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    • 1. 发明授权
    • Method of dividing past computing instances into predictable and unpredictable sets and method of predicting computing value
    • 将过去的计算实例划分为可预测和不可预测的集合的方法以及预测计算值的方法
    • US07720771B1
    • 2010-05-18
    • US11165810
    • 2005-06-24
    • Eric AndersonDirk BeyerIra CohenTerence P. KellyJanet Wiener
    • Eric AndersonDirk BeyerIra CohenTerence P. KellyJanet Wiener
    • G06F15/18
    • G06N99/005
    • An embodiment of a method of dividing past computing instances into predictable and unpredictable sets begins with a first step of a computing entity storing a training data set comprising past computing instances. Each past computing instance comprises attributes and a past computing value. In a second step, the computing entity separates the training data set into a predictable set of past computing instances and an unpredictable set of past computing instances. According to an embodiment, a method of predicting a computing value begins with the first and second steps. The method of predicting the computing value continues with a third step of the computing entity forming a predictor from the predictable set of past computing instances. In a fourth step, the computing entity applies the predictor to a pending computing instance that meets a predictability test to determine a predicted value for the pending computing instance.
    • 将过去的计算实例划分为可预测和不可预测的集合的方法的实施例开始于存储包括过去的计算实例的训练数据集的计算实体的第一步骤。 每个过去的计算实例包括属性和过去的计算值。 在第二步骤中,计算实体将训练数据集分成可预测的一组过去的计算实例和不可预测的一组过去的计算实例。 根据实施例,预测计算值的方法从第一和第二步骤开始。 预测计算值的方法继续,计算实体的第三步从预测的一组过去的计算实例形成预测器。 在第四步骤中,计算实体将预测器应用于满足可预测性测试的待决计算实例以确定未决计算实例的预测值。
    • 6. 发明申请
    • Electronic voting system
    • 电子投票系统
    • US20080110985A1
    • 2008-05-15
    • US11975401
    • 2007-10-19
    • Barry CohenIra Cohen
    • Barry CohenIra Cohen
    • G07C13/00
    • G07C13/00
    • A method is described that involves creating a private key and a public key cryptographic key pair, generating a unique and random identifier for a voter's vote and accepting an election vote from said voter. The vote and identifier are electronically signed with the private key to create a digital signature. The vote and identifier are provided in a human readable format to the voter. The digital signature is provided to the voter. The method further involves generating a second unique and random identifier for a second voter's vote and accepting a second election vote from the second voter. The second vote and identifier are electronically signed with the private key to create a second digital signature. The second vote and second identifier are provided in a human readable format to the second voter. The second digital signature is provided to the second voter. The public key is published on an internet. Information is publicly provided on the internet that associates together: (i) the voter's vote in a human readable format, (ii) the identifier in a human readable format, and (iii) the digital signature. The voter's vote is verifiable with the digital signature and the public key. Information is publicly provided on the internet that associates together: (iv) the second voter's vote in a human readable format, (v) the second identifier in a human readable format, and (vi) the second digital signature. The second voter's vote is verifiable with the second digital signature and the public key. The method includes, in response to receiving a request from the internet containing the identifier, providing (i), (ii) and (iii) above through an internet communication. The method also includes in response to receiving a second request from the internet containing the second identifier, providing (iv), (v) and (vi) above through a second internet communication.
    • 描述了一种方法,其涉及创建私钥和公共密钥密码对,为选民投票产生唯一且随机的标识符,并接受所选投票者的选举投票。 投票和标识符用私钥用电子签名来创建数字签名。 投票和标识符以人类可读格式提供给选民。 数字签名提供给选民。 该方法还包括为第二选民投票产生第二唯一和随机的标识符,并从第二选民接受第二选举投票。 第二票和标识符用私钥电子签名以创建第二数字签名。 第二投票和第二标识符以人类可读格式提供给第二选民。 第二个数字签名被提供给第二个选民。 公共密钥在互联网上发布。 在互联网上公开提供信息,其联系在一起:(i)以人类可读格式投票,(ii)以人类可读格式的标识符,以及(iii)数字签名。 选民的投票可以通过数字签名和公钥来验证。 在互联网上公开提供信息,其联系在一起:(iv)第二选民以人类可读格式的投票,(v)以人类可读格式的第二标识符,和(vi)第二数字签名。 第二个选民投票可以通过第二个数字签名和公钥来验证。 该方法包括响应于从互联网接收到包含标识符的请求,通过互联网通信提供上述(i),(ii)和(iii)。 该方法还包括响应于从互联网接收包含第二标识符的第二请求,通过第二互联网通信提供上述(iv),(v)和(vi)。
    • 7. 发明申请
    • High throughput biological heart rate monitor that is molecularly determined
    • 分子确定的高通量生物心率监测仪
    • US20070042347A1
    • 2007-02-22
    • US11520527
    • 2006-09-12
    • Michael RosenRichard RobinsonIra CohenHan-Gang Yu
    • Michael RosenRichard RobinsonIra CohenHan-Gang Yu
    • C12Q1/00
    • G01N33/6872A61K38/1709A61K48/00G01N33/5008G01N33/502G01N33/5061
    • This invention provides for a chamber and system designed for use in assaying drug effects on heart rate. The chamber consists of a series of wells, each 3 mm by 3 mm in inner diameter. Cardiac myocytes disaggregated from neonatal animals are plated onto the bottom of each well and grown under standard tissue culture conditions. The chamber holds from 24-96 such wells. When drugs are to be assayed, the cells in each well are loaded with a calcium sensitive dye and the beating rate in each is monitored with a photodiode. Drug is added in graded concentrations to each well, and equilibrated and effects on rate are observed. This construct permits use of a cell based bioassay for the study of drugs or agents that may alter cardiac rate. This invention can be used in high throughput screening of drugs to evaluate/predict their effects on cardiac rate and rhythm. Further provided for by this invention is a A vector which comprises a compound which encode an ion channel.
    • 本发明提供了一种设计用于测定药物对心率的影响的室和系统。 该室由一系列的孔组成,内径为3 mm×3 mm。 将从新生儿动物分解的心肌细胞接种在每个孔的底部并在标准组织培养条件下生长。 该厅拥有24-96个这样的井。 当要测定药物时,每个孔中的细胞装载有钙敏感染料,并且用光电二极管监测每个孔中的搏动速率。 将药物以分级浓度加入每个孔中,并平衡并观察其对速率的影响。 该构建允许使用基于细胞的生物测定法来研究可能改变心率的药物或药剂。 本发明可用于药物的高通量筛选以评估/预测其对心率和节律的影响。 本发明进一步提供的是包含编码离子通道的化合物的A载体。