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1. 发明申请

US20090018427A1 ELECTRODE ARRAY 有权
标题翻译：电极阵列
公开(公告)号：US20090018427A1
公开(公告)日：2009-01-15
申请号：US12067525
申请日：2006-09-22
申请人： Elvir Causevic , Christian Christiansen , Daniel Metzger
发明人： Elvir Causevic , Christian Christiansen , Daniel Metzger
IPC分类号： A61B5/04
CPC分类号： A61B5/04845 , A61B5/0478 , A61B5/6803 , A61B5/6814 , A61B2562/164
摘要： A disposable electrode array 100, 200 including a flexible member 106, 206 in which a plurality of electrodes 102, 202 are disposed, having a shape adapted to contact the forehead skin surface on a human patient. A pair of ear loops 104, 204 coupled to the disposable electrode array 100, 200 secure the disposable electrode array 100, 200 about the patient's ears, with the flexible member 106, 206 disposed across the patient's bow, retaining the electrodes 102, 202 against the skin surface. Additional electrodes 102, 202 are disposed in proximity to the ear loops 104, 204 and are configured to contact the skin surface behind the patient's ears. An auditory stimulus delivery element 116, 216 is coupled with each of the ear loops 104, 204, and positioned to seat in proximity to the patient's ear canal for the delivery of auditory stimulus. Electrical conductors associated with the electrodes 102, 202 and the stimulus delivery elements 116, 216 are routed within the flexible member 106, 206 to a common external connection point 118, 218 for connection to an external system. The disposable electrode array 100, 200 may be configured for both evoking and measuring evoked bio-potentials in the human subject, or for measuring bio-potentials evoked using a separate stimulus delivery system.
摘要翻译：包括柔性构件106,206的一次性电极阵列100,200，其中设置有多个电极102,202，其具有适于接触人类患者的前额皮肤表面的形状。耦合到一次性电极阵列100,200的一对耳环104,204将患者耳朵周围的一次性电极阵列100,200固定在一起，使柔性构件106,206跨过病人的弓状物设置，保持电极102,202抵抗皮肤表面。附加电极102,202设置在耳环104,204附近，并被配置为接触患者耳朵后面的皮肤表面。听觉刺激传递元件116,216与耳环104,204中的每一个耦合，并被定位成靠近患者的耳道以便传送听觉刺激。与电极102,202和刺激递送元件116,216相关联的电导体在柔性构件106,206内被路由到共同的外部连接点118,218以连接到外部系统。一次性电极阵列100,200可以被配置用于唤醒和测量人类受试者中的诱发生物电位，或者用于测量使用单独的刺激递送系统诱发的生物电位。

2. 外观设计

USD594127S1 Electrode array 有权
标题翻译：电极阵列
公开(公告)号：USD594127S1
公开(公告)日：2009-06-09
申请号：US29298138
申请日：2007-11-29
申请人： Elvir Causevic , Christian Christiansen , Daniel Metzger , Greg Holderfield , Elliot Hsu
设计人： Elvir Causevic , Christian Christiansen , Daniel Metzger , Greg Holderfield , Elliot Hsu

3. 外观设计

USD560809S1 Electrode array 有权
标题翻译：电极阵列
公开(公告)号：USD560809S1
公开(公告)日：2008-01-29
申请号：US29238840
申请日：2005-09-22
申请人： Elvir Causevic , Christian Christiansen , Daniel Metzger , Greg Holderfield , Elliott Hsu
设计人： Elvir Causevic , Christian Christiansen , Daniel Metzger , Greg Holderfield , Elliott Hsu

4. 发明授权

US08391948B2 Electrode array 有权
标题翻译：电极阵列
公开(公告)号：US08391948B2
公开(公告)日：2013-03-05
申请号：US12067525
申请日：2006-09-22
申请人： Elvir Causevic , Christian Christiansen , Daniel Metzger
发明人： Elvir Causevic , Christian Christiansen , Daniel Metzger
IPC分类号： A61B5/0478 , A61B5/0484
CPC分类号： A61B5/04845 , A61B5/0478 , A61B5/6803 , A61B5/6814 , A61B2562/164
摘要： A disposable electrode array 100, 200 including a flexible member 106, 206 in which a plurality of electrodes 102, 202 are disposed, having a shape adapted to contact the forehead skin surface on a human patient. A pair of ear loops 104, 204 coupled to the disposable electrode array 100, 200 secure the disposable electrode array 100, 200 about the patient's ears, with the flexible member 106, 206 disposed across the patient's bow, retaining the electrodes 102, 202 against the skin surface. Additional electrodes 102, 202 are disposed in proximity to the ear loops 104, 204 and are configured to contact the skin surface behind the patient's ears. An auditory stimulus delivery element 116, 216 is coupled with each of the ear loops 104, 204, and positioned to seat in proximity to the patient's ear canal for the delivery of auditory stimulus. Electrical conductors associated with the electrodes 102, 202 and the stimulus delivery elements 116, 216 are routed within the flexible member 106, 206 to a common external connection point 118, 218 for connection to an external system. The disposable electrode array 100, 200 may be configured for both evoking and measuring evoked bio-potentials in the human subject, or for measuring bio-potentials evoked using a separate stimulus delivery system.
摘要翻译：包括柔性构件106,206的一次性电极阵列100,200，其中设置有多个电极102,202，其具有适于接触人类患者的前额皮肤表面的形状。耦合到一次性电极阵列100,200的一对耳环104,204将患者耳朵周围的一次性电极阵列100,200固定在一起，使柔性构件106,206跨过病人的弓状物设置，保持电极102,202抵抗皮肤表面。附加电极102,202设置在耳环104,204附近，并被配置为接触患者耳朵后面的皮肤表面。听觉刺激传递元件116,216与耳环104,204中的每一个耦合，并被定位成靠近患者的耳道以便传送听觉刺激。与电极102,202和刺激递送元件116,216相关联的电导体在柔性构件106,206内被路由到共同的外部连接点118,218以连接到外部系统。一次性电极阵列100,200可以被配置用于唤醒和测量人类受试者中的诱发生物电位，或者用于测量使用单独的刺激递送系统诱发的生物电位。

5. 发明申请

US20100185115A1 APPARATUS FOR EVOKING AND RECORDING BIO-POTENTIALS 审中-公开
标题翻译：用于检测和记录生物活性的装置
公开(公告)号：US20100185115A1
公开(公告)日：2010-07-22
申请号：US12710603
申请日：2010-02-23
申请人： Elvir Causevic , Christian Christiansen , Eldar Causevic
发明人： Elvir Causevic , Christian Christiansen , Eldar Causevic
IPC分类号： A61B5/0484
CPC分类号： A61B5/0482 , A61B5/0484 , A61B5/04845 , A61B5/04847 , A61B5/6815 , A61B5/6838
摘要： Apparatus (10) for evoking and recording bio-potentials from a human subject and methods of use are described. The apparatus (10) includes a flexible member (18) with a layer of conductive material (12) disposed thereon for contacting a skin surface on the human subject. The dimensions and shape of the flexible member (18) are adapted for conforming contact between the conductive material (12) and the skin surface. A stimulus delivery element (28) is coupled to the flexible member (18) for delivering a sensory stimulus to the subject to evoke bio-potentials, which are detected and received through the layer of conductive material (12).
摘要翻译：描述了用于从人类受试者唤起和记录生物潜力的装置（10）和使用方法。该设备（10）包括柔性构件（18），其上设置有用于接触人体对象皮肤表面的导电材料层（12）。柔性构件（18）的尺寸和形状适于使导电材料（12）与皮肤表面之间的接触一致。刺激递送元件（28）耦合到柔性构件（18），用于将感觉刺激传递给受试者，以引起通过导电材料层（12）检测和接收的生物电位。

6. 发明申请

US20070167694A1 Integrated Portable Anesthesia and Sedation Monitoring Apparatus 审中-公开
标题翻译：综合便携式麻醉和镇静监测仪
公开(公告)号：US20070167694A1
公开(公告)日：2007-07-19
申请号：US11614582
申请日：2006-12-21
申请人： Elvir Causevic , Robert Hedges , Randall Krohn , Christian Christiansen , Ralph Walden
发明人： Elvir Causevic , Robert Hedges , Randall Krohn , Christian Christiansen , Ralph Walden
IPC分类号： A61B5/00 , A61B5/04 , A61B5/08
CPC分类号： A61B5/4064 , A61B5/024 , A61B5/0402 , A61B5/0404 , A61B5/0476 , A61B5/04845 , A61B5/08 , A61B5/082 , A61B5/14542 , A61B5/1455 , A61B5/411 , A61B5/4821 , A61B5/7203 , A61B5/726 , A61B2562/08
摘要： A system and method for performing monitoring of anesthesia and sedation in a patient includes a patient sensor integrating EEG, pulse oximetry, ECG, and AEP signal inputs, integrated analog hardware, digital hardware, and a digital signal processing system that executes a selected algorithm to process received signals representative of a patient's condition, and which generates an index value associated with said patient condition.
摘要翻译：用于执行患者麻醉和镇静监测的系统和方法包括将EEG，脉搏血氧饱和度测量，ECG和AEP信号输入集成的综合模拟硬件，数字硬件和执行所选算法的数字信号处理系统的患者传感器处理接收到的代表患者状况的信号，并产生与所述患者状况相关联的指标值。

7. 发明申请

US20060217632A1 Apparatus for evoking and recording bio potentials 审中-公开
标题翻译：用于诱发和记录生物潜力的装置
公开(公告)号：US20060217632A1
公开(公告)日：2006-09-28
申请号：US10545221
申请日：2003-02-10
申请人： Elvir Causevic , Christian Christiansen , Eldar Causevic
发明人： Elvir Causevic , Christian Christiansen , Eldar Causevic
IPC分类号： A61B5/00 , A61B19/00 , A61B13/00
CPC分类号： A61B5/0482 , A61B5/0484 , A61B5/04845 , A61B5/04847 , A61B5/6815 , A61B5/6838
摘要： Apparatus (10) for evoking and recording bio-potentials from a human subject and methods of use are described. The apparatus (10) includes a flexible member (18) with a layer of conductive material (12) disposed thereon for contacting a skin surface on the human subject. The dimensions and shape of the flexible member (18) are adapted for conforming contact between the conductive material (12) and the skin surface. A stimulus delivery element (28) is coupled to the flexible member (18) for delivering a sensory stimulus to the subject to evoke bio-potentials, which are detected and received through the layer of conductive material (12).
摘要翻译：描述了用于从人类受试者唤起和记录生物潜力的装置（10）和使用方法。该设备（10）包括柔性构件（18），其上设置有用于接触人体对象皮肤表面的导电材料层（12）。柔性构件（18）的尺寸和形状适于使导电材料（12）与皮肤表面之间的接触一致。刺激递送元件（28）耦合到柔性构件（18），用于将感觉刺激传递给受试者，以引起通过导电材料层（12）检测和接收的生物电位。

8. 发明申请

US20180165605A1 MACHINE LEARNING-BASED PATENT QUALITY METRIC 审中-公开
公开(公告)号：US20180165605A1
公开(公告)日：2018-06-14
申请号：US15837652
申请日：2017-12-11
申请人： Matthew Beers , Elvir Causevic
发明人： Matthew Beers , Elvir Causevic
IPC分类号： G06N99/00 , G06K9/62 , G06K9/00 , G06N5/04
CPC分类号： G06N20/00 , G06K9/00442 , G06K9/6227 , G06K9/626 , G06K9/6262 , G06K9/6277 , G06N3/0454 , G06N3/086 , G06N5/043
摘要： A machine-learning based artificial intelligence device for finding an estimate of patent quality, such as patent lifetime or term is disclosed. Such a device may receive a first set of patent data and generate a list of binary classifiers. A candidate set of binary classifiers may be selected and using a heuristic search, for example an artificial neural network (ANN), a genetic algorithm, a final set of binary classifiers is found by maximizing iteratively a yield according to a cost function, such an area under a curve (AUC) of a receiver operating characteristic (ROC). The device may then receive patent information for a target patent and report an estimate of patent quality according to the final set of binary classifiers.

9. 发明授权

US07333619B2 Fast wavelet estimation of weak bio-signals using novel algorithms for generating multiple additional data frames 有权
标题翻译：使用用于生成多个附加数据帧的新算法对弱生物信号进行快速小波估计
公开(公告)号：US07333619B2
公开(公告)日：2008-02-19
申请号：US11420862
申请日：2006-05-30
申请人： Elvir Causevic , Eldar Causevic , Mladen Victor Wickerhauser
发明人： Elvir Causevic , Eldar Causevic , Mladen Victor Wickerhauser
IPC分类号： H04B15/00 , G10L21/02 , G10L19/14
CPC分类号： G06K9/00516 , A61B5/04845 , A61B5/121 , A61B5/7203 , A61B5/726 , G10L21/0208 , G10L25/27 , H03G3/007
摘要： A method and apparatus for de-noising weak bio-signals having a relatively low signal to noise ratio utilizes an iterative process of wavelet de-noising a data set comprised of a new set of frames of wavelet coefficients partially generated through a cyclic shift algorithm. The method preferably operates on a data set having 2N frames, and the iteration is performed N−1 times. The resultant wavelet coefficients are then linearly averaged and an inverse discrete wavelet transform is performed to arrive at the de-noised original signal. The method is preferably carried out in a digital processor.
摘要翻译：用于消除具有相对低的信噪比的弱生物信号的方法和装置利用小波去噪的迭代过程，该数据集包括通过循环移位算法部分产生的新的一组小波系数。该方法优选地对具有2个N帧的数据集进行操作，并且迭代被执行N-1次。然后对所得到的小波系数进行线性平均，并执行逆离散小波变换以得到去噪的原始信号。该方法优选在数字处理器中进行。

10. 发明申请

US20070167857A1 Method and apparatus for signal encoding evoked responses 有权
标题翻译：用于信号编码诱发响应的方法和装置
公开(公告)号：US20070167857A1
公开(公告)日：2007-07-19
申请号：US10587461
申请日：2005-01-28
申请人： Elvir Causevic
发明人： Elvir Causevic
IPC分类号： A61B5/04 , A61B13/00 , A61B5/00
CPC分类号： A61B5/125 , A61B5/0048 , A61B5/04842 , A61B5/04845 , A61B5/742
摘要： A method and apparatus for utilizing the benefits of encoded signal transmission and reception to enhance the performance of medical testing devices (100) adapted to evoke and measure biological response signals such as auditory evoked potentials (AEP), and the auditory brainstem response (ABR) signals in particular. Auditory stimuli, such as clicks, are presented to the ear of a human patient, in a predetermined encoded sequence, resulting in the generation of auditory responses and bio-electric response signals in the human patient. These response signals from the patient are acquired and observed, and are processed according to the predetermined encoded sequence in which the auditory stimuli were presented to the patient's ear in order to extract the desired auditory evoked potential signals or ABR signals.
摘要翻译：一种用于利用编码信号传输和接收的益处来增强适于唤起和测量例如听觉诱发电位（AEP）和听觉脑干响应（ABR）的生物反应信号的医学测试装置（100）的性能的方法和装置，信号特别。诸如点击的听觉刺激以预定编码序列呈现给人类患者的耳朵，导致在人类患者中产生听觉反应和生物电响应信号。获取并观察来自患者的这些响应信号，并且根据将听觉刺激呈现给患者耳朵的预定编码序列进行处理，以便提取期望的听觉诱发电位信号或ABR信号。

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