专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP2455072A1 Controlled release formulations of octreotide 审中-公开
标题翻译：奥曲肽的控释剂型
公开(公告)号：EP2455072A1
公开(公告)日：2012-05-23
申请号：EP12156089.0
申请日：2006-03-10
申请人： Endo Pharmaceuticals Solutions Inc.
发明人： Kuzma, Petr , Decker, Stephanie
IPC分类号： A61K9/50 , A61K9/52 , A61K38/31
CPC分类号： A61K38/31 , A61K9/0024 , A61K47/32
摘要： A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two months. Methods of treating acromegaly, decreasing growth hormone, decreasing IGF-1, and treating conditions associated with carcinoid tumors and VIPomas by administering a controlled release formulation of octreotide are provided herein.
摘要翻译：奥曲肽或其药学上可接受的盐的制剂，其提供治疗有效量的奥曲肽的控制释放至少约两个月的时间。本文提供了通过施用奥曲肽的控释制剂治疗肢端肥大症，降低生长激素，降低IGF-1和治疗与类癌瘤和VIP瘤有关的病症的方法。

2. 发明公开

EP2805709A1 Manufacture of long term drug delivery devices with polyurethane 审中-公开
标题翻译： Herstellung von Vorrichtungen zur Langzeitarzneimittelversorgung mit polyurethan
公开(公告)号：EP2805709A1
公开(公告)日：2014-11-26
申请号：EP14172031.8
申请日：2004-08-11
申请人： Endo Pharmaceuticals Solutions Inc.
发明人： Kuo, Sheng-hung , Kuzma, Petr
IPC分类号： A61K9/00
CPC分类号： A61L31/10 , A61K9/0024 , A61K9/0092 , A61L27/54 , A61M5/14 , B65B3/003 , Y10T29/49826
摘要： This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.
摘要翻译：本发明涉及聚氨酯基聚合物作为药物递送装置在长时间内以恒定速率递送生物活性化合物及其制造方法的用途。该装置非常生物相容性和生物稳定性，并且可用作患者（人和动物）中用于将合适的生物活性物质递送至组织或器官的植入物。用于释放一个或多个药物以受控的速率延长的时间以产生局部或全身药理作用的药物递送装置包括：1.储存器，所述储存器包括：至少一种活性成分; 和至少一种药学上可接受的载体; 完全围绕储层的聚氨酯基聚合物。

3. 发明公开

EP2457564A1 Controlled release formulations of octreotide 审中-公开
标题翻译：奥曲肽控释制剂
公开(公告)号：EP2457564A1
公开(公告)日：2012-05-30
申请号：EP12156067.6
申请日：2006-03-10
申请人： Endo Pharmaceuticals Solutions Inc.
发明人： Kuzma, Petr , Decker, Stephanie
IPC分类号： A61K9/50 , A61K38/31 , A61K9/52
CPC分类号： A61K38/31 , A61K9/0024 , A61K47/32
摘要： A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two months. Methods of treating acromegaly, decreasing growth hormone, decreasing IGF-1, and treating conditions associated with carcinoid tumors and VIPomas by administering a controlled release formulation of octreotide are provided herein.

4. 发明公开

EP1982695A3 Manufacture of long term drug delivery devices with polyurethane 审中-公开
标题翻译：生产设备进行长期的药物供应聚氨酯
公开(公告)号：EP1982695A3
公开(公告)日：2010-05-26
申请号：EP08010973.9
申请日：2004-08-11
申请人： Endo Pharmaceuticals Solutions Inc.
发明人： Kuo, Sheng-hung , Kuzma, Petr
IPC分类号： A61K9/00
CPC分类号： A61L31/10 , A61K9/0024 , A61K9/0092 , A61L27/54 , A61M5/14 , B65B3/003 , Y10T29/49826
摘要： This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises: 1. a reservoir, said reservoir comprising; 2. at least one active ingredient; and, optionally, 3. at least one pharmaceutically acceptable carrier; a polyurethane based polymer completely surrounding the reservoir.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式