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1. 发明申请

WO2002092790A1 KIMCHI LACTIC ACID BACTERIA GROUP HINDERING GROWTH OF HELICOBACTOR PYLOLI AND HIGH FUNCTIONAL FOOD PROTECTING GASTROENTERIC DISORDER THEREWITH 审中-公开
标题翻译： KIMCHI LACTIC ACID BACTERIA GROUP HINGICOBACTOR PYLOLI和高功能食品保护胃肠疾病的发展
公开(公告)号：WO2002092790A1
公开(公告)日：2002-11-21
申请号：PCT/KR2002/000899
申请日：2002-05-14
申请人： EUGENE SCIENCE INC. , KIM, Chang-Gon , CHO, Jang-Hyun , LEE, Young-Sun , KIM, Myung-Kuk , YOON, Won-Tae
发明人： KIM, Chang-Gon , CHO, Jang-Hyun , LEE, Young-Sun , KIM, Myung-Kuk , YOON, Won-Tae
IPC分类号： C12N1/20
CPC分类号： C12N1/20
摘要： The present invention relates to Kimchi lactic acid bacteria that inhibit growth of Helicobactor pylori, and foods comprising the same, and particularly to a gastrointestinal-tract-protecting high functional food comprising Kimchi lactic acid bacteria that inhibits attachment of Helicobactor pylori to the gastrointestinal tract, and inhibits growth thereof. The Kimchi lactic acid bacteria of the present invention inhibits attachment of Helicobactor pylori that inhabit the gastric mucous membrane tissue of the gastrointestinal tract, and inhibits growth thereof, and thus are very effective for Helicobactor pylori extermination and prevention of reinfection therefrom. In addition, a gastrointestinal-tract-protecting high functional food comprising the Kimchi lacti acid bacteria is very effective for preventing and treating gastritis, peptic ulcers, and duodenal ulcers caused by Helicobactor pylori.
摘要翻译：本发明涉及抑制幽门螺旋杆菌生长的泡菜乳酸菌，以及包含该泡菜的食品，尤其涉及抑制幽门螺杆菌对胃肠道附着的泡菜乳酸菌的胃肠道保护性高功能食品，并抑制其生长。本发明的泡菜乳酸菌抑制居住在胃肠道胃粘膜组织的幽门螺杆菌幽门螺杆菌的附着，抑制其生长，因此对于幽门螺杆菌幽门螺杆菌灭活和防止其再次感染是非常有效的。此外，包含泡菜乳酸菌的胃肠道保护性高功能食品对于预防和治疗由幽门螺杆菌幽门螺杆菌引起的胃炎，消化性溃疡和十二指肠溃疡是非常有效的。

2. 发明申请

WO2002092789A1 MICROORGANISM HAVING ABILITY TO CONVERT STEROL INTO ANDROST-4-ENE-3,17-DIONE/ANDROSTA-1,4-DIENE-3,17-DIONE AND PREPARATION METHOD AND USE THEREOF 审中-公开
标题翻译：具有将甾体转化成安非他酮-4-烯-3,17-二酮/安息香-1,4-二烯-3,17-二酮的能力的微生物及其制备方法及其用途
公开(公告)号：WO2002092789A1
公开(公告)日：2002-11-21
申请号：PCT/KR2002/000875
申请日：2002-05-10
申请人： EUGENE SCIENCE INC. , NOH, Seung-Kwon , KIM, Myung-Kuk , YOON, Won-Tae , PARK, Kyung-Moon , PARK, Sang-Ok
发明人： NOH, Seung-Kwon , KIM, Myung-Kuk , YOON, Won-Tae , PARK, Kyung-Moon , PARK, Sang-Ok
IPC分类号： C12N1/20
CPC分类号： C12P33/00 , C12N1/20
摘要： Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly, a mutant strain of Mycobacterium fortuitum ATCC 29472, Mycobacterium fortuitum EUG-119, a method for preparation of the mutant and use thereof in preparing AD and ADD. The mutant of the present invention has an excellent ability to convert sterol into AD and ADD which are steroid hormone precursors, compared with the known microorganisms and accordingly, is very useful for mass production of steroid hormones.
摘要翻译：公开了具有优异的将甾醇转化成罗登-4-烯-3,17-二酮（AD）和雄甾-1,4-二烯-3,17-二酮（ADD）的微生物，其制备方法微生物及其用途，更具体地，是偶发分枝杆菌ATCC 29472，偶发分枝杆菌EUG-119的突变菌株，制备突变体的方法及其在制备AD和ADD中的用途。与已知的微生物相比，本发明的突变体具有优异的将甾醇转化成AD和ADD的能力，其与类固醇激素前体相比，因此对于大量生产类固醇激素非常有用。

3. 发明申请

WO2002092830A1 A METHOD FOR PREPARATION OF ANDROST-4-ENE-3,17-DIONE AND ANDROSTA-1,4-DIENE-3,17-DIONE 审中-公开
标题翻译：安培罗-4-烯-3,17-二酮和安息香-1,4-二烯-3,17-二酮的制备方法
公开(公告)号：WO2002092830A1
公开(公告)日：2002-11-21
申请号：PCT/KR2002/000876
申请日：2002-05-10
申请人： EUGENE SCIENCE INC. , NOH, Seung-Kwon , KIM, Myung-Kuk , YOON, Won-Tae , PARK, Kyung-Moon , PARK, Sang-Ok
发明人： NOH, Seung-Kwon , KIM, Myung-Kuk , YOON, Won-Tae , PARK, Kyung-Moon , PARK, Sang-Ok
IPC分类号： C12P33/16
CPC分类号： C12P33/16
摘要： The present invention relates to a method for preparation of androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). More particularly, the present invention relates to a method for preparing AD/ADD, comprising the steps of: (a) heating sterols and emulsifier respectively, to dissolve completely and mixing to prepare a mixture; (b) placing the mixture in a water bath at 70 ∼90°C and stirring to obtain emulsified sterols; and (c) adding the emulsified sterols to culture media of microorganism as a component. And the present invention relates to a method for preparing AD/ADD, comprising the addition of cyclodextrin-sterol complexes extracted from milk to culture media of microorganism as a component. The emulsified sterols and cyclodextrin-sterol complexes adopted in the present invention can be easily prepared and be effectively used for obtaining AD/ADD at a high yield.
摘要翻译：雄甾-4-烯-3,17-二酮（AD）和雄甾-1,4-二烯-3,17-二酮（ADD）的制备方法技术领域本发明涉及雄甾-4-烯-3,17-二酮（AD）和雄甾-1,4-二烯-3,17-二酮（ADD）的制备方法。更具体地说，本发明涉及一种制备AD / ADD的方法，包括以下步骤：（a）分别加热固醇和乳化剂以完全溶解并混合以制备混合物; （b）将混合物置于70℃的水浴中并搅拌以获得乳化的甾醇; 和（c）将乳化的甾醇加入作为组分的微生物培养基中。本发明涉及AD / ADD的制备方法，其特征在于，将从乳中提取的环糊精 - 甾醇配合物添加到微生物的培养基中作为成分。本发明中采用的乳化甾醇和环糊精 - 固醇配合物可以容易地制备并且有效地用于以高产率获得AD / ADD。

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