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1. 发明申请

US20070233183A1 SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 有权
公开(公告)号：US20070233183A1
公开(公告)日：2007-10-04
申请号：US11762410
申请日：2007-06-13
申请人： Eamon BRADY , David Vale , Ronald Kellly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon BRADY , David Vale , Ronald Kellly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/2212 , A61B2017/2215 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0093
摘要： A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.

2. 发明申请

US20070233179A1 SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 审中-公开
公开(公告)号：US20070233179A1
公开(公告)日：2007-10-04
申请号：US11762193
申请日：2007-06-13
申请人： Eamon BRADY , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon BRADY , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/2212 , A61B2017/2215 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/0093
摘要： A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.

3. 发明申请

US20070225752A1 SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 审中-公开
公开(公告)号：US20070225752A1
公开(公告)日：2007-09-27
申请号：US11753928
申请日：2007-05-25
申请人： Paul GILSON , Michael GILVARRY , Eamon BRADY , David VALE , Steven HORAN
发明人： Paul GILSON , Michael GILVARRY , Eamon BRADY , David VALE , Steven HORAN
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient. The filter element comprising a collapsible filter body and a filter support frame contacting the filter body. The collapsible filter body has an inlet end and an outlet end, the inlet end of the filter body having one or more inlet openings sized to allow blood and embolic material to enter the filter body, the outlet end of the filter body having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter body. The filter support frame is movable between a collapsed position for movement through the vascular system and an extended outwardly projecting position to support the filter body in the expanded position. The frame has a plurality of engagement segments which are spaced-apart longitudinally and transversely when the filter body is in the deployed expanded configuration to urge the filter body into opposition with the vessel wall. The engagement segments define at least partially a substantially helical engagement track.

4. 发明申请

US20070250107A1 EMBOLIC PROTECTION SYSTEM 有权
公开(公告)号：US20070250107A1
公开(公告)日：2007-10-25
申请号：US11739713
申请日：2007-04-25
申请人： Paul GILSON , Charles TAYLOR , Patrick GRIFFIN , Michael GILVARRY , David VALE , Eamon BRADY
发明人： Paul GILSON , Charles TAYLOR , Patrick GRIFFIN , Michael GILVARRY , David VALE , Eamon BRADY
IPC分类号： A61M29/00
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An assembly for loading a collapsible embolic protection filter 1 into a catheter 2, comprises a catheter 2 defining a reception space at a distal end of the catheter 2 for receiving a collapsed embolic protection filter 1; and a separate removable pushing device 8 for delivering the embolic protection filter 1 into the reception space. The pushing device 8 comprises an elongate stem 71 with a proximal stop 72 for engagement with the filter 1. A separate loading device 7 to collapse the embolic protection filter 1 is also provided. The loading device 7 defines an inlet end and an outlet end, the outlet end being configured for co-operative alignment with the reception space.

5. 发明申请

US20110307002A1 EMBOLIC PROTECTION SYSTEM 审中-公开
标题翻译：嵌入式保护系统
公开(公告)号：US20110307002A1
公开(公告)日：2011-12-15
申请号：US13152516
申请日：2011-06-03
申请人： Paul GILSON , Charles TAYLOR , Patrick GRIFFIN , John NIELSEN , David VALE , Eamon BRADY
发明人： Paul GILSON , Charles TAYLOR , Patrick GRIFFIN , John NIELSEN , David VALE , Eamon BRADY
IPC分类号： A61F2/01
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection system having a guidewire for advancing through a vasculature; an embolic protection filter having a filter body with a distal end and a proximal end, the filter body providing for a collapsed configuration and an expanded deployed configuration. The embolic protection filter body has a guidewire path for slidably receiving the guidewire to permit movement of the filter relative to the guidewire when the filter 1 is in the collapsed configuration and the expanded deployed configuration. A delivery catheter is advanceable over the guidewire for delivery of the embolic protection filter. A retrieval catheter is also advancable over the guidewire for retrieval of the filter, and engagement elements are used for engaging the embolic protection filter with the guidewire for retrieval of the filter into the retrieval catheter in the collapsed configuration.
摘要翻译：具有用于前进通过脉管系统的导丝的栓塞保护系统; 一种具有过滤体的栓塞保护过滤器，其具有远端和近端，所述过滤器主体提供收缩构型和展开展开构造。栓塞保护过滤器主体具有用于可滑动地接收导丝的导丝路径，以允许过滤器1处于折叠构型和展开展开构型时相对于导丝移动。输送导管可在引导线上前进，用于输送栓塞保护过滤器。导管还可以通过引导线用于取出过滤器，并且接合元件用于将栓塞保护过滤器与引导线接合，以将滤器以折叠构型取回到回收导管中。

6. 发明申请

US20110276120A1 Vascular Device For Use During An Interventional Procedure 有权
标题翻译：介入手术期间使用的血管装置
公开(公告)号：US20110276120A1
公开(公告)日：2011-11-10
申请号：US13183583
申请日：2011-07-15
申请人： Paul GILSON , Eamon BRADY , Padraig MAHER , David VALE , Charles TAYLOR
发明人： Paul GILSON , Eamon BRADY , Padraig MAHER , David VALE , Charles TAYLOR
IPC分类号： A61F2/84
CPC分类号： A61F2/01 , A61B2017/22051 , A61B2017/22067 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0069 , A61F2230/0093 , A61F2230/0097
摘要： A vascular device for use during an interventional procedure, the device having a stent structure having a collapsed configuration, an expanded configuration, a proximal end, and a distal end; and a delivery member for delivering the stent to a treatment site within a vasculature, wherein the proximal end of the stent structure is fixed to the delivery member when the stent structure is in the expanded configuration at the treatment site.
摘要翻译：一种在介入手术期间使用的血管装置，所述装置具有具有收缩构型的支架结构，扩张构型，近端和远端; 以及用于将支架输送到脉管系统内的治疗部位的输送部件，其中当支架结构在处理部位处于扩张构型时，支架结构的近端固定到输送部件。

7. 发明申请

US20090209997A1 MEDICAL DEVICE 有权
标题翻译：医疗装置
公开(公告)号：US20090209997A1
公开(公告)日：2009-08-20
申请号：US12212292
申请日：2008-09-17
申请人： Eamon BRADY , Ronald Kelly
发明人： Eamon BRADY , Ronald Kelly
IPC分类号： A61B17/22
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： A collapsible filter element (40) for a transcatheter embolic protection device (1). The filter element (40) comprises a collapsible filter body (41) which is movable between a collapsed stored position for movement through a vascular system and an expanded position for extension across a blood vessel such that blood passing through the blood vessel is delivered through the filter element (40). A proximal inlet portion of the filter body (41) has two inlet openings (50) sized to allow blood and embolic material enter the filter body (41), and a distal outlet portion of the filter body (41) has a plurality of small outlet openings (51) to allow through-passage of blood, but to retain embolic material within the filter body (41). The filter body (41) is of an oriented polymeric material.
摘要翻译：一种用于经导管栓塞保护装置（1）的可折叠过滤元件（40）。过滤器元件（40）包括可折叠的过滤器主体（41），其可在通过血管系统移动的折叠存储位置和用于延伸穿过血管的扩张位置之间移动，使得通过血管的血液通过过滤元件（40）。过滤器主体（41）的近侧入口部分具有两个入口开口（50），其尺寸允许血液和栓塞物质进入过滤器主体（41），并且过滤器主体（41）的远端出口部分具有多个小的出口开口（51）以允许血液通过，但是将栓塞材料保持在过滤体（41）内。过滤体（41）是定向聚合材料。

8. 发明申请

US20090163612A1 TISSUE ENGINEERING SCAFFOLD 有权
标题翻译：组织工程SCAFFOLD
公开(公告)号：US20090163612A1
公开(公告)日：2009-06-25
申请号：US12271336
申请日：2008-11-14
申请人： Eamon BRADY , Ann Marie Cannon , Fergal Farrell , Gerard McCaffrey
发明人： Eamon BRADY , Ann Marie Cannon , Fergal Farrell , Gerard McCaffrey
IPC分类号： C08G18/76 , C08G18/00
CPC分类号： C12N5/0068 , A61L29/06 , A61L29/146 , A61L31/06 , A61L31/146 , C08G18/10 , C08G18/48 , C08G2101/00 , C08G2101/0008 , C08G2101/0083 , C12N2531/00 , C12N2533/30 , C08L75/08 , C08G18/32
摘要： A tissue engineering scaffold for cell, tissue or organ growth comprises a biocompatible porous polyurethane cellular material comprising a plurality of substantially spherical voids of diameter from 20 to 300 microns, preferably 80 to 200 microns, interconnected by generally elliptically shaped pores. The cellular material has a void content of from 85% to 98% and a surface area to volume of from 5 to 400 mm2/mm3, ideally from 20 to 80 mm2/mm3.
摘要翻译：用于细胞，组织或器官生长的组织工程支架包括生物相容性多孔聚氨酯多孔材料，其包含直径为20至300微米，优选为80至200微米的多个基本上球形的空隙，通过大致椭圆形的孔互连。多孔材料具有85％至98％的空隙含量和5至400mm 2 / mm 3的表面积至体积，理想地为20至80mm 2 / mm 3。

9. 发明申请

US20110125182A1 FILTER ELEMENT WITH RETRACTABLE GUIDEWIRE TIP 有权
标题翻译：过滤元件带有可缩回的指南
公开(公告)号：US20110125182A1
公开(公告)日：2011-05-26
申请号：US13022040
申请日：2011-02-07
申请人： Eamon BRADY
发明人： Eamon BRADY
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： A medical guidewire assembly comprises a guidewire having a flexible tip. A medical device such as a collapsible filter for use as an embolic protection device is mounted on the guidewire. The filter is advanced through a body lumen with the guidewire tip extending distally. A variable thickness guidewire (having a recess or thinner segment between thicker segments) can be employed. At a first location the filter is advanced relative to the tip to a location which is distally advanced from the first location. Placement of the filter in an optimal distal location is thereby achieved.
摘要翻译：医疗导丝组件包括具有柔性末端的导丝。诸如用作栓塞保护装置的可折叠过滤器的医疗装置安装在导丝上。过滤器前进通过体腔，导丝末端向远端延伸。可以使用可变厚度的导丝（在较厚的部分之间具有凹部或更薄的部分）。在第一位置，过滤器相对于尖端前进到从第一位置向远侧前进的位置。由此实现过滤器在最佳远侧位置的放置。

10. 发明申请

US20090099594A1 FILTER ELEMENT WITH RETRACTABLE GUIDEWIRE TIP 有权
标题翻译：过滤元件带有可缩回的指南
公开(公告)号：US20090099594A1
公开(公告)日：2009-04-16
申请号：US12339375
申请日：2008-12-19
申请人： Eamon BRADY
发明人： Eamon BRADY
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： A medical guidewire assembly comprises a guidewire having a flexible tip. A medical device such as a collaptible filter for use as an embolic protection device is mounted on the guidewire. The filter is advanced through a body lumen with the guidewire tip extending distally. At a first location the filter is advanced relative to the tip to a location which is distally advanced from the first location. Placement of the filter in an optimal distal location is thereby achieved.
摘要翻译：医疗导丝组件包括具有柔性末端的导丝。诸如用于栓塞保护装置的可折叠过滤器的医疗装置安装在导丝上。过滤器前进通过体腔，导丝末端向远端延伸。在第一位置，过滤器相对于尖端前进到从第一位置向远侧前进的位置。由此实现过滤器在最佳远侧位置的放置。

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