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1. 发明授权

US6051556A Hybrid pesticidal toxins 失效
标题翻译：杂种杀虫毒素
公开(公告)号：US6051556A
公开(公告)日：2000-04-18
申请号：US438465
申请日：1995-05-10
申请人： Edward R. Wilcox , David L. Edwards , George E. Schwab , Mark Thompson , Paul Culver
发明人： Edward R. Wilcox , David L. Edwards , George E. Schwab , Mark Thompson , Paul Culver
IPC分类号： C07K14/325 , C07K14/34 , C12N15/62 , A61K38/00 , C07K1/00
CPC分类号： C12N15/62 , C07K14/325 , C07K14/34 , C07K2319/00 , C07K2319/035 , C07K2319/55
摘要： The invention concerns novel hybrid pesticidal toxins. These toxins are expressed as the fusion protein of a chimeric gene. Specifically exemplified is a novel B.t. hybrid toxin. These novel toxins have increased toxicity against target pests. The invention also concerns a process for preparing a hybrid virus having an altered insect host range.
摘要翻译：本发明涉及新型杂种杀虫毒素。这些毒素被表达为嵌合基因的融合蛋白。具体例子是一个小说B.t. 杂交毒素。这些新型毒素对目标害虫的毒性增加。本发明还涉及制备具有改变的昆虫宿主范围的杂种病毒的方法。

2. 发明授权

US5290914A Hybrid diphtheria-B.t. pesticidal toxins 失效
标题翻译：混合白喉杀虫毒素
公开(公告)号：US5290914A
公开(公告)日：1994-03-01
申请号：US187167
申请日：1988-04-28
申请人： Edward Wilcox , David L. Edwards , George E. Schwab , Mark Thompson , Paul Culver
发明人： Edward Wilcox , David L. Edwards , George E. Schwab , Mark Thompson , Paul Culver
IPC分类号： C12N9/00 , A01N63/00 , C07K14/00 , C07K14/195 , C07K14/325 , C07K14/34 , C07K14/41 , C07K14/415 , C07K19/00 , C12N1/21 , C12N15/62 , C12P21/02 , C12R1/38 , C07K13/00 , C12N15/00 , C12P21/06
CPC分类号： C12N15/62 , C07K14/325 , C07K14/34 , C07K2319/035 , C07K2319/55
摘要： The invention concerns novel hybrid pesticidal toxins. These toxins are expressed as the fusion protein of a chimeric gene. Specifically exemplified is a novel B.t. hybrid toxin. These novel toxins have increased toxicity against target pests. The invention also concerns a process for preparing a hybrid virus having an altered insect host range.
摘要翻译：本发明涉及新型杂种杀虫毒素。这些毒素被表达为嵌合基因的融合蛋白。具体例子是一个小说B.t. 杂交毒素。这些新型毒素对目标害虫的毒性增加。本发明还涉及制备具有改变的昆虫宿主范围的杂种病毒的方法。

3. 发明授权

US5932209A Bacillus thuringiensis .delta.-endotoxin 失效
标题翻译：苏云金芽孢杆菌δ-内毒素
公开(公告)号：US5932209A
公开(公告)日：1999-08-03
申请号：US732495
申请日：1997-03-06
申请人： Mark Thompson , George E. Schwab , H. Ernest Schnepf , Brian Stockhoff
发明人： Mark Thompson , George E. Schwab , H. Ernest Schnepf , Brian Stockhoff
IPC分类号： A01M1/20 , A01N63/02 , C07K14/325 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/32 , C12P21/02 , C12R1/07 , C12R1/91 , A01N63/00 , A01N37/18
CPC分类号： C07K14/325 , C07K2319/00 , Y10S424/832 , Y10S530/825
摘要： An improved Bacillus thuringiensis (B.t.) delta-endotoxin is created by the modification of the gene encoding the toxin. The toxicity of a B.t. toxin was improved by replacing the native protoxin segment with an alternate protoxin segment by constructing a chimeric toxin gene.
摘要翻译： PCT No.PCT / US95 / 05090 Sec。 371日期1997年3月6日 102（e）日期1997年3月6日PCT提交1995年5月5日PCT公布。 WO95 / 30752 PCT出版物日期1995年11月16日改良的苏云金芽孢杆菌（B.t.）δ-内毒素是通过修饰编码毒素的基因产生的。 B.t.的毒性通过构建嵌合毒素基因，用替代的原毒素片段代替天然原毒素片段来改善毒素。

4. 发明授权

US5827514A Pesticidal compositions 失效
公开(公告)号：US5827514A
公开(公告)日：1998-10-27
申请号：US598305
申请日：1996-02-08
申请人： Gregory A. Bradfisch , Mark Thompson , George E. Schwab
发明人： Gregory A. Bradfisch , Mark Thompson , George E. Schwab
IPC分类号： C12N15/09 , A01N37/20 , A01N63/02 , C07K7/06 , C07K7/08 , C07K14/325 , C12N1/21 , C12N15/32 , C12P21/02 , C12R1/19 , C12R1/39 , A01N63/00 , C12N5/14
CPC分类号： C07K14/325 , A01N63/02 , C07K2319/00
摘要： Disclosed are compositions and processes for controlling lepidopteran pests. These compositions comprise synergistic combinations of a CryIF chimeric and CryIA(c) chimeric Bacillus thuringiensis .delta.-endotoxin. These compositions have been found to exhibit excellent activity against lepidopteran pests.

5. 发明授权

US5840554A .beta.-Endotoxin expression in pseudomonas fluorescens 失效
公开(公告)号：US5840554A
公开(公告)日：1998-11-24
申请号：US639923
申请日：1996-04-24
申请人： Mark Thompson , George E. Schwab
发明人： Mark Thompson , George E. Schwab
IPC分类号： C12N15/09 , A01N63/00 , C07K14/325 , C12N1/21 , C12N5/10 , C12N15/00 , C12N15/32 , C12P21/02 , C12R1/07 , C12R1/39 , C12N15/11 , C12N15/78
CPC分类号： A01N63/00 , C07K14/325 , C07K2317/24 , C07K2319/00
摘要： Bacillus thuringiensis endotoxin expression in Pseudomonads can be improved by modifying the gene encoding the Bacillus thuringiensis endotoxin. Chimeric genes are created by replacing the segment of the Bacillus thuringiensis gene encoding a native protoxin with a segment encoding a different protoxin. Exemplified herein is the cryIF/cryI(b) chimera wherein the native cryIF protoxin segment has been substituted by the cryIA(b) protoxin segment, to yield improved expression of the cryIF toxin in Pseudomonads. The invention also concerns novel genes and plasmids.

6. 发明授权

US5527883A Delta-endotoxin expression in pseudomonas fluorescens 失效
标题翻译：假单胞菌荧光素中的δ-内毒素表达
公开(公告)号：US5527883A
公开(公告)日：1996-06-18
申请号：US239476
申请日：1994-05-06
申请人： Mark Thompson , George E. Schwab
发明人： Mark Thompson , George E. Schwab
IPC分类号： C12N15/09 , A01N63/00 , C07K14/325 , C12N1/21 , C12N5/10 , C12N15/00 , C12N15/32 , C12P21/02 , C12R1/07 , C12R1/39 , C12N15/62 , C12N15/78
CPC分类号： A01N63/00 , C07K14/325 , C07K2317/24 , C07K2319/00
摘要： Bacillus thuringiensis endotoxin expression in Pseudomonads can be improved by modifying the gene encoding the Bacillus thuringiensis endotoxin. Chimeric genes are created by replacing the segment of the Bacillus thuringiensis gene encoding a native protoxin with a segment encoding a different protoxin. Exemplified herein is the cryIF/cryI(b) chimera wherein the native cryIF protoxin segment has been substituted by the cryIA(b) protoxin segment, to yield improved expression of the cryIF toxin in Pseudomonads. The invention also concerns novel genes and plasmids.
摘要翻译：通过修饰编码苏云金芽孢杆菌内毒素的基因可以改善拟南芥中苏云金芽孢杆菌内毒素的表达。通过用编码不同原毒素的片段替代编码天然原毒素的苏云金芽孢杆菌基因片段来产生嵌合基因。本文例示的是cryIF / cryI（b）嵌合体，其中天然cryIF原毒素区段已被cryIA（b）原毒素区段取代，以产生在假单胞菌中cryIF毒素的改进的表达。本发明还涉及新基因和质粒。

7. 发明授权

US5593881A Bacillus thuringiensis delta-endotoxin 失效
标题翻译：苏云金芽孢杆菌δ-内毒素
公开(公告)号：US5593881A
公开(公告)日：1997-01-14
申请号：US239474
申请日：1994-05-06
申请人： Mark Thompson , George E. Schwab , H. Ernest Schnepf , Brian Stockhoff
发明人： Mark Thompson , George E. Schwab , H. Ernest Schnepf , Brian Stockhoff
IPC分类号： A01M1/20 , A01N63/02 , C07K14/325 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/32 , C12P21/02 , C12R1/07 , C12R1/91 , C07H21/04 , C12N15/63
CPC分类号： C07K14/325 , C07K2319/00 , Y10S424/832 , Y10S530/825
摘要： An improved Bacillus thuringiensis (B.t.) delta-endotoxin is created by the modification of the gene encoding the toxin. The toxicity of a B.t. toxin was improved by replacing the native protoxin segment with an alternate protoxin segment by constructing a chimeric toxin gene.
摘要翻译：通过修饰编码毒素的基因产生改良的苏云金芽孢杆菌（B.t.）δ-内毒素。 B.t.的毒性通过构建嵌合毒素基因，用替代的原毒素片段代替天然原毒素片段来改善毒素。

8. 发明授权

US5508264A Pesticidal compositions 失效
标题翻译：杀虫剂组合物
公开(公告)号：US5508264A
公开(公告)日：1996-04-16
申请号：US349867
申请日：1994-12-06
申请人： Gregory A. Bradfisch , Mark Thompson , George E. Schwab
发明人： Gregory A. Bradfisch , Mark Thompson , George E. Schwab
IPC分类号： C12N15/09 , A01N37/20 , A01N63/02 , C07K7/06 , C07K7/08 , C07K14/325 , C12N1/21 , C12N15/32 , C12P21/02 , C12R1/19 , C12R1/39 , A61K38/16
CPC分类号： C07K14/325 , A01N63/02 , C07K2319/00
摘要： Disclosed are compositions and processes for controlling lepidopteran pests. These compositions comprise synergistic combinations of a CryIF chimeric and CryIA(c) chimeric Bacillus thuringiensis .delta.-endotoxin. These compositions have been found to exhibit excellent activity against lepidopteran pests.
摘要翻译：披露了控制鳞翅目害虫的组合物和方法。这些组合物包含CryIF嵌合和CryIA（c）嵌合苏云金芽孢杆菌δ-内毒素的协同组合。已经发现这些组合物对鳞翅目害虫表现出优异的活性。

9. 发明授权

US5430137A Probes for the identification of Bacillus thuringiensis endotoxin genes 失效
标题翻译：用于鉴定苏云金芽孢杆菌内毒素基因的探针
公开(公告)号：US5430137A
公开(公告)日：1995-07-04
申请号：US968781
申请日：1992-10-30
申请人： Frank H. Gaertner , August J. Sick , Mark Thompson , H. Ernest Schnepf , George E. Schwab , Kenneth E. Narva
发明人： Frank H. Gaertner , August J. Sick , Mark Thompson , H. Ernest Schnepf , George E. Schwab , Kenneth E. Narva
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/689
摘要： This invention concerns novel gene probes which can be used to identify DNA from Bacillus thuringiensis microbes which encode protein endotoxins. The invention probes greatly facilitate the search for useful microbes hosting genes which encode toxins.
摘要翻译：本发明涉及可用于鉴定编码蛋白质内毒素的苏云金芽孢杆菌微生物DNA的新型基因探针。本发明探针极大地促进了寻找编码毒素的基因的有用微生物。

10. 发明授权

US11285502B2 Cleaning device 有权
公开(公告)号：US11285502B2
公开(公告)日：2022-03-29
申请号：US16879699
申请日：2020-05-20
申请人： Mark Thompson
发明人： Mark Thompson
IPC分类号： B05B11/00 , B08B3/04
摘要： A cleaning device includes a cartridge assembly, a hose/tubing, a nozzle, and an activator. The cartridge assembly includes at least one cartridge configured to hold a liquid solution. An attachment device is coupled to the cartridge assembly and is configured to secure the position of the cartridge assembly to a user's arm adjacent the hand. A pump is located within the cleaning device and is located between cartridge and the nozzle, such that pump regulates dispensing of the liquid solution. The nozzle is in communication with the pump and acts as a diffuser to adjust the stream of the liquid solution passed through the hose from pump. The activator is in communication with the pump such that operation of the activator selectively releases a volume of the liquid solution from the cartridge so as to pass through the nozzle. A control unit and interface are permitted.

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