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2. 发明申请

US20120274925A1 Axial light loss sensor system for flow cytometery 审中-公开
标题翻译：用于流式细胞术的轴向光损失传感器系统
公开(公告)号：US20120274925A1
公开(公告)日：2012-11-01
申请号：US13456033
申请日：2012-04-25
申请人： Yong Chen , David W. Houck
发明人： Yong Chen , David W. Houck
IPC分类号： G01N21/59 , G01N21/53
CPC分类号： G01N21/534 , G01N15/1434 , G01N15/1459 , G01N15/147 , G01N21/59 , G01N2015/008 , G01N2015/1006 , G01N2015/145
摘要： An axial light loss sensor system, and methods for measuring axial light loss with improved resolution are provided. Aspects of the present invention include an axial light loss sensor positioned along an axis of irradiation to detect axial light loss resulting from a particle passing a light source intersect in a fluid stream, and an obstruction positioned along the axis of irradiation between the light source intersect and the axial light loss sensor. The obstruction is further positioned so as to have an on-axis opaque surface. The obstruction allows for the measurement of a fringe signal in a far-field with respect to the irradiated particle, in order to measure the axial light loss produced by the particle. The systems and methods described herein find use in, for example, flow cytometery.
摘要翻译：提供轴向光损失传感器系统，以及用于以改进的分辨率测量轴向光损失的方法。本发明的方面包括沿着照射轴定位的轴向光损失传感器，以检测通过光源在流体流中相交的颗粒所导致的轴向光损失，以及沿着光源相交的沿照射轴设置的障碍物和轴向光损失传感器。障碍物进一步定位成具有轴上不透明表面。障碍物允许测量相对于辐照颗粒的远场中的条纹信号，以便测量由颗粒产生的轴向光损失。本文所述的系统和方法可用于例如流式细胞术。

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