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1. 发明申请

US20110275637A1 PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS 审中-公开
标题翻译：哌嗪衍生物及其作为受体调节剂的使用
公开(公告)号：US20110275637A1
公开(公告)日：2011-11-10
申请号：US12996614
申请日：2009-06-04
申请人： Emma Chapman , Michael Higginbottom , Viet-Anh Anne Horgan (nee Nguyen) , James Horton , Iain Simpson , Charles Tyzack
发明人： Emma Chapman , Michael Higginbottom , Viet-Anh Anne Horgan (nee Nguyen) , James Horton , Iain Simpson , Charles Tyzack
IPC分类号： A61K31/5377 , C07D401/12 , A61K31/4439 , A61K31/496 , A61K31/4545 , A61P3/04 , A61P3/10 , A61P5/50 , A61P3/00 , A61P3/06 , A61P1/16 , A61P5/02 , A61P9/12 , A61P7/00 , A61P15/08 , A61P17/00 , A61P15/00 , A61P37/04 , A61P29/00 , A61P9/10 , C07D413/12
CPC分类号： C07D213/30 , C07D213/40 , C07D401/12 , C07D413/12
摘要： The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译：本发明涉及新的式（I）化合物，包含这些化合物的药物组合物以及这些化合物作为瘦素受体调节剂模拟物在制备与增重，2型糖尿病和血脂异常相关的病症的药物中的用途。

2. 发明申请

US20110275678A1 New Pyridine Derivatives as Leptin Receptor Modulator Mimetics 审中-公开
标题翻译：新型吡啶衍生物作为瘦蛋白受体调节剂模拟物
公开(公告)号：US20110275678A1
公开(公告)日：2011-11-10
申请号：US12996619
申请日：2009-06-04
申请人： Michael Higginbottom , Anne Viet-Anh Horgan (nee Nguyen) , James Horton , Iain Simpson , Charles Tyzack
发明人： Michael Higginbottom , Anne Viet-Anh Horgan (nee Nguyen) , James Horton , Iain Simpson , Charles Tyzack
IPC分类号： A61K31/4439 , C07D405/12 , C07D413/12 , A61K31/4409 , A61K31/443 , A61P3/10 , A61P3/06 , A61P5/48 , A61P3/00 , A61P1/16 , A61P5/02 , A61P9/12 , A61P7/00 , A61P15/08 , A61P17/00 , A61P25/00 , A61P15/00 , A61P37/00 , A61P29/00 , A61P9/10 , A61P3/04 , C07D213/55
CPC分类号： C07D213/30 , C07D405/12 , C07D413/12
摘要： The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译：本发明涉及新的式（I）化合物，包含这些化合物的药物组合物以及这些化合物作为瘦素受体调节剂模拟物在制备与增重，2型糖尿病和血脂异常相关的病症的药物中的用途。

3. 发明申请

US20070143578A1 System and method for message passing fabric in a modular processor architecture 审中-公开
标题翻译：在模块化处理器架构中消息传递结构的系统和方法
公开(公告)号：US20070143578A1
公开(公告)日：2007-06-21
申请号：US10579085
申请日：2004-11-12
申请人： James Horton , Robert Klein Jr. , George Gross , Terry Flemming , Reynolds Jenkins Jr.
发明人： James Horton , Robert Klein Jr. , George Gross , Terry Flemming , Reynolds Jenkins Jr.
IPC分类号： G06F15/00
CPC分类号： G06F15/16 , H04L49/1507 , H04L49/35
摘要： The invention provides a system and method of providing a message passing fabric in a modular processing system where a plurality of processing elements (VFBs), access other available processing elements to provide a message passing fabric where the fabric asynchronously establishes routes for synchronous messages from an origin processing element to a destination processing element to permit an operation to occur at the destination processing element in a flexible, efficient, self-routing and real-time dynamically optimized manner.
摘要翻译：本发明提供了一种在模块化处理系统中提供消息传递结构的系统和方法，其中多个处理元件（VFB）访问其他可用处理元件以提供消息传递结构，其中该结构异步地为原始处理元件到目的地处理元件，以允许以灵活，有效，自路由和实时动态优化的方式在目的地处理元件上进行操作。

4. 发明授权

US5018844A Passive beam derotator 失效
标题翻译：无源光束解旋器
公开(公告)号：US5018844A
公开(公告)日：1991-05-28
申请号：US457469
申请日：1989-12-27
申请人： James Horton
发明人： James Horton
IPC分类号： B23K26/02 , G02B17/02 , G02B27/64
CPC分类号： G02B17/02 , B23K26/042 , G02B27/642
摘要： A beam positioning system having two articulated arms with a pentaprism, or equivalent 90 degree prism, and a rotator prism, such as a Pechan prism, appropriately located in the path of a beam from a light source in combination with right angle prisms to maintain the final leg of the beam in orientation with the original orientation of the beam from the light source.
摘要翻译：一种光束定位系统，具有具有五棱镜或等效的90度棱镜的两个关节臂和诸如Pechan棱镜的旋转棱镜，其适当地位于来自光源的光束与直角棱镜组合的路径中，以保持梁的最后一个方向与来自光源的光束的原始取向成正比。

5. 发明授权

US4184265A Thread gage 失效
标题翻译：螺纹规
公开(公告)号：US4184265A
公开(公告)日：1980-01-22
申请号：US868986
申请日：1978-01-12
申请人： James Horton
发明人： James Horton
IPC分类号： G01B5/14 , G01B5/16 , G01B21/16 , G01B21/20 , G01B3/38
CPC分类号： G01B5/163 , G01B5/14
摘要： A thread gaging tool having a clamp member for rigidly clamping to a pipe end includes an axially sliding assembly coupled to a linear computer input transducer and supporting a pivoted arm provided with a gage pin which is inserted into the pipe thread to precisely measure the distance of each thread wall from the pipe end.
摘要翻译：具有用于刚性地夹紧到管端的夹紧构件的线程测量工具包括轴向滑动组件，其联接到线性计算机输入换能器并且支撑设置有插入管螺纹的定位销的枢转臂，以精确地测量距离每个螺纹壁从管端。

6. 发明申请

US20050257214A1 NON-INVASIVE AUTOMATIC OFFSITE PATCH FINGERPRINTING AND UPDATING SYSTEM AND METHOD 有权
标题翻译：非侵入式自动离线贴装指纹和更新系统及方法
公开(公告)号：US20050257214A1
公开(公告)日：2005-11-17
申请号：US11160439
申请日：2005-06-23
申请人： Sean Moshir , Christopher Andrew , Jack Hudler , Leon Li , Jonathan Gordon , Michael Bacon , Noah Williams , Jonathan Lane , James Horton , Dan Ferguson
发明人： Sean Moshir , Christopher Andrew , Jack Hudler , Leon Li , Jonathan Gordon , Michael Bacon , Noah Williams , Jonathan Lane , James Horton , Dan Ferguson
IPC分类号： G06F9/445 , G06F9/44
CPC分类号： G06F11/1433 , G06F8/62 , G06F8/65
摘要： Methods, systems, and configured storage media are provided for discovering software updates, discovering if a given computer can use the software update, and then updating the computers with the software as needed automatically across a network without storing the updates on an intermediate machine within the network. Furthermore, when a failure is detected, the rollout is stopped and the software can be automatically removed from those computers that already were updated. The software update can be stored originally at an address that is inaccessible through the network firewall by intermediately uploading the software update to an update computer which is not a part of the network but has access through the firewall, which is then used to distribute the update.
摘要翻译：提供了方法，系统和配置的存储介质，用于发现软件更新，发现给定的计算机是否可以使用软件更新，然后根据需要通过网络自动更新计算机，而无需将更新存储在内部的中间机器上网络。此外，当检测到故障时，卷动停止，软件可以自动从已更新的计算机中删除。软件更新可以最初存储在通过网络防火墙无法访问的地址，通过将软件更新上传到不是网络的一部分但可以通过防火墙访问的更新计算机，然后将其用于分发更新。

7. 发明申请

US20050203447A1 Waterproof hydrotherapy limb massager 审中-公开
标题翻译：防水水疗肢体按摩器
公开(公告)号：US20050203447A1
公开(公告)日：2005-09-15
申请号：US11075196
申请日：2005-03-08
申请人： Robert Pisani , James Horton
发明人： Robert Pisani , James Horton
IPC分类号： A61H9/00 , A61H23/04 , A61H37/00
CPC分类号： A61H9/00 , A61H9/0007 , A61H9/0071 , A61H23/04 , A61H2201/1669 , A61H2205/06
摘要： A hydrotherapy massage apparatus for the limbs of a patient having a water-tight chamber and a limb-receiving and surrounding waterproof, flexible sleeve extending longitudinally through an opening in the front wall of the chamber for insertion of the limb to be massaged into the chamber. At least one continuous hollow water head surrounds the sleeve and has opposed, peripherally spaced apart openings facing the sleeve through which water jets may be directed upon peripherally spaced apart portions of the limb within the sleeve.
摘要翻译：一种用于患者肢体的水疗按摩装置，具有不透水室和肢体接收和周围的防水柔性套管，其纵向延伸穿过腔室前壁中的开口，用于插入待按摩的肢体进入腔室。至少一个连续的中空水头围绕套筒并且具有面向套筒的相对的周向间隔开的开口，通过该套筒可以将水射流引导到套管内肢体的周向间隔开的部分。

8. 发明授权

US5893232A Natural bait holding fishing lure 失效
标题翻译：天然诱饵捕鱼诱饵
公开(公告)号：US5893232A
公开(公告)日：1999-04-13
申请号：US933512
申请日：1997-09-18
申请人： Robert Horton , James Horton , David K. Matsunaga
发明人： Robert Horton , James Horton , David K. Matsunaga
IPC分类号： A01K83/06
CPC分类号： A01K83/06
摘要： The present invention is a natural bait holding fishing lure, available in multiple sizes, to use with dead bait fish and/or dew worms. This minnow head shaped lure is preferably molded from resin plastic and includes a rod for the trailer model, or tube for the pull-through model, to impale the bait as it is inserted head first into the cavity of the lure. Also connected to the lure is a pivoting L shaped barbed locking pin device, and a metal foil which deflects water to simulate the swimming motion of a live minnow when trolled through the water with the bait attached, and thus promotes attraction of the target fish.
摘要翻译：本发明是一种具有钓鱼诱饵的天然诱饵，具有多种尺寸，可与死饵鱼和/或露蚯蚓一起使用。这种稚鱼头状诱饵优选地由树脂塑料模制，并且包括用于拖车模型的杆或用于拉直模型的管，当诱饵首先插入诱饵的空腔中时，将饵料刺入。还连接诱饵是一个旋转的L形倒钩锁定销装置，以及一个金属箔，当金属饵连接时，通过水溜出来，使水流偏转，模拟活鲤鱼的游泳运动，从而促进目标鱼的吸引。

9. 发明授权

US5121989A Transportable concrete batching apparatus 失效
标题翻译：运输混凝土搅拌设备
公开(公告)号：US5121989A
公开(公告)日：1992-06-16
申请号：US491498
申请日：1990-03-12
申请人： James Horton , Ronald E. Christenson , Tim Irwin
发明人： James Horton , Ronald E. Christenson , Tim Irwin
IPC分类号： B28C9/04
CPC分类号： B28C9/0418
摘要： A transportable concrete batching plant is disclosed which combines improvements in the discharge section of the aggregate storage bin and aggregate batching hopper together with an unique suspension system which allows for weighing of both aggregate batching hopper and the cement batching vessel by a plurality of load cells and which also allows tension to be removed from the load cells if desired.
摘要翻译：公开了一种运输混凝土搅拌站，其结合了集料储存箱和集料分料斗的排出部分的改进以及独特的悬挂系统，其允许通过多个称重传感器对集料分批料斗和水泥配料容器进行称重，如果需要，这也允许从称重传感器去除张力。

10. 发明授权

US06954429B2 Bandwidth control system 失效
标题翻译：带宽控制系统
公开(公告)号：US06954429B2
公开(公告)日：2005-10-11
申请号：US09826235
申请日：2001-04-04
申请人： James Horton , Lois Hollopeter , Victor Nunes , Scott Searcy , David Thomas
发明人： James Horton , Lois Hollopeter , Victor Nunes , Scott Searcy , David Thomas
IPC分类号： H04J3/16 , H04L12/24 , H04L12/56 , G06F11/00 , H04L12/26
CPC分类号： H04L47/24 , H04J3/1682 , H04L41/0896 , H04L41/12 , H04L47/10 , H04L47/22
摘要： A bandwidth control system for a network, the network having a host computer that includes a first network interface and a second network interface. A packet driver adapted to be executed on the host computer is logically connected to the first network interface and the second network interface. The packet driver captures packets received from the network on the first network interface. A traffic shaper adapted to be executed on the host computer maintains a topology representation of the network, the topology representation including one or more nodes. The traffic shaper performs priority and packet rate metering functions on the captured packets to match a set of rate conditions unique to each node in the topology representation of the network. The captured packets are returned to the packet driver for transmission to the network on the second network interface.
摘要翻译：一种用于网络的带宽控制系统，所述网络具有包括第一网络接口和第二网络接口的主计算机。适于在主计算机上执行的分组驱动器逻辑上连接到第一网络接口和第二网络接口。数据包驱动程序捕获在第一个网络接口上从网络接收的数据包。适于在主计算机上执行的流量整形器维护网络的拓扑表示，拓扑表示包括一个或多个节点。流量整形器对捕获的分组执行优先级和分组速率计量功能，以匹配网络的拓扑表示中每个节点唯一的一组速率条件。所捕获的分组被返回到分组驱动器，以在第二网络接口上传送到网络。

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