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1. 发明授权

US4771003A Heat stable alkaline proteases produced by a bacillus 失效
标题翻译：由杆菌产生的热稳定性碱性蛋白酶
公开(公告)号：US4771003A
公开(公告)日：1988-09-13
申请号：US790256
申请日：1985-10-22
申请人： Edmund J. Stellwag , Donald R. Durham , Wayne E. Swann , Carol A. Nolf , David B. Stewart
发明人： Edmund J. Stellwag , Donald R. Durham , Wayne E. Swann , Carol A. Nolf , David B. Stewart
IPC分类号： C12N1/20 , C11D3/386 , C12N9/54 , C12R1/07
CPC分类号： C12R1/07 , C11D3/386 , C12N9/54 , Y10S435/832
摘要： Novel enzymes exhibiting proteolytic activity in alkaline media and stability at high temperatures and under alkaline conditions are produced by a novel Bacillus strain designated GX6638 or its mutants or variants. These enzymes are especially well-suited for inclusion in washing compositions. A culture of GX6638 has been deposited with the American Type Culture Collection, Rockville, Md. as ATCC No. 53278.
摘要翻译：在碱性介质中表现出蛋白水解活性的新型酶和在高温和碱性条件下的稳定性通过命名为GX6638或其突变体或变体的新型芽孢杆菌菌株产生。这些酶特别适合包含在洗涤组合物中。 GX6638的文化已经保藏在美国典型培养物保藏中心，Rockville，Md。，ATCC No.53278。

2. 发明授权

US4749653A Enzyme immobilization on non-porous glass fibers 失效
标题翻译：酶固定在无孔玻璃纤维上
公开(公告)号：US4749653A
公开(公告)日：1988-06-07
申请号：US789530
申请日：1985-10-21
申请人： David M. Lee , Gary M. Nishioka , Wayne E. Swann , Carol A. Nolf
发明人： David M. Lee , Gary M. Nishioka , Wayne E. Swann , Carol A. Nolf
IPC分类号： C12N11/14 , C12N11/02 , C12N11/08
CPC分类号： C12N11/14
摘要： Enzymes are immobilized on non-porous glass fibers by coating glass fibers with a solution containing an enzyme and a soluble polymer and contacting the coated fibers with a controlled amount of cross-linking agent to obtain an immobilized enzyme having high activity and long endurance, and which provides a high percentage of conversion. The enzyme may be an amylase, the polymer a plyalkyleneimine and the cross-linking agent glutaraldehyde. Continuous immobilization can be carried out by moving continuous fibers to applicator stations for applying a solution of enzyme and polymer and a solution of cross-linking agent.
摘要翻译：通过用含有酶和可溶性聚合物的溶液涂覆玻璃纤维并将涂覆的纤维与受控量的交联剂接触以将酶固定在无孔玻璃纤维上，以获得具有高活性和长耐久性的固定化酶，以及这提供了很高的转化率。酶可以是淀粉酶，聚合物是烯丙基亚胺和交联剂戊二醛。连续固定可以通过将连续纤维移动到施用站来施加酶和聚合物溶液和交联剂溶液来进行。

3. 发明授权

US4250267A Immobilized biological material 失效
标题翻译：固定生物材料
公开(公告)号：US4250267A
公开(公告)日：1981-02-10
申请号：US850430
申请日：1977-11-10
申请人： Frank J. Hartdegen , Wayne E. Swann
发明人： Frank J. Hartdegen , Wayne E. Swann
IPC分类号： A61K39/44 , A61K47/48 , C08G18/64 , C12M1/40 , C12N11/08 , C12P1/00 , C12N1/00 , C12N11/04
CPC分类号： A61K47/48215 , A61K39/44 , A61K47/48192 , C08G18/6446 , C12M21/18 , C12M25/14 , C12M25/16 , C12N11/08 , C12P1/00 , Y10S435/80
摘要： A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biological material is contacted with an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological material. The resulting mixture can be cured under foam-forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.
摘要翻译：一种用于固定生物材料的方法，其可以是蛋白质，每分子具有至少一个伯氨基或仲氨基的辅酶，所述辅酶和由所述辅酶介导的酶的混合物，或具有至少一个伯或仲氨基，其中生物材料在不存在水的情况下与过量的异氰酸酯封端的液体聚氨酯预聚物接触，所得混合物通过与固化剂接触固化以固化预聚物并固定生物材料。所得混合物可以在泡沫形成条件下或在非泡沫形成条件下固化。所得混合物可以在固化前或固化期间形成预定形状，或在固化前或固化期间涂覆在表面上。

4. 发明授权

US4237229A Immobilization of biological material with polyurethane polymers 失效
标题翻译：用聚氨酯聚合物固定生物材料
公开(公告)号：US4237229A
公开(公告)日：1980-12-02
申请号：US849990
申请日：1977-11-09
申请人： Frank J. Hartdegen , Wayne E. Swann
发明人： Frank J. Hartdegen , Wayne E. Swann
IPC分类号： A61K39/44 , C08G18/64 , C12N11/08 , C13K1/06 , C13K11/00 , C07G7/02
CPC分类号： C13K11/00 , A61K39/44 , C08G18/6446 , C12N11/08 , C13K1/06
摘要： A process for immobilizing a biological material which can be a protein, a coenzyme having at least one primary or secondary amino group per molecule, an admixture of said coenzyme and an enzyme which is mediated by said coenzyme, or an antibiotic having at least one primary or secondary amino group per molecule, wherein the biological material is contacted with an excess of an isocyanate-capped liquid polyurethane prepolymer in the absence of water, and the resulting mixture is cured by contacting it with a curing agent to cure the prepolymer and to immobilize the biological material. The resulting mixture can be cured under foam-forming conditions or under nonfoam-forming conditions. The resulting mixture can be formed into a predetermined shape before or during curing or coated onto a surface before or during curing.
摘要翻译：一种用于固定生物材料的方法，其可以是蛋白质，每分子具有至少一个伯氨基或仲氨基的辅酶，所述辅酶和由所述辅酶介导的酶的混合物，或具有至少一个伯或仲氨基，其中生物材料在不存在水的情况下与过量的异氰酸酯封端的液体聚氨酯预聚物接触，所得混合物通过与固化剂接触固化以固化预聚物并固定生物材料。所得混合物可以在泡沫形成条件下或在非泡沫形成条件下固化。所得混合物可以在固化前或固化期间形成预定形状，或在固化前或固化期间涂覆在表面上。

5. 发明授权

US4504582A Vermiculite as a carrier support for immobilized biological materials 失效
标题翻译：蛭石作为载体支持固定生物材料
公开(公告)号：US4504582A
公开(公告)日：1985-03-12
申请号：US464376
申请日：1983-02-07
申请人： Wayne E. Swann
发明人： Wayne E. Swann
IPC分类号： C12N11/04 , C12N11/14 , C12P13/20 , C12P13/22 , A61K9/28
CPC分类号： C12N11/14 , C12N11/04 , C12P13/20 , C12P13/22
摘要： Biological materials are immobilized by being absorbed into vermiculite particles which then are coated with a polymeric coating material. A variety of cross-linking, condensing, and gelling agents may be used to strengthen and crosslink the polymer.
摘要翻译：生物材料通过被蛭石颗粒吸收固定，然后用聚合物涂层材料涂覆。可以使用各种交联，缩合和胶凝剂来增强和交联聚合物。

6. 发明授权

US4434228A Immobilization of biological materials in condensed polyalkyleneimine polymers 失效
标题翻译：生物材料在缩聚聚亚烷基亚胺聚合物中的固定
公开(公告)号：US4434228A
公开(公告)日：1984-02-28
申请号：US370242
申请日：1982-04-20
申请人： Wayne E. Swann
发明人： Wayne E. Swann
IPC分类号： C08G73/04 , C12N11/08 , C12P13/20 , C12P13/22 , C12N11/04
CPC分类号： C12P13/22 , C12N11/08 , C12P13/20
摘要： Biological materials are immobilized within condensed polyalkyleneimine polymers. Condensation of the polymer is accomplished by bridging the amine groups of polyalkyleneimine polymer chains with a polycarboxylic acid, in the presence of a condensing agent. d
摘要翻译：生物材料固定在缩聚聚亚烷基亚胺聚合物中。聚合物的缩合是通过在缩合剂存在下使聚亚烷基亚胺聚合物链的胺基与多元羧酸桥连来实现的。

7. 发明授权

US4610800A Method for unclogging drainage pipes 失效
标题翻译：排水管不堵塞的方法
公开(公告)号：US4610800A
公开(公告)日：1986-09-09
申请号：US695219
申请日：1985-01-25
申请人： Donald Durham , J. Leslie Glick , Douglas W. Fodge , Wayne E. Swann
发明人： Donald Durham , J. Leslie Glick , Douglas W. Fodge , Wayne E. Swann
IPC分类号： C11D3/22 , C11D3/386 , C11D11/00 , C11D7/42 , D06M16/00
CPC分类号： C11D11/0041 , C11D3/222 , C11D3/38645
摘要： Drainage pipes, such as toilet drains, which are clogged with cellulosic paper products, are unclogged by contacting the paper with a cellulase enzyme in the form of an aqueous solution, a viscous fluid comprising the enzyme dispersed in a non-cellulosic water-soluble natural or synthetic gum, or solid particles comprising the enzyme dispersed in a water-soluble polymer.
摘要翻译：将纤维素纸制品堵塞的排水管如厕所排水管以水溶液的形式接触纸与纤维素酶而消失，粘性流体包含分散在非纤维素水溶性天然物中的酶或合成胶，或包含分散在水溶性聚合物中的酶的固体颗粒。

8. 发明授权

US4195127A Process for immobilizing proteins 失效
标题翻译：固定蛋白质的方法
公开(公告)号：US4195127A
公开(公告)日：1980-03-25
申请号：US851932
申请日：1977-11-16
申请人： Frank J. Hartdegen , Wayne E. Swann
发明人： Frank J. Hartdegen , Wayne E. Swann
IPC分类号： A61K39/44 , C08G18/64 , C12N11/08 , C13K1/06 , C13K11/00 , C07G7/00 , C07G7/02
CPC分类号： A61K39/44 , C08G18/6446 , C12N11/08 , C13K1/06 , C13K11/00 , Y10S530/817 , Y10S530/868
摘要： A protein which can be an enzyme is immobilized by: (a) admixing the protein and an isocyanate-capped liquid polyurethane prepolymer to form an intermediate product; and (b) foaming the intermediate product by reacting it with water to form a polyurethane foam comprising the immobilized enzyme.
摘要翻译：可以通过以下方法固定可以作为酶的蛋白质：（a）将蛋白质和异氰酸酯封端的液体聚氨酯预聚物混合以形成中间产物; 和（b）通过使其与水反应来使中间产物发泡以形成包含固定化酶的聚氨酯泡沫。

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