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1. 发明申请

US20110014290A1 SYSTEM AND METHOD FOR FACILITATING HEMOSTASIS WITH AN ABSORBABLE SPONGE 审中-公开
标题翻译：用可吸收海绵促进HEMOSTASIS的系统和方法
公开(公告)号：US20110014290A1
公开(公告)日：2011-01-20
申请号：US12887945
申请日：2010-09-22
申请人： Eduardo Chi Sing , Mark Ashby , Tin Tran , Richard Greff
发明人： Eduardo Chi Sing , Mark Ashby , Tin Tran , Richard Greff
IPC分类号： A61K38/48 , A61K38/16 , A61K9/10 , A61P7/04
CPC分类号： A61K9/122 , A61K9/0014 , A61K38/39 , A61K38/4833 , A61K2300/00
摘要： The present invention provides for a method and apparatus to provide hemostasis at a blood vessel puncture site, having a hemostasis material and a clot formation accelerator, wherein said clot formation accelerator is substantially dispersed throughout said hemostasis material.
摘要翻译：本发明提供了一种在血管穿刺部位提供止血的方法和装置，其具有止血材料和凝块形成促进剂，其中所述凝块形成促进剂基本上分散在所述止血材料中。

2. 发明申请

US20100036414A1 SYSTEM AND METHOD FOR FACILITATING HEMOSTASIS OF BLOOD VESSEL PUNCTURES WITH ABSORBABLE SPONGE 审中-公开
标题翻译：用可吸收海绵促进血管瘤的血管造影的系统和方法
公开(公告)号：US20100036414A1
公开(公告)日：2010-02-11
申请号：US12571929
申请日：2009-10-01
申请人： Andrew M. Cragg , Rodney Brenneman , Mark Ashby , Eduardo Chi Sing
发明人： Andrew M. Cragg , Rodney Brenneman , Mark Ashby , Eduardo Chi Sing
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00362 , A61B2017/00407 , A61B2017/00637 , A61B2017/00654 , A61B2017/00898 , A61F13/26 , A61F2013/00463
摘要： A system for facilitating hemostasis of a puncture site in a blood vessel injects an absorbable sponge pledget in a hydrated state to a position at an exterior of the blood vessel puncture to facilitate hemostasis. The system includes a tract dilator for locating the puncture, an introducer, and a pusher. The introducer includes a staging chamber for receiving the absorbent sponge pledget and a delivery chamber having a diameter smaller than a diameter of the staging chamber into which a hydrated pledget passes. The pledget is hydrated and compressed within the introducer and then ejected with the pusher to the delivery site to facilitate hemostasis of the blood vessel puncture. The system delivers the absorbable sponge pledget over a guidewire to ensure the proper positioning of the pledget over the puncture. The implanted absorbable sponge once delivered expands rapidly to fill the target site and is absorbed by the body over time.
摘要翻译：用于促进血管中穿刺部位止血的系统将水合状态的可吸收海绵状物质注入到血管穿刺外部的位置，以促进止血。该系统包括用于定位穿刺的管道扩张器，导引器和推动器。引导器包括用于接收吸收性海绵质量分数的分级室和具有比水合物渗透到的分级室直径小的直径的输送室。在导引器内水合并压缩毛细管，然后将推送器与推送器一起喷射到输送部位，以促进血管穿刺止血。系统通过导丝将可吸收的海绵填充物传送到导线上，以确保穿刺物在穿刺上的正确定位。植入的可吸收海绵一旦交付迅速扩张，填补目标部位，随着时间的推移被身体吸收。

3. 发明授权

US06183497B2 Absorbable sponge with contrasting agent 有权
标题翻译：可吸收海绵与对比剂
公开(公告)号：US06183497B2
公开(公告)日：2001-02-06
申请号：US09335452
申请日：1999-06-17
申请人： Eduardo Chi Sing , Mark Ashby
发明人： Eduardo Chi Sing , Mark Ashby
IPC分类号： A61B1708
CPC分类号： A61M31/005 , A61B6/03 , A61B6/481 , A61B6/485 , A61B8/481 , A61B10/0233 , A61B17/0057 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2090/3933
摘要： An absorbable sponge containing a contrasting agent (e.g, radiopaque agent) that can be introduced to a biopsy tract or other puncture wound site is provided. The contrasting agent permits identification of the site by fluoroscopy or other imaging techniques.
摘要翻译：提供了一种可吸收的海绵，其中含有可引入到活检管道或其他穿刺伤口部位的造影剂（例如不透射线剂）。对比剂允许通过荧光透视或其他成像技术鉴定位点。

4. 发明授权

US07955353B1 Dissolvable closure device 有权
标题翻译：可溶性闭合装置
公开(公告)号：US07955353B1
公开(公告)日：2011-06-07
申请号：US10461587
申请日：2003-06-12
申请人： Mark Ashby , Eduardo Chi Sing , Tin T. Tran
发明人： Mark Ashby , Eduardo Chi Sing , Tin T. Tran
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898 , A61B2017/0406 , A61B2017/3419 , A61B2017/3482 , A61L31/045 , A61L31/146 , A61L31/148 , A61L2400/04
摘要： The present invention provides for a method and apparatus to provide hemostasis at a puncture site having a communication tube with a lumen, a top and a bottom; a hemostatic material positioned around the communication tube bottom, the hemostatic material having a first end and a second end; and a hemostatic material cover positioned around the hemostatic material and the communication tube bottom, wherein the hemostatic material cover forms a hollow distal tip cavity at the hemostatic material first end.
摘要翻译：本发明提供一种在具有内腔，顶部和底部的连通管的穿刺部位提供止血的方法和装置，止血材料定位在连通管底部周围，止血材料具有第一端和第二端; 以及围绕止血材料和连通管底部定位的止血材料罩，其中所述止血材料罩在所述止血材料第一端处形成中空的远端末端腔。

5. 发明申请

US20100029908A1 ABSORBABLE SPONGE WITH CONTRASTING AGENT 审中-公开
标题翻译：可吸收海绵与对比剂
公开(公告)号：US20100029908A1
公开(公告)日：2010-02-04
申请号：US12578088
申请日：2009-10-13
申请人： Eduardo Chi Sing , Mark Ashby
发明人： Eduardo Chi Sing , Mark Ashby
IPC分类号： C07K14/00
CPC分类号： A61M31/005 , A61B6/03 , A61B6/481 , A61B6/485 , A61B8/481 , A61B10/0233 , A61B17/0057 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2090/3933
摘要： An absorbable sponge containing a contrasting agent (e.g., radiopaque agent) that can be introduced to a biopsy tract or other puncture wound site is provided. The contrasting agent permits identification of the site by fluoroscopy or other imaging techniques.
摘要翻译：提供了一种可吸收海绵，其含有能够引入到活检管道或其它穿刺伤口部位的造影剂（例如不透射线剂）。对比剂允许通过荧光透视或其他成像技术鉴定位点。

6. 发明授权

US07618567B2 Absorbable sponge with contrasting agent 失效
公开(公告)号：US07618567B2
公开(公告)日：2009-11-17
申请号：US10978321
申请日：2004-10-29
申请人： Eduardo Chi Sing , Mark Ashby
发明人： Eduardo Chi Sing , Mark Ashby
IPC分类号： A61B17/08
CPC分类号： A61M31/005 , A61B6/03 , A61B6/481 , A61B6/485 , A61B8/481 , A61B10/0233 , A61B17/0057 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2090/3933
摘要： An absorbable sponge containing a contrasting agent (e.g, radiopaque agent) that can be introduced to a biopsy tract or other puncture wound site is provided. The contrasting agent permits identification of the site by fluoroscopy or other imaging techniques.

7. 发明授权

US07029489B1 System and method for delivering hemostasis promoting material to a blood vessel puncture site 有权
标题翻译：将止血促进材料输送到血管穿刺部位的系统和方法
公开(公告)号：US07029489B1
公开(公告)日：2006-04-18
申请号：US10461035
申请日：2003-06-13
申请人： Mark Ashby , Luis R. Urquidi , Eduardo Chi Sing
发明人： Mark Ashby , Luis R. Urquidi , Eduardo Chi Sing
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672
摘要： A system for delivering hemostasis promoting material of the present invention allows the hemostasis promoting material to be delivered to a blood vessel puncture site by fluid pressure. The system allows the hemostasis promoting material to be delivered through an introducer sheath which is already in place within a tissue tract. This system includes a controlled tip which is insertable through the introducer sheath to locate and occlude the blood vessel puncture site and a hydration chamber for receiving and delivering the hemostasis promoting material to the blood vessel puncture site. The system accurately locates the blood vessel wall at a puncture site and for properly placing a hemostasis plug over the puncture site.
摘要翻译：用于输送本发明止血促进材料的系统允许止血促进材料通过流体压力输送到血管穿刺部位。该系统允许止血促进材料通过已经在组织管内已经就位的导引器鞘被递送。该系统包括可控制的尖端，其可插入穿过引导器护套以定位和闭塞血管穿刺部位，以及用于接收和输送止血促进材料到血管穿刺部位的水合室。系统准确地将穿刺部位的血管壁定位，并将止血塞适当地放置在穿刺部位上。

8. 发明授权

US08317821B1 Release mechanism 有权
标题翻译：释放机制
公开(公告)号：US08317821B1
公开(公告)日：2012-11-27
申请号：US10462064
申请日：2003-06-12
申请人： Mark Ashby , Eduardo Chi Sing , Luis R. Urquidi , Tin Tran
发明人： Mark Ashby , Eduardo Chi Sing , Luis R. Urquidi , Tin Tran
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898 , A61B2017/3419 , A61B2017/3482
摘要： The present invention provides for a method and apparatus related to a releasable mechanism having a first connector having a first end and a second end, a second connector having a top and a bottom, a first notch positioned near the first connector second end to releasably mate with the second connector bottom, and a second notch located near the second connector bottom to releasably receive the first connector second end.
摘要翻译：本发明提供了一种与可释放机构相关的方法和装置，其具有第一连接器，其具有第一端和第二端，具有顶部和底部的第二连接器，位于第一连接器第二端附近的第一切口以可释放地配合以及位于第二连接器底部附近的可释放地接收第一连接器第二端的第二凹口。

9. 发明授权

US08050741B2 Device and method for facilitating hemostasis of a biopsy tract 有权
标题翻译：促进活检道止血的装置和方法
公开(公告)号：US08050741B2
公开(公告)日：2011-11-01
申请号：US11019971
申请日：2004-12-21
申请人： Mark Ashby , Vaughn P. Whalen , Eduardo Chi Sing
发明人： Mark Ashby , Vaughn P. Whalen , Eduardo Chi Sing
IPC分类号： A61B6/00 , A61B10/00
CPC分类号： A61B17/0057 , A61B10/02 , A61B10/0233 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654
摘要： A biopsy cannula and a delivery catheter are configured to deliver one or more absorbable sponge pledgets to a biopsy site after removal of one or more tissue samples from the site. The delivery catheter allows a large amount of hydrated sponge material to be delivery to the biopsy site to facilitate hemostasis. One example of the delivery catheter includes a closed distal end, a side port, a tapered section, and an enlarged proximal portion for receiving the pledget. The side port of the delivery catheter is arranged to delivery the pledget through the side port of the biopsy cannula. In order to fill a relatively large biopsy site where multiple tissue samples have been taken in a radial pattern, the biopsy cannula is rotated and additional pledgets are delivered to the biopsy site at different radial locations. The absorbable sponge pledget may also be used as a marker for location of the biopsy site at a later time.
摘要翻译：活检插管和递送导管构造成在从该部位移除一个或多个组织样本之后将一个或多个可吸收海绵质量递送到活检部位。输送导管允许大量水合海绵材料输送到活检部位以促进止血。输送导管的一个实例包括封闭的远端，侧端口，锥形部分和用于接收毛细管的扩大的近端部分。输送导管的侧端口布置成通过活检插管的侧端口递送毛细管。为了填充已经以径向图案拍摄多个组织样本的相对较大的活检部位，旋转活检插管，并且在不同的径向位置将额外的药物递送至活组织检查部位。吸收性海绵片也可以用作活检部位的位置的标记。

10. 发明授权

US07037322B1 System and method for delivering hemostasis promoting material to a blood vessel puncture with a staging tube 有权
标题翻译：用止血管将止血促进材料输送到血管穿刺的系统和方法
公开(公告)号：US07037322B1
公开(公告)日：2006-05-02
申请号：US10461006
申请日：2003-06-13
申请人： Eduardo Chi Sing , Mark Ashby , Luis R. Urquidi
发明人： Eduardo Chi Sing , Mark Ashby , Luis R. Urquidi
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00491 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2090/062
摘要： A system for delivering hemostasis promoting material of the present invention allows the hemostasis promoting material to be delivered to a blood vessel puncture site by fluid pressure. The system allows the hemostasis promoting material to be delivered through an introducer sheath which is already in place within a tissue tract. This system includes a controlled tip which is insertable through the introducer sheath to locate and occlude the blood vessel puncture site and a hydration chamber for receiving and delivering the hemostasis promoting material to the blood vessel puncture site. The system accurately locates the blood vessel wall at a puncture site and for properly placing a hemostasis plug over the puncture site.
摘要翻译：用于输送本发明止血促进材料的系统允许止血促进材料通过流体压力输送到血管穿刺部位。该系统允许止血促进材料通过已经在组织管内已经就位的导引器鞘被递送。该系统包括可控制的尖端，其可插入穿过引导器护套以定位和闭塞血管穿刺部位，以及用于接收和输送止血促进材料到血管穿刺部位的水合室。系统准确地将穿刺部位的血管壁定位，并将止血塞适当地放置在穿刺部位上。

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