专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2007195995A System, apparatus and method for chemical fixation of stentless cardiac valvular bioprostheses 审中-公开
标题翻译：系统，装置和方法，用于化学固定无牙周期性心脏生物多样性
公开(公告)号：JP2007195995A
公开(公告)日：2007-08-09
申请号：JP2007057893
申请日：2007-03-07
申请人： Edwards Lifesciences Corp , エドワーズライフサイエンシーズコーポレイションEdwards Lifesciences Corporation
发明人： QUINTERO LILLIAN , NGUYEN-THIEN-NHON DIANA
IPC分类号： A61F2/06 , A61F2/24 , A61L27/00
CPC分类号： A61F2/2415 , Y10S623/901
摘要： PROBLEM TO BE SOLVED: To prevent deformation or collapse of these sinuses during the tanning process of stentless aortic bioprosthesis. SOLUTION: The method is for fixing main aortic bioprosthesis of a collected donor animal including a main aortic segment of a mammal. It includes a process to provide a valve insert, which is provided with a substantially rigid tubular main body, a process of disposing the main aortic bioprosthesis on the insert, a process of supoprting right and left coronary aortic segments from the inside by means of a coronary support in such a way that the coronary support is extended outward to be removably fixed to the main body, a process of exposing the bio-protease to fixing agent as it is disposed on the insert, so that the bio-protease is fixed, and a process of removing the bio-protease from the valve insert. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了防止在无支架主动脉生物假体的鞣制过程中这些鼻窦的变形或塌陷。解决方案：该方法用于固定收集的供体动物的主要主动脉生物假体，包括哺乳动物的主要主动脉段。它包括一个提供一个阀芯插入件的过程，其中设有一个基本上刚性的管状主体，一个将主动脉主动脉生物假体放置在插入件上的过程，一个通过一个冠状支架以使得冠状支撑体向外延伸以可移除地固定到主体的方式，将生物蛋白酶暴露于固定剂并将其设置在插入物上的过程，使得生物蛋白酶被固定，以及从阀插入物去除生物蛋白酶的过程。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2005230580A Stentless bioprosthetic heart valve with coronary protuberances 审中-公开
标题翻译：具有冠状动脉粥样硬化的无菌生物心脏瓣膜
公开(公告)号：JP2005230580A
公开(公告)日：2005-09-02
申请号：JP2005147913
申请日：2005-05-20
申请人： Edwards Lifesciences Corp , エドワーズライフサイエンシーズコーポレイションEdwards Lifesciences Corporation
发明人： NGUYEN-THIEN-NHON DIANA
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2250/0097
摘要： PROBLEM TO BE SOLVED: To provide a new stentless bioprosthesis which includes non-ligated coronary artery segments fixed in an unligated, natural configuration, such that patient's endogenous coronary arteries may be anastomosed directly thereto. SOLUTION: This is a tanned stentless bioprosthetic heart valve: collected from an animal of mammal donor and tanned organization which includes an aorta having a wall, an inlet end, an outlet end, a lumen extended therethrough, and right and left coronary segments outward extended from the aorta segment which coronary segments have opening coronary lumens fixed by an almost natural anatomical structure and extended in the longitudinal direction therethrough, as a result, is equipped with an organ in which some blood flowing into the aorta segment can flow outward through the coronary lumen: and a plurality of valve leaflets placed in the aorta segment. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种新的无支架生物假体，其包括固定为未经配置的自然构型的非结扎冠状动脉段，使得患者的内源性冠状动脉可以直接与其吻合。
解决方案：这是一种鞣制的无支架生物假体心脏瓣膜：从哺乳动物供体和鞣制组织的动物收集，其包括具有壁，入口端，出口端，延伸穿过其的内腔和左冠状动脉和左冠状动脉的主动脉从主动脉段向外延伸的部分，冠状动脉段具有通过几乎天然的解剖结构固定的开放性冠状动脉腔，并且在纵向方向上延伸，结果，配备有流入主动脉段的一些血液可以向外流动的器官通过冠状动脉腔和多个放置在主动脉段中的瓣叶。版权所有（C）2005，JPO＆NCIPI

3. 发明专利

JP2009018180A Flexible heart valve 有权
标题翻译：灵活的心脏瓣膜
公开(公告)号：JP2009018180A
公开(公告)日：2009-01-29
申请号：JP2008218853
申请日：2008-08-27
申请人： Edwards Lifesciences Corp , エドワーズライフサイエンシーズコーポレイションEdwards Lifesciences Corporation
发明人： CARPENTIER ALAIN F , SCHRECK STEFAN G , RHEE RICHARD S , NGUYEN-THIEN-NHON DIANA , LAM HUNG LY , RECKTENWALD WILLIAM
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/005 , A61F2220/0066 , A61F2230/0013 , A61F2230/0023 , Y10S623/904
摘要： PROBLEM TO BE SOLVED: To provide a more flexible heart valve that responds to the natural motions of the annulus and downstream vessel walls. SOLUTION: A highly flexible tissue-type heart valve is disclosed having a structural stent in a generally cylindrical configuration with cusps 60 and commissures 62 that are permitted to move radially. The stent commissures are constructed so that the cusps 60 are pivotably or flexibly coupled together at the commissures 62 to permit relative movement therebetween. A connecting band 48 may be provided that follows the cusps 60 and commissures 62 and extends outwardly. A multi-legged holder is used to implant the valve, with the legs serving to maintain an implant shape to the valve. A method of implantation of the flexible valve using the holder is also disclosed. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种更灵活的心脏瓣膜，以响应环形和下游血管壁的自然运动。解决方案：公开了一种高度灵活的组织型心脏瓣膜，其具有大致圆柱形构造的结构支架，其中尖头60和合缝62允许径向移动。支架接合构造成使得尖端60在连接62处可枢转地或柔性地联接在一起以允许它们之间的相对运动。可以提供连接带48，其沿着尖头60和连合62并向外延伸。多腿支架用于植入瓣膜，腿部用于保持植入物的形状。还公开了使用保持器植入柔性阀的方法。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2010279730A Flexible heart valve 审中-公开
标题翻译：灵活的心脏瓣膜
公开(公告)号：JP2010279730A
公开(公告)日：2010-12-16
申请号：JP2010181984
申请日：2010-08-16
申请人： Edwards Lifesciences Corp , エドワーズライフサイエンシーズコーポレイションEdwards Lifesciences Corporation
发明人： CARPENTIER ALAIN F , FRATER ROBERT , LAM HUNG LY , NGUYEN-THIEN-NHON DIANA , RECKTENWALD WILLIAM J , RHEE RICHARD S , SCHRECK STEFAN G
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/005 , A61F2220/0066 , A61F2230/0013 , A61F2230/0023 , Y10S623/904
摘要： PROBLEM TO BE SOLVED: To provide a more flexible heart valve which is respondent to the natural motions of the annulus and downstream vessel walls. SOLUTION: Disclose is the highly flexible tissue-type heart valve having a structural stent 46 in a generally cylindrical configuration with cusps and commissures that are permitted to move radially. The stent commissures 62 are constructed so that the cusps are pivotably or flexibly coupled together at the commissures to permit relative movement therebetween. A connecting band may be provided that follows the cusps and commissures and extends outwardly. A multi-legged holder is used to implant the valve, with the legs serving to maintain an implant shape to the valve. A method of implantation of the flexible valve using the holder is also disclosed. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种更灵活的心脏瓣膜，其适用于环形和下游血管壁的自然运动。解决方案：Disclose是高度灵活的组织型心脏瓣膜，其具有大致圆柱形构造的结构支架46，其具有允许径向移动的尖和合并。支架接合部62被构造成使得尖端在连合处可枢转地或柔性地联接在一起以允许它们之间的相对运动。可以提供连接带，其沿着尖端和连接并且向外延伸。多腿支架用于植入瓣膜，腿部用于保持植入物的形状。还公开了使用保持器植入柔性阀的方法。版权所有（C）2011，JPO＆INPIT

5. 发明申请

WO0249545A2 HEART VALVE HOLDER THAT RESISTS SUTURE LOOPING 审中-公开
标题翻译：心脏保持器，能抵抗环绕
公开(公告)号：WO0249545A2
公开(公告)日：2002-06-27
申请号：PCT/US0149025
申请日：2001-12-13
申请人： EDWARDS LIFESCIENCES CORP
发明人： NGUYEN-THIEN-NHON DIANA , HOWANEC MYRON JR , KAFESJIAN RALPH , COSGROVE DELOS M , STOBIE ROBERT , LAM HUNG LY
IPC分类号： A61F2/24 , A61F2/48
CPC分类号： A61F2/2427 , A61F2/2412
摘要： An improved holder, system and method for implanting a tissue-type prosthetic mitral heart valve that prevents suture looping and may also constrict the commissure posts of the valve. The holder may include two relatively movable plates, one of which attaches to the valve sewing on the inflow end of the valve ring and the other which attaches via sutures or similar expedient to the valve commissures on the outflow end. Separation of the plates places the sutures in tension and constricts the commissures. The sutures may be strands or filaments, or may be wider bands of flexible biocompatible material. If bands are used, they desirably cover the commissure post tips to further help prevent suture looping thereover. The flexible lengths of material extend directly between commissures of the valve, or may extending radially inward from each commissure to a central upstanding member. Desirably, a slide is created by the flexible lengths of material adjacent each commissure post, for example by crossing over suture filaments at or radially inward from the commissure posts. If an upstanding member is used, the lengths of suture extend axially beyond the commissure post tips to create a tent that wards off sutures that otherwise might loop around the tips during advancement of the valve along an array of pre-implanted sutures.
摘要翻译：改进的用于植入组织型假体二尖瓣心脏瓣膜的保持器，系统和方法，其防止缝合线环绕并且还可以约束瓣膜的连合柱。保持器可以包括两个相对可移动的板，其中一个连接到阀环的流入端上的阀缝合，另一个通过缝合线或类似的方式附接到流出端上的阀连接。板的分离使缝合线处于紧张状态并限制合缝。缝合线可以是股线或长丝，或者可以是更宽的柔性生物相容性材料带。如果使用条带，它们理想地覆盖连合后端，以进一步有助于防止缝合在其上。柔性长度的材料在阀的连合之间直接延伸，或者可以从每个连接处径向向内延伸到中心直立构件。期望地，通过邻近每个连合柱的柔性长度的材料产生滑块，例如通过在接合柱上或径向向内穿过缝合线。如果使用直立的构件，则缝合线的长度轴向延伸超过连合后端，以产生防止缝合线的帐篷，否则，可以沿着预先植入的缝合线阵列推进阀门周围的尖端。

6. 发明申请

WO0042950A3 FLEXIBLE HEART VALVE 审中-公开
标题翻译：灵活的心脏瓣膜
公开(公告)号：WO0042950A3
公开(公告)日：2000-11-30
申请号：PCT/US0001855
申请日：2000-01-26
申请人： EDWARDS LIFESCIENCES CORP
发明人： CARPENTIER ALAIN F , SCHRECK STEFAN G , RHEE RICHARD S , NGUYEN-THIEN-NHON DIANA , LAM HUNG LY , RECKTENWALD WILLIAM
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/005 , A61F2220/0066 , A61F2230/0013 , A61F2230/0023 , Y10S623/904
摘要： A highly flexible tissue-type heart valve is disclosed having a structural stent in a generally cylindrical configuration with cusps and commissures that are permitted to move radially. The stent commissures are constructed so that the cusps are pivotably or flexibly coupled together at the commissures to permit relative movement therebetween. The stent may be cloth-covered and may be a single element or may be made in three separate elements for a three cusp valve, each element having a cusp portion and two commissure portions; adjacent commissure portions for each pair of adjacent stent element combining to form the stent commissures. If the stent has separate elements their commissure portions may be pivotably or flexibly coupled, or may be designed to completely separate into independent leaflets at bioresorbable couples. The cloth covering may have an outwardly projecting flap that mates with valve leaflets (e.g., pericardial leaflets) along the cusps and commissures. A connecting band may be provided that follows the cusps and commissures and extends outwardly. The valve is connected to the natural tissue along the undulating connecting band using conventional techniques, such as sutures. The connecting band may be a cloth-covered silicon member and attaches to the underside of the valve at the cusps to provide support to the stent and to the outer side of the valve at the commissures. A multi-legged holder is used to implant the valve, with the legs serving to maintain an implant shape to the valve. The holder may have six legs with one releasably connected to each cusp and one releasably connected to each commissure. A method of implantation of the flexible valve using the holder is also disclosed.
摘要翻译：公开了一种高度灵活的组织型心脏瓣膜，其具有大致圆柱形构造的结构支架，其具有允许径向移动的尖端和连合。支架接合构造成使得尖端在连合处可枢转地或柔性地联接在一起以允许它们之间的相对运动。支架可以是布覆盖的，并且可以是单个元件，或者可以用于三个阀瓣的三个单独的元件，每个元件具有尖部和两个连合部分; 每对相邻支架元件的相邻连合部分组合以形成支架连合。如果支架具有单独的元件，则其连合部分可以可枢转地或柔性地联接，或者可以被设计成在生物可再吸收的对处完全分离成独立的叶片。布覆盖物可以具有向外突出的翼片，其与沿着尖端和连合处的瓣叶（例如心包传单）配合。可以提供连接带，其沿着尖端和连接并且向外延伸。使用诸如缝合线的常规技术，瓣膜沿起伏的连接带连接到天然组织。连接带可以是布覆盖的硅构件，并且在尖端处附接到阀的下侧，以在连合处向支架和阀的外侧提供支撑。多腿支架用于植入瓣膜，腿部用于保持植入物的形状。保持器可以具有六个腿，一个可释放地连接到每个尖端，并且一个可释放地连接到每个连合部。还公开了使用保持器植入柔性阀的方法。

7. 发明公开

EP3322383A4 PROSTHETIC HEART VALVE 有权
公开(公告)号：EP3322383A4
公开(公告)日：2018-07-25
申请号：EP16825207
申请日：2016-07-14
申请人： EDWARDS LIFESCIENCES CORP
发明人： NGUYEN-THIEN-NHON DIANA , GEISER TIMOTHY A , WOOD LARRY L , SIRIMANNE DINESH L , NGUYEN SON V , LEVI TAMIR S , GUROVICH NIKOLAY , BUKIN MICHAEL
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2002/072 , A61F2210/0076 , A61F2220/0075 , A61F2230/0026 , A61F2230/0093 , A61F2250/0003 , A61F2250/0039 , A61F2250/0069
摘要： An implantable prosthetic valve can comprise an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration, the frame defining an axial direction extending from the inflow end to the outflow end, a leaflet structure positioned within the frame and secured thereto, and an annular outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises an inflow edge secured to the frame at a first location, an outflow edge comprising a plurality of alternating projections and notches, wherein the projections are secured to the frame at a second location, and the notches are not directly secured to the frame, an intermediate portion between the inflow edge and the outflow edge that comprises a plurality of openings.

8. 发明专利

CL2019003438A1 Miembro de sellado protesis vasculares cardiacas. 未知
公开(公告)号：CL2019003438A1
公开(公告)日：2020-05-08
申请号：CL2019003438
申请日：2019-11-25
申请人： EDWARDS LIFESCIENCES CORP
发明人： HOANG LIEN HUONG THI , NGUYEN SON V , NGO HIEN TRAN , TRAN VIVIAN , JOSEPH RUSSELL T , SIRIMANNE DINESH L , RUPP KEVIN D , NGUYEN-THIEN-NHON DIANA
IPC分类号： A61F2/24
摘要： UNA VÁLVULA CARDÍACA PROTÉSICA INCLUYE UN BASTIDOR ANULAR QUE TIENE UN EXTREMO DE FLUJO DE ENTRADA Y UN EXTREMO DE FLUJO DE SALIDA Y QUE ES COMPRIMIBLE Y EXPANDIBLE RADIALMENTE ENTRE UNA CONFIGURACIÓN COMPRIMIDA RADIALMENTE Y UNA CONFIGURACIÓN EXPANDIDA RADIALMENTE. LA VÁLVULA CARDÍACA PROTÉSICA INCLUYE ADEMÁS UNA ESTRUCTURA DE HOJILLA COLOCADA DENTRO DEL BASTIDOR Y ASEGURADA AL MISMO, Y UN MIEMBRO SELLANTE EXTERIOR MONTADO EN EL EXTERIOR DEL BASTIDOR Y ADAPTADO PARA SELLAR CONTRA EL TEJIDO CIRCUNDANTE CUANDO LA VÁLVULA CARDÍACA PROTÉSICA ES IMPLANTADA DENTRO DE UN ANILLO DE VÁLVULA CARDÍACA NATIVA DE UN PACIENTE. EL MIEMBRO SELLANTE PUEDE INCLUIR UNA CAPA DE MALLA Y UNA CAPA DE PELOS QUE COMPRENDEN UNA PLURALIDAD DE HILOS DE PELOS QUE SE EXTIENDEN HACIA AFUERA DESDE LA CAPA DE MALLA.

9. 发明专利

CA2358521C FLEXIBLE HEART VALVE 未知
公开(公告)号：CA2358521C
公开(公告)日：2009-12-29
申请号：CA2358521
申请日：2000-01-26
申请人： EDWARDS LIFESCIENCES CORP
发明人： SCHRECK STEFAN G , CARPENTIER ALAIN F , RECKTENWALD WILLIAM , RHEE RICHARD S , LAM HUNG LY , NGUYEN-THIEN-NHON DIANA
IPC分类号： A61F2/24 , A61L27/38
摘要： A highly flexible tissue-type heart valve is disclosed having a structural stent in a generally cylindrical configuration with cusps and commissures that are permitted to move radially. The stent commissures are constructed so that the cusps are pivotably or flexibly coupled together at the commissures to permit relative movement therebetween. The stent may be cloth- covered and may be a single element or may be made in three separate elements for a three cusp valve, each element having a cusp portion and two commissure portions; adjacent commissure portions for each pair of adjacent stent element combining to form the stent commissures. If the stent has separate elements their commissure portions may be pivotably or flexibly coupled, or may be designed to completely separate into independent leaflets at bioresorbable couples. The cloth covering may have an outwardly projecting flap that mates with valve leaflets (e.g., peri- cardial leaflets) along the cusps and commissures. A connecting band may be provided that follows the cusps and commissures and extends outwardly. The valve is connected to the natural tissue along the undulating connecting band using conventional techniques, such as sutures. The connecting band may be a cloth-covered silicon member and attaches to the underside of the valve at the cusps to provide support to the stent and to the outer side of the valve at the commissures. A multi-legged holder is used to implant the valve, with the legs serving to maintain an implant shape to the valve. The holder may have six legs with one releasably connected to each cusp and one releasably connected to each commissure. A method of implantation of the flexible valve using the holder is also disclosed.

10. 发明专利

DE60037309T2 未知
公开(公告)号：DE60037309T2
公开(公告)日：2008-11-27
申请号：DE60037309
申请日：2000-01-26
申请人： EDWARDS LIFESCIENCES CORP
发明人： CARPENTIER ALAIN F , SCHRECK STEFAN G , RHEE RICHARD S , NGUYEN-THIEN-NHON DIANA , LAM HUNG LY , RECKTENWALD WILLIAM
IPC分类号： A61F2/24
摘要： A prosthetic heart valve (40) for implant at an aortic annulus, comprising: an elongate rod-like flexible stent (46, 250, 280, 290, 300, 310, 320) having alternating inflow cusps (60) and outflow commissures (62) made of an elastic material; a plurality of flexible leaflets (42) attached to the stent so as to form a one-way valve within the stent; and a suture-permeable connecting band (48) attached to the stent providing an interface between the valve and surrounding host tissue, wherein the connecting band shape mimics the alternating stent cusps and commissures and provides a flexible interface for suturing that conforms to a natural aortic root, and wherein the flexible stent is relatively more rigid than the leaflets and connecting band and acts to limit total flexibility of the valve, and wherein the stent is flexible to permit the cusps to move radially relative to each other about the commissures, and wherein the connecting band defines axial gaps (142) opening in the inflow direction between the cusps of the stent to minimize interference with pivoting movement of the stent cusps.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式