01J1/32 , G01J3/10
摘要： A light source is calibrated and operated. During calibration of the light source, calibration light is provided from a calibration light source. The calibration light is detected. A representation of the detected calibration light is stored. During operation of the light source, light is generated by the light source. The light generated by the light source is detected. The detected light generated by the light source is compared with the stored representation of the detected calibration light to generate information used to control color of the light generated by the light source.
摘要翻译：光源经过校准和操作。在校准光源期间，校准光源由校准光源提供。检测到校准光。存储检测到的校准光的表示。在光源操作期间，由光源产生光。检测由光源产生的光。将由光源产生的检测光与检测到的校准光的存储表示进行比较，以产生用于控制由光源产生的光的颜色的信息。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式