专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4616025A Thiazolidine derivatives, process for the preparation and pharmaceutical compositions thereof 失效
标题翻译：噻唑烷衍生物，制备方法及其药物组合物
公开(公告)号：US4616025A
公开(公告)日：1986-10-07
申请号：US590486
申请日：1984-03-16
申请人： Elemer Ezer , Kalman Harsanyi , Gyorgy Domany , Laszlo Szporny , Judit Matuz , Bela Hegedus , Katalin Pallagi , Istvan Szabadkai , Peter Tetenyi
发明人： Elemer Ezer , Kalman Harsanyi , Gyorgy Domany , Laszlo Szporny , Judit Matuz , Bela Hegedus , Katalin Pallagi , Istvan Szabadkai , Peter Tetenyi
IPC分类号： A61K31/425 , A61K31/426 , A61K31/427 , A61P1/04 , C07D277/10 , C07D277/18 , C07D307/52 , C07D417/06 , C07D417/14
CPC分类号： C07D417/06 , C07D277/10 , C07D277/18 , C07D307/52
摘要： New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: ##STR1## wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, halo-C.sub.1-4 -alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a group of the formula (II), ##STR2## wherein Y is nitrogen or CH;Z is cyano or carbamoyl if Y is nitrogen, and represents a nitro group if Y is CH.Also disclosed are several processes for preparing the new compounds as well as pharmaceutical compositions and method of treatment employing same.
摘要翻译：公开了具有抗溃疡活性的式（I）的新噻唑烷化合物：其中Ar是任选被一个或多个C 1-4 - 烷基取代的2-呋喃基或苯基，萘基或吡啶基， C 1-4 - 烷氧基，卤代C 1-4 - 烷氧基，二卤代甲基，三卤代甲基，羟基或硝基，或由式（II）的基团，其中Y是氮或CH; 如果Y是氮，Z是氰基或氨基甲酰基，如果Y是CH，则表示硝基。还公开了制备新化合物的几种方法以及使用其的药物组合物和治疗方法。

2. 发明授权

US5162359A Antihyperlipoproteinemic 5-benzyl substituted-benzimidazoline-2-thion derivatives 失效
标题翻译： 5-苯基取代苯并咪唑-2-基衍生物的抗高血压药物
公开(公告)号：US5162359A
公开(公告)日：1992-11-10
申请号：US753751
申请日：1991-09-03
申请人： Kalman Harsanyi , Peter Tetenyi , Tamas Nagy , Attila Csehi , Tibor Gizur , Bela Hegedus , Andrea Maderspach , Andras Javor , Gyorgy Hajos , Laszlo Szporny
发明人： Kalman Harsanyi , Peter Tetenyi , Tamas Nagy , Attila Csehi , Tibor Gizur , Bela Hegedus , Andrea Maderspach , Andras Javor , Gyorgy Hajos , Laszlo Szporny
IPC分类号： A61K31/425 , A61K31/4184 , A61P3/06 , A61P7/02 , A61P9/10 , C07D235/28
CPC分类号： C07D235/28
摘要： Novel antihyperlipoproteinemic compounds are disclosed of the formula I, ##STR1## wherein X is a halogen atom, methyl, ethyl, methoxy or ethoxy group,Y is hydroxy if X is methoxy or ethoxy, otherwise it is a hydrogen atom or a, methoxy or ethoxy group,Z is a methoxy or ethoxy group if X or Y is a methoxy group or an ethoxy group; otherwise it is hydrogen atom,The invention also covers antiartheriosclerotic, antihyperlipoproteinemic pharmaceutical compositions, suitable for inhibiting the formation of thrombuses, comprising the compounds of formula I in an effective dose, a process for preparing the same and methods for the treatment of hyperlipoproteinemia with the aid of the said compounds or compositions.
摘要翻译：公开了式I，其中X是卤素原子，甲基，乙基，甲氧基或乙氧基的式I，（I）的新型抗高脂蛋白化合物，如果X是甲氧基或乙氧基，则Y是羟基，否则它是氢原子或甲氧基或乙氧基，如果X或Y是甲氧基或乙氧基，Z是甲氧基或乙氧基; 本发明还包括适用于抑制血栓形成的抗肝硬化，抗高脂蛋白血症药物组合物，其包含有效剂量的式I化合物，其制备方法和用于治疗高脂蛋白血症的方法所述化合物或组合物的帮助。

3. 发明授权

US4814329A Antihyperlipoproteinemic 5-substituted sulfur-containing benzimidazole derivatives 失效
标题翻译：抗高脂蛋白血症5-取代含硫苯并咪唑衍生物
公开(公告)号：US4814329A
公开(公告)日：1989-03-21
申请号：US840424
申请日：1986-03-17
申请人： Kalmen Harsanyi , Andrea Maderspach , Andres Javor , Gyorgy Hajos , Gyorgy Fekete , Laslo Szporny , Peter Tetenyi , Katalin Csomor , Egon Karpati , Bela Hegedus , Marta Kapolnas nee Pap , Marta Szollosy , Anna Kallay nee Sohonyai
发明人： Kalmen Harsanyi , Andrea Maderspach , Andres Javor , Gyorgy Hajos , Gyorgy Fekete , Laslo Szporny , Peter Tetenyi , Katalin Csomor , Egon Karpati , Bela Hegedus , Marta Kapolnas nee Pap , Marta Szollosy , Anna Kallay nee Sohonyai
IPC分类号： A61K31/415 , A61K31/4184 , A61K31/445 , A61K31/454 , A61K31/535 , A61K31/5355 , A61K31/54 , A61K31/541 , A61P3/06 , C07D235/28 , C07D513/04 , A61K31/55 , C07D413/12 , C07D417/12
CPC分类号： C07D513/04 , C07D235/28
摘要： The invention relates to novel, sulfur-containing 5-substituted benzimidazole derivatives of formula I ##STR1## and acid-addition salts thereof antihyperlipoproteinemic action, a process for preparing the same, pharmaceutical formulations comprising the novel compound as active ingredient and a method for inhibiting atherosclerosis, trombus formation and treating hyperlipoproteinemic diseases.
摘要翻译：本发明涉及式I的新型含硫5-取代苯并咪唑衍生物及其酸加成盐抗高脂蛋白血症作用，其制备方法，包含该新化合物作为活性成分的药物制剂及其制备方法抑制动脉粥样硬化，血栓形成和治疗高脂蛋白血症。

4. 发明授权

US4591524A Chromatographic sheet of layer for pressurized layer chromatographic apparatus 失效
标题翻译：用于加压层色谱仪的色谱层
公开(公告)号：US4591524A
公开(公告)日：1986-05-27
申请号：US285090
申请日：1981-07-15
申请人： Erno Tyihak , Emil Mincsovics , Jozsef Knoll , Sandor Zoltan , Istvan Lak , Peter Tetenyi , Huba Kalasz , Janos Nagy
发明人： Erno Tyihak , Emil Mincsovics , Jozsef Knoll , Sandor Zoltan , Istvan Lak , Peter Tetenyi , Huba Kalasz , Janos Nagy
IPC分类号： G01N31/00 , G01N30/90 , G01N30/92 , G01N30/93 , G01N30/94 , B32B3/02 , B32B3/30
CPC分类号： G01N30/94 , G01N2030/906 , G01N30/90 , Y10T428/24314 , Y10T428/24322 , Y10T428/24331 , Y10T428/24488 , Y10T428/2457 , Y10T428/2462 , Y10T428/24777 , Y10T428/24793 , Y10T428/24843 , Y10T428/24926 , Y10T428/252
摘要： An adsorbent layer (stationary phase) for a pressurized layer chromatographic apparatus, for the development of linear chromatogram, is sealed at the edges by impregnation. For the purpose of solvent control some of the adsorbent material is removed in one or several zones of the adsorbent layer near the place of solvent admission, or one or several baffle plates or wires are arranged behind the place(s) of sample application, or if necessary, the adsorbent layer is provided with a conventionally formed concentration zone in the area of the solvent admission. As a result of the impregnation, the migrating solvent composite does not escape at the edges of the adsorbent layer according to the invention in case of overpressure. As a result of the removal of adsorbent material, or the arrangement of baffles or wires, or the application of a concentration zone, the solvent migrates with a straight-line front.
摘要翻译： PCT No.PCT / HU80 / 00006 Sec。 371日期1981年7月15日 102（e）日期1981年7月15日PCT提交1980年12月5日PCT公布。出版物WO81 / 01746 日期：1981年6月25日。用于开发线性色谱图的用于加压层色谱仪的吸附剂层（固定相）通过浸渍在边缘密封。为了溶剂控制的目的，一些吸附剂材料在吸附剂层的一个或几个区域中被吸附到溶剂进入位置附近，或者一个或多个挡板或导线布置在样品施加位置的后面，或如果需要，吸附剂层在溶剂入口区域中设置有常规形成的浓缩区。作为浸渍的结果，在超压的情况下，迁移溶剂复合材料在本发明的吸附剂层的边缘处不逸出。作为除去吸附剂材料或挡板或导线的布置或应用浓缩区的结果，溶剂以直线前沿迁移。

5. 发明授权

US5565214A Stable therapeutic oil filled soft gelatin capsules 失效
标题翻译：稳定的治疗油填充软明胶胶囊
公开(公告)号：US5565214A
公开(公告)日：1996-10-15
申请号：US96058
申请日：1993-07-22
申请人： Istvan Zambo , Erzsebet Szabo , Sandor Jancso , Gyorgy Vago , Bela Danos , Pal Kaposi , Peter Tetenyi , Gyorgy Bacsa , Zsuzsanna Emri , Zoltan Gombos
发明人： Istvan Zambo , Erzsebet Szabo , Sandor Jancso , Gyorgy Vago , Bela Danos , Pal Kaposi , Peter Tetenyi , Gyorgy Bacsa , Zsuzsanna Emri , Zoltan Gombos
IPC分类号： A23D9/007 , A61K9/48 , A61K31/23 , A61K35/60 , A61K36/00 , A61K36/18 , A61K36/185 , A61K36/28 , A61K36/30 , A61K36/42 , A61K36/896 , A61K36/8962 , A61K36/899
CPC分类号： A61K9/4858 , A61K35/60 , A61K36/185 , A61K36/28 , A61K36/30 , A61K36/42 , A61K36/752 , A61K36/8962 , A61K36/899 , Y10S514/962
摘要： The invention relates to a process for the preparation of therapeutically useful, highly stable soft gelatine capsules containing native oils obtained in the case of vegetable oils by the cold pressing of mainly plant parts, such as seeds, which comprises adjusting the free fatty acid content of the oil to an acid number of from about 0.3 to about 4.5 by mixing oils of identical or different natural source with a different acid number not in excess of about 4.5 and then filling the oil into soft gelatine capsules aromatized from about 0% to about 10% by mass of a perfume.
摘要翻译：本发明涉及一种用于制备治疗有用的，高度稳定的软明胶胶囊的方法，所述软明胶胶囊含有在植物油的情况下通过主要植物部分如种子的冷压获得的天然油，其包括调节游离脂肪酸含量通过将相同或不同的天然来源的油与不超过约4.5的不同酸值混合，然后将油充填到由约0％至约10％芳族化的软明胶胶囊中，将油变为约0.3至约4.5的酸值质量％的香料。

6. 发明授权

US4272276A Method for the control of germination of plant seeds and growth of the seedlings 失效
标题翻译：控制植物种子萌发和幼苗生长的方法
公开(公告)号：US4272276A
公开(公告)日：1981-06-09
申请号：US040957
申请日：1979-05-21
申请人： Jozsef Szejtli , Magda Tetenyi nee Erdosi , Peter Tetenyi
发明人： Jozsef Szejtli , Magda Tetenyi nee Erdosi , Peter Tetenyi
IPC分类号： A01N43/14 , A01N31/00 , A01N43/16 , A01P21/00
CPC分类号： A01N43/16
摘要： A method of controlling seed germination and growth of the seedlings which comprises contacting plant seeds with a liquid or solid dextrin.
摘要翻译：控制种子发芽和幼苗生长的方法，其包括使植物种子与液体或固体糊精接触。

7. 发明授权

US4923853A Process for enhancing the activity of plant protecting agents by using cyclodextrin 失效
标题翻译：通过使用环糊精增强植物保护剂活性的方法
公开(公告)号：US4923853A
公开(公告)日：1990-05-08
申请号：US218466
申请日：1988-07-11
申请人： Jozsef Szejtli , Peter Tetenyi , Marta Kiniczky , Jeno Bernath , Magda Tetenyi nee Erdosi , Eva Dobos , Erzsebet Banky nee Elod
发明人： Jozsef Szejtli , Peter Tetenyi , Marta Kiniczky , Jeno Bernath , Magda Tetenyi nee Erdosi , Eva Dobos , Erzsebet Banky nee Elod
IPC分类号： A01N25/22 , A01N25/10 , A01N43/90 , A01N47/18 , A01N47/38 , A01N63/00
CPC分类号： A01N47/18 , A01N25/10 , A01N43/90 , A01N47/38
摘要： The invention relates to fungicidal plant protecting composition comprising 3-90% by weight of a fungicidal active ingredient in admixture with 1-90% by weight of cyclodextrin and optionally with usual auxiliary agents.The advantage of the synergistic composition of the present invention is that identical fungicidal effect can be achieved with a significantly lower active ingredient dosage and this decreases the costs involved with the active ingredient and reduces the risks of environmental pollution as well.
摘要翻译：本发明涉及杀真菌植物保护组合物，其包含3-90重量％的杀真菌活性成分与1-90重量％的环糊精和任选的常用助剂混合。本发明的协同组合物的优点是可以以显着降低的活性成分剂量实现相同的杀真菌作用，并且降低了活性成分所涉及的成本并降低了环境污染的风险。

8. 发明授权

US4746678A Phenanthrene derivatives 失效
标题翻译：菲衍生物
公开(公告)号：US4746678A
公开(公告)日：1988-05-24
申请号：US870402
申请日：1986-06-04
申请人： Pal Benko , Tibor Zsolnai , Marta Kininczky , Laszlo Pallos , Iren Zsolnai nee Csillag , Peter Tetenyi , Jeno Bernath
发明人： Pal Benko , Tibor Zsolnai , Marta Kininczky , Laszlo Pallos , Iren Zsolnai nee Csillag , Peter Tetenyi , Jeno Bernath
IPC分类号： A61K31/265 , A01N37/16 , A01N37/34 , A01N37/38 , A01N37/44 , A01N37/48 , A01N47/06 , A01N47/24 , A61K31/27 , A61K31/275 , A61P31/04 , C07C67/00 , C07C249/12 , C07C251/44 , C07C325/00 , C07C329/06 , A61K31/15
CPC分类号： A01N47/06 , A01N37/16 , A01N47/24 , C07C2103/26
摘要： The invention relates to new phenanthrene derivatives wherein R stand for C.sub.1-10 alkylamino; C.sub.1-10 alkylthio; C.sub.1-5 alkoxy; or phenyl or phenylamino, the two latter groups being optionally substituted on the phenyl ring by one or more identical or different C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro, amino, cyano and/or halogen substituent(s) .The compounds of the present invention possess valuable fungicidal properties and may be used in agriculture, horticulture and therapy as active ingredient of fungicidal or antifungal compositions.The compounds of the general Formula I ##STR1## may be prepared by acylating 9,10-phenanthrene-dione-9-oxime or an alkali or alkali earth metal salt thereof.
摘要翻译：本发明涉及新的菲衍生物，其中R代表C1-10烷基氨基; C 1-10烷硫基; C 1-5烷氧基或苯基或苯基氨基，后两个基团在苯环上任选被一个或多个相同或不同的C 1-4烷基，C 1-4烷氧基，硝基，氨基，氰基和/或卤素取代基取代。本发明的化合物具有有价值的杀真菌性质，可用作农业，园艺和治疗用作杀真菌剂或抗真菌组合物的有效成分。通式Ⅰ（I）的化合物可以通过酰化9,10-菲 - 二酮-9-肟或其碱金属或碱土金属盐来制备。

9. 发明授权

US4569914A Process for the sterile micropropagation of plant material 失效
标题翻译：植物材料的无菌微繁殖方法
公开(公告)号：US4569914A
公开(公告)日：1986-02-11
申请号：US508613
申请日：1983-06-28
申请人： Gyorgy Molnar , Peter Tetenyi , Eva Dobos , Jeno Bernath
发明人： Gyorgy Molnar , Peter Tetenyi , Eva Dobos , Jeno Bernath
IPC分类号： A01H3/00 , A01H4/00 , C12N5/00
CPC分类号： A01H4/005 , Y10S47/03
摘要： The invention relates to a process for the production of propagating material of plants by micropropagation in sterile tissue culture which comprises(a) planting sterile shoot cuttings of plants in solid nutrient medium in a suitable flask, filling up the flask with a suitable liquid nutrient medium optionally containing a growth regulator and growing the shoots in the submersed system; thereafter(b) cutting up into pieces the ramified culture thus obtained which contains a number of lateral buds and shoots, rooting the top-end shoots and planting the same after adaptation, and subjecting the cuttings prepared from the lower and middle parts of the shoot cultures to further cultivations according to step (a);and repeating steps (a) and (b) until the desired number of top-end shoots is reached.
摘要翻译：本发明涉及通过在无菌组织培养物中的微繁殖来生产植物繁殖材料的方法，其包括（a）在合适的烧瓶中将固体营养培养基中的植物的无菌枝条种植，用合适的液体营养培养基填充烧瓶任选地含有生长调节剂并在浸没体系中生长芽; 此后（b）将如此获得的分枝培养物切成片，其中包含许多侧芽和芽，在适应后生根顶端芽并种植它们，并对从枝条的下部和中部制备的切片文化进一步根据步骤（a）进行培养; 并重复步骤（a）和（b），直到达到所需数量的顶端射击。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式