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1. 发明申请

WO2018156223A1 MIXED GAS INTEGRITY TESTING OF POROUS MATERIALS WITHOUT PERMEATE SIDE ACCESS 审中-公开
公开(公告)号：WO2018156223A1
公开(公告)日：2018-08-30
申请号：PCT/US2017/062518
申请日：2017-11-20
申请人： EMD MILLIPORE CORPORATION
发明人： GIGLIA, Salvatore
IPC分类号： B01D65/10 , G01N15/08 , B01D61/38
摘要： A method of integrity testing porous materials that is non-destructive to the material being tested. The inlet gas stream includes at least two gases, wherein one of the gases has a different permeability in liquid than the other, such as oxygen and nitrogen in water. The relative permeability of the gases is measured in the retentate stream, thereby avoiding accessing the permeate stream and potentially introducing contaminants to the material being tested. The integrity test is capable of detecting the presence of oversized pores or defects that can compromise the retention capability of the porous material.

2. 发明申请

WO2022146704A1 SECONDARY STATISTICAL CUTOFF METHODOLOGY FOR GAS-LIQUID DIFFUSION INTEGRITY TESTING 审中-公开
公开(公告)号：WO2022146704A1
公开(公告)日：2022-07-07
申请号：PCT/US2021/063763
申请日：2021-12-16
申请人： EMD MILLIPORE CORPORATION
发明人： RODENHISER, Rebecca , GIGLIA, Salvatore , JOHNSON, Christopher
IPC分类号： B01D65/10 , G01N15/08
摘要： The disclosure herein relates to a method of reducing background noise during integrity testing of membrane filter to increase sensitivity and more effectively disposition failing membrane filters.

3. 发明申请

WO2018044648A1 FIXED RIGID WALL DEVICE FOR COMPRESSED PLEAT CONFIGURATION FILTERS 审中-公开
标题翻译：用于压缩PLEAT配置过滤器的固定刚性壁装置
公开(公告)号：WO2018044648A1
公开(公告)日：2018-03-08
申请号：PCT/US2017/048193
申请日：2017-08-23
申请人： EMD MILLIPORE CORPORATION
发明人： LIU, Songhua , LYNCH, Michael , SYLVIA, Ryan , ALMASIAN, Joseph , GIGLIA, Salvatore , MESSIER, Luc
IPC分类号： B01D46/00 , B01D35/00 , B01D35/30 , B01D46/04
摘要： A scaling tool for replicating filtration characteristics of a large-scale filtration device, the scaling tool comprising a housing having a fluid inlet and a fluid outlet, and a filter receiving region in fluid communication with the fluid inlet and the fluid outlet and configured to contain a membrane comprising one or more pleats, the filter receiving region being defined by a rigid wall framework configured to hold the one or more pleats of the membrane and compress the pleats in an amount effective to replicate the filtration performance of the large-scale filtration device. Also disclosed is a methodology for configuring a filter receiving region in a scaling tool.
摘要翻译：一种用于复制大规模过滤装置的过滤特性的定标工具，定标工具包括具有流体入口和流体出口的壳体以及与流体入口流体连通的过滤器接收区域和流体出口并且被构造成容纳包括一个或多个褶皱的膜，所述过滤器接收区域由刚性壁框架限定，刚性壁框架构造成保持膜的一个或多个褶皱并且以有效复制过滤的量压缩褶皱大型过滤装置的性能。还公开了一种用于在缩放工具中配置过滤器接收区域的方法。

4. 发明申请

WO2017087057A1 ENHANCED STABILITY FILTER INTEGRITY TEST 审中-公开
标题翻译：增强的稳定性过滤器完整性测试
公开(公告)号：WO2017087057A1
公开(公告)日：2017-05-26
申请号：PCT/US2016/051268
申请日：2016-09-12
申请人： EMD MILLIPORE CORPORATION
发明人： GIGLIA, Salvatore , NHIEM, David
IPC分类号： G01N15/08 , B01D65/10
CPC分类号： B01D65/10
摘要： A method of integrity testing porous materials that is non-destructive to the material being tested. The method includes humidifying the inlet gas stream to minimize or prevent the porous material from drying out. The inlet gas stream includes at least two gases, wherein one of the gases has a different permeability in liquid than the other, such as oxygen and nitrogen. The permeate gas stream may be subjected to a driving force such as reduced pressure to increase the flow of gases and reduce test time. Multiple porous materials can be integrity tested at the same time, such as by manifolding a plurality of them together. The integrity test is capable of detecting the presence of oversized pores or defects that can compromise the retention capability of the porous material.
摘要翻译：一种完整性测试多孔材料的方法，对被测试材料无损坏。该方法包括加湿入口气流以最小化或防止多孔材料变干。入口气流包括至少两种气体，其中一种气体在液体中具有不同于另一种的渗透性，例如氧气和氮气。渗透气流可以经受诸如减压的驱动力以增加气体流量并减少测试时间。可以同时对多种多孔材料进行完整性测试，例如通过将多个多孔材料分支在一起。完整性测试能够检测到可能损害多孔材料保留能力的超大孔或缺陷的存在。

5. 发明申请

WO2012103124A9 ACCELERATED MIXED GAS INTEGRITY TESTING OF POROUS MATERIALS 审中-公开
公开(公告)号：WO2012103124A9
公开(公告)日：2012-08-02
申请号：PCT/US2012/022409
申请日：2012-01-24
申请人： EMD MILLIPORE CORPORATION , HOA, Jibin , GIGLIA, Salvatore , JOENS, Michael , TUCELLI, Ronald
发明人： HOA, Jibin , GIGLIA, Salvatore , JOENS, Michael , TUCELLI, Ronald
IPC分类号： G01N15/08 , G01N33/44
摘要： The invention relates to accelerated mixed gas integrity testing methods, devices, and systems for integrity testing wetted single and multi-layered porous materials., whereby the testing method is non-destructive to the porous materials being tested. The accelerated mixed gas integrity test method includes one or more of the following components: i) a permeate side gas purge component: ii) a permeate side volume reduction component; and iii) a permeate side circulation component. The invention is directed towards reducing the length of time necessary to complete the integrity testing of single and multilayered porous materials, elements and membranes.

6. 发明公开

EP3503990A1 FIXED RIGID WALL DEVICE FOR COMPRESSED PLEAT CONFIGURATION FILTERS 有权
公开(公告)号：EP3503990A1
公开(公告)日：2019-07-03
申请号：EP17847234.6
申请日：2017-08-23
申请人： EMD Millipore Corporation
发明人： LIU, Songhua , LYNCH, Michael , SYLVIA, Ryan , ALMASIAN, Joseph , GIGLIA, Salvatore , MESSIER, Luc
IPC分类号： B01D46/00 , B01D35/00 , B01D35/30 , B01D46/04

7. 发明公开

EP2668489A2 ACCELERATED MIXED GAS INTEGRITY TESTING OF POROUS MATERIALS 有权转让
标题翻译： BESCHLEUNIGTEUNVERSEHRTHEITSPRÜFUNGPORÖSERMATERIALIEN MITHILFE EINES MISCHGASES
公开(公告)号：EP2668489A2
公开(公告)日：2013-12-04
申请号：EP12738846.0
申请日：2012-01-24
申请人： EMD Millipore Corporation
发明人： HOA, Jibin , GIGLIA, Salvatore , JOENS, Michael , TUCELLI, Ronald
IPC分类号： G01N15/08 , G01N33/44
CPC分类号： B01D46/2411 , B01D46/543 , B01D65/102 , G01N15/082 , G01N2015/084
摘要： The invention relates to accelerated mixed gas integrity testing methods, devices, and systems for integrity testing wetted single and multi-layered porous materials, whereby the testing method is non-destructive to the porous materials being tested. The accelerated mixed gas integrity test method includes one or more of the following components: i) a permeate side gas purge component; ii) a permeate side volume reduction component; and iii) a permeate side circulation component. The invention is directed towards reducing the length of time necessary to complete the integrity testing of single and multi layered porous materials, elements and membranes.
摘要翻译：本发明涉及用于完整性测试润湿的单层和多层多孔材料的加速混合气体完整性测试方法，装置和系统，由此测试方法对被测试的多孔材料是非破坏性的。加速混合气体完整性测试方法包括一种或多种以下组分：i）渗透侧气体吹扫组分; ii）渗透侧体积减少组分; 和iii）渗透侧循环组分。本发明旨在减少完成单层和多层多孔材料，元件和膜的完整性测试所需的时间长度。

8. 发明公开

EP3585507A1 MIXED GAS INTEGRITY TESTING OF POROUS MATERIALS WITHOUT PERMEATE SIDE ACCESS 有权
公开(公告)号：EP3585507A1
公开(公告)日：2020-01-01
申请号：EP17897891.2
申请日：2017-11-20
申请人： EMD Millipore Corporation
发明人： GIGLIA, Salvatore
IPC分类号： B01D65/10 , G01N15/08 , B01D61/38

9. 发明公开

EP3377875A1 ENHANCED STABILITY FILTER INTEGRITY TEST 审中-实审
公开(公告)号：EP3377875A1
公开(公告)日：2018-09-26
申请号：EP16866797.0
申请日：2016-09-12
申请人： EMD Millipore Corporation
发明人： GIGLIA, Salvatore , NHIEM, David
IPC分类号： G01N15/08 , B01D65/10
CPC分类号： B01D65/102 , B01D65/10 , G01N15/0826 , G01N2015/084
摘要： A method of integrity testing porous materials that is non-destructive to the material being tested. The method includes humidifying the inlet gas stream to minimize or prevent the porous material from drying out. The inlet gas stream includes at least two gases, wherein one of the gases has a different permeability in liquid than the other, such as oxygen and nitrogen. The permeate gas stream may be subjected to a driving force such as reduced pressure to increase the flow of gases and reduce test time. Multiple porous materials can be integrity tested at the same time, such as by manifolding a plurality of them together. The integrity test is capable of detecting the presence of oversized pores or defects that can compromise the retention capability of the porous material.

10. 发明公开

EP4271506A1 SECONDARY STATISTICAL CUTOFF METHODOLOGY FOR GAS-LIQUID DIFFUSION INTEGRITY TESTING 审中-实审
公开(公告)号：EP4271506A1
公开(公告)日：2023-11-08
申请号：EP21848353.5
申请日：2021-12-16
申请人： EMD Millipore Corporation
发明人： RODENHISER, Rebecca , GIGLIA, Salvatore , JOHNSON, Christopher
IPC分类号： B01D65/10 , G01N15/08

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