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1. 发明申请

US20070233244A1 Artificial Disc Replacement Using Posterior Approach 审中-公开
公开(公告)号：US20070233244A1
公开(公告)日：2007-10-04
申请号：US11277726
申请日：2006-03-28
申请人： Erasmo Lopez , Amie Borgstrom , SeungKyu Kwak , John Hawkins , Charles Bartish
发明人： Erasmo Lopez , Amie Borgstrom , SeungKyu Kwak , John Hawkins , Charles Bartish
IPC分类号： A61F2/44
CPC分类号： A61F2/4425 , A61F2002/3008 , A61F2002/30112 , A61F2002/30133 , A61F2002/30151 , A61F2002/30153 , A61F2002/30179 , A61F2002/30387 , A61F2002/30563 , A61F2002/30571 , A61F2002/30604 , A61F2002/30649 , A61F2002/30884 , A61F2002/30975 , A61F2220/0025 , A61F2230/0004 , A61F2230/0015 , A61F2230/0017 , A61F2230/0019 , A61F2230/0058 , A61F2250/0098
摘要： Methods and devices are provided for replacing a spinal disc. In an exemplary embodiment, artificial disc replacements and methods are provided wherein at least a portion of a disc replacement can be implanted using a posterolateral approach. With a posterolateral approach, the spine is accessed more from the side of the spinal canal through an incision formed in the patient's back. A pathway is created from the incision to the disc space between adjacent vertebrae. Portions of the posterolateral annulus, and posterior lip of the vertebral body may be removed to access the disc space, leaving the remaining annulus and the anterior and posterior longitudinal ligaments in tact. The disc implant can be at least partially introduced using a posterolateral approach, yet it has a size that is sufficient to restore height to the adjacent vertebrae, and that is sufficient to maximize contact with the endplates of the adjacent vertebrae.

2. 发明申请

US20070233261A1 Artificial Disc Replacement Using Posterior Approach 有权
标题翻译：使用后方法进行人造椎间盘置换
公开(公告)号：US20070233261A1
公开(公告)日：2007-10-04
申请号：US11277725
申请日：2006-03-28
申请人： Erasmo Lopez , Amie Borgstrom , SeungKyu Kwak , John Hawkins , Charles Bartish
发明人： Erasmo Lopez , Amie Borgstrom , SeungKyu Kwak , John Hawkins , Charles Bartish
IPC分类号： A61F2/44
CPC分类号： A61F2/4425 , A61F2002/3008 , A61F2002/30112 , A61F2002/30133 , A61F2002/30151 , A61F2002/30153 , A61F2002/30179 , A61F2002/30387 , A61F2002/30563 , A61F2002/30571 , A61F2002/30604 , A61F2002/30649 , A61F2002/30884 , A61F2002/30975 , A61F2220/0025 , A61F2230/0004 , A61F2230/0015 , A61F2230/0017 , A61F2230/0019 , A61F2230/0058 , A61F2250/0098
摘要： Methods and devices are provided for replacing a spinal disc. In an exemplary embodiment, artificial disc replacements and methods are provided wherein at least a portion of a disc replacement can be implanted using a posterolateral approach. With a posterolateral approach, the spine is accessed more from the side of the spinal canal through an incision formed in the patient's back. A pathway is created from the incision to the disc space between adjacent vertebrae. Portions of the posterolateral annulus, and posterior lip of the vertebral body may be removed to access the disc space, leaving the remaining annulus and the anterior and posterior longitudinal ligaments in tact. The disc implant can be at least partially introduced using a posterolateral approach, yet it has a size that is sufficient to restore height to the adjacent vertebrae, and that is sufficient to maximize contact with the endplates of the adjacent vertebrae.
摘要翻译：提供了用于替换脊椎盘的方法和装置。在示例性实施例中，提供了人造椎间盘置换和方法，其中可以使用后外侧方法植入椎间盘置换的至少一部分。通过后外侧方法，脊柱通过在患者背部形成的切口从脊柱管侧进入。从切口到相邻椎骨之间的椎间盘间隙产生通路。后外侧环的部分和椎体的后唇可以被移除以进入椎间盘空间，留下剩余的环和前后纵韧带。椎间盘植入物可以使用后外侧方法至少部分地引入，但其具有足以恢复相邻椎骨的高度的尺寸，并且足以使与邻近椎骨的端板最大程度的接触。

3. 发明申请

US20070213821A1 Intervertebral disc prosthesis having multiple bearing surfaces 有权
标题翻译：椎间盘假体具有多个支承面
公开(公告)号：US20070213821A1
公开(公告)日：2007-09-13
申请号：US11351710
申请日：2006-02-10
申请人： SeungKyu Kwak , Amie Borgstrom , Erasmo Lopez , John Hawkins
发明人： SeungKyu Kwak , Amie Borgstrom , Erasmo Lopez , John Hawkins
IPC分类号： A61F2/44
CPC分类号： A61F2/4425 , A61F2002/30016 , A61F2002/30112 , A61F2002/30331 , A61F2002/30433 , A61F2002/30448 , A61F2002/30563 , A61F2002/30649 , A61F2002/30884 , A61F2002/30902 , A61F2002/443 , A61F2002/448 , A61F2220/0033 , A61F2220/0041 , A61F2220/005 , A61F2230/0004 , A61F2250/0019 , A61F2310/00011 , A61F2310/00179
摘要： An intervertebral disc prosthesis comprises a left prosthesis component and a symmetric right prosthesis component positioned in an intervertebral space. Each prosthesis component includes a superior vertebra facing surface, an inferior vertebra facing surface, and a substantially spherical bearing surface. The bearing surface is positioned between the superior vertebra facing surface and the inferior vertebra facing surface. The superior vertebra facing surface is provided on a superior endplate and the inferior vertebra facing surface is provided on an inferior endplate. The superior endplate is operable to rotate relative to the inferior endplate upon the bearing surface. Each prosthesis component further comprises an elastic member positioned between an endplate and the bearing surface. The elastic member may be substantially cylindrical with a plurality of resilient ribs. Flexion/extension, lateral bending, and torsional movement are allowed by a combination of endplate rotation upon the bearing surface and compression of the elastic member.
摘要翻译：椎间盘假体包括定位在椎间空间中的左假体部件和对称右假体部件。每个假体部件包括上面的椎骨面向表面，下面的椎骨面对表面和基本上球形的支承表面。轴承表面位于上椎骨面对面和下椎骨面对面之间。上面的上脊椎骨表面设置在上端板上，下椎骨面向上设置在下端板上。上端板可操作以在轴承表面上相对于下端板旋转。每个假体部件还包括定位在端板和支承表面之间的弹性部件。弹性构件可以是大致圆柱形的，具有多个弹性肋。弯曲/延伸，侧向弯曲和扭转运动通过端板在轴承表面上的旋转和弹性构件的压缩的组合来允许。

4. 发明申请

US20050203512A1 Posterior process dynamic spacer 有权
标题翻译：后处理动态间隔
公开(公告)号：US20050203512A1
公开(公告)日：2005-09-15
申请号：US10796359
申请日：2004-03-09
申请人： John Hawkins , Amie Borgstrom , William Dunbar , Seungkyu Kwak
发明人： John Hawkins , Amie Borgstrom , William Dunbar , Seungkyu Kwak
IPC分类号： A61B17/00 , A61B17/70 , A61F2/44 , B01J23/00 , C07D301/06 , C07D301/12
CPC分类号： A61B17/7062 , A61B17/7065 , A61B17/7068 , A61B2017/00867
摘要： An interspinous spacer having a memory metal extension.
摘要翻译：具有记忆金属延伸部的棘突间间隔物。

5. 发明申请

US20050055096A1 Functional spinal unit prosthetic 审中-公开
标题翻译：功能性脊柱单位假体
公开(公告)号：US20050055096A1
公开(公告)日：2005-03-10
申请号：US10850280
申请日：2004-05-20
申请人： Hassan Serhan , Robert Labrom , John Hawkins , William Dunbar , Amie Borgstrom , Seungkyu Kwak , Andrew Dooris , Michael Slivka
发明人： Hassan Serhan , Robert Labrom , John Hawkins , William Dunbar , Amie Borgstrom , Seungkyu Kwak , Andrew Dooris , Michael Slivka
IPC分类号： A61B17/04 , A61B17/70 , A61F2/00 , A61F2/02 , A61F2/08 , A61F2/30 , A61F2/44
CPC分类号： A61F2/4405 , A61B17/0401 , A61B17/7011 , A61B17/7064 , A61F2/08 , A61F2/30 , A61F2/30742 , A61F2/30965 , A61F2/442 , A61F2/4425 , A61F2/4455 , A61F2002/30014 , A61F2002/30032 , A61F2002/30062 , A61F2002/30224 , A61F2002/30242 , A61F2002/30383 , A61F2002/30462 , A61F2002/30507 , A61F2002/30553 , A61F2002/30563 , A61F2002/30565 , A61F2002/30578 , A61F2002/30649 , A61F2002/30662 , A61F2002/30673 , A61F2002/30682 , A61F2002/30772 , A61F2002/30774 , A61F2002/30777 , A61F2002/30841 , A61F2002/443 , A61F2210/0004 , A61F2220/0025 , A61F2220/0075 , A61F2230/0069 , A61F2230/0071 , A61F2250/0008 , A61F2250/0018 , A61F2250/003 , A61F2310/00011 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00161 , A61F2310/00179 , A61F2310/00365 , A61F2310/00796 , A61F2310/00976
摘要： A facet joint replacement system having an elongate rod and a polyaxial screw having a groove therein, wherein the rod is slidably received within the groove of the polyaxial screw.
摘要翻译：一种小关节置换系统，其具有细长杆和在其中具有凹槽的多轴螺钉，其中杆可滑动地容纳在多轴螺钉的凹槽内。

6. 发明申请

US20060271046A1 FACET JOINT REPLACEMENT 有权
标题翻译： FACET联合替代
公开(公告)号：US20060271046A1
公开(公告)日：2006-11-30
申请号：US10908882
申请日：2005-05-31
申请人： Seungkyu Daniel Kwak , John Hawkins , Amie Borgstrom , William Dunbar
发明人： Seungkyu Daniel Kwak , John Hawkins , Amie Borgstrom , William Dunbar
IPC分类号： A61F2/30
CPC分类号： A61B17/7064 , A61B17/70 , A61B17/7011 , A61B17/7019 , A61B17/7023 , A61B17/7025 , A61B17/7031 , A61B17/7035 , A61B17/7043 , A61B17/7046 , A61B17/7049 , A61F2/4405 , A61F2/442 , A61F2/4425 , A61F2002/30331 , A61F2002/3037 , A61F2002/30372 , A61F2002/30649 , A61F2002/448 , A61F2220/0033
摘要： Various methods and devices for replacing damaged, injured, diseased, or otherwise unhealthy posterior elements, such as the facet joints, the lamina, the posterior ligaments, and/or other features of a patient's spinal column, are provided. In one exemplary embodiment, the methods and devices are effective to mimic the natural function of the spine by allowing flexion, extension, and lateral bending of the spine, while substantially restricting posterior-anterior shear and rotation of the spine.
摘要翻译：提供用于替换损伤的，受伤的，患病的或其他不健康的后部元件（例如小关节，椎板，后韧带和/或患者的脊柱的其他特征）的各种方法和装置。在一个示例性实施例中，所述方法和装置通过允许脊柱的弯曲，延伸和侧向弯曲来模拟脊柱的自然功能是有效的，同时基本上限制脊柱的前后剪切和旋转。

7. 发明申请

US20070161992A1 Rotatable interspinous spacer 有权
标题翻译：可旋转椎间盘
公开(公告)号：US20070161992A1
公开(公告)日：2007-07-12
申请号：US11315660
申请日：2005-12-22
申请人： Seungkyu Kwak , John Hawkins
发明人： Seungkyu Kwak , John Hawkins
IPC分类号： A61F2/30
CPC分类号： A61B17/7065 , Y10S606/902
摘要： An interspinous spacer having opposed, pivotally connected s-shaped members that can enter the interspinous space in an initial state and then rotate to a final state to secure the implant to the adjacent interspinous processes.
摘要翻译：棘突间间隔物具有相对的，可枢转地连接的S形构件，其能够以初始状态进入棘突间空间，然后旋转到最终状态以将植入物固定到相邻的棘突间过程。

8. 发明授权

US09254264B2 Compositions and uses thereof 有权
标题翻译：组合物及其用途
公开(公告)号：US09254264B2
公开(公告)日：2016-02-09
申请号：US12865922
申请日：2009-02-06
申请人： John Hawkins
发明人： John Hawkins
IPC分类号： A61K9/10 , A23L1/035 , A23L1/30 , A61K31/167 , A61K47/12 , A61K47/24 , A61K47/26
CPC分类号： A61K9/10 , A23L29/10 , A23L33/10 , A61K31/167 , A61K47/12 , A61K47/24 , A61K47/26
摘要： The present invention provides structured surfactant systems comprising water and from 0 to saturation of sugar, together with sufficient surfactant to form a structure capable of suspending solids, wherein the surfactant comprises a mixture of: (i) a major portion of at least one sugar ester and/or a triterpenoid glycoside (saponin) having an HLB greater than 10; and (ii) a minor portion of at least one fatty acid and/or lecithin. The invention further provides pharmaceutical compositions comprising a structured surfactant system of the invention and a pharmaceutical or veterinary active ingredient.
摘要翻译：本发明提供包含水和0至饱和糖的结构化表面活性剂体系，以及足够的表面活性剂以形成能够悬浮固体的结构，其中所述表面活性剂包含以下混合物：（i）至少一种糖酯的主要部分和/或HLB大于10的三萜糖苷（皂角苷）; 和（ii）少部分至少一种脂肪酸和/或卵磷脂。本发明还提供了包含本发明的结构化表面活性剂体系和药物或兽用活性成分的药物组合物。

9. 发明授权

US08639693B1 Personalized place recommendations using collections of place listings 有权
标题翻译：个性化的地方建议使用收藏的地方列表
公开(公告)号：US08639693B1
公开(公告)日：2014-01-28
申请号：US13294602
申请日：2011-11-11
申请人： John Hawkins , Andrew Eland , Bernhard Seefeld
发明人： John Hawkins , Andrew Eland , Bernhard Seefeld
IPC分类号： G06F17/30
CPC分类号： G06F17/30867 , G06F17/3087
摘要： Personal recommendations are provided to users based on a relationship between place listings which with a user has interacted and collections of place listings. The user may interact with a place listing by reviewing the place, or accessing a web page that includes user-reviewed places. The collections of place listings are used to calculate a recommendation score for a candidate listing based on aggregate co-occurrence of the place listing and the candidate listing in the collections. The recommendation scores identify a probability that the user would appreciate the candidate listing based on the user's interaction with the place listing. Justifications may also be provided for display on the user's device to identify the relevance of the recommended listing.
摘要翻译：基于与用户已经交互的地点列表与地点列表的集合之间的关系向用户提供个人建议。用户可以通过查看该地点或访问包含用户审查地点的网页与地点列表进行交互。地点列表的集合用于基于集合中的地点列表和候选列表的聚合共现来计算候选列表的推荐分数。推荐分数根据用户与地点列表的交互来确定用户将欣赏候选者列表的概率。还可以提供说明以在用户设备上显示以识别推荐列表的相关性。

10. 发明申请

US20110185382A2 GENERATING REACH AND FREQUENCY DATA FOR TELEVISION ADVERTISEMENTS 审中-公开
标题翻译：生成用于电视广告的接收和频率数据
公开(公告)号：US20110185382A2
公开(公告)日：2011-07-28
申请号：US12247069
申请日：2008-10-07
申请人： John Hawkins , Simon Rowe
发明人： John Hawkins , Simon Rowe
IPC分类号： H04N7/025
CPC分类号： H04H20/14 , G06Q30/02 , H04H60/66 , H04N7/16 , H04N21/2407 , H04N21/25891 , H04N21/26603 , H04N21/4667 , H04N21/6582 , H04N21/812
摘要： Television reporting records are accessed and processed to generate frequency specific reach values and device frequencies for creatives (e.g., television advertisements). The device frequencies indicating the number of times a creative was presented by use of a particular viewing device. The frequency specific reach values indicating the number of unique viewing devices that were used to present the creative a specified number of times. Estimating frequency specific reach values and device frequencies for a creative for a viewing population. The estimated frequency specific reach values and device frequencies for the viewing population are based on known viewing pattern data for multiple creative airings from a sample of the viewing population (e.g., a subset of the viewing population) and estimated viewing pattern data for the airings for the viewing population.
摘要翻译：访问和处理电视报告记录以产生广告素材的频率特定到达值和设备频率（例如，电视广告）。设备频率指示通过使用特定观看设备呈现广告素材的次数。频率特定达到值，指示用于向广告素材呈现指定次数的唯一查看设备的数量。估计观看群体的广告素材的特定频率值和设备频率。用于观看群体的估计频率特定到达值和设备频率基于用于从观看群体的样本（例如，观看群体的子集）的多个创意播放的已知观看模式数据和用于播放的估计的观看模式数据观众人数。

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